folic acid and Aging
folic acid has been researched along with Aging in 378 studies
Research
Studies (378)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (12.96) | 18.7374 |
| 1990's | 52 (13.76) | 18.2507 |
| 2000's | 161 (42.59) | 29.6817 |
| 2010's | 91 (24.07) | 24.3611 |
| 2020's | 25 (6.61) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Cai, K; Gao, Y; Huang, G; Li, W; Li, Z; Luo, S; Sun, Y; Yan, J; Zhou, D | 1 |
| Kenny, RA; Laird, E; Molloy, AM; O'Connor, D; O'Halloran, AM | 1 |
| Dong, C; Huang, G; Li, W; Li, Z; Qian, Z; Sun, Y; Wang, Z; Zhang, D; Zhao, J; Zhou, D | 1 |
| Everson, TM; Ford, JB; Gaskins, AJ; Hauser, R; Hood, RB; Knight, AK; Smith, AK | 1 |
| Cao, XP; Tan, L; Wang, ZT; Xu, W; Yu, JT | 1 |
| Chang, YM; Chiu, PL; Ho, TJ; Huang, CY; Huang, RS; Ju, DT; Kuo, WW; Padma, VV; Su, YC; Tsai, BC; Yao, CH | 1 |
| Blake, GET; Hall, J; Petkovic, GE; Watson, ED | 1 |
| Bartoszek, AB; Kocka, KH; Kocki, T; Nowicki, GJ; Panasiuk, L; Rudnicka-Drożak, EA; Ślusarska, BJ | 1 |
| Al-Turki, MA; Barker, ME; Boston, PF; McKirdy, SJ; Russell, JM | 1 |
| Chang, H; Huang, G; Li, W; Lv, X; Wang, X; Wang, Y; Wilson, JX; Zhou, D | 1 |
| Praveen, G; Reddy, GB; Shalini, T; Sivaprasad, M | 1 |
| Adams, AA; Barker, VD; Betancourt, A; Harris, PA; Ireland, JL; McMurry, KE; Moffett-Krotky, AD; Reedy, SE; Siard-Altman, MH | 1 |
| Grosso, G | 1 |
| Carey, D; Clarke, R; Kenny, RA; Laird, EJ; Molloy, AM; O'Connor, DMA; O'Halloran, AM | 1 |
| Bičíková, M; Fiala, V; Flegr, J; Hlaváčová, J; Kaňková, Š; Máčová, L; Sýkorová, K | 1 |
| Bross, P; Carlsen, J; Dipace, G; Gregersen, N; Mosegaard, S; Olsen, RKJ | 1 |
| Jungert, A; Neuhäuser-Berthold, M; Zenke-Philippi, C | 1 |
| Baccarelli, AA; Boyer, EW; Colicino, E; Gao, X; Nwanaji-Enwerem, JC; Schwartz, J; Vokonas, P; Wang, C | 1 |
| Alberto, JM; Bossenmeyer-Pourié, C; Daval, JL; Guéant, JL; Martin, N; Pourié, G; Umoret, R | 1 |
| Chen, P; Lin, JF; Ye, S; Zhou, X | 1 |
| Barichello, T; Bellettini-Santos, T; Budni, J; Campos, ACBF; Cassoma, RCS; da Luz, AP; da Silva, S; Garcez, ML; Medeiros, EB; Mina, F; Rempel, LCT; Schiavo, GL; Steckert, AV | 1 |
| Batista-Silva, H; Bellettini-Santos, T; Budni, J; Canever, L; da Luz, AP; Garcez, ML; Ghisi Frassetto, AZ; Medeiros, EB; Mina, F; Ribeiro, FM; Schiavo, GL; Zabot, GC; Zugno, AI | 1 |
| Naito, S; Nishimura, T; Sasaki, A; Takano, T; Yoo, SK | 1 |
| Dai, C; Fei, Y; Li, J; Shi, Y; Yang, X | 1 |
| Huang, G; Li, W; Liu, H; Luo, S; Lv, X; Wang, Y; Zhou, D | 1 |
| Chen, Y; Huang, G; Li, W; Li, Z; Liu, H; Qian, Z; Sun, Y; Wilson, JX; Zhang, D; Zhao, J; Zhou, D | 1 |
