Page last updated: 2024-10-18

glycine and Acidosis

glycine has been researched along with Acidosis in 94 studies

Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.

Research Excerpts

ExcerptRelevanceReference
"Metaflumizone shares a similar chemical structure to indoxacarb, which is known to be a cause of methemoglobinemia."7.80Methemoglobinemia associated with metaflumizone poisoning. ( Choi, KH; Oh, JS, 2014)
" Either glycine (2 mM) or extracellular fluid acidosis (pH 7."7.68Acute phosphate depletion and in vitro rat proximal tubule injury: protection by glycine and acidosis. ( Almeida, AR; Bunnachak, D; Burke, TJ; Chaimovitz, C; Hammond, WS; Schrier, RW; Wetzels, JF, 1992)
"Strychnine poisoning results in a predictable and treatable sequence of events involving blockade of the inhibitory neurotransmitter, extensor muscle spasms, seizures, and respiratory paralysis."7.66Strychnine poisoning. Recovery from profound lactic acidosis, hyperthermia, and rhabdomyolysis. ( Boyd, RE; Brennan, PT; Deng, JF; Rochester, DF; Spyker, DA, 1983)
"Ingestion of glyphosate-surfactant herbicides (GlySH) can result in acute kidney injury, electrolyte abnormalities, acidosis, cardiovascular collapse, and death."3.80Hemodialysis clearance of glyphosate following a life-threatening ingestion of glyphosate-surfactant herbicide. ( Allan, MJ; Garlich, FM; Goldfarb, DS; Goldman, M; Goldstein, DA; Hoffman, RS; Nelson, LS; Pepe, J, 2014)
"Metaflumizone shares a similar chemical structure to indoxacarb, which is known to be a cause of methemoglobinemia."3.80Methemoglobinemia associated with metaflumizone poisoning. ( Choi, KH; Oh, JS, 2014)
" Biochemically, beta-ketothiolase deficiency is characterized by intermittent ketoacidosis and urinary excretion of 2-methyl-acetoacetate (MAA), 2-methyl-3-hydroxybutyrate (MHB) and tiglylglycine (TG), whereas in MHBD deficiency only MHB and tiglylglycine accumulate."3.73Inhibition of energy metabolism by 2-methylacetoacetate and 2-methyl-3-hydroxybutyrate in cerebral cortex of developing rats. ( da C Ferreira, G; Dalcin, KB; de Assis, DR; Filho, CS; Latini, A; Leipnitz, G; Maria, RC; Perry, ML; Ribeiro, CA; Rosa, RB; Schuck, PF; Wajner, M; Wannmacher, CM; Wyse, AT, 2005)
" Either glycine (2 mM) or extracellular fluid acidosis (pH 7."3.68Acute phosphate depletion and in vitro rat proximal tubule injury: protection by glycine and acidosis. ( Almeida, AR; Bunnachak, D; Burke, TJ; Chaimovitz, C; Hammond, WS; Schrier, RW; Wetzels, JF, 1992)
"A child with a history of episodes of metabolic acidosis was found to excrete 3-hydroxyisovaleric acid and 3-methylcrotonylglycine."3.66A combined defect of three mitochondrial carboxylases presenting as biotin-responsive 3-methylcrotonyl glycinuria and 3-hydroxyisovaleric aciduria. ( Bartlett, K; Leonard, JV; Ng, H, 1980)
"Strychnine poisoning results in a predictable and treatable sequence of events involving blockade of the inhibitory neurotransmitter, extensor muscle spasms, seizures, and respiratory paralysis."3.66Strychnine poisoning. Recovery from profound lactic acidosis, hyperthermia, and rhabdomyolysis. ( Boyd, RE; Brennan, PT; Deng, JF; Rochester, DF; Spyker, DA, 1983)
"The tendency towards metabolic acidosis developing during simple infections lead to the detection of hyperglycinemia which was shown to be caused by the rare inborn error of metabolism, which was shown to be a methylmalonic acidemia, in identical twins."3.66[Vitamin-B12-dependent methylmalonic acidemia in twins]. ( Hansen, HG; Heuer, R; Karsten, J; Kneer, J; Wulff, UC, 1983)
" The patients suffered from distinct variants of maple syrup urine disease, propionic acidaemia, methylmalonic acidaemia, lactic acidosis and hyperglycinuria."3.66[Human fibroblast bank for studying amino acid disorders and organic acidemias]. ( del Valle, JA; Merinero, B; Pérez-Cerdá, C; Ugarte, M, 1982)
"A patient presenting with severe metabolic acidosis accompanied by hyperglycinemia, hyperuricemia, hypoglycemia and hypertammonemia is described."3.66Methylmalonic acidemia. ( Akaboshi, I; Hattori, S; Matsuda, I; Nagata, N; Oka, Y; Shinozuka, S; Terashima, T; Yamamoto, J, 1978)
"Chronic low-grade metabolic acidosis is now a common phenomenon in the Western world."1.91Dietary Acid Load Correlates with Serum Amino Acid Concentrations after a Four-Week Intervention with Vegan vs. Meat-Rich Diets: A Secondary Data Analysis. ( Hannibal, L; Herter, J; Huber, R; Lederer, AK; Ronco, AL; Storz, MA, 2023)
"Carnitine conjugates were however detected."1.29The detection of 3-methylglutarylcarnitine and a new dicarboxylic conjugate, 3-methylglutaconylcarnitine, in 3-methylglutaconic aciduria. ( de Wet, WJ; Erasmus, E; Gibson, KM; Jooste, S; Mienie, LJ, 1994)
"[15N]Glycine was infused into fed, fasted or acidotic humans."1.26[15N]Glycine metabolism in normal man: the metabolic alpha-amino-nitrogen pool. ( Golden, MH; Jackson, AA, 1980)
"However, ketonuria was not a consistent part of his clinical picture, and he had at least two episodes of acute overwhelming illness, the latter one fatal, in which ketones were never found in the urine."1.25Hyperglycinemia and propionyl coA carboxylase deficiency and episodic severe illness without consistent ketosis. ( Ando, T; Kilroy, A; Nyhan, WL; Sweetman, L; Wadlington, WB, 1975)

