Page last updated: 2024-10-18

glycine and Colitis

glycine has been researched along with Colitis in 20 studies

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
" Glycine supplementation is reported to reduce inflammatory responses in experimental colitis."8.02Glycine Attenuates Citrobacter rodentium-Induced Colitis by Regulating ATF6-Mediated Endoplasmic Reticulum Stress in Mice. ( Dai, Z; Jia, H; Jiang, D; Jin, Y; Kim, IH; Ren, F; Wu, Z; Yang, Y; Zhang, J; Zhang, Y, 2021)
" Here, we evaluated the anti-inflammatory Trimethylglycine and the Signal transducer and activator of transcription (STAT6) inhibitor AS1517499, as possible adjuvants to 5-FU in already established cancers, using a model of colitis-associated colon cancer (CAC)."7.96Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis. ( Beristain-Terrazas, DL; Callejas, BE; Chirino, YI; Delgado-Buenrostro, NL; García-Castillo, V; Gutierrez-Cirlos, EB; León-Cabrera, SA; Mendoza-Rodríguez, MG; Meraz-Ríos, MA; Pérez-Plasencia, C; Rodríguez-Sosa, M; Sánchez-Barrera, CÁ; Terrazas, LI; Vaca-Paniagua, F, 2020)
" The aim of the present study is to test the hypothesis that hydroxyproline (Hyp), an amino acid with an antioxidative property, attenuates dextran sulfate sodium (DSS)-induced colitis in mice."7.88Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-κB Signaling and Oxidative Stress. ( Dai, Z; Ji, Y; Ma, X; Sun, S; Tso, P; Wu, G; Wu, Z; Yang, Y, 2018)
"In this study, the effect of dietary glycine on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid (TNBS) and dextran sulfate sodium (DSS) in the rat was evaluated."7.72Dietary glycine prevents chemical-induced experimental colitis in the rat. ( Enomoto, N; Hirose, M; Ikejima, K; Sato, N; Takei, Y; Tsune, I; Yoshikawa, M, 2003)
"The efficacy of the leukocyte recruitment inhibitor, N-[9H-2,7-dimethylfluoren-9-ylmethoxy)carbonyl]-L-leucine (NPC 15669) was compared with drugs used to treat inflammatory bowel diseases in a rat model, acetic acid-induced colitis."7.68NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. ( Burch, RM; Lowe, VC; Muhlhauser, RO; Noronha-Blob, L, 1993)
"Acute colitis was induced using 8% DSS in male BALB/c mice."5.37Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice. ( Handa, O; Hirata, I; Ichikawa, H; Mizushima, K; Naito, Y; Omatsu, T; Suzuki, T; Takagi, T; Ueda, H; Yoshikawa, T, 2011)
" Glycine supplementation is reported to reduce inflammatory responses in experimental colitis."4.02Glycine Attenuates Citrobacter rodentium-Induced Colitis by Regulating ATF6-Mediated Endoplasmic Reticulum Stress in Mice. ( Dai, Z; Jia, H; Jiang, D; Jin, Y; Kim, IH; Ren, F; Wu, Z; Yang, Y; Zhang, J; Zhang, Y, 2021)
" Here, we evaluated the anti-inflammatory Trimethylglycine and the Signal transducer and activator of transcription (STAT6) inhibitor AS1517499, as possible adjuvants to 5-FU in already established cancers, using a model of colitis-associated colon cancer (CAC)."3.96Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis. ( Beristain-Terrazas, DL; Callejas, BE; Chirino, YI; Delgado-Buenrostro, NL; García-Castillo, V; Gutierrez-Cirlos, EB; León-Cabrera, SA; Mendoza-Rodríguez, MG; Meraz-Ríos, MA; Pérez-Plasencia, C; Rodríguez-Sosa, M; Sánchez-Barrera, CÁ; Terrazas, LI; Vaca-Paniagua, F, 2020)
" The aim of the present study is to test the hypothesis that hydroxyproline (Hyp), an amino acid with an antioxidative property, attenuates dextran sulfate sodium (DSS)-induced colitis in mice."3.88Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-κB Signaling and Oxidative Stress. ( Dai, Z; Ji, Y; Ma, X; Sun, S; Tso, P; Wu, G; Wu, Z; Yang, Y, 2018)
" Colonic delivery of celecoxib elicits anticolitic effects in a trinitrobenzene sulfonic acid-induced rat colitis model."3.81Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-κB, an anti-inflammatory target. ( Jeong, S; Jung, Y; Kim, MS; Kim, W; Lee, S; Lee, Y; Moon, HR; Nam, J; Yoo, JW, 2015)
" In vivo healing potential of KET-GLY was evaluated in acetic acid-induced experimental colitis model."3.75Optimized prodrug approach: a means for achieving enhanced anti-inflammatory potential in experimentally induced colitis. ( Dabas, S; Pathak, K; Philip, AK, 2009)
" In acetic acid-induced colitis in the rat, levels of malondialdehyde were found to be more markedly reduced with MED15 than with 5-aminosalicylic acid."3.72Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. ( Belogi, L; Bettelli, E; Mezzadri, CM; Tubaro, E, 2003)
"In this study, the effect of dietary glycine on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid (TNBS) and dextran sulfate sodium (DSS) in the rat was evaluated."3.72Dietary glycine prevents chemical-induced experimental colitis in the rat. ( Enomoto, N; Hirose, M; Ikejima, K; Sato, N; Takei, Y; Tsune, I; Yoshikawa, M, 2003)
"The efficacy of the leukocyte recruitment inhibitor, N-[9H-2,7-dimethylfluoren-9-ylmethoxy)carbonyl]-L-leucine (NPC 15669) was compared with drugs used to treat inflammatory bowel diseases in a rat model, acetic acid-induced colitis."3.68NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. ( Burch, RM; Lowe, VC; Muhlhauser, RO; Noronha-Blob, L, 1993)
"Acute colitis was induced in BALB/c mice by administration of dextran sulfate sodium (DSS) in drinking water for 7 days."1.40Neutrophil elastase inhibitor suppresses IL-17 based inflammation of murine experimental colitis. ( Katakura, K; Ohira, H; Shioya, Y, 2014)
"Acute colitis was induced using 8% DSS in male BALB/c mice."1.37Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice. ( Handa, O; Hirata, I; Ichikawa, H; Mizushima, K; Naito, Y; Omatsu, T; Suzuki, T; Takagi, T; Ueda, H; Yoshikawa, T, 2011)
"Acute colitis was induced in mice by administration of 1."1.33Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis. ( Chinen, H; Hibi, T; Hisamatsu, T; Inoue, N; Iwao, Y; Kamada, N; Matsuoka, K; Morohoshi, Y; Ogata, H; Okamoto, S; Sato, T; Takaishi, H, 2006)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's1 (5.00)18.2507
2000's4 (20.00)29.6817
2010's7 (35.00)24.3611
2020's6 (30.00)2.80