| Cooper, BR; Hall, H; Mosley, AL; Qi, G; Weake, VM; Wijeratne, AB | 1 |
| Guallar-Castillón, P; Lana, A; Lopez-Garcia, E; Rodríguez-Artalejo, F; Struijk, EA | 1 |
| Adams, AN; Cramer, MN; Crandall, CG; Gagnon, D; Jaffery, MF; Kouda, K; Moralez, G; Romero, SA | 1 |
| Day, RS; Luo, ST; Pettee Gabriel, K; Simonsick, EM; Vidoni, ML | 1 |
| Bhat, JA; Dar, NJ; Gupta, AP; Hamid, A; Kaur, J; Najar, RA; Rahat, B; Wani, NA | 1 |
| Bodis, M; Geisel, J; Graeber, S; Hübner, U; Obeid, R | 1 |
| Granic, A; Hill, TR; Jagger, C; Martin-Ruiz, C; Mathers, JC; Mendonça, N; Seal, CJ | 1 |
| Arning, E; Bottiglieri, T; Hoffman, A; Qian, H; Sontag, E; Sontag, JM; Taleski, G; Wasek, B | 1 |
| Carey, D; Kenny, RA; Laird, EJ; Molloy, AM; O'Connor, D; O'Halloran, AM | 1 |
| Nollens, HH; Robeck, TR; Schmitt, TL; Tang, KN | 1 |
| Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Ho, MK; Kaliman, P; Leclerc, D; Malysheva, O; Pallàs, M; Rozen, R | 1 |
| Barrow, TM; Bollati, V; Byun, HM; Corsi, S; Kuhnle, GGC; Mathers, JC; Sae-Lee, C | 1 |
| Basu, A; Bush, H; Ebersole, JL; Huja, PE; Lambert, J | 1 |
| Bjørnvad, CR; Grotmol, T; Jörundsson, E; Kristensen, AT; Nødtvedt, A; Seim-Wikse, T; Skancke, E | 1 |
| Casey, MC; Cunningham, C; Hoey, L; Hughes, CF; Laird, E; McCarroll, K; McNulty, H; Molloy, AM; Moore, K; O'Kane, M; Strain, JJ; Tracey, F; Ward, M | 1 |
| Abderrafi Benotmane, M; Baatout, S; Craenen, K; Verslegers, M | 1 |
| Au, C; Cabreiro, F; Cochemé, HM; Gems, D; Greene, ND; Leung, KY; Noori, T; Schuster, E; Vergara-Irigaray, N; Weinkove, D | 1 |
| Hoey, L; Hughes, CF; McNulty, H; Ward, M | 1 |
| Martey, J; Rajabally, YA | 1 |
| Albala, C; Dangour, AD; Lera, L; Sanchez, H; Uauy, R | 1 |
| Cho, E; Giovannucci, E; Kim, HJ; Rosner, B; Willett, WC | 1 |
| Ames, D; Boundy, K; Brodaty, H; Bush, AI; Carne, RP; Ellis, KA; Faux, NG; Mander, AG; Martins, RN; Masters, CL; Moore, EM; Rowe, CC; Szoeke, C; Watters, DA; Woodward, MC | 1 |
| Chavan-Gautam, P; Joshi, S; Kale, A; Randhir, K; Sable, P | 1 |
| Achón, M; Montero, A; Partearroyo, T; Úbeda, N; Varela-Moreiras, G | 1 |
| House, JD; Jing, M; Munyaka, PM; O, K; Rodriguez-Lecompte, JC; Tactacan, GB | 1 |
| Rogers, E; Shea, TB | 1 |
| Choi, JS; Choi, SW; Jeong, SK; Kim, BH; Kim, HN; Kweon, SS; Lee, YH; Nam, HS; Park, KS; Shin, MH | 1 |
| Cheng, D; Huang, C; Jiang, Y; Kong, H; Lu, H; Pang, W; Yang, H | 1 |
| Chang, NS; Chen, BH; Cheng, NW; Chu, CY; Fu, TF; Hsiao, TH; Kao, TT; Lee, GH | 1 |
| Bos, R; Manios, Y; Mavrogianni, C; Moschonis, G; Singh-Povel, C | 1 |
| Agrawal, A; Dubey, GP; Ilango, K; Karmakar, D; Kumari, R; Singh, GP; Singh, PK | 1 |
