glycine and Ataxia
glycine has been researched along with Ataxia in 12 studies
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results indicate that pretreatment with Parawixin 10 prevents the onset of seizures induced with kainic acid, N-methyl-D-aspartate, and pentylenetetrazole in a dose-response manner." | 3.77 | Neurobiological activity of Parawixin 10, a novel anticonvulsant compound isolated from Parawixia bistriata spider venom (Araneidae: Araneae). ( Beleboni, RO; Coutinho-Netto, J; Cunha, AO; dos Santos, WF; Fachim, HA; Gobbo-Neto, L; Lopes, NP; Pereira, AC, 2011) |
| " The contents of taurine, aspartate, glutamate, glycine, and gamma-aminobutyric acid were determined in tissue and crude synaptosomal (P2) fraction of cerebellum, cerebral cortex, and spinal cord of methylmercury-treated mice with or without ataxia." | 3.67 | Alteration of putative amino acid levels and morphological findings in neural tissues of methylmercury-intoxicated mice. ( Fujisaki, T; Hirayama, K; Inouye, M, 1985) |
| "Familial hemiplegic migraine is an episodic neurological disorder characterized by transient sensory and motor symptoms and signs." | 1.56 | Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway. ( Bice, AR; Bonni, A; Brier, LM; Bumstead, JR; Chen, X; Crowley, JR; Culver, JP; Dikranian, K; Haigis, MC; Ippolito, JE; Oldenborg, A; Papouin, T; Rensing, NR; Ringel, AE; Shin, H; Smith, SE; Wong, M; Zhao, G, 2020) |
| " The pharmacokinetics of the active compounds was studied in dogs, which is a common animal model for a comparative crossover pharmacokinetic studies." | 1.30 | Pharmacokinetic analysis and anticonvulsant activity of glycine and glycinamide derivatives. ( Bialer, M; Dagan, A; Sussan, S, 1999) |
Research
Studies (12)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Wright, SE | 1 |
| Rodriguez, CM | 1 |
| Monroe, J | 1 |
| Xing, J | 1 |
| Krans, A | 1 |
| Flores, BN | 1 |
| Barsur, V | 1 |
| Ivanova, MI | 1 |
| Koutmou, KS | 1 |
| Barmada, SJ | 1 |
| Todd, PK | 1 |
| Smith, SE | 1 |
| Chen, X | 1 |
| Brier, LM | 1 |
| Bumstead, JR | 1 |
| Rensing, NR | 1 |
| Ringel, AE | 1 |
| Shin, H | 1 |
| Oldenborg, A | 1 |
| Crowley, JR | 1 |
| Bice, AR | 1 |
| Dikranian, K | 1 |
| Ippolito, JE | 1 |
| Haigis, MC | 1 |
| Papouin, T | 1 |
| Zhao, G | 1 |
| Wong, M | 1 |
| Culver, JP | 1 |
| Bonni, A | 1 |
| Fachim, HA | 1 |
| Cunha, AO | 1 |
| Pereira, AC | 1 |
| Beleboni, RO | 1 |
| Gobbo-Neto, L | 1 |
| Lopes, NP | 1 |
| Coutinho-Netto, J | 1 |
| dos Santos, WF | 1 |
| O'Shea, SM | 1 |
| Becker, L | 1 |
| Weiher, H | 1 |
| Betz, H | 1 |
| Laube, B | 1 |
| Rabier, D | 1 |
| Diry, C | 1 |
| Rotig, A | 1 |
| Rustin, P | 1 |
| Heron, B | 1 |
| Bardet, J | 1 |
| Parvy, P | 1 |
| Ponsot, G | 1 |
| Marsac, C | 1 |
| Saudubray, JM | 1 |
| Munnich, A | 1 |
| Kamoun, P | 1 |
| Sussan, S | 1 |
| Dagan, A | 1 |
| Bialer, M | 1 |
| Snell, LD | 1 |
| Claffey, DJ | 1 |
| Ruth, JA | 1 |
| Valenzuela, CF | 1 |
| Cardoso, R | 1 |
| Wang, Z | 1 |
| Levinson, SR | 1 |
| Sather, WA | 1 |
| Williamson, AV | 1 |
| Ingersoll, NC | 1 |
| Ovchinnikova, L | 1 |
| Bhave, SV | 1 |
| Hoffman, PL | 1 |
| Tabakoff, B | 1 |
| Grüsser-Cornehls, U | 1 |
| Bäurle, J | 1 |
| Bank, WJ | 1 |
| Pizer, L | 1 |
| Pfendner, W | 1 |
| Sorrels, TL | 1 |
| Bostock, E | 1 |
| Hirayama, K | 1 |
| Inouye, M | 1 |
| Fujisaki, T | 1 |
| Breglia, RJ | 1 |
| Ward, CO | 1 |
| Jarowski, CI | 1 |
Reviews
1 review available for glycine and Ataxia
| Article | Year |
|---|---|
Mutant mice as a model for cerebellar ataxia.
Topics: Animals; Ataxia; Cerebellar Ataxia; Cerebellum; Disease Models, Animal; gamma-Aminobutyric Acid; Gly | 2001 |
Other Studies
11 other studies available for glycine and Ataxia
| Article | Year |
|---|---|
CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins.
Topics: Arginine; Ataxia; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glycine; Humans; Neurode | 2022 |
Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway.
Topics: Animals; Astrocytes; Ataxia; Brain; Disease Models, Animal; Electroencephalography; Female; Function | 2020 |
Neurobiological activity of Parawixin 10, a novel anticonvulsant compound isolated from Parawixia bistriata spider venom (Araneidae: Araneae).
Topics: Analysis of Variance; Animals; Anticonvulsants; Ataxia; Cerebral Cortex; Chromatography, High Pressu | 2011 |
Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.
Topics: Anesthetics, Intravenous; Animals; Ataxia; Behavior, Animal; Cells, Cultured; Dose-Response Relation | 2004 |
Persistent hypocitrullinaemia as a marker for mtDNA NARP T 8993 G mutation?
Topics: Abnormalities, Multiple; Ataxia; Biomarkers; Child, Preschool; Citrulline; DNA, Mitochondrial; Femal | 1998 |
Pharmacokinetic analysis and anticonvulsant activity of glycine and glycinamide derivatives.
Topics: Animals; Anticonvulsants; Ataxia; Chromatography, High Pressure Liquid; Convulsants; Cross-Over Stud | 1999 |
Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: biochemical, electrophysiological, and behavioral characterization.
Topics: Animals; Anti-Anxiety Agents; Ataxia; Behavior, Animal; Binding Sites; Binding, Competitive; Cells, | 2000 |
Glycine metabolism and spinal cord disorders.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Animals; Ataxia; Cats; Cells, Cultured; Chi | 1978 |
Induction of feeding by 7-chlorokynurenic acid, a strychnine-insensitive glycine binding site antagonist.
Topics: Analysis of Variance; Animals; Ataxia; Dose-Response Relationship, Drug; Feeding Behavior; Glycine; | 1992 |
Alteration of putative amino acid levels and morphological findings in neural tissues of methylmercury-intoxicated mice.
Topics: Amino Acids; Animals; Ataxia; Central Nervous System; Cerebellum; Cerebral Cortex; gamma-Aminobutyri | 1985 |
Effect of selected amino acids on ethanol toxicity in rats.
Topics: Administration, Oral; Alcoholic Intoxication; Amino Acids; Animals; Arginine; Ataxia; Central Nervou | 1973 |