Authors

AuthorsStudies
Gan, Z1
Zhang, M1
Xie, D1
Wu, X2
Hong, C1
Fu, J1
Fan, L1
Wang, S1
Han, S1
Morozova, MV1
Borisova, MA1
Snytnikova, OA1
Achasova, KM1
Litvinova, EA1
Tsentalovich, YP1
Kozhevnikova, EN1
Rahmani, F1
Asgharzadeh, F1
Avan, A1
Barneh, F1
Parizadeh, MR1
Ferns, GA1
Ryzhikov, M1
Ahmadian, MR1
Giovannetti, E1
Jafari, M1
Khazaei, M1
Hassanian, SM1
Mendoza-Rodríguez, MG1
Sánchez-Barrera, CÁ1
Callejas, BE1
García-Castillo, V1
Beristain-Terrazas, DL1
Delgado-Buenrostro, NL1
Chirino, YI1
León-Cabrera, SA1
Rodríguez-Sosa, M1
Gutierrez-Cirlos, EB1
Pérez-Plasencia, C1
Vaca-Paniagua, F1
Meraz-Ríos, MA1
Terrazas, LI1
Zheng, Y1
Ma, J1
Yin, J1
Chen, S1
Zhang, Y1
Jiang, D1
Jin, Y1
Jia, H1
Yang, Y2
Kim, IH1
Dai, Z2
Zhang, J1
Ren, F1
Wu, Z2
Ji, Y1
Sun, S1
Ma, X1
Tso, P1
Wu, G1
Shioya, Y1
Katakura, K1
Ohira, H1
Lee, S1
Lee, Y1
Kim, W1
Nam, J1
Jeong, S1
Yoo, JW1
Kim, MS1
Moon, HR1
Jung, Y1
Philip, AK1
Dabas, S1
Pathak, K2
McCole, DF1
Hirata, I1
Naito, Y1
Takagi, T1
Mizushima, K1
Suzuki, T1
Omatsu, T1
Handa, O1
Ichikawa, H1
Ueda, H1
Yoshikawa, T1
Hart, ML1
Grenz, A1
Gorzolla, IC1
Schittenhelm, J1
Dalton, JH1
Eltzschig, HK1
Mishra, A1
Agrawal, S1
Tubaro, E1
Belogi, L1
Mezzadri, CM1
Bettelli, E1
Tsune, I1
Ikejima, K1
Hirose, M1
Yoshikawa, M1
Enomoto, N1
Takei, Y1
Sato, N1
Morohoshi, Y1
Matsuoka, K1
Chinen, H1
Kamada, N1
Sato, T1
Hisamatsu, T1
Okamoto, S1
Inoue, N1
Takaishi, H1
Ogata, H1
Iwao, Y1
Hibi, T1
Noronha-Blob, L1
Lowe, VC1
Muhlhauser, RO1
Burch, RM1
Smagin, VG1
Asafov, GB1
Ekisenina, NI1
Ivanova, LM1
Lumel'skiĭ, VIa1
Pedersen, L1
Arnfred, T1
Thaysen, EH1