| Hu, J; Sahyoun, NR; Wang, B | 1 |
| Troen, AM | 1 |
| Araújo, JM; Araújo, JR; Borges, N; Keating, E; Martel, F | 1 |
| Božović, IB; Brajenović-Milić, B; Kapović, M; Stanković, A; Vraneković, J; Živković, M | 1 |
| Medina Escobar, P; Meier, DW; Nydegger, U; Risch, C; Risch, L; Risch, M; Sakem, B | 1 |
| Bacich, DJ; O'Keefe, DS; Rycyna, KJ | 1 |
| Brouwer-Brolsma, EM; Brug, J; de Groot, LC; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Sohl, E; Swart, KM; Uitterlinden, AG; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Schoor, NM; van Wijngaarden, JP; Zillikens, MC | 1 |
| Carreras, O; Díaz-Castro, J; Murillo, ML; Nogales, F; Ojeda, ML; Rua, RM | 1 |
| Akhoon, BA; Pandey, R; Pandey, S; Rathor, L; Srivastava, S | 1 |
| Bobak, M; Gardiner, J; Horvat, P; Jansen, E; Kubinova, R; Pajak, A; Peasey, A; Pikhart, H; Schöttker, B; Tamosiunas, A | 1 |
| Min, JY; Min, KB | 1 |
| Chetina, N; Cipinska, M; Helliwell, N; Jia, J; Lefebvre, J; Liang, Y; Maynard, CA; Raimundo, A; Richards, SA; Virk, B; Weinkove, D | 1 |
| Ahmad Najar, R; Hamid, A; Hussain, A; Kaur, J; Rahat, B; Thakur, S | 1 |
| Meydani, SN; Paul, L; Reginaldo, C; Sawaengsri, H; Selhub, J; Steluti, J; Wang, J; Wu, D | 1 |
| Rosenberg, IH; Selhub, J | 1 |
| Bank, A; Chen, J; Cooper, AJ; Feola, J; Goligorsky, MS; Johnson, GV; Lin, CH; Pihlajaniemi, TA; Ruotsalainen, HJ; Shein, J; Zhang, Z | 1 |
| Chalé, A; Chalé, C | 1 |
| Refsum, H; Smith, AD | 1 |
| Dror, Y; Ichelzon, I; Polyak, Z; Stern, F; Tal, S | 1 |
| Mc Auley, MT; Mooney, KM; Salcedo-Sora, JE | 1 |
| Alexander, LM; Greaney, JL; Kenney, WL; Stanhewicz, AE | 1 |
| De la Fuente Arrillaga, C; Delgado-Martínez, AD; Delgado-Rodríguez, M; Martínez-González, MA; Martínez-Ramírez, MJ; Palma Pérez, S | 1 |
| Choi, SW; Liu, Z; Mason, JB | 1 |
| Brouwer, IA; Clarke, R; Katan, MB; Verhoef, P; Winkels, RM | 1 |
| Rosenberg, IH | 1 |
| Smith, AD | 2 |
| de Benoist, B | 1 |
| Cascalheira, JF; Domingues, FC; Faria, MC; Parreira, MC; Viegas, AN | 1 |
| Green, R; Luchsinger, JA; Mayeux, R; Miller, J; Tang, MX | 1 |
| Fukuwatari, T; Shibata, K; Wada, H | 1 |
| de Groot, LC; Knoops, KT; Kromhout, D; Spiro, A; Tucker, KL; van Staveren, WA | 1 |
| Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J | 5 |
| Burdge, GC; Hanson, MA; Jackson, AA; Lillycrop, KA; Phillips, ES; Slater-Jefferies, JL | 1 |
| Colla, M; Endres, M; Kronenberg, G | 1 |
| Cagnacci, A; Cannoletta, M; Volpe, A | 1 |
| Choi, SW; Friso, S; Kim, KC | 1 |
| Burlutsky, G; Flood, VM; Gopinath, B; Mitchell, P; Wang, JJ; Wong, TY | 1 |
