glyburide has been researched along with Ache in 47 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain." | 7.79 | The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013) |
| "alpha, beta-amyrin attenuates CPM-induced visceral pain and bladder edema by mechanisms that involve, at least in part, a block either of Substance P release or its receptor function, and partly by opening K(+) (ATP) channels." | 7.74 | Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels. ( Brito, GA; Chaves, MH; Cunha, GM; Lima-Júnior, RC; Rao, VS; Santos, FA; Sousa, DI, 2007) |
| " Also, possible interaction of pain pathways was studied using naloxone, bicuculline, L-NAME, ODQ, and glibenclamide in the formalin test in mice." | 4.31 | Bio-guided study of the antinociceptive, anti-inflammatory, and free-radical scavenging capacity of the leaves of Rhus virens Lindh. ex A. Gray and its possible mechanism of antinociception. ( Flores-Murrieta, FJ; Gonzalez-Cortazar, M; Herrera-Ruiz, ML; Juárez-Aragón, MC; Molina-Cabrera, J; Montiel-Ruiz, RM; Vargas-Ruiz, R; Zamilpa, A, 2023) |
| "The antinociceptive activity of the extract (at the doses of 50, 100, and 200 mg/kg) was evaluated by using chemical- and heat-induced pain models such as acetic acid-induced writhing, hot plate, tail immersion, formalin, and glutamate test." | 3.80 | Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica. ( Imam, MZ; Moniruzzaman, M, 2014) |
| " Analgesic (non-narcotic) activity was determined by observed decreases in abdominal writhings in intraperitoneally administered acetic acid-induced pain model in mice." | 3.80 | A preliminary evaluation of antihyperglycemic and analgesic activity of Alternanthera sessilis aerial parts. ( Faisal, M; Hossain, AI; Jahan, R; Rahman, S; Rahmatullah, M, 2014) |
| "This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain." | 3.79 | The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013) |
| " Antinociceptive activity was determined using a model of acetic acid-induced gastric pain in mice and anti-hyperglycemic activity through glucose tolerance test using glucose loaded mice." | 3.77 | Antinociceptive and anti-hyperglycemic activity of methanol leaf extract of Cyperus scariosus. ( Alam, MA; Das, AK; Jahan, R; Rahman, S; Rahmatullah, M, 2011) |
| " Amitriptyline (5, 10 mg/ kg), maprotiline (10, 20 mg/kg) and fluvoxamine (20 and 30 mg/kg) effectively inhibited pain induction caused by the second phase of the formalin test." | 3.77 | Effect of glibenclamide on antinociceptive effects of antidepressants of different classes. ( Amin, B; Hajhashemi, V, 2011) |
| " The accompanying mechanical allodynia may be reduced by the intrathecal administration of adenosine." | 3.77 | Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats. ( Hahm, KD; Jeong, SM; Kim, YK; Lee, C; Leem, JG; Park, PH; Shin, JW; Song, JG, 2011) |