Reviews

1 review available for glycine and Colitis

ArticleYear
Glycinergic Signaling in Macrophages and Its Application in Macrophage-Associated Diseases.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Colitis; Glycine; Humans; Macrophages; Metabolic Diseases; MicroRNAs; Neoplasms; Reperfusio

2021

Other Studies

19 other studies available for glycine and Colitis

ArticleYear
Colitis-associated intestinal microbiota regulates brain glycine and host behavior in mice.
    Scientific reports, 2022, 09-29, Volume: 12, Issue:1

    Topics: Animals; Brain; Choline; Colitis; Fabaceae; Female; Gastrointestinal Microbiome; Glycine; Inflammati

2022
Rigosertib potently protects against colitis-associated intestinal fibrosis and inflammation by regulating PI3K/AKT and NF-κB signaling pathways.
    Life sciences, 2020, May-15, Volume: 249

    Topics: Animals; Antineoplastic Agents; Colitis; Enzyme Inhibitors; Fibrosis; Glycine; Male; Mice; Mice, Inb

2020
Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis.
    International journal of molecular sciences, 2020, Mar-20, Volume: 21, Issue:6

    Topics: Adjuvants, Pharmaceutic; Animals; Apoptosis; beta Catenin; Cadherins; Carcinogenesis; Cell Adhesion

2020
The Effects of Dietary Glycine on the Acetic Acid-Induced Mouse Model of Colitis.
    Mediators of inflammation, 2020, Volume: 2020

    Topics: Acetic Acid; Animals; Clostridiales; Colitis; Disease Models, Animal; Glycine; Interleukin-10; Inter

2020
Glycine Attenuates Citrobacter rodentium-Induced Colitis by Regulating ATF6-Mediated Endoplasmic Reticulum Stress in Mice.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:15

    Topics: Activating Transcription Factor 6; Animals; Antimicrobial Peptides; Cell Death; Citrobacter rodentiu

2021
Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-κB Signaling and Oxidative Stress.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:21

    Topics: Animals; Apoptosis; Colitis; Dextran Sulfate; Disease Models, Animal; Glycine; Hydroxyproline; Inter

2018
Neutrophil elastase inhibitor suppresses IL-17 based inflammation of murine experimental colitis.
    Fukushima journal of medical science, 2014, Volume: 60, Issue:1

    Topics: Animals; Chemokines; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Gly

2014
Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-κB, an anti-inflammatory target.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Anti-Inflammatory Agents; Celecoxib; Cell Line; Colitis; Colon; Drug Delivery Systems; Drug

2015
Optimized prodrug approach: a means for achieving enhanced anti-inflammatory potential in experimentally induced colitis.
    Journal of drug targeting, 2009, Volume: 17, Issue:3

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Glycine; Ketoprofen; Prodrug

2009
The epithelial glycine transporter GLYT1: protecting the gut from inflammation.
    The Journal of physiology, 2010, Apr-01, Volume: 588, Issue:Pt 7

    Topics: Colitis; Cytoprotection; Glutathione; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; I

2010
Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:5

    Topics: Alkynes; Animals; Colitis; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dextran Sulfate;

2011
Hypoxia-inducible factor-1α-dependent protection from intestinal ischemia/reperfusion injury involves ecto-5'-nucleotidase (CD73) and the A2B adenosine receptor.
    Journal of immunology (Baltimore, Md. : 1950), 2011, Apr-01, Volume: 186, Issue:7

    Topics: 5'-Nucleotidase; Amino Acids, Dicarboxylic; Animals; Colitis; Glycine; Hypoxia-Inducible Factor 1, a

2011
Naproxen glycine conjugate-synthesis, pharmaceutical preformulation and pharmacodynamic evaluation.
    Drug delivery, 2012, Volume: 19, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Colitis; Colon; Drug Delivery Systems;

2012
Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon;

2003
Dietary glycine prevents chemical-induced experimental colitis in the rat.
    Gastroenterology, 2003, Volume: 125, Issue:3

    Topics: Animals; Cells, Cultured; Chemokine CXCL2; Chemokines; Chemokines, CXC; Colitis; Colon; Cytokines; G

2003
Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.
    Journal of gastroenterology, 2006, Volume: 41, Issue:4

    Topics: Adult; Animals; Biomarkers; Cells, Cultured; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease

2006
NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats.
    Gastroenterology, 1993, Volume: 104, Issue:4

    Topics: Acetates; Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capil

1993
[Amino acid levels in the blood serum of patients with chronic colitis].
    Terapevticheskii arkhiv, 1974, Volume: 46, Issue:4

    Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline;

1974
Rapid screening of increased bile acid deconjugation and bile acid malabsorption by means of the glycine-l-(14C) cholylglycine assay.
    Scandinavian journal of gastroenterology, 1973, Volume: 8, Issue:7

    Topics: Achlorhydria; Adult; Aged; Bile Acids and Salts; Carbon Radioisotopes; Chronic Disease; Colitis; Cro

1973