Page last updated: 2024-10-28

haloperidol and ADDH

haloperidol has been researched along with ADDH in 31 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Research Excerpts

ExcerptRelevanceReference
"Pimozide, a dopamine receptor antagonist, dopamine uptake inhibitor and L-type calcium channel blocker, is used in children suffering from Tourette syndrome (TS), but its effect on frequently comorbid attention deficit hyperactivity disorder (ADHD) is unknown."9.07Effects of pimozide on cognition in children with Tourette syndrome: interaction with comorbid attention deficit hyperactivity disorder. ( Rock, CM; Sallee, FR; Sethuraman, G, 1994)
"Erythrocyte and plasma choline parameters were compared in children (n = 63), aged 6-18 years, suffering from Tourette Syndrome (TS), their parents (n = 57), their unaffected siblings (n = 38), and an adult control group (n = 57)."7.68Controlled study of erythrocyte choline in Tourette syndrome. ( Hanin, I; Kopp, U; Sallee, FR, 1992)
"The effect of methylphenidate preceded by a moderate dose of haloperidol on reaction times over the duration of a continuous performance test (CPT), was investigated in ten male children, with a DSM-III diagnosis of attention deficit disorder with hyperactivity disorder (ADDH)."5.08Does haloperidol block methylphenidate? Motivation or attention? ( Hobbes, G; Levy, F, 1996)
"Pimozide, a dopamine receptor antagonist, dopamine uptake inhibitor and L-type calcium channel blocker, is used in children suffering from Tourette syndrome (TS), but its effect on frequently comorbid attention deficit hyperactivity disorder (ADHD) is unknown."5.07Effects of pimozide on cognition in children with Tourette syndrome: interaction with comorbid attention deficit hyperactivity disorder. ( Rock, CM; Sallee, FR; Sethuraman, G, 1994)
" Withdrawal of the narcolepsy treatment and initiation of haloperidol 1 mg/day (the only antipsychotic treatment she could tolerate) improved the delusions, hallucinations and dysphoria but worsened the narcolepsy symptoms."3.85Narcolepsy-cataplexy and psychosis: a case study. ( Arango-Lopez, C; Canellas-Dols, F; Delgado, C; Peraita-Adrados, R, 2017)
"Erythrocyte and plasma choline parameters were compared in children (n = 63), aged 6-18 years, suffering from Tourette Syndrome (TS), their parents (n = 57), their unaffected siblings (n = 38), and an adult control group (n = 57)."3.68Controlled study of erythrocyte choline in Tourette syndrome. ( Hanin, I; Kopp, U; Sallee, FR, 1992)
"The prognosis of CCI patients with coma or delirium has not yet been thoroughly studied, but preliminary studies suggest this population is at high risk for detrimental outcomes associated with acute brain dysfunction."2.48Brain dysfunction in patients with chronic critical illness. ( Girard, TD, 2012)
"Clonidine was associated with markedly higher clinical efficacy vs."1.91Efficacy of clonidine in the treatment of children with tic disorder co-morbid with attention deficit hyperactivity disorder. ( Hu, B; Huang, XH; Wang, GL; Yuan, Y; Zeng, KD; Zhang, W, 2023)
"Although choreiform movements were reported in adults with amphetamine abuse and in those under therapeutic treatment for attention deficit hyperactivity disorder, previous literature concerning the pediatric population is spare."1.38Acute, sustained chorea in children after supratherapeutic dosing of amphetamine-derived medications. ( Albertson, TE; Ford, JB; McKinney, WB; Owen, KP; Sutter, ME, 2012)
"Tourette syndrome is a neuropsychiatric disorder of motor and vocal tics, with associated symptoms of obsessive-compulsive behaviors and attention deficit disorder with hyperactivity."1.27[The treatment of children with Gilles de la Tourette's syndrome]. ( Minderaa, RB, 1987)
"Early signs of Tourette's syndrome may be difficult to distinguish from hyperactive and attention disordered symptoms, leading the clinician to consider, treatment with stimulants."1.26Stimulant medications precipitate Tourette's syndrome. ( Cohen, DJ; Detlor, J; Kremenitzer, MW; Lowe, TL; Shaywitz, BA, 1982)
"It is the drug of choice for Tourette's syndrome, and may be useful in nonpsychotic hyperactive or aggressive children to control acute episodes, or when the stimulants normally useful in hyperactive children are ineffective."1.26Haloperidol -- its use in children. ( Serrano, AC, 1981)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199015 (48.39)18.7374
1990's6 (19.35)18.2507
2000's5 (16.13)29.6817
2010's3 (9.68)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Lages, YV1
Maisonnette, SS1
Rosseti, FP1
Galvão, BO1
Landeira-Fernandez, J1
Zeng, KD1
Wang, GL1
Yuan, Y1
Zhang, W1
Huang, XH1
Hu, B1
Canellas-Dols, F1
Delgado, C1
Arango-Lopez, C1
Peraita-Adrados, R1
Girard, TD1
Ford, JB1
Albertson, TE1
Owen, KP1
Sutter, ME1
McKinney, WB1
Kano, Y1
Shintani, N1
Tanaka, K1
Hashimoto, H1
Baba, A1
Terranova, JP1
Chabot, C1
Barnouin, MC1
Perrault, G1
Depoortere, R1
Griebel, G1
Scatton, B1
Machida, N1
Shiotsuka, S1
Semba, J1
Xu, XB1
Liu, HJ1
Peng, JH1
Lowe, TL1
Cohen, DJ4
Detlor, J1
Kremenitzer, MW1
Shaywitz, BA1
Comings, DE1
Comings, BG1
Conn, LM1
Lion, JR1
Leckman, JF3
Bruun, RD1
Serrano, AC1
Bachman, DS1
McKay, B1
Sallee, FR2
Sethuraman, G1
Rock, CM1
Levy, F2
Hobbes, G2
Brasić, JR1
Barnett, JY1
Bellak, L1
Kopp, U1
Hanin, I1
Riddle, MA1
Rubenstein, JL1
Johnston, K1
Elliott, GR1
Brusilow, SW1
Taylor, E1
Price, RA1
Pauls, DL1
Kidd, KK1
Gualtieri, CT1
Patterson, DR1
Minderaa, RB1
Caine, ED1
McBride, MC1
Chiverton, P1
Bamford, KA1
Rediess, S1
Shiao, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00004325]200 participants Observational1988-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for haloperidol and ADDH