| Calevo, MG; Cotellessa, M; d'Annunzio, G; Giannattasio, A; Gianotti, D; Lorini, R; Minniti, G; Napoli, F | 1 |
| Corcoran, CD; Munger, RG; Nelson, C; Wengreen, HJ | 1 |
| Li, Y; Liu, Y; Richardson, B; Strickland, FM | 1 |
| Fenech, M | 1 |
| Allen, RH; Davey, A; Hausman, DB; Johnson, MA; Poon, LW; Stabler, SP | 1 |
| Flood, VM; Gopinath, B; McMahon, CM; Mitchell, P; Rochtchina, E | 1 |
| Cheng, DM; Huang, CY; Jiang, YG; Kong, HY; Pang, W; Yang, HP | 1 |
| Eckert, R; Herrmann, W; Kasoha, M; Kirsch, SH; Obeid, R | 1 |
| Ahtiluoto, S; Hooshmand, B; Kåreholt, I; Kivipelto, M; Laatikainen, T; Leiviskä, J; Rusanen, M; Soininen, H; Solomon, A; Winblad, B | 1 |
| Blusztajn, JK; Crivello, NA; Joseph, JA; Shukitt-Hale, B; Smith, DE | 1 |
| Breilmann, J; Brunner, C; Neuhäuser-Berthold, M; Pons-Kühnemann, J; Richter, M | 1 |
| Kanwar, SS; Nehru, B; Singh, R; Sood, PK | 1 |
| Grieger, JA; Nowson, CA | 1 |
| Ashley-Koch, AE; Jamerson, BD; Payne, ME; Potocky, CF; Speer, MC; Steffens, DC | 1 |
| Dwyer, JT; Jensen, GL; Johnson, MA; Miller, JW; Speakman, JR; Starke-Reed, P; Volpi, E | 1 |
| Beran-Praher, M; Fuchs, D; Haller, H; Leblhuber, F; Schroecksnadel, K; Steiner, K | 1 |
| Brown, B; Huang, MH; Kado, D; Karlamangla, A; Seeman, T | 1 |
| Ando, F; Nakashima, T; Shimokata, H; Sugiura, S; Uchida, Y | 1 |
| Apeland, T; Bates, CJ; Drabløs, PA; Hervig, T; Mansoor, MA; Stakkestad, JA; Wentzel-Larsen, T | 1 |
| Arendell, L; Chen, Z; Neuhouser, ML; Snetselaar, LG; Stanaway, JD; Stefanick, ML; Thomson, CA | 1 |
| Firbank, MJ; Ford, GA; Hansrani, M; Harrington, F; McKeith, IG; Narayan, SK; O'Brien, JT; Saxby, BK; Stansby, G | 1 |
| de Groot, RH; Durga, J; Jolles, J; Kok, FJ; Schiepers, OJ; van Boxtel, MP; Verhoef, P | 1 |
| Liu, GP; Liu, YH; Mousseau, DD; Tian, Q; Wang, JZ; Wang, Q; Wei, W; Wei, Z; Zhang, CE | 1 |
| Ames, D; Bush, AI; Ellis, KA; Faux, NG; Fowler, CJ; Laws, SM; Martins, RN; Masters, CL; Pertile, KK; Porter, L; Rembach, A; Rowe, CC; Rumble, RL; Szoeke, C; Taddei, K; Taddei, T; Trounson, BO; Villemagne, VL; Ward, V | 1 |
| Cabelof, DC; Patterson, D | 1 |
| Cavelaars, AE; de Groot, LC; Dhonukshe-Rutten, RA; Doets, EL; van 't Veer, P | 1 |
| Morris, MC | 1 |
| Alencar, VH; Carvalho Barbosa, Rde C; Freire, TF; Menezes, DC; Rabenhorst, SH; Sales, DC | 1 |
| Booth, CL; Hunter, DC; Kruger, MC; Loh, JM; Skinner, MA; Stevenson, LM; Wohlers, M; Wolber, FM | 1 |
| Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M | 1 |
| Casson, RI; Dodds, L; Ho, V; King, WD; Massey, TE; Perkins, SL | 1 |
| Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G | 1 |
| Hartman, TJ; Jensen, GL; Lawrence, FR; Maras, J; Mