Page last updated: 2024-10-28

glyburide and Ache

glyburide has been researched along with Ache in 47 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Research Excerpts

ExcerptRelevanceReference
"This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain."7.79The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013)
"alpha, beta-amyrin attenuates CPM-induced visceral pain and bladder edema by mechanisms that involve, at least in part, a block either of Substance P release or its receptor function, and partly by opening K(+) (ATP) channels."7.74Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels. ( Brito, GA; Chaves, MH; Cunha, GM; Lima-Júnior, RC; Rao, VS; Santos, FA; Sousa, DI, 2007)
" Also, possible interaction of pain pathways was studied using naloxone, bicuculline, L-NAME, ODQ, and glibenclamide in the formalin test in mice."4.31Bio-guided study of the antinociceptive, anti-inflammatory, and free-radical scavenging capacity of the leaves of Rhus virens Lindh. ex A. Gray and its possible mechanism of antinociception. ( Flores-Murrieta, FJ; Gonzalez-Cortazar, M; Herrera-Ruiz, ML; Juárez-Aragón, MC; Molina-Cabrera, J; Montiel-Ruiz, RM; Vargas-Ruiz, R; Zamilpa, A, 2023)
"The antinociceptive activity of the extract (at the doses of 50, 100, and 200 mg/kg) was evaluated by using chemical- and heat-induced pain models such as acetic acid-induced writhing, hot plate, tail immersion, formalin, and glutamate test."3.80Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica. ( Imam, MZ; Moniruzzaman, M, 2014)
" Analgesic (non-narcotic) activity was determined by observed decreases in abdominal writhings in intraperitoneally administered acetic acid-induced pain model in mice."3.80A preliminary evaluation of antihyperglycemic and analgesic activity of Alternanthera sessilis aerial parts. ( Faisal, M; Hossain, AI; Jahan, R; Rahman, S; Rahmatullah, M, 2014)
"This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain."3.79The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013)
" Antinociceptive activity was determined using a model of acetic acid-induced gastric pain in mice and anti-hyperglycemic activity through glucose tolerance test using glucose loaded mice."3.77Antinociceptive and anti-hyperglycemic activity of methanol leaf extract of Cyperus scariosus. ( Alam, MA; Das, AK; Jahan, R; Rahman, S; Rahmatullah, M, 2011)
" Amitriptyline (5, 10 mg/ kg), maprotiline (10, 20 mg/kg) and fluvoxamine (20 and 30 mg/kg) effectively inhibited pain induction caused by the second phase of the formalin test."3.77Effect of glibenclamide on antinociceptive effects of antidepressants of different classes. ( Amin, B; Hajhashemi, V, 2011)
" The accompanying mechanical allodynia may be reduced by the intrathecal administration of adenosine."3.77Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats. ( Hahm, KD; Jeong, SM; Kim, YK; Lee, C; Leem, JG; Park, PH; Shin, JW; Song, JG, 2011)
"The present work evaluated the effects of the methanol extract of the bulbs of Dioscorea bulbifera in inflammatory and neuropathic models of pain and further investigated its possible mechanism of action."3.76Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation. ( Andrade, EL; Calixto, JB; Dutra, RC; Nguelefack, TB; Paszcuk, AF; Tapondjou, LA, 2010)
"alpha, beta-amyrin attenuates CPM-induced visceral pain and bladder edema by mechanisms that involve, at least in part, a block either of Substance P release or its receptor function, and partly by opening K(+) (ATP) channels."3.74Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels. ( Brito, GA; Chaves, MH; Cunha, GM; Lima-Júnior, RC; Rao, VS; Santos, FA; Sousa, DI, 2007)
"Zaprinast is a phosphodiesterase inhibitor that is active in various models of pain when administered locally."3.73Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test. ( Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH, 2005)
"Bone cancer pain is a major clinical problem and remains difficult to treat."1.40Role of ATP-sensitive potassium channels in modulating nociception in rat model of bone cancer pain. ( Fan, L; Pan, HL; Ren, J; Tian, Y; Wang, X; Wang, Y; Wu, J; Xia, H; Xu, L; Yang, S; Yao, W; Zhang, C; Zhang, D, 2014)
" To evaluate the possibility of a pharmacokinetic interaction, the oral bioavailability of diclofenac (18 mg/kg) was studied in presence and the absence of glibenclamide (10 mg/kg)."1.35Pharmacokinetics and pharmacodynamics of diclofenac in the presence and absence of glibenclamide in the rat. ( Castañeda-Hernández, G; León-Reyes, MR; Ortiz, MI, 2008)
" Therefore, in view of the vast clinical uses and interactions of NSAIDs with commonly used therapeutic agents, the interaction of the NSAID diclofenac and glibenclamide was investigated about pharmacokinetic profile and antinociceptive effect in rats."1.35Pharmacokinetic of diclofenac in the presence and absence of glibenclamide in the rat. ( Castañeda-Hernández, G; León-Reyes, MR; Ortiz, MI, 2009)
"Pinacidil activity was not blocked by L-NAME, D-NAME, 7-nitroindazole, ODQ, KT-5823 or okadaic acid."1.33The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin. ( Flores-Murrieta, FJ; Granados-Soto, V; Mixcoatl-Zecuatl, T, 2006)
"pinacidil was significantly antagonized by i."1.31Effect of diabetes on pinacidil-induced antinociception in mice. ( Kamei, J; Onodera, K; Zushida, K, 2002)
"apomorphine or morphine were observed and analyzed in rats by tail-flick (TF) test."1.30Endogenous opioids and ATP-sensitive potassium channels are involved in the mediation of apomorphine-induced antinociception at the spinal level: a behavioral study in rats. ( Hu, WM; Kang, YM; Qiao, JT, 1998)
" Diazoxide (2 microg/mouse) shifted morphine's dose-response curve 47-fold, while levcromakalim (0."1.30ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides. ( Lohmann, AB; Welch, SP, 1999)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (6.38)18.2507
2000's18 (38.30)29.6817
2010's23 (48.94)24.3611
2020's3 (6.38)2.80