ArticleYear
Brain dysfunction in patients with chronic critical illness.
    Respiratory care, 2012, Volume: 57, Issue:6

    Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Chronic Disease; Coma; Comorbid

2012
[Chronic tic disorders--chronic mortor or vocal tic disorders and de la Tourette's syndrome].
    Ryoikibetsu shokogun shirizu, 2003, Issue:40

    Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sy

2003
Pharmacologic approaches to violence.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Be

1984
Recent advances in Gilles de la Tourette syndrome: implications for clinical practice and future research.
    Psychiatric developments, 1983,Autumn, Volume: 1, Issue:3

    Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Compulsive

1983
Pharmacotherapy of Tourette's syndrome and associated disorders.
    The Psychiatric clinics of North America, 1992, Volume: 15, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Clonidine; Female; Haloperidol; Humans; Male; Mental

1992

Trials

4 trials available for haloperidol and ADDH

ArticleYear
[Comparative observation on acupuncture and western medicine for treatment of minimal brain dysfunction].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2007, Volume: 27, Issue:12

    Topics: Acupuncture Therapy; Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Female; Halop

2007
Effects of pimozide on cognition in children with Tourette syndrome: interaction with comorbid attention deficit hyperactivity disorder.
    Acta psychiatrica Scandinavica, 1994, Volume: 90, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Calcium Channels; Child; Cognition; Dose-

1994
Does haloperidol block methylphenidate? Motivation or attention?
    Psychopharmacology, 1996, Volume: 126, Issue:1

    Topics: Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Dopamine Agents; Dopamin

1996
The action of stimulant medication in attention deficit disorder with hyperactivity: dopaminergic, noradrenergic, or both?
    Journal of the American Academy of Child and Adolescent Psychiatry, 1988, Volume: 27, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Drug Therapy, Combination; H