Research

Studies (94)

TimeframeStudies, this research(%)All Research%
pre-199068 (72.34)18.7374
1990's11 (11.70)18.2507
2000's3 (3.19)29.6817
2010's10 (10.64)24.3611
2020's2 (2.13)2.80

Authors

AuthorsStudies
Mpabanzi, L1
Wainwright, J1
Boonen, B1
van Eijk, H1
Dhar, D1
Karssemeijer, E1
Dejong, CHC1
Jalan, R1
Schwartz, JM1
Olde Damink, SWM1
Soons, Z1
Herter, J1
Lederer, AK1
Ronco, AL1
Hannibal, L1
Huber, R1
Storz, MA1
Bancel, LP1
Germain, N1
Guemann, AS1
Joncquel Chevalier Curt, M1
Dessein, AF1
Jović-Stošić, J1
Putić, V1
Perković-Vukčević, N1
Babić, G1
Đorđević, S1
Šegrt, Z1
Chen, N1
Hao, C1
Peng, X1
Lin, H1
Yin, A1
Hao, L1
Tao, Y1
Liang, X1
Liu, Z1
Xing, C1
Chen, J1
Luo, L1
Zuo, L1
Liao, Y1
Liu, BC1
Leong, R1
Wang, C1
Liu, C1
Neff, T1
Szczech, L1
Yu, KP1
Santarelli, F1
Cassanello, M1
Enea, A1
Poma, F1
D'Onofrio, V1
Guala, G1
Garrone, G1
Puccinelli, P1
Caruso, U2
Porta, F1
Spada, M1
Akira, K1
Hichiya, H1
Morita, M1
Shimizu, A1
Mitome, H1
Garlich, FM1
Goldman, M1
Pepe, J1
Nelson, LS1
Allan, MJ1
Goldstein, DA1
Goldfarb, DS1
Hoffman, RS1
Oh, JS1
Choi, KH1
Malhotra, RC1
Ghia, DK1
Cordato, DJ1
Beran, RG1
Jing, L1
Chu, XP1
Jiang, YQ1
Collier, DM1
Wang, B1
Jiang, Q1
Snyder, PM1
Zha, XM1
Zouaoui, K1
Dulaurent, S1
Gaulier, JM1
Moesch, C1
Lachâtre, G1
NYHAN, WL10
CHISOLM, JJ1
EDWARDS, RO1
CHILDS, B1
CRISTOFORI, FC1
DUNCAN, GG1
PITTS, RF3
PILKINGTON, LA2
DEHAAS, JC1
GEROK, W1
PABST, K1
WELCH, J1
SAUER, F1
Stella, J1
Ryan, M1
Rosa, RB1
Schuck, PF1
de Assis, DR1
Latini, A1
Dalcin, KB1
Ribeiro, CA1
da C Ferreira, G1
Maria, RC1
Leipnitz, G1
Perry, ML1
Filho, CS1
Wyse, AT1
Wannmacher, CM1
Wajner, M1
Cohen, MV1
Yang, XM1
Downey, JM1
Soriano, JR1
Taitz, LS1
Finberg, L1
Edelmann, CM1
Bennett, MJ1
Littlewood, JM1
MacDonald, A1
Pollitt, RJ1
Thompson, J1
Schoos-Barbette, S1
Gerard, J1
Francotte, N1
Lambotte, C1
Bartlett, K1
Ng, H1
Leonard, JV2
Merinero, B2
DelValle, JA1
Jiménez, A1
Garcia, MJ1
Ugarte, M2
Solaguren, R1
López, O1
Condado, I1
Boyd, RE1
Brennan, PT1
Deng, JF1
Rochester, DF1
Spyker, DA1
Karsten, J1
Hansen, HG1
Heuer, R1
Wulff, UC1
Kneer, J1
Tizianello, A1
Deferrari, G1
Garibotto, G1
Robaudo, C1
Acquarone, N1
Ghiggeri, GM1
Hayasaka, K1
Narisawa, K1
Satoh, T1
Tateda, H1
Metoki, K1
Tada, K2
Hiraga, K1
Aoki, T1
Kawakami, T1
Akamatsu, H1
Matsuo, N1
del Valle, JA1
Pérez-Cerdá, C1
Schutgens, RB1
Middleton, B2
vd Blij, JF1
Oorthuys, JW1
Veder, HA1
Vulsma, T1
Tegelaers, WH1
Jackson, AA1
Golden, MH1
Pillière, F1
Maigret, P1
Garnier, R1
Harry, P1
Baud, F1
Efthymiou, ML1
Weinberg, JM2
Venkatachalam, MA2
Goldberg, H1
Roeser, NF2
Davis, JA2
Jooste, S1
Erasmus, E1
Mienie, LJ1
de Wet, WJ1
Gibson, KM1
Ito, T1
Kidouchi, K1
Sugiyama, N1
Kajita, M1
Chiba, T1
Niwa, T1
Wada, Y1
Fukao, T1
Kodama, A1
Aoyanagi, N1
Tsukino, R1
Uemura, S1
Song, XQ1
Watanebe, H1
Kuhara, T1
Matsumoto, I1
Orii, T1
Kondo, N1
Mályusz, M1