| "The present work evaluated the effects of the methanol extract of the bulbs of Dioscorea bulbifera in inflammatory and neuropathic models of pain and further investigated its possible mechanism of action." | 3.76 | Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation. ( Andrade, EL; Calixto, JB; Dutra, RC; Nguelefack, TB; Paszcuk, AF; Tapondjou, LA, 2010) |
| "alpha, beta-amyrin attenuates CPM-induced visceral pain and bladder edema by mechanisms that involve, at least in part, a block either of Substance P release or its receptor function, and partly by opening K(+) (ATP) channels." | 3.74 | Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels. ( Brito, GA; Chaves, MH; Cunha, GM; Lima-Júnior, RC; Rao, VS; Santos, FA; Sousa, DI, 2007) |
| "Zaprinast is a phosphodiesterase inhibitor that is active in various models of pain when administered locally." | 3.73 | Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test. ( Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH, 2005) |
| "Bone cancer pain is a major clinical problem and remains difficult to treat." | 1.40 | Role of ATP-sensitive potassium channels in modulating nociception in rat model of bone cancer pain. ( Fan, L; Pan, HL; Ren, J; Tian, Y; Wang, X; Wang, Y; Wu, J; Xia, H; Xu, L; Yang, S; Yao, W; Zhang, C; Zhang, D, 2014) |
| " To evaluate the possibility of a pharmacokinetic interaction, the oral bioavailability of diclofenac (18 mg/kg) was studied in presence and the absence of glibenclamide (10 mg/kg)." | 1.35 | Pharmacokinetics and pharmacodynamics of diclofenac in the presence and absence of glibenclamide in the rat. ( Castañeda-Hernández, G; León-Reyes, MR; Ortiz, MI, 2008) |
| " Therefore, in view of the vast clinical uses and interactions of NSAIDs with commonly used therapeutic agents, the interaction of the NSAID diclofenac and glibenclamide was investigated about pharmacokinetic profile and antinociceptive effect in rats." | 1.35 | Pharmacokinetic of diclofenac in the presence and absence of glibenclamide in the rat. ( Castañeda-Hernández, G; León-Reyes, MR; Ortiz, MI, 2009) |
| "Pinacidil activity was not blocked by L-NAME, D-NAME, 7-nitroindazole, ODQ, KT-5823 or okadaic acid." | 1.33 | The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin. ( Flores-Murrieta, FJ; Granados-Soto, V; Mixcoatl-Zecuatl, T, 2006) |
| "pinacidil was significantly antagonized by i." | 1.31 | Effect of diabetes on pinacidil-induced antinociception in mice. ( Kamei, J; Onodera, K; Zushida, K, 2002) |
| "apomorphine or morphine were observed and analyzed in rats by tail-flick (TF) test." | 1.30 | Endogenous opioids and ATP-sensitive potassium channels are involved in the mediation of apomorphine-induced antinociception at the spinal level: a behavioral study in rats. ( Hu, WM; Kang, YM; Qiao, JT, 1998) |
