gallic acid and Obesity
gallic acid has been researched along with Obesity in 25 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Of interest is gallic acid, a trihydroxybenzoic acid that has progressively demonstrated robust anti-obesity capabilities in various experimental models." | 8.98 | Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid. ( Dludla, PV; Jack, B; Louw, J; Mazibuko-Mbeje, SE; Mkandla, Z; Mutize, T; Nkambule, BB; Orlando, P; Silvestri, S; Tiano, L, 2018) |
| " officinalis fruit juice and gallic acid facilitated their glucose homeostasis; improved insulin sensitivity; reduced obesity; abridged elevated blood pressure and declined cholesterol level, and also induced adipogenesis in 3T3-L1 adipocytes." | 7.96 | Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling. ( Bakrania, AK; Patel, SS; Variya, BC, 2020) |
| "The antiobesity effects of Chinese black tea (Pu-erh tea) and of gallic acid (GA) were investigated using in vitro and in vivo assays." | 7.78 | Antiobesity effects of Chinese black tea (Pu-erh tea) extract and gallic acid. ( Fujita, H; Hou, IC; Oi, Y; Yazawa, K, 2012) |
| "Gallic acid (GA) is a triphenolic compound with beneficial biological activities including anti-inflammatory, antidiabetic, antihypertensive, and antioxidant effects." | 5.91 | Gallic acid as a Sestrin (SESN2) activator and potential obesity therapeutic agent: A molecular docking study. ( Aguilar, CM; de Paula, AMB; Guimarães, ALS; Lescano, CH; Pires de Oliveira, I; Queiroz, LDRP; Santos, SHS; Sousa, JN, 2023) |
| "Syringic acid (SA) is a phenolic compound present in the fruit of the assai palm, Euterpe oleracea, and in the mycelium of the shiitake mushroom, Lentinula edodes." | 5.62 | Dietary syringic acid reduces fat mass in an ovariectomy-induced mouse model of obesity. ( Homma, Y; Iwamoto, K; Kawaguchi, N; Moriyama, T; Shirasaka, N; Suzuki, T; Tanaka, T; Wada, M; Yano, E, 2021) |
| "Hyperlipidemia is the major risk factors of heart disease such as atherosclerosis, stroke, and death." | 5.35 | Comparison of hypolipidemic activity of synthetic gallic acid-linoleic acid ester with mixture of gallic acid and linoleic acid, gallic acid, and linoleic acid on high-fat diet induced obesity in C57BL/6 Cr Slc mice. ( Jang, A; Jo, C; Lee, JW; Lee, M; Lee, NY; Song, HP; Srinivasan, P, 2008) |
| " Of interest is gallic acid, a trihydroxybenzoic acid that has progressively demonstrated robust anti-obesity capabilities in various experimental models." | 4.98 | Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid. ( Dludla, PV; Jack, B; Louw, J; Mazibuko-Mbeje, SE; Mkandla, Z; Mutize, T; Nkambule, BB; Orlando, P; Silvestri, S; Tiano, L, 2018) |
| " officinalis fruit juice and gallic acid facilitated their glucose homeostasis; improved insulin sensitivity; reduced obesity; abridged elevated blood pressure and declined cholesterol level, and also induced adipogenesis in 3T3-L1 adipocytes." | 3.96 | Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling. ( Bakrania, AK; Patel, SS; Variya, BC, 2020) |