Rudolph, N1
Barth, A1
Gronow, G1
Mályusz, T1
van den Berg, H1
Boelkens, MT1
Hommes, FA3
Musil, J1
Matsuda, I1
Terashima, T1
Yamamoto, J1
Akaboshi, I1
Shinozuka, S1
Hattori, S1
Nagata, N1
Oka, Y1
Lehtonen, T1
Yudkoff, M1
Cohn, RM1
Puschak, R1
Rothman, R1
Segal, S1
O'Brien, WE1
Wadlington, WB1
Kilroy, A1
Ando, T7
Sweetman, L1
Rowley, BO1
Brothers, V1
Gerritsen, T3
Krieger, I1
Tanaka, K2
Dodelson de Kremer, R1
Depetris de Boldini, C1
Paschini de Capra, A1
Hliba, E1
Corbella, L1
Almeida, AR1
Wetzels, JF1
Bunnachak, D1
Burke, TJ1
Chaimovitz, C1
Hammond, WS1
Schrier, RW1
Pesce, F1
Cerone, R1
Romano, C1
Indo, Y1
Glassberg, R1
Yokota, I1
Seakins, JW1
Gompertz, D3
Draffan, GH1
Watts, JL1
Hull, D4
Eldjarn, L1
Jellum, E1
Stokke, O1
Hsia, YE3
Scully, KJ1
Rosenberg, LE2
Haworth, JC1
Ford, JD1
Storrs, CN1
Bau, DC1
Peters, TJ1
Hughes, EA1
Barnes, ND2
Balgobin, L1
Wei, EP1
Thames, MD2
Kontos, HA2
Patterson, JL1
Guibaud, P2
Frimpter, GW1
Host, WR1
Serlin, O1
Rush, BF1
Keating, JP2
Feigin, RD1
Tenenbaum, SM1
Hillman, RE2
Daum, RS1
Scriver, CR1
Mamer, OA1
Delvin, E1
Lamm, P1
Goldman, H1
Duran, M1
Ketting, D1
Wadman, SK1
Trijbels, JM1
Bakkeren, JA1
Waelkens, JJ1
Brandt, IK1
Clement, DH1
Provence, SA1
Bergman, EN1
Kaufman, CF1
Wolff, JE1
Williams, HH1
Rasmussen, K3
Cottom, D2
Donnell, G2
Wadlington, W1
Kilroy, AW1
Connor, JD1
Barnes, N1
Lombana, A1
Watlington, CO1
Jessee, F1
Centa, A1
Pedersen, VF1
De Groot, CJ2
Troelstra, JA1
Larbre, F1
Hartemann, E1
Collombel, C1
Guerrier, G1
Okken, A1
Ferdinand, W1
Gordon, RR1
Owen, G1
Christophe, J1
Winand, J1
Kutzner, R1
Hebbelinck, M1
Donnell, GN1
Rampini, S1
Vischer, D1
Curtius, HC1
Anders, PW1
Tancredi, F1
Frischknecht, W1
Prader, A1
Lilljeqvist, AC1
Campanacci, L1
Guarnieri, GF1
Siliprandi, N1
Fiaschi, E1
Gong, L1
Heiner, DC1
Bray, PF1
Lindblad, B1
Lindblad, BS1
Olin, P1
Svanberg, B1
Zetterström, R1
Broyer, M1
Berger, R1
Morrow, G1
Barness, LA1
Auerbach, VH1
DiGeorge, AM1
Rehberg, ML1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety of FG-4592 for Treatment of Anemia in Subjects With Chronic Kidney Disease Not on Dialysis[NCT02652819]Phase 3154 participants (Actual)Interventional2015-12-31Completed
A Randomized Controlled Trial to Evaluate the Safety and Efficacy of Roxadustat in Patients With Acute ST Elevation Myocardial Infarction[NCT04803864]Phase 2158 participants (Anticipated)Interventional2021-06-10Recruiting
Roxadustat Reduces the Incidence of Acute Kidney Injury After Coronary Artery Bypass Grafting: a Multicenter, Randomized, Double-blind, Placebo-controlled Study[NCT05010460]Phase 2318 participants (Anticipated)Interventional2021-09-30Recruiting
Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253]Phase 3400 participants (Anticipated)Interventional2015-05-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for glycine and Acidosis