| " Diazoxide (2 microg/mouse) shifted morphine's dose-response curve 47-fold, while levcromakalim (0." | 1.30 | ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides. ( Lohmann, AB; Welch, SP, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (6.38) | 18.2507 |
| 2000's | 18 (38.30) | 29.6817 |
| 2010's | 23 (48.94) | 24.3611 |
| 2020's | 3 (6.38) | 2.80 |
| Authors | Studies |
|---|---|
| Mohammadi, S | 1 |
| Fakhri, S | 1 |
| Mohammadi-Farani, A | 1 |
| Farzaei, MH | 1 |
| Abbaszadeh, F | 1 |
| Vargas-Ruiz, R | 1 |
| Montiel-Ruiz, RM | 1 |
| Zamilpa, A | 1 |
| Gonzalez-Cortazar, M | 1 |
| Herrera-Ruiz, ML | 1 |
| Molina-Cabrera, J | 1 |
| Juárez-Aragón, MC | 1 |
| Flores-Murrieta, FJ | 2 |
| Olorukooba, AB | 1 |
| Odoma, S | 1 |
| Oliveira, PA | 1 |
| Capim, SL | 1 |
| Gonçalves, GM | 1 |
| Laureano-Melo, R | 1 |
| Côrtes, WDS | 1 |
| Vasconcellos, MLAA | 1 |
| Marinho, BG | 1 |
| Adeyemi, OO | 1 |
| Ishola, IO | 1 |
| Adesanya, ET | 1 |
| Alohan, DO | 1 |
| Gama, KB | 1 |
| Quintans, JS | 1 |
| Antoniolli, AR | 1 |
| Quintans-Júnior, LJ | 1 |
| Santana, WA | 1 |
| Branco, A | 1 |
| Soares, MB | 1 |
| Villarreal, CF | 1 |
| Dutra, MM | 1 |
| Godin, AM | 1 |
| César, IC | 1 |
| Nascimento, EB | 1 |
| Menezes, RR | 1 |
| Ferreira, WC | 1 |
| Soares, DG | 1 |
| Seniuk, JG | 1 |
| Araújo, DP | 1 |
| Bastos, LF | 1 |
| Pianetti, GA | 1 |
| de Fátima, Â | 1 |
| Machado, RR | 1 |
| Coelho, MM | 1 |
| Rahmatullah, M | 5 |
| Hossain, M | 1 |
| Mahmud, A | 1 |
| Sultana, N | 1 |
| Rahman, SM | 1 |
| Islam, MR | 1 |
| Khatoon, MS | 1 |
| Jahan, S | 1 |
| Islam, F | 1 |
| Haque, ME | 1 |
| Rahman, S | 4 |
| Jahan, R | 4 |
| Xia, H | 1 |
| Zhang, D | 1 |
| Yang, S | 1 |
| Wang, Y | 1 |
| Xu, L | 1 |
| Wu, J | 1 |
| Ren, J | 1 |
| Yao, W | 1 |
| Fan, L | 1 |
| Zhang, C | 1 |
| Tian, Y | 1 |
| Pan, HL | 1 |
| Wang, X | 1 |
| Imam, MZ | 1 |
| Moniruzzaman, M | 1 |
| Hossain, AI | 1 |
| Faisal, M | 1 |
| León-Reyes, MR | 2 |
| Castañeda-Hernández, G | 5 |
| Ortiz, MI | 4 |
| González-Rodríguez, S | 1 |
| Hidalgo, A | 1 |
| Baamonde, A | 1 |
| Menéndez, L | 1 |
| Nguelefack, TB | 1 |
| Dutra, RC | 1 |
| Paszcuk, AF | 1 |
| Andrade, EL | 1 |
| Tapondjou, LA | 1 |
| Calixto, JB | 2 |
| Pereira, TP | 1 |
| Campos, AR | 2 |
| Leal, LK | 1 |
| Pierdoná, TM | 1 |
| Toyama, MH | 1 |
| Monteiro, HS | 1 |
| Martins, AM | 1 |
| Khanna, N | 1 |
| Malhotra, RS | 1 |
| Mehta, AK | 1 |
| Garg, GR | 1 |
| Halder, S | 1 |
| Sharma, KK | 1 |
| Quock, LP | 1 |
| Zhang, Y | 1 |
| Chung, E | 1 |
| Ohgami, Y | 1 |
| Shirachi, DY | 1 |
| Quock, RM | 1 |
| Alam, MA | 1 |
| Das, AK | 2 |
| Mohamad, AS | 1 |
| Akhtar, MN | 1 |
| Khalivulla, SI | 1 |
| Perimal, EK | 1 |
| Khalid, MH | 1 |
| Ong, HM | 1 |
| Zareen, S | 1 |
| Akira, A | 1 |
| Israf, DA | 1 |
| Lajis, N | 1 |
| Sulaiman, MR | 1 |
| Hajhashemi, V | 1 |
| Amin, B | 1 |
| Song, JG | 1 |
| Hahm, KD | 1 |
| Kim, YK | 1 |
| Leem, JG | 1 |
| Lee, C | 1 |
| Jeong, SM | 1 |
| Park, PH | 1 |
| Shin, JW | 1 |
| Du, X | 1 |
| Wang, C | 1 |
| Zhang, H | 1 |
| Reza, H | 1 |