| "This study investigated the influence of caffeic, ferulic, gallic and protocatechuic acids on high-fructose diet-induced metabolic syndrome in rats." | 3.88 | Dietary phenolic acids reverse insulin resistance, hyperglycaemia, dyslipidaemia, inflammation and oxidative stress in high-fructose diet-induced metabolic syndrome rats. ( Ajiboye, TO; Ibitoye, OB, 2018) |
| "Gallic acid (GA), a naturally abundant plant phenolic compound in vegetables and fruits, has been shown to have potent anti-oxidative and anti-obesity activity." | 3.80 | Gallic acid ameliorated impaired glucose and lipid homeostasis in high fat diet-induced NAFLD mice. ( Chao, J; Cheng, HY; Hsieh, MT; Huo, TI; Lee, MS; Liao, JW; Pao, LH; Peng, WH; Qin, XM; Tsai, JC, 2014) |
| "The antiobesity effects of Chinese black tea (Pu-erh tea) and of gallic acid (GA) were investigated using in vitro and in vivo assays." | 3.78 | Antiobesity effects of Chinese black tea (Pu-erh tea) extract and gallic acid. ( Fujita, H; Hou, IC; Oi, Y; Yazawa, K, 2012) |
| "Weight loss was 1." | 2.72 | Safety and efficacy of NT, an herbal supplement, in treating human obesity. ( Amen, RJ; Greenway, FL; Kai-yuan, W; Liu, Z; Martin, CK; Nofziger, J; Rood, JC; Yu, Y, 2006) |
| "Obesity is currently the most common cause of metabolic diseases including type 2 diabetes and hyperlipidemia." | 1.72 | Inhibitory Effects of Hydrolysable Tannins on Lipid Accumulation in 3T3-L1 Cells. ( Kaneko, H; Kishikawa, Y; Koike, Y; Nobushi, Y; Shimba, S; Uchiyama, T; Wada, T, 2022) |
| "Obesity is the leading risk factor for developing metabolic (dysfunction)-associated fatty liver disease (MAFLD)." | 1.72 | Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice. ( Aubourg, SP; Barriga, A; Dovale-Rosabal, G; Espinosa, A; Palomino-Calderón, A; Rodríguez, A; Romero, N; Troncoso, RH, 2022) |
| "Syringic acid (SA) is a phenolic compound present in the fruit of the assai palm, Euterpe oleracea, and in the mycelium of the shiitake mushroom, Lentinula edodes." | 1.62 | Dietary syringic acid reduces fat mass in an ovariectomy-induced mouse model of obesity. ( Homma, Y; Iwamoto, K; Kawaguchi, N; Moriyama, T; Shirasaka, N; Suzuki, T; Tanaka, T; Wada, M; Yano, E, 2021) |
| " This study indicated the potential of phospholipids in promoting the bioavailability of EGCG3''Me and might contribute to the production of functional food with better tea catechins absorption." | 1.51 | The regulation effect of EGCG3''Me phospholipid complex on gut flora of a high-fat diet-induced obesity mouse model. ( Cheng, L; Lin, Y; Yang, H; Zhang, X, 2019) |
| "Hyperlipidemia is the major risk factors of heart disease such as atherosclerosis, stroke, and death." | 1.35 | Comparison of hypolipidemic activity of synthetic gallic acid-linoleic acid ester with mixture of gallic acid and linoleic acid, gallic acid, and linoleic acid on high-fat diet induced obesity in C57BL/6 Cr Slc mice. ( Jang, A; Jo, C; Lee, JW; Lee, M; Lee, NY; Song, HP; Srinivasan, P, 2008) |