ArticleYear
[ON THE PATHOPHYSIOLOGY AND CLINICAL MANIFESTATIONS OF DISORDERS OF RENAL TUBULAR PARTIAL FUNCTION].
    Munchener medizinische Wochenschrift (1950), 1965, Jan-08, Volume: 107

    Topics: Acidosis; Acidosis, Renal Tubular; Amino Acids; Cystinuria; Diabetes Insipidus; Glycine; Glycosuria;

1965
[Propionic acidemia. New concept of hyperglycinemia with ketosis].
    Pediatrie, 1972, Volume: 27, Issue:2

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Glycine; Humans; Propionates

1972
Aminoacidurias due to inherited disorders of metabolism. 2.
    The New England journal of medicine, 1973, Oct-25, Volume: 289, Issue:17

    Topics: Acidosis; Alanine; Amino Acid Metabolism, Inborn Errors; Arginase; Arginine; Carbamates; Citrulline;

1973

Trials

2 trials available for glycine and Acidosis

ArticleYear
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
A comparative study of Kystosol and glycine as irrigating solutions during transurethral prostatic resection.
    Annales chirurgiae et gynaecologiae, 1978, Volume: 67, Issue:4

    Topics: Acetates; Acidosis; Drug Combinations; Drug Evaluation; Glycine; Humans; Male; Prostatectomy; Prosta

1978

Other Studies

89 other studies available for glycine and Acidosis

ArticleYear
Fluxomics reveals cellular and molecular basis of increased renal ammoniagenesis.
    NPJ systems biology and applications, 2022, 12-20, Volume: 8, Issue:1

    Topics: Acidosis; Amino Acids; Ammonia; Animals; Glycine; Kidney; Rats

2022
Dietary Acid Load Correlates with Serum Amino Acid Concentrations after a Four-Week Intervention with Vegan vs. Meat-Rich Diets: A Secondary Data Analysis.
    Nutrients, 2023, Jun-28, Volume: 15, Issue:13

    Topics: Acidosis; Acids; Diet; Diet, Vegan; Glutamine; Glycine; Humans; Meat; Secondary Data Analysis; Vegan

2023
Abnormal Ketone Bodies in a 22-Month-Old Boy Presenting with Recurrent Vomiting and Metabolic Acidosis.
    Clinical chemistry, 2019, Volume: 65, Issue:11

    Topics: Acetoacetates; Acetyl-CoA C-Acyltransferase; Acidosis; Amino Acid Metabolism, Inborn Errors; Glycine

2019
Intravenous lipid emulsion in treatment of cardiocirculatory disturbances caused by glyphosate-surfactant herbicide poisoning.
    Vojnosanitetski pregled, 2016, Volume: 73, Issue:4

    Topics: Acidosis; Electrocardiography; Fat Emulsions, Intravenous; Glycine; Glyphosate; Herbicides; Humans;

2016
A neonatal case of 3-hydroxy-3-methylglutaric-coenzyme A lyase deficiency.
    Italian journal of pediatrics, 2013, May-24, Volume: 39

    Topics: Acetyl-CoA C-Acetyltransferase; Acidosis; Acute Disease; Amino Acid Metabolism, Inborn Errors; Gluta

2013
Metabonomic study on the biochemical response of spontaneously hypertensive rats to chronic taurine supplementation using (1)H NMR spectroscopic urinalysis.
    Journal of pharmaceutical and biomedical analysis, 2013, Volume: 85

    Topics: Acidosis; Animals; Blood Pressure; Citric Acid Cycle; Cresols; Dietary Supplements; Glycine; Magneti

2013
Hemodialysis clearance of glyphosate following a life-threatening ingestion of glyphosate-surfactant herbicide.
    Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:1

    Topics: Acidosis; Blood Chemical Analysis; Electrocardiography; Glycine; Glyphosate; Hemodynamics; Herbicide

2014
Methemoglobinemia associated with metaflumizone poisoning.
    Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:4

    Topics: Acidosis; Alcohol Drinking; Antidotes; Combined Modality Therapy; Glycine; Glyphosate; Humans; Insec

2014
Glyphosate-surfactant herbicide-induced reversible encephalopathy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:11

    Topics: Acidosis; Acute Disease; Aged; Coma; Glasgow Coma Scale; Glycine; Glyphosate; Herbicides; Humans; Ma

2010
N-glycosylation of acid-sensing ion channel 1a regulates its trafficking and acidosis-induced spine remodeling.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Mar-21, Volume: 32, Issue:12

    Topics: Acid Sensing Ion Channels; Acidosis; Analysis of Variance; Animals; Animals, Newborn; Asparagine; Bi

2012
Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication.
    Forensic science international, 2013, Mar-10, Volume: 226, Issue:1-3

    Topics: Accidents; Acidosis; Adult; Aged; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chro

2013
Idiopathic hyperglycinuria. III. Report of a second case.
    The Journal of pediatrics, 1963, Volume: 62

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Glycine; Proteins; Urolithiasis

1963
FURTHER OBSERVATIONS OF A PATIENT WITH HYPERGLYCINEMIA.
    Pediatrics, 1964, Volume: 33

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Blood; Child; Diet; Diet Therapy; Glycine; Humans; I

1964
URIC ACID EXCRETION IN OBESE SUBJECTS DURING PERIODS OF TOTAL FASTING.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Acidosis; Basal Metabolism; Blood Glucose; Fasting; Glycine; Humans; Obesity; Pennsylvania; Probenec