| Haq, WM | 1 |
| Negrete, R | 1 |
| Hervera, A | 1 |
| Leánez, S | 1 |
| Martín-Campos, JM | 1 |
| Pol, O | 1 |
| Mizokami, SS | 1 |
| Arakawa, NS | 1 |
| Ambrosio, SR | 1 |
| Zarpelon, AC | 1 |
| Casagrande, R | 1 |
| Cunha, TM | 1 |
| Ferreira, SH | 2 |
| Cunha, FQ | 2 |
| Verri, WA | 1 |
| Afify, EA | 1 |
| Khedr, MM | 1 |
| Omar, AG | 1 |
| Nasser, SA | 1 |
| Zushida, K | 1 |
| Onodera, K | 1 |
| Kamei, J | 1 |
| Santos, AR | 1 |
| Trentin, AP | 1 |
| Ferreira, J | 1 |
| Yunes, RA | 1 |
| Sarantopoulos, C | 1 |
| McCallum, B | 1 |
| Sapunar, D | 1 |
| Kwok, WM | 1 |
| Hogan, Q | 1 |
| Lozano-Cuenca, J | 1 |
| Granados-Soto, V | 5 |
| Santos, FA | 3 |
| Jeferson, FA | 1 |
| Santos, CC | 1 |
| Silveira, ER | 1 |
| Rao, VS | 3 |
| Yoon, MH | 1 |
| Choi, JI | 1 |
| Bae, HB | 1 |
| Jeong, SW | 1 |
| Chung, SS | 1 |
| Yoo, KY | 1 |
| Jeong, CY | 1 |
| Kim, SJ | 1 |
| Chung, ST | 1 |
| Kim, CM | 1 |
| Mixcoatl-Zecuatl, T | 1 |
| Mortensen, UM | 1 |
| Nielsen-Kudsk, JE | 1 |
| Sondergaard, HM | 1 |
| Jakobsen, P | 1 |
| Jensen, BS | 1 |
| Schmitz, O | 1 |
| Nielsen, TT | 1 |
| Maia, JL | 1 |
| Lima-Júnior, RC | 2 |
| Melo, CM | 1 |
| David, JP | 1 |
| David, JM | 1 |
| Brito, GA | 2 |
| Sachs, D | 1 |
| Vale, ML | 1 |
| Lotufo, CM | 1 |
| Ribeiro, RA | 1 |
| Jesse, CR | 1 |
| Savegnago, L | 1 |
| Nogueira, CW | 1 |
| Sousa, DI | 1 |
| Cunha, GM | 1 |
| Chaves, MH | 1 |
| Raffa, RB | 1 |
| Codd, EE | 1 |
| Kang, YM | 1 |
| Hu, WM | 1 |
| Qiao, JT | 1 |
| Lohmann, AB | 1 |
| Welch, SP | 1 |
| Soares, AC | 1 |
| Duarte, ID | 1 |
| Lázaro-Ibáñez, GG | 1 |
| Torres-López, JE | 2 |
| Rosas, R | 1 |
| Vidal-Cantú, GC | 1 |
1 trial available for glyburide and Ache
| Article | Year |
|---|---|
Effect of the oral hypoglycaemic sulphonylurea glibenclamide, a blocker of ATP-sensitive potassium channels, on walking distance in patients with intermittent claudication.
Topics: Adenosine Triphosphate; Administration, Oral; Aged; Blood Glucose; Blood Pressure; Cross-Over Studie | 2006 |
46 other studies available for glyburide and Ache
| Article | Year |
|---|---|
Astaxanthin engages the l-arginine/NO/cGMP/KATP channel signaling pathway toward antinociceptive effects.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; | 2021 |
Bio-guided study of the antinociceptive, anti-inflammatory, and free-radical scavenging capacity of the leaves of Rhus virens Lindh. ex A. Gray and its possible mechanism of antinociception.
Topics: Adenosine Triphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Bicuculline; Ed | 2023 |
Elucidation of the possible mechanism of analgesic action of methanol stem bark extract of Uapaca togoensis pax in mice.
Topics: Acetic Acid; Analgesics; Animals; Atropine; Coffea; Female; Glyburide; Lethal Dose 50; Male; Methano | 2019 |
Pharmacological evaluation underlying the antinociceptive activity of two new hybrids NSAIDs tetrahydropyran derivatives.
Topics: Adenosine Triphosphate; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Stero | 2020 |
Antinociceptive and anti-inflammatory properties of Tetracera alnifolia Willd. (Dilleniaceae) hydroethanolic leaf extract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arginine; Arthritis; Carrageenan; Dilleniaceae; Edema | 2018 |
Evidence for the involvement of descending pain-inhibitory mechanisms in the antinociceptive effect of hecogenin acetate.
Topics: Agave; Analgesics; Animals; Glyburide; KATP Channels; Male; Mice; Molecular Structure; Naltrexone; P | 2013 |
Activity of nicorandil, a nicotinamide derivative with a nitrate group, in the experimental model of pain induced by formaldehyde in mice.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Glyburi | 2013 |
Antihyperglycemic and antinociceptive activity evaluation of 'khoyer' prepared from boiling the wood of Acacia catechu in water.
Topics: Acacia; Acetic Acid; Analgesics; Animals; Aspirin; Bangladesh; Behavior, Animal; Blood Glucose; Diab | 2013 |
Evaluation of antihyperglycemic and antinociceptive activity of Xanthium indicum stem extract in Swiss albino mice.
Topics: Analgesics; Animals; Bangladesh; Blood Glucose; Drug Evaluation, Preclinical; Glucose Tolerance Test | 2013 |
Role of ATP-sensitive potassium channels in modulating nociception in rat model of bone cancer pain.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Glyburide; Hyperalgesia; | 2014 |
Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica.
Topics: Acetic Acid; Anacardiaceae; Analgesics; Animals; Cyclic GMP; Ethanol; Female; Formaldehyde; Glutamic | 2014 |
A preliminary evaluation of antihyperglycemic and analgesic activity of Alternanthera sessilis aerial parts.
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Aspirin; Bangladesh; Blood Glucose; Drug Evaluation | 2014 |
Pharmacokinetics and pharmacodynamics of diclofenac in the presence and absence of glibenclamide in the rat.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Dic | 2008 |
Spinal and peripheral mechanisms involved in the enhancement of morphine analgesia in acutely inflamed mice.
Topics: Acute Disease; Analgesia; Animals; Carrageenan; Glyburide; Inflammation; Injections, Spinal; Mice; M | 2010 |
Pharmacokinetic of diclofenac in the presence and absence of glibenclamide in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; | 2009 |
Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation.
Topics: Animals; Cyclic GMP; Female; Freund's Adjuvant; Glyburide; Hyperalgesia; Inflammation; KATP Channels | 2010 |
K+(ATP) channels-independent analgesic action of Crotalus durissus cumanensis venom.
Topics: Analgesics; Animals; Crotalus; Glyburide; KATP Channels; Male; Mice; Pain; Potassium Channel Blocker | 2010 |
Interaction of morphine and potassium channel openers on experimental models of pain in mice.
Topics: Animals; Calcium Channel Agonists; Cromakalim; Diazoxide; Drug Interactions; Drug Therapy, Combinati | 2011 |
The acute antinociceptive effect of HBO₂ is mediated by a NO-cyclic GMP-PKG-KATP channel pathway in mice.
Topics: Acetic Acid; Animals; Benzoates; Cyclic GMP-Dependent Protein Kinases; Glyburide; Guanylate Cyclase; | 2011 |
Antinociceptive and anti-hyperglycemic activity of methanol leaf extract of Cyperus scariosus.
Topics: Acetic Acid; Analgesics; Animals; Aspirin; Cyperus; Dose-Response Relationship, Drug; Glucose Tolera | 2011 |
Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K(+) channels pathway in the systemic antinociception of flavokawin B.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flav | 2011 |
Effect of glibenclamide on antinociceptive effects of antidepressants of different classes.
Topics: Amitriptyline; Analgesics; Analysis of Variance; Animals; Antidepressive Agents; Drug Interactions; | 2011 |
Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats.
Topics: 4-Aminopyridine; Adenosine; Adenosine Triphosphate; Animals; Glyburide; Humans; Hyperalgesia; Inject | 2011 |
Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats.
