gossypol and Nausea studies

Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

Excerpt	Relevance	Reference
"Gossypol plasma levels were measured (n = 8) and the modulation of the retinoblastoma (Rb) gene protein and Cyclin D1 was assessed by serial biopsies (n = 4)."	6.70	Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial. ( Bacotti, D; Bloch, R; Borgen, P; Gollub, M; Hudis, C; Ligueros, M; Moasser, MM; Norton, L; Reidenberg, MM; Seidman, AD; Sklarin, N; Sonenberg, M; Van Poznak, C; Van Zee, K; Yao, TJ, 2001)
"Gossypol plasma levels were measured (n = 8) and the modulation of the retinoblastoma (Rb) gene protein and Cyclin D1 was assessed by serial biopsies (n = 4)."	2.70	Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial. ( Bacotti, D; Bloch, R; Borgen, P; Gollub, M; Hudis, C; Ligueros, M; Moasser, MM; Norton, L; Reidenberg, MM; Seidman, AD; Sklarin, N; Sonenberg, M; Van Poznak, C; Van Zee, K; Yao, TJ, 2001)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

gossypol and Nausea

Research Excerpts

Research

Studies (1)

Authors

Trials

Authors	Studies
Van Poznak, C	1
Seidman, AD	1
Reidenberg, MM	1
Moasser, MM	1
Sklarin, N	1
Van Zee, K	1
Borgen, P	1
Gollub, M	1
Bacotti, D	1
Yao, TJ	1
Bloch, R	1
Ligueros, M	1
Sonenberg, M	1
Norton, L	1
Hudis, C	1