1964
N15 TRACER STUDIES ON THE ORIGIN OF URINARY AMMONIA IN THE ACIDOTIC DOG, WITH NOTES ON THE ENZYMATIC SYNTHESIS OF LABELED CLUTAMIC ACID AND GLUTAMINES.
    The Journal of clinical investigation, 1965, Volume: 44

    Topics: Acidosis; Amino Acids; Ammonia; Blood; Chromatography; Creatine; Creatinine; Dogs; Glutamates; Gluta

1965
RELATIONSHIP OF PNH3 OF TUBULAR CELLS TO RENAL PRODUCTION OF AMMONIA.
    The American journal of physiology, 1965, Volume: 208

    Topics: Acidosis; Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Body Fluids; Dog

1965
Acetoacetate and beta-hydroxy-beta-methyl glutaryl coenzyme A metabolism in normal and ketotic guinea pigs.
    Canadian journal of biochemistry and physiology, 1961, Volume: 39

    Topics: Acetoacetates; Acidosis; Acyl Coenzyme A; Coenzymes; Glycine; Guinea Pigs; Ketoses; Ketosis

1961
Glyphosate herbicide formulation: a potentially lethal ingestion.
    Emergency medicine Australasia : EMA, 2004, Volume: 16, Issue:3

    Topics: Acidosis; Administration, Oral; Adult; Aged; Drug Overdose; Emergency Medicine; Fatal Outcome; Glyci

2004
Inhibition of energy metabolism by 2-methylacetoacetate and 2-methyl-3-hydroxybutyrate in cerebral cortex of developing rats.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:4

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetates; Acetoacetates; Acetyl-CoA C-Acyltransferase; Acidosis; A

2005
The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis.
    Circulation, 2007, Apr-10, Volume: 115, Issue:14

    Topics: Acidosis; Alkaloids; Animals; Apoptosis; Benzophenanthridines; Buffers; Carbon Dioxide; Catheterizat

2007
Treatment of hyperglycinemia.
    American journal of diseases of children (1960), 1967, Volume: 113, Issue:1

    Topics: Acidosis; Agranulocytosis; Amino Acid Metabolism, Inborn Errors; Blood Platelet Disorders; Child; Ch

1967
Hyperglycinemia with ketoacidosis and leukopenia. Metabolic studies on the nature of the defect.
    Pediatrics, 1967, Volume: 39, Issue:6

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Diet Therapy; Dietary Proteins

1967
A case of beta-ketothiolase deficiency.
    Journal of inherited metabolic disease, 1983, Volume: 6, Issue:4

    Topics: Acetyl-CoA C-Acyltransferase; Acidosis; Acyltransferases; Dietary Proteins; Female; Glycine; Humans;

1983
A treatment of non-ketotic hyperglycinaemia.
    Journal of inherited metabolic disease, 1984, Volume: 7, Issue:4

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Combined Modality Therapy; Deoxych

1984
A combined defect of three mitochondrial carboxylases presenting as biotin-responsive 3-methylcrotonyl glycinuria and 3-hydroxyisovaleric aciduria.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Jan-15, Volume: 100, Issue:2

    Topics: Acidosis; Acyl Coenzyme A; Amino Acid Metabolism, Inborn Errors; Biotin; Butyrates; Carbon Dioxide;

1980
Late onset type of propionic acidaemia: case report and biochemical studies.
    Journal of inherited metabolic disease, 1981, Volume: 4, Issue:2

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carbon-Carbon Ligases; Female; Glycine; Humans; Hydr

1981
Strychnine poisoning. Recovery from profound lactic acidosis, hyperthermia, and rhabdomyolysis.
    The American journal of medicine, 1983, Volume: 74, Issue:3

    Topics: Acidosis; Adult; Body Temperature; Creatine Kinase; Female; Fever; Glycine; Humans; Hydrogen-Ion Con

1983
[Vitamin-B12-dependent methylmalonic acidemia in twins].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1983, Volume: 131, Issue:5

    Topics: Acidosis; Diseases in Twins; Glycine; Humans; Infant; Malonates; Metabolism, Inborn Errors; Methylma

1983
Renal ammoniagenesis in an early stage of metabolic acidosis in man.
    The Journal of clinical investigation, 1982, Volume: 69, Issue:1

    Topics: Acidosis; Adult; Amino Acids; Ammonia; Bicarbonates; Diuresis; Glutamine; Glycine; Humans; Kidney; M

1982
Glycine cleavage system in ketotic hyperglycinemia: a reduction of H-protein activity.
    Pediatric research, 1982, Volume: 16, Issue:1

    Topics: Acidosis; Amino Acid Oxidoreductases; Carrier Proteins; Female; Glycine; Glycine Decarboxylase Compl

1982
[Human fibroblast bank for studying amino acid disorders and organic acidemias].
    Revista espanola de fisiologia, 1982, Volume: 38 Suppl

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Cell Line; Cells, Cultured; Child; Child, Preschool;

1982
Beta-ketothiolase deficiency in a family confirmed by in vitro enzymatic assays in fibroblasts.
    European journal of pediatrics, 1982, Volume: 139, Issue:1