| "Gallic acid (GA) is a naturally abundant plant phenolic compound in the human diet and is known to reduce the risk of disease." | 1.34 | Effect of gallic acid on high fat diet-induced dyslipidaemia, hepatosteatosis and oxidative stress in rats. ( Hsu, CL; Yen, GC, 2007) |
Research
Studies (25)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 14 (56.00) | 24.3611 |
| 2020's | 7 (28.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Kato, E | 1 |
| Yama, M | 1 |
| Nakagomi, R | 1 |
| Shibata, T | 1 |
| Hosokawa, K | 1 |
| Kawabata, J | 1 |
| Tanaka, T | 1 |
| Iwamoto, K | 1 |
| Wada, M | 1 |
| Yano, E | 1 |
| Suzuki, T | 1 |
| Kawaguchi, N | 1 |
| Shirasaka, N | 1 |
| Moriyama, T | 1 |
| Homma, Y | 1 |
| Ahn, D | 1 |
| Kim, J | 1 |
| Nam, G | 1 |
| Zhao, X | 1 |
| Kwon, J | 1 |
| Hwang, JY | 1 |
| Kim, JK | 1 |
| Yoon, SY | 1 |
| Chung, SJ | 1 |
| Nobushi, Y | 1 |
| Wada, T | 1 |
| Koike, Y | 1 |
| Kaneko, H | 1 |
| Shimba, S | 1 |
| Uchiyama, T | 1 |
| Kishikawa, Y | 1 |
| Dovale-Rosabal, G | 3 |
| Espinosa, A | 3 |
| Rodríguez, A | 3 |
| Barriga, A | 3 |
| Palomino-Calderón, A | 3 |
| Romero, N | 3 |
| Troncoso, RH | 3 |
| Aubourg, SP | 3 |
| Sousa, JN | 2 |
| Queiroz, LDRP | 1 |
| de Paula, AMB | 2 |
| Guimarães, ALS | 2 |
| Lescano, CH | 1 |
| Aguilar, CM | 1 |
| Pires de Oliveira, I | 1 |
| Santos, SHS | 2 |
| Paraíso, AF | 1 |
| Andrade, JMO | 1 |
| Mangabeira, ES | 1 |
| Lelis, DF | 1 |
| Martins, AMEB | 1 |
| Lima, WJN | 1 |
| Melo, GA | 1 |
| Schwarz, M | 1 |
| Song, M | 1 |
| Yang, G | 1 |
| Hoa, TQ | 1 |
| Hieu, HD | 1 |
| Amin, ASM | 1 |
| Choe, W | 1 |
| Kang, I | 1 |
| Kim, SS | 1 |
| Ha, J | 1 |
| Pascual-Serrano, A | 1 |
| Arola-Arnal, A | 1 |
| Suárez-García, S | 1 |
| Bravo, FI | 1 |
| Suárez, M | 1 |
| Arola, L | 1 |
| Bladé, C | 1 |
| Henning, SM | 1 |
| Yang, J | 1 |
| Hsu, M | 1 |
| Lee, RP | 1 |
| Grojean, EM | 1 |
| Ly, A | 1 |
| Tseng, CH | 1 |
| Heber, D | 1 |
| Li, Z | 1 |
| Ibitoye, OB | 1 |
| Ajiboye, TO | 1 |
| Zhang, X | 3 |
| Chen, Y | 1 |
| Zhu, J | 1 |
| Zhang, M | 1 |
| Ho, CT | 1 |
| Huang, Q | 1 |
| Cao, J | 2 |
| Dludla, PV | 1 |
| Nkambule, BB | 1 |
| Jack, B | 1 |
| Mkandla, Z | 1 |
| Mutize, T | 1 |
| Silvestri, S | 1 |
| Orlando, P | 1 |
| Tiano, L | 1 |
| Louw, J | 1 |
| Mazibuko-Mbeje, SE | 1 |
| Variya, BC | 1 |
| Bakrania, AK | 1 |
| Patel, SS | 1 |
| Lin, Y | 1 |
| Cheng, L | 1 |
| Yang, H | 1 |
| Chao, J | 1 |
| Huo, TI | 1 |
| Cheng, HY | 1 |
| Tsai, JC | 1 |
| Liao, JW | 1 |
| Lee, MS | 1 |
| Qin, XM | 1 |
| Hsieh, MT | 1 |
| Pao, LH | 1 |
| Peng, WH | 1 |
| Doan, KV | 1 |
| Ko, CM | 1 |
| Kinyua, AW | 1 |
| Yang, DJ | 1 |
| Choi, YH | 1 |
| Oh, IY | 1 |
| Nguyen, NM | 1 |
| Ko, A | 1 |
| Choi, JW | 1 |
| Jeong, Y | 1 |
| Jung, MH | 1 |
| Cho, WG | 1 |
| Xu, S | 1 |
| Park, KS | 1 |
| Park, WJ | 1 |
| Choi, SY | 1 |
| Kim, HS | 1 |
| Moh, SH | 1 |
| Kim, KW | 1 |
| Ham, JR | 1 |
| Lee, HI | 1 |
| Choi, RY | 1 |
| Sim, MO | 1 |
| Seo, KI | 1 |
| Lee, MK | 1 |
| Cheng, M | 1 |
| Miao, Y | 1 |
| Wu, Z | 1 |
| Weng, P | 1 |
| Jang, A | 1 |
| Srinivasan, P | 1 |
| Lee, NY | 1 |
| Song, HP | 1 |
| Lee, JW | 1 |
| Lee, M | 1 |
| Jo, C | 1 |
| Skrzypczak-Jankun, E | 1 |
| Jankun, J | 1 |
| Oi, Y | 1 |
| Hou, IC | 1 |
| Fujita, H | 1 |
| Yazawa, K | 1 |
| Zielińska-Przyjemska, M | 1 |
| Dobrowolska-Zachwieja, A | 1 |
| Greenway, FL | 1 |
| Liu, Z | 1 |
| Martin, CK | 1 |
| Kai-yuan, W | 1 |
| Nofziger, J | 1 |
| Rood, JC | 1 |
| Yu, Y | 1 |
| Amen, RJ | 1 |
| Hsu, CL | 1 |
| Yen, GC | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Spirulina Platensis Supplementation and Calorie Restriction on Anthropometric, Body Composition, Lipid Profiles, Insulin Resistance, Stress Oxidative Biomarkers In Obese Men: A Randomized Controlled Trial Protocol Study[NCT06076161] | 32 participants (Actual) | Interventional | 2023-10-17 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
1 review available for gallic acid and Obesity
| Article | Year |
|---|---|
Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid.
Topics: Adipokines; Adipose Tissue; Animals; Cytokines; Diet; Fruit; Gallic Acid; Humans; Inflammation; Insu | 2018 |
Trials
1 trial available for gallic acid and Obesity
| Article | Year |
|---|---|
Safety and efficacy of NT, an herbal supplement, in treating human obesity.
Topics: Adolescent; Adult; Anthraquinones; Appetite Depressants; Body Mass Index; Dietary Supplements; Dose- | 2006 |
Other Studies
23 other studies available for gallic acid and Obesity
| Article | Year |
|---|---|
Substrate-like water soluble lipase inhibitors from Filipendula kamtschatica.
Topics: Animals; Butyrates; Enzyme Inhibitors; Filipendula; Glycosides; Lipase; Obesity; Pancreas; Plant Ext | 2012 |
Dietary syringic acid reduces fat mass in an ovariectomy-induced mouse model of obesity.
Topics: Animals; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Female; Gallic Acid; Humans; Mice; | 2021 |
Ethyl Gallate Dual-Targeting PTPN6 and PPARγ Shows Anti-Diabetic and Anti-Obese Effects.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, T | 2022 |
Inhibitory Effects of Hydrolysable Tannins on Lipid Accumulation in 3T3-L1 Cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; Cell Differen | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice.
Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Gallic Acid; Glycerides; Liver D | 2022 |
Gallic acid as a Sestrin (SESN2) activator and potential obesity therapeutic agent: A molecular docking study.
Topics: Animals; Antioxidants; Gallic Acid; Mammals; Molecular Docking Simulation; Obesity; Sestrins | 2023 |
Oral gallic acid improves metabolic profile by modulating SIRT1 expression in obese mice brown adipose tissue: A molecular and bioinformatic approach.
Topics: Adipose Tissue, Brown; Animals; Computational Biology; Diet, High-Fat; Gallic Acid; Gene Expression | 2019 |
Anti-obesity Effect of Fermented Persimmon Extracts via Activation of AMP-Activated Protein Kinase.
Topics: 3T3-L1 Cells; Abdominal Fat; Adipocytes; AMP-Activated Protein Kinases; Animals; Blood Glucose; Body | 2020 |
Grape seed proanthocyanidin supplementation reduces adipocyte size and increases adipocyte number in obese rats.