Topics: Animals; Behavior, Animal; Bradykinin; Diazoxide; Ganglia, Spinal; Glyburide; Ion Channel Gating; KA | 2011 |
Anti-hyperglycemic and antinociceptive activity of methanol leaf and stem extract of Nypa fruticans Wurmb.
Topics: Acetic Acid; Analgesics; Animals; Arecaceae; Aspirin; Blood Glucose; Glucose; Glyburide; Hyperglycem | 2011 |
The antinociceptive effects of JWH-015 in chronic inflammatory pain are produced by nitric oxide-cGMP-PKG-KATP pathway activation mediated by opioids.
Topics: Analgesics; Analgesics, Opioid; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagon | 2011 |
Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway.
Topics: Acetic Acid; Administration, Oral; Animals; Asteraceae; Carbazoles; Cyclic GMP-Dependent Protein Kin | 2012 |
The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats.
Topics: Acute Pain; Analgesics, Opioid; Animals; Chemical and Drug Induced Liver Injury; Diazoxide; Disease | 2013 |
Effect of diabetes on pinacidil-induced antinociception in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glyburide; Injections, I | 2002 |
Mechanisms involved in the antinociception caused by compound MV8612 isolated from Mandevilla velutina in mice.
Topics: Analgesics; Animals; Apamin; Bradykinin; Capsaicin; Charybdotoxin; Formaldehyde; Glyburide; Glycosid | 2003 |
ATP-sensitive potassium channels in rat primary afferent neurons: the effect of neuropathic injury and gabapentin.
Topics: Acetates; Amines; Animals; ATP-Binding Cassette Transporters; Basal Ganglia; Cyclohexanecarboxylic A | 2003 |
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib.
Topics: Analgesics; Animals; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship | 2005 |
Antinociceptive effect of leaf essential oil from Croton sonderianus in mice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Capsaicin; Croton; Disease Models, Animal; Dose- | 2005 |
Pharmacological evidence for the activation of Ca2+-activated K+ channels by meloxicam in the formalin test.
Topics: 4-Aminopyridine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Apamin; Behavior, Animal; | 2005 |
Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analgesics; Animals; Cyclic GMP; Formaldehyde; Glyburide; Injec | 2005 |
The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin.
Topics: Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Pro | 2006 |
Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Capsaicin; Coloring Agents; Enzyme Inhibi | 2006 |
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
Topics: Adenosine Triphosphate; Analgesia; Analgesics; Animals; Arginine; Bucladesine; Carbazoles; Cells, Cu | 2006 |
Role of nitric oxide/cyclic GMP/K(+) channel pathways in the antinociceptive effect caused by 2,3-bis(mesitylseleno)propenol.
Topics: Analgesics; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Formaldehyde; G | 2007 |
Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclophosphamide; Cysti | 2007 |
Lack of glibenclamide or TEA affinity for opioid receptors: further evidence for in vivo modulation of antinociception at K+ channels.
Topics: Amino Acid Sequence; Animals; Glyburide; Male; Molecular Sequence Data; Pain; Potassium Channel Bloc | 1994 |
Endogenous opioids and ATP-sensitive potassium channels are involved in the mediation of apomorphine-induced antinociception at the spinal level: a behavioral study in rats.
Topics: Adenosine Triphosphate; Animals; Apomorphine; Dopamine Agonists; Endorphins; Female; Glyburide; Inje | 1998 |
ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine | 1999 |
Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Analgesics; Animals; Apamin; Cesium; Charybdotoxin; Dibutyr | 2001 |
Participation of the nitric oxide-cyclic GMP-ATP-sensitive K(+) channel pathway in the antinociceptive action of ketorolac.
Topics: Adenosine Triphosphate; Analgesics; Animals; Behavior, Animal; Cyclic AMP; Dose-Response Relationshi | 2001 |
Pharmacological evidence for the activation of K(+) channels by diclofenac.
Topics: 4-Aminopyridine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; A | 2002 |