    Topics: Acetyl-CoA C-Acyltransferase; Acidosis; Acyltransferases; Adult; Child; Fibroblasts; Glycine; Humans

1982
[15N]Glycine metabolism in normal man: the metabolic alpha-amino-nitrogen pool.
    Clinical science (London, England : 1979), 1980, Volume: 58, Issue:6

    Topics: Acidosis; Adult; Alanine; Ammonia; Deamination; Fasting; Glutamates; Glycine; Humans; Male; Nitrogen

1980
[Intoxications by a weedkiller preparation containing glyphosate].
    Presse medicale (Paris, France : 1983), 1993, Mar-20, Volume: 22, Issue:10

    Topics: Acidosis; Acute Kidney Injury; Amylases; Burns, Chemical; Digestive System Diseases; Glycine; Glypho

1993
Modulation by Gly, Ca, and acidosis of injury-associated unesterified fatty acid accumulation in proximal tubule cells.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Acidosis; Animals; Antimycin A; Biological Transport; Calcium; Cell Hypoxia; Dose-Response Relations

1995
The detection of 3-methylglutarylcarnitine and a new dicarboxylic conjugate, 3-methylglutaconylcarnitine, in 3-methylglutaconic aciduria.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Oct-14, Volume: 230, Issue:1

    Topics: Acidosis; Carnitine; Chromatography, Gas; Female; Fibroblasts; Glutarates; Glycine; Humans; Hydro-Ly

1994
Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric analysis of glycine conjugates and urinary isovalerylglycine in isovaleric acidemia.
    Journal of chromatography. B, Biomedical applications, 1995, Aug-18, Volume: 670, Issue:2

    Topics: Acidosis; Administration, Oral; Carnitine; Child, Preschool; Chromatography, Liquid; Female; Glucuro

1995
Mild form of beta-ketothiolase deficiency (mitochondrial acetoacetyl-CoA thiolase deficiency) in two Japanese siblings: identification of detectable residual activity and cross-reactive material in EB-transformed lymphocytes.
    Clinical genetics, 1996, Volume: 50, Issue:4

    Topics: Acetyl-CoA C-Acyltransferase; Acidosis; Amino Acid Metabolism, Inborn Errors; Cell Line, Transformed

1996
Hippurate as a source of renal and hepatic ammoniagenesis in different species.
    Contributions to nephrology, 1997, Volume: 121

    Topics: Acidosis; Ammonia; Animals; Cats; Cattle; Glutamine; Glycine; Hippurates; Humans; Kidney; Kidney Tub

1997
A case of methylmalonic and propionic acidemia due to methulmalonyl-CoA carbonylmutase apoenzyme deficiency.
    Acta paediatrica Scandinavica, 1976, Volume: 65, Issue:1

    Topics: Acidosis; Amino Acids; Apoenzymes; Apoproteins; Glycine; Humans; Infant, Newborn; Isomerases; Male;

1976
Physiological characteristics of various experimental models for the study of disorders in purine metabolism.
    Advances in experimental medicine and biology, 1977, Volume: 76B

    Topics: Acidosis; Alkalosis; Allopurinol; Animals; Cholesterol; Disease Models, Animal; Diuresis; Fructose;

1977
Methylmalonic acidemia.
    European journal of pediatrics, 1978, Jul-03, Volume: 128, Issue:3

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Ammonia; Female; Glycine; Humans; Hypoglycemia; Infa

1978
Glycine therapy in isovaleric acidemia.
    The Journal of pediatrics, 1978, Volume: 92, Issue:5

    Topics: Acidosis; Administration, Oral; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Drug Adminis

1978
Inhibition of glycine synthase by branched-chain alpha-keto acids. A possible mechanism for abnormal glycine metabolism in ketotic hyperglycinemia.
    Archives of biochemistry and biophysics, 1978, Volume: 189, Issue:2

    Topics: Acidosis; Acyl Coenzyme A; Animals; Caproates; Glycine; Keto Acids; Ketosis; Liver; Male; Rats; Tran

1978
Hyperglycinemia and propionyl coA carboxylase deficiency and episodic severe illness without consistent ketosis.
    The Journal of pediatrics, 1975, Volume: 86, Issue:5

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Citrates; Coenzyme A; Creatinine; Croto

1975
The vitamin B12-deficient rat as a possible model of ketotic hyperglycinemia.
    Pediatric research, 1975, Volume: 9, Issue:10

    Topics: Acidosis; Animals; Biotin; Carbon Dioxide; Carboxy-Lyases; Glycine; Glycine Hydroxymethyltransferase

1975
Therapeutic effects of glycine in isovaleric acidemia.
    Pediatric research, 1976, Volume: 10, Issue:1

    Topics: Acidosis; Alkalies; Amino Acid Metabolism, Inborn Errors; Child; Female; Glycine; Humans; Inactivati

1976
[Phenotypic expression variation of isovaleric acidemia in Argentinian patients. A long term follow-up].
    Medicina, 1992, Volume: 52, Issue:2

    Topics: Acidosis; Brain; Child, Preschool; Chromatography, Thin Layer; Family; Female; Follow-Up Studies; Gl

1992
Acute phosphate depletion and in vitro rat proximal tubule injury: protection by glycine and acidosis.
    Kidney international, 1992, Volume: 41, Issue:6

    Topics: Acidosis; Adenosine Triphosphate; Animals; Glycine; In Vitro Techniques; Kidney Tubules, Proximal; L

1992
Acute neonatal isovaleric acidaemia presented without acidosis or ketonuria.
    Journal of inherited metabolic disease, 1991, Volume: 14, Issue:1

    Topics: Acidosis; Dietary Proteins; Female; Glycine; Hemiterpenes; Humans; Infant; Ketones; Male; Metabolism

1991
Molecular characterization of variant alpha-subunit of electron transfer flavoprotein in three patients with glutaric acidemia type II--and identification of glycine substitution for valine-157 in the sequence of the precursor, producing an unstable matur
    American journal of human genetics, 1991, Volume: 49, Issue:3

    Topics: Acidosis; Base Sequence; Blotting, Northern; Cell Line; Electron-Transferring Flavoproteins; Flavopr

1991
Role of increased cytosolic free calcium in the pathogenesis of rabbit proximal tubule cell injury and protection by glycine or acidosis.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:2

    Topics: Acidosis; Adenosine Triphosphate; Animals; Calcium; Cell Survival; Cytosol; Fura-2; Glycine; Hydroge

1991
Acetoacetyl CoA thiolase deficiency presenting as ketotic hypoglycemia.
    Pediatric research, 1987, Volume: 21, Issue:2

    Topics: Acetoacetates; Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Acidosis; Female; Glycine; Humans

1987
Biotin-responsive beta-methylcrotonylglycinuria.
    Lancet (London, England), 1971, Jul-03, Volume: 2, Issue:7714

    Topics: Acidosis; Administration, Oral; Amino Acid Metabolism, Inborn Errors; Biotin; Butyrates; Carbon Diox

1971
Application of gas chromatography-mass spectrometry in routine and research in clinical chemistry.
    Journal of chromatography, 1974, Apr-24, Volume: 91

    Topics: Acidosis; Adult; Body Fluids; Carbon Dioxide; Chemistry, Clinical; Chromatography, Gas; Clinical Lab

1974
Defective propionate carboxylation in ketotic hyperglycinaemia.
    Lancet (London, England), 1969, Apr-12, Volume: 1, Issue:7598

    Topics: Acidosis; Carbon Isotopes; Child; Coenzyme A; Female; Glycine; Humans; Infant, Newborn; Leukocytes;

1969
Ketotic hyperglycinaemia.
    Lancet (London, England), 1969, Jun-07, Volume: 1, Issue:7606

    Topics: Acidosis; Amino Acids; Child; Glycine; Humans; Lactates; Malonates; Pyruvates

1969
Localisation of enzymic defect in propionicacidaemia.
    Lancet (London, England), 1970, May-30, Volume: 1, Issue:7657

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Citric Acid Cycle; Coenzyme A; Consangu

1970
Biotin-responsive propionicacidaemia.
    Lancet (London, England), 1970, Aug-01, Volume: 2, Issue:7666

    Topics: Acidosis; Biotin; Carboxy-Lyases; Child, Preschool; Chromatography, Gas; Diet Therapy; Glycine; Huma

1970
Inhibition of the vasodilator effect of hypercapnic acidosis by hypercalcemia in dogs and rats.
    Circulation research, 1974, Volume: 35, Issue:6

    Topics: Acidosis; Animals; Buffers; Calcium; Dogs; Glycine; Hindlimb; Hydrochloric Acid; Hypercalcemia; Hype

1974
Hyperalimentation in cirrhotic patients.
    American journal of surgery, 1972, Volume: 123, Issue:1

    Topics: Acid-Base Equilibrium; Acidosis; Alanine Transaminase; Alkaline Phosphatase; Amino Acids; Ammonia; A

1972
Hyperglycinemia with ketosis due to a defect in isoleucine metabolism: a preliminary report.
    Pediatrics, 1972, Volume: 50, Issue:6

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Diet Therapy; Dietary Proteins

1972
An inherited disorder of isoleucine catabolism causing accumulation of alpha-methylacetoacetate and alpha-methyl-beta -hydroxybutyrate, and intermittent metabolic acidosis.
    Pediatric research, 1973, Volume: 7, Issue:3

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Butyrates; Cells, Cultured; Child; Child, Preschool;

1973
Propionic acid, an artefact which can leave methylmalonic acidemia undiscovered.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Dec-12, Volume: 49, Issue:2

    Topics: Acidosis; Carbohydrate Metabolism, Inborn Errors; Chromatography, Gas; Diagnosis, Differential; Fema

1973
Beta-ketothiolase deficiency as a cause of the "ketotic hyperglycinemia syndrome".
    Pediatrics, 1974, Volume: 53, Issue:2

    Topics: Acetoacetates; Acidosis; Acyltransferases; Amino Acid Metabolism, Inborn Errors; Butanones; Carbon R

1974
Propionicacidemia (ketotic hyperglycinemia): dietary treatment resulting in normal growth and development.
    Pediatrics, 1974, Volume: 53, Issue:3

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Body Height; Body Weight; Carboxy-Lyases; Child; Coe

1974
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
    The American journal of physiology, 1974, Volume: 226, Issue:4

    Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulli

1974
A block in glycine cleavage reaction as a common mechanism in ketotic and nonketotic hyperglycinemia.
    Pediatric research, 1974, Volume: 8, Issue:7