Topics: Adipocytes; Adiposity; Animals; Antioxidants; Disease Models, Animal; Fatty Acid-Binding Proteins; G | 2017 |
Decaffeinated green and black tea polyphenols decrease weight gain and alter microbiome populations and function in diet-induced obese mice.
Topics: Animals; Bacteria; Body Composition; Diet, High-Fat; DNA, Bacterial; Gallic Acid; Gastrointestinal M | 2018 |
Dietary phenolic acids reverse insulin resistance, hyperglycaemia, dyslipidaemia, inflammation and oxidative stress in high-fructose diet-induced metabolic syndrome rats.
Topics: Animals; Anti-Obesity Agents; Antioxidants; Biomarkers; Caffeic Acids; Coumaric Acids; Cytokines; Di | 2018 |
Metagenomics Analysis of Gut Microbiota in a High Fat Diet-Induced Obesity Mouse Model Fed with (-)-Epigallocatechin 3-O-(3-O-Methyl) Gallate (EGCG3″Me).
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Gallic Acid; Gastrointestinal Microbiome; Male; Met | 2018 |
Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling.
Topics: 3T3-L1 Cells; Adipogenesis; Animals; Diabetes Mellitus, Experimental; Fruit and Vegetable Juices; Ga | 2020 |
The regulation effect of EGCG3''Me phospholipid complex on gut flora of a high-fat diet-induced obesity mouse model.
Topics: Animals; Bacteria; Camellia sinensis; Diet, High-Fat; Disease Models, Animal; Gallic Acid; Gastroint | 2019 |
Gallic acid ameliorated impaired glucose and lipid homeostasis in high fat diet-induced NAFLD mice.
Topics: Animals; Diet, High-Fat; Gallic Acid; Glucose; Homeostasis; Hypercholesterolemia; Insulin Resistance | 2014 |
Gallic acid regulates body weight and glucose homeostasis through AMPK activation.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Blood Glucose; Body Weight; Dietary Fats; Enzyme | 2015 |
Anti-steatotic and anti-inflammatory roles of syringic acid in high-fat diet-induced obese mice.
Topics: Animals; Anti-Inflammatory Agents; Diet, High-Fat; Fatty Liver; Gallic Acid; Humans; Insulin; Interl | 2016 |
The modulatory effect of (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3″Me) on intestinal microbiota of high fat diet-induced obesity mice model.
Topics: Adult; Animals; Bacteroidetes; Diet, High-Fat; Disease Models, Animal; DNA, Bacterial; Feces; Female | 2017 |
Comparison of hypolipidemic activity of synthetic gallic acid-linoleic acid ester with mixture of gallic acid and linoleic acid, gallic acid, and linoleic acid on high-fat diet induced obesity in C57BL/6 Cr Slc mice.
Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Cell Nucleus; Cholesterol, HDL; Cholesterol, LDL; | 2008 |
Theaflavin digallate inactivates plasminogen activator inhibitor: could tea help in Alzheimer's disease and obesity?
Topics: Alzheimer Disease; Biflavonoids; Catechin; Electrophoresis, Polyacrylamide Gel; Gallic Acid; Humans; | 2010 |
Antiobesity effects of Chinese black tea (Pu-erh tea) extract and gallic acid.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Body Weight; Caffeine; Corn Oil; Diet, High-Fat; Dose- | 2012 |
[Effect of tea polyphenols on oxidative metabolism of polymorphonuclear neutrophils in healthy and obese people].
Topics: Adult; Antioxidants; Biflavonoids; C-Reactive Protein; Case-Control Studies; Catechin; Female; Flavo | 2005 |
Effect of gallic acid on high fat diet-induced dyslipidaemia, hepatosteatosis and oxidative stress in rats.
Topics: Adipose Tissue; Animals; Dietary Fats; Dyslipidemias; Fatty Liver; Gallic Acid; Leptin; Male; Obesit | 2007 |