Authors

AuthorsStudies
Mohammadi, S1
Fakhri, S1
Mohammadi-Farani, A1
Farzaei, MH1
Abbaszadeh, F1
Vargas-Ruiz, R1
Montiel-Ruiz, RM1
Zamilpa, A1
Gonzalez-Cortazar, M1
Herrera-Ruiz, ML1
Molina-Cabrera, J1
Juárez-Aragón, MC1
Flores-Murrieta, FJ2
Olorukooba, AB1
Odoma, S1
Oliveira, PA1
Capim, SL1
Gonçalves, GM1
Laureano-Melo, R1
Côrtes, WDS1
Vasconcellos, MLAA1
Marinho, BG1
Adeyemi, OO1
Ishola, IO1
Adesanya, ET1
Alohan, DO1
Gama, KB1
Quintans, JS1
Antoniolli, AR1
Quintans-Júnior, LJ1
Santana, WA1
Branco, A1
Soares, MB1
Villarreal, CF1
Dutra, MM1
Godin, AM1
César, IC1
Nascimento, EB1
Menezes, RR1
Ferreira, WC1
Soares, DG1
Seniuk, JG1
Araújo, DP1
Bastos, LF1
Pianetti, GA1
de Fátima, Â1
Machado, RR1
Coelho, MM1
Rahmatullah, M5
Hossain, M1
Mahmud, A1
Sultana, N1
Rahman, SM1
Islam, MR1
Khatoon, MS1
Jahan, S1
Islam, F1
Haque, ME1
Rahman, S4
Jahan, R4
Xia, H1
Zhang, D1
Yang, S1
Wang, Y1
Xu, L1
Wu, J1
Ren, J1
Yao, W1
Fan, L1
Zhang, C1
Tian, Y1
Pan, HL1
Wang, X1
Imam, MZ1
Moniruzzaman, M1
Hossain, AI1
Faisal, M1
León-Reyes, MR2
Castañeda-Hernández, G5
Ortiz, MI4
González-Rodríguez, S1
Hidalgo, A1
Baamonde, A1
Menéndez, L1
Nguelefack, TB1
Dutra, RC1
Paszcuk, AF1
Andrade, EL1
Tapondjou, LA1
Calixto, JB2
Pereira, TP1
Campos, AR2
Leal, LK1
Pierdoná, TM1
Toyama, MH1
Monteiro, HS1
Martins, AM1
Khanna, N1
Malhotra, RS1
Mehta, AK1
Garg, GR1
Halder, S1
Sharma, KK1
Quock, LP1
Zhang, Y1
Chung, E1
Ohgami, Y1
Shirachi, DY1
Quock, RM1
Alam, MA1
Das, AK2
Mohamad, AS1
Akhtar, MN1
Khalivulla, SI1
Perimal, EK1
Khalid, MH1
Ong, HM1
Zareen, S1
Akira, A1
Israf, DA1
Lajis, N1
Sulaiman, MR1
Hajhashemi, V1
Amin, B1
Song, JG1
Hahm, KD1
Kim, YK1
Leem, JG1
Lee, C1
Jeong, SM1
Park, PH1
Shin, JW1
Du, X1
Wang, C1
Zhang, H1
Reza, H1
Haq, WM1
Negrete, R1
Hervera, A1
Leánez, S1
Martín-Campos, JM1
Pol, O1
Mizokami, SS1
Arakawa, NS1
Ambrosio, SR1
Zarpelon, AC1
Casagrande, R1
Cunha, TM1
Ferreira, SH2
Cunha, FQ2
Verri, WA1
Afify, EA1
Khedr, MM1
Omar, AG1
Nasser, SA1
Zushida, K1
Onodera, K1
Kamei, J1
Santos, AR1
Trentin, AP1
Ferreira, J1
Yunes, RA1
Sarantopoulos, C1
McCallum, B1
Sapunar, D1
Kwok, WM1
Hogan, Q1
Lozano-Cuenca, J1
Granados-Soto, V5
Santos, FA3
Jeferson, FA1
Santos, CC1
Silveira, ER1
Rao, VS3
Yoon, MH1
Choi, JI1
Bae, HB1
Jeong, SW1
Chung, SS1
Yoo, KY1
Jeong, CY1
Kim, SJ1
Chung, ST1
Kim, CM1
Mixcoatl-Zecuatl, T1
Mortensen, UM1
Nielsen-Kudsk, JE1
Sondergaard, HM1
Jakobsen, P1
Jensen, BS1
Schmitz, O1
Nielsen, TT1
Maia, JL1
Lima-Júnior, RC2
Melo, CM1
David, JP1
David, JM1
Brito, GA2
Sachs, D1
Vale, ML1
Lotufo, CM1
Ribeiro, RA1
Jesse, CR1
Savegnago, L1
Nogueira, CW1
Sousa, DI1
Cunha, GM1
Chaves, MH1
Raffa, RB1
Codd, EE1
Kang, YM1
Hu, WM1
Qiao, JT1
Lohmann, AB1
Welch, SP1
Soares, AC1
Duarte, ID1
Lázaro-Ibáñez, GG1
Torres-López, JE2
Rosas, R1
Vidal-Cantú, GC1