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carbon Radioisotopes; Child, Preschool; Female; Glyc

1974
Excretion of propionylglycine in propionic acidaemia.
    Clinical science, 1972, Volume: 42, Issue:6

    Topics: Acidosis; Acylation; Autoanalysis; Child, Preschool; Chromatography, Gas; Diet; Female; Glycine; Hum

1972
The oxidation of glycine and propionic acid in propionic acidemia with ketotic hyperglycinemia.
    Pediatric research, 1972, Volume: 6, Issue:6

    Topics: Acidosis; Body Fluids; Carbon Dioxide; Carbon Isotopes; Child, Preschool; Female; Fibroblasts; Glyci

1972
Vasodilator effects of local hypercapnic acidosis in dog skeletal muscle.
    The American journal of physiology, 1971, Volume: 220, Issue:6

    Topics: Acidosis; Animals; Calcium; Carbon Dioxide; Dilatation; Dogs; Glycine; Hydrochloric Acid; Hydrogen-I

1971
[A case of Ketoacidotic hyperglycinemia. 1st Italian contribution].
    Minerva pediatrica, 1971, Sep-29, Volume: 23, Issue:39

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Female; Glycine; Humans; Infant

1971
[A case of methylmalonic acid acidosis].
    Nordisk medicin, 1971, Volume: 86, Issue:49

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Female; Glycine; Humans; Infant Nutrition Disorders;

1971
Nonketotic hyperglycinemia: an in vitro study of the glycine-serine conversion in liver of three patients and the effect of dietary methionine.
    Pediatric research, 1970, Volume: 4, Issue:3

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Biopsy; Carbon Isotopes; Culture Techniques; Diet Th

1970
[Glycinosis with acidocetosis of late revelation and favorable evolution].
    Archives francaises de pediatrie, 1970, Volume: 27, Issue:5

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Glutamates; Gl

1970
Nonketotic hyperglycinemia.
    The Journal of pediatrics, 1970, Volume: 77, Issue:1

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Glycine; Humans; Infant, Newborn; Male

1970
Nonketotic hyperglycinaemia. Clinical findings and amino acid analyses on the plasma of a new case.
    Clinica chimica acta; international journal of clinical chemistry, 1970, Volume: 30, Issue:3

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Diet Therapy; Dietary Proteins; Fe

1970
Metabolism of amino acids by the perfused rat kidney.
    The American journal of physiology, 1971, Volume: 220, Issue:4

    Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Glucose; Glutamates; Glutamine; Gly

1971
Amino acid levels in plasma, liver, muscle, and kidney during and after exercise in fasted and fed rats.
    The American journal of physiology, 1971, Volume: 221, Issue:2

    Topics: Acidosis; Alanine; Amino Acids; Animals; Aspartic Acid; Fasting; Gluconeogenesis; Glutamates; Glutam

1971
Propionic acidemia in patients with ketotic hyperglycinemia.
    The Journal of pediatrics, 1971, Volume: 78, Issue:5

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromatography, Gas; Coenzy

1971
[Hereditary hyperglycinemia. Clinical picture and determination of glycoxylic and oxalic acids in the urines of one patient each with acidotic and nonacidotic form].
    Helvetica paediatrica acta, 1967, Volume: 22, Issue:2

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Body Weight; Creatinine; Female; Glycine; Glyoxylate

1967
Methylmalonic aciduria. An inborn error leading to metabolic acidosis, long-chain ketonuria and intermittent hyperglycinemia.
    The New England journal of medicine, 1968, Jun-13, Volume: 278, Issue:24

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Chromatography, Thin Layer; Coenzyme A; Dietary Prot

1968
Importance of the single case.
    The New England journal of medicine, 1968, Jun-13, Volume: 278, Issue:24

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Coenzyme A; Glycine; Humans; Infant; Intellectual Di

1968
Metabolic studies of acetoacetate, pyruvate, lactate and citrate in uremic acidosis.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 20, Issue:2

    Topics: Acetoacetates; Acidosis; Analysis of Variance; Chronic Disease; Citrates; Citric Acid Cycle; Creatin

1968
Metabolism of glycine in the nonketotic form of hyperglycinemia.
    Pediatric research, 1968, Volume: 2, Issue:4

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carbon Dioxide; Carbon Isotopes; Child; Child, Presc

1968
Methylmalonic acidemia. A disorder associated with acidosis, hyperglycinemia, and hyperlactatemia.
    Acta paediatrica Scandinavica, 1968, Volume: 57, Issue:5

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Bicarbonates; Child, Preschool; Diet Th

1968
[Glycinosis (hyperglycinemia)].
    La Presse medicale, 1968, Nov-23, Volume: 76, Issue:45

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child Development; Child, Preschool; Ch

1968
Observations on the coexistence of methylmalonic acidemia and glycinemia.
    The Journal of pediatrics, 1969, Volume: 74, Issue:5

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Female; Genes, Recessive; Glycine; Hepatomegaly; Hum

1969
Metabolism of glyoxylate in nonketotic hyperglycinemia.
    Pediatric research, 1969, Volume: 3, Issue:4

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carbon Dioxide; Carbon Isotopes; Child; Child, Presc

1969