1988

Other Studies

22 other studies available for haloperidol and ADDH

ArticleYear
Haloperidol and methylphenidate alter motor behavior and responses to conditioned fear of Carioca Low-conditioned Freezing rats.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 211

    Topics: Animals; Anxiety; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Conditioning, Psy

2021
Efficacy of clonidine in the treatment of children with tic disorder co-morbid with attention deficit hyperactivity disorder.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:9

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Clonidine;

2023
Narcolepsy-cataplexy and psychosis: a case study.
    Revista de neurologia, 2017, Jul-16, Volume: 65, Issue:2

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Benzhydryl Compound

2017
Acute, sustained chorea in children after supratherapeutic dosing of amphetamine-derived medications.
    Pediatric neurology, 2012, Volume: 47, Issue:3

    Topics: Amphetamines; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous S

2012
[Altered behavioral response to centrally acting drugs in mice lacking PACAP].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2003, Volume: 122 Suppl

    Topics: Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Disease Model

2003
SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist, alleviates disturbances of novelty discrimination in a social context in rats, a putative model of selective attention deficit.
    Psychopharmacology, 2005, Volume: 181, Issue:1

    Topics: Age Factors; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Clozapine; De

2005
[Case of obsessive-compulsive disorder associated with neuroleptics-induced deficit syndrome (NIDS): successfully treated by discontinuation of neuroleptics followed by SSRI].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2005, Volume: 107, Issue:7

    Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Fluvoxamine; Haloperidol; Human

2005
Stimulant medications precipitate Tourette's syndrome.
    JAMA, 1982, Feb-26, Volume: 247, Issue:8

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dextroamphe

1982
Tourette's syndrome and attention deficit disorder with hyperactivity: are they genetically related?
    Journal of the American Academy of Child Psychiatry, 1984, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimu

1984
Gilles de la Tourette's syndrome. An overview of clinical experience.
    Journal of the American Academy of Child Psychiatry, 1984, Volume: 23, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Clonidine; Compu

1984
Haloperidol -- its use in children.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Dose-Response Relationship, Drug; Haloperidol;

1981
Pemoline-induced Tourette's disorder: a case report.
    The American journal of psychiatry, 1981, Volume: 138, Issue:8

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Diseases in Twins; Haloperidol; Humans; M

1981
Haloperidol (Serenace) use in 'childhood dislocation anxiety'.
    Australian family physician, 1980, Volume: 9, Issue:12

    Topics: Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; C

1980
Hyperkinesias in a prepubertal boy with autistic disorder treated with haloperidol and valproic acid.
    Psychological reports, 1997, Volume: 80, Issue:1

    Topics: Anti-Dyskinesia Agents; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Autistic Dis

1997
A possible subgroup of the schizophrenic syndrome and implications for treatment.
    American journal of psychotherapy, 1976, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Diazepam; Dominance, Cerebral; Dys

1976
Controlled study of erythrocyte choline in Tourette syndrome.
    Biological psychiatry, 1992, Jun-15, Volume: 31, Issue:12

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Choline; Drug Therapy, Combination

1992
Haloperidol-induced hyperammonaemia in a child with citrullinaemia.
    Journal of inherited metabolic disease, 1990, Volume: 13, Issue:5

    Topics: Ammonia; Attention Deficit Disorder with Hyperactivity; Child, Preschool; Citrulline; Haloperidol; H

1990
Does haloperidol block methylphenidate?
    Journal of the American Academy of Child and Adolescent Psychiatry, 1989, Volume: 28, Issue:5

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Drug Therapy, Combination; Haloperidol; Humans

1989
Gilles de la Tourette's syndrome: tics and central nervous system stimulants in twins and nontwins.
    Neurology, 1986, Volume: 36, Issue:2

    Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulan

1986
Neuroleptic-induced tics in two hyperactive children.
    The American journal of psychiatry, 1986, Volume: 143, Issue:9

    Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Halop

1986
[The treatment of children with Gilles de la Tourette's syndrome].
    Tijdschrift voor kindergeneeskunde, 1987, Volume: 55, Issue:1

    Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Haloperidol;

1987
Tourette's syndrome in Monroe County school children.
    Neurology, 1988, Volume: 38, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior; Child; Child, Preschool; Clonid

1988