Trials

1 trial available for glyburide and Ache

ArticleYear
Effect of the oral hypoglycaemic sulphonylurea glibenclamide, a blocker of ATP-sensitive potassium channels, on walking distance in patients with intermittent claudication.
    Diabetic medicine : a journal of the British Diabetic Association, 2006, Volume: 23, Issue:3

    Topics: Adenosine Triphosphate; Administration, Oral; Aged; Blood Glucose; Blood Pressure; Cross-Over Studie

2006

Other Studies

46 other studies available for glyburide and Ache

ArticleYear
Astaxanthin engages the l-arginine/NO/cGMP/KATP channel signaling pathway toward antinociceptive effects.
    Behavioural pharmacology, 2021, 12-01, Volume: 32, Issue:8

    Topics: Analgesics; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug;

2021
Bio-guided study of the antinociceptive, anti-inflammatory, and free-radical scavenging capacity of the leaves of Rhus virens Lindh. ex A. Gray and its possible mechanism of antinociception.
    Journal of ethnopharmacology, 2023, Jan-10, Volume: 300

    Topics: Adenosine Triphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Bicuculline; Ed

2023
Elucidation of the possible mechanism of analgesic action of methanol stem bark extract of Uapaca togoensis pax in mice.
    Journal of ethnopharmacology, 2019, Dec-05, Volume: 245

    Topics: Acetic Acid; Analgesics; Animals; Atropine; Coffea; Female; Glyburide; Lethal Dose 50; Male; Methano

2019
Pharmacological evaluation underlying the antinociceptive activity of two new hybrids NSAIDs tetrahydropyran derivatives.
    Fundamental & clinical pharmacology, 2020, Volume: 34, Issue:3

    Topics: Adenosine Triphosphate; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Stero

2020
Antinociceptive and anti-inflammatory properties of Tetracera alnifolia Willd. (Dilleniaceae) hydroethanolic leaf extract.
    Journal of basic and clinical physiology and pharmacology, 2018, Oct-17, Volume: 30, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arginine; Arthritis; Carrageenan; Dilleniaceae; Edema

2018
Evidence for the involvement of descending pain-inhibitory mechanisms in the antinociceptive effect of hecogenin acetate.
    Journal of natural products, 2013, Apr-26, Volume: 76, Issue:4

    Topics: Agave; Analgesics; Animals; Glyburide; KATP Channels; Male; Mice; Molecular Structure; Naltrexone; P

2013
Activity of nicorandil, a nicotinamide derivative with a nitrate group, in the experimental model of pain induced by formaldehyde in mice.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 106

    Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Glyburi

2013
Antihyperglycemic and antinociceptive activity evaluation of 'khoyer' prepared from boiling the wood of Acacia catechu in water.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2013, Volume: 10, Issue:4

    Topics: Acacia; Acetic Acid; Analgesics; Animals; Aspirin; Bangladesh; Behavior, Animal; Blood Glucose; Diab

2013
Evaluation of antihyperglycemic and antinociceptive activity of Xanthium indicum stem extract in Swiss albino mice.
    BMC complementary and alternative medicine, 2013, Oct-30, Volume: 13

    Topics: Analgesics; Animals; Bangladesh; Blood Glucose; Drug Evaluation, Preclinical; Glucose Tolerance Test

2013
Role of ATP-sensitive potassium channels in modulating nociception in rat model of bone cancer pain.
    Brain research, 2014, Mar-20, Volume: 1554

    Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Glyburide; Hyperalgesia;

2014
Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica.
    Journal of ethnopharmacology, 2014, May-28, Volume: 154, Issue:1

    Topics: Acetic Acid; Anacardiaceae; Analgesics; Animals; Cyclic GMP; Ethanol; Female; Formaldehyde; Glutamic

2014
A preliminary evaluation of antihyperglycemic and analgesic activity of Alternanthera sessilis aerial parts.
    BMC complementary and alternative medicine, 2014, May-24, Volume: 14

    Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Aspirin; Bangladesh; Blood Glucose; Drug Evaluation

2014
Pharmacokinetics and pharmacodynamics of diclofenac in the presence and absence of glibenclamide in the rat.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2008, Volume: 11, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Dic

2008
Spinal and peripheral mechanisms involved in the enhancement of morphine analgesia in acutely inflamed mice.
    Cellular and molecular neurobiology, 2010, Volume: 30, Issue:1

    Topics: Acute Disease; Analgesia; Animals; Carrageenan; Glyburide; Inflammation; Injections, Spinal; Mice; M

2010
Pharmacokinetic of diclofenac in the presence and absence of glibenclamide in the rat.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2009, Volume: 12, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac;

2009
Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation.
    Journal of ethnopharmacology, 2010, Apr-21, Volume: 128, Issue:3

    Topics: Animals; Cyclic GMP; Female; Freund's Adjuvant; Glyburide; Hyperalgesia; Inflammation; KATP Channels

2010
K+(ATP) channels-independent analgesic action of Crotalus durissus cumanensis venom.
    Natural product communications, 2010, Volume: 5, Issue:7

    Topics: Analgesics; Animals; Crotalus; Glyburide; KATP Channels; Male; Mice; Pain; Potassium Channel Blocker

2010
Interaction of morphine and potassium channel openers on experimental models of pain in mice.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:4

    Topics: Animals; Calcium Channel Agonists; Cromakalim; Diazoxide; Drug Interactions; Drug Therapy, Combinati

2011
The acute antinociceptive effect of HBO₂ is mediated by a NO-cyclic GMP-PKG-KATP channel pathway in mice.
    Brain research, 2011, Jan-12, Volume: 1368

    Topics: Acetic Acid; Animals; Benzoates; Cyclic GMP-Dependent Protein Kinases; Glyburide; Guanylate Cyclase;

2011
Antinociceptive and anti-hyperglycemic activity of methanol leaf extract of Cyperus scariosus.
    Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Aspirin; Cyperus; Dose-Response Relationship, Drug; Glucose Tolera

2011
Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K(+) channels pathway in the systemic antinociception of flavokawin B.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 108, Issue:6

    Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flav

2011
Effect of glibenclamide on antinociceptive effects of antidepressants of different classes.
    Clinics (Sao Paulo, Brazil), 2011, Volume: 66, Issue:2

    Topics: Amitriptyline; Analgesics; Analysis of Variance; Animals; Antidepressive Agents; Drug Interactions;

2011
Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:6

    Topics: 4-Aminopyridine; Adenosine; Adenosine Triphosphate; Animals; Glyburide; Humans; Hyperalgesia; Inject

2011
Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats.
    Molecular pain, 2011, May-14, Volume: 7

    Topics: Animals; Behavior, Animal; Bradykinin; Diazoxide; Ganglia, Spinal; Glyburide; Ion Channel Gating; KA

2011
Anti-hyperglycemic and antinociceptive activity of methanol leaf and stem extract of Nypa fruticans Wurmb.
    Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:4

    Topics: Acetic Acid; Analgesics; Animals; Arecaceae; Aspirin; Blood Glucose; Glucose; Glyburide; Hyperglycem

2011
The antinociceptive effects of JWH-015 in chronic inflammatory pain are produced by nitric oxide-cGMP-PKG-KATP pathway activation mediated by opioids.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Analgesics; Analgesics, Opioid; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagon

2011
Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway.
    Journal of natural products, 2012, May-25, Volume: 75, Issue:5

    Topics: Acetic Acid; Administration, Oral; Animals; Asteraceae; Carbazoles; Cyclic GMP-Dependent Protein Kin

2012
The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats.
    Fundamental & clinical pharmacology, 2013, Volume: 27, Issue:6

    Topics: Acute Pain; Analgesics, Opioid; Animals; Chemical and Drug Induced Liver Injury; Diazoxide; Disease

2013
Effect of diabetes on pinacidil-induced antinociception in mice.
    European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3

    Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glyburide; Injections, I

2002
Mechanisms involved in the antinociception caused by compound MV8612 isolated from Mandevilla velutina in mice.
    Brain research, 2003, Jan-31, Volume: 961, Issue:2

    Topics: Analgesics; Animals; Apamin; Bradykinin; Capsaicin; Charybdotoxin; Formaldehyde; Glyburide; Glycosid

2003
ATP-sensitive potassium channels in rat primary afferent neurons: the effect of neuropathic injury and gabapentin.
    Neuroscience letters, 2003, Jun-12, Volume: 343, Issue:3

    Topics: Acetates; Amines; Animals; ATP-Binding Cassette Transporters; Basal Ganglia; Cyclohexanecarboxylic A

2003
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib.
    European journal of pharmacology, 2005, Apr-18, Volume: 513, Issue:1-2

    Topics: Analgesics; Animals; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship

2005
Antinociceptive effect of leaf essential oil from Croton sonderianus in mice.
    Life sciences, 2005, Oct-21, Volume: 77, Issue:23

    Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Capsaicin; Croton; Disease Models, Animal; Dose-

2005
Pharmacological evidence for the activation of Ca2+-activated K+ channels by meloxicam in the formalin test.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:4

    Topics: 4-Aminopyridine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Apamin; Behavior, Animal;

2005
Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test.
    Neuroscience letters, 2005, Dec-23, Volume: 390, Issue:2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analgesics; Animals; Cyclic GMP; Formaldehyde; Glyburide; Injec

2005
The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Pro

2006
Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms.
    Pharmacological research, 2006, Volume: 54, Issue:4

    Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Capsaicin; Coloring Agents; Enzyme Inhibi

2006
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
    The European journal of neuroscience, 2006, Volume: 24, Issue:4

    Topics: Adenosine Triphosphate; Analgesia; Analgesics; Animals; Arginine; Bucladesine; Carbazoles; Cells, Cu

2006
Role of nitric oxide/cyclic GMP/K(+) channel pathways in the antinociceptive effect caused by 2,3-bis(mesitylseleno)propenol.
    Life sciences, 2007, Dec-14, Volume: 81, Issue:25-26

    Topics: Analgesics; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Formaldehyde; G

2007
Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2007, Volume: 56, Issue:12

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclophosphamide; Cysti

2007
Lack of glibenclamide or TEA affinity for opioid receptors: further evidence for in vivo modulation of antinociception at K+ channels.
    Brain research, 1994, Jul-04, Volume: 650, Issue:1

    Topics: Amino Acid Sequence; Animals; Glyburide; Male; Molecular Sequence Data; Pain; Potassium Channel Bloc

1994
Endogenous opioids and ATP-sensitive potassium channels are involved in the mediation of apomorphine-induced antinociception at the spinal level: a behavioral study in rats.
    Brain research bulletin, 1998, Volume: 46, Issue:3

    Topics: Adenosine Triphosphate; Animals; Apomorphine; Dopamine Agonists; Endorphins; Female; Glyburide; Inje

1998
ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides.
    European journal of pharmacology, 1999, Dec-03, Volume: 385, Issue:2-3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine

1999
Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: 4-Aminopyridine; Adenosine Triphosphate; Analgesics; Animals; Apamin; Cesium; Charybdotoxin; Dibutyr

2001
Participation of the nitric oxide-cyclic GMP-ATP-sensitive K(+) channel pathway in the antinociceptive action of ketorolac.
    European journal of pharmacology, 2001, Aug-24, Volume: 426, Issue:1-2

    Topics: Adenosine Triphosphate; Analgesics; Animals; Behavior, Animal; Cyclic AMP; Dose-Response Relationshi

2001
Pharmacological evidence for the activation of K(+) channels by diclofenac.
    European journal of pharmacology, 2002, Mar-01, Volume: 438, Issue:1-2

    Topics: 4-Aminopyridine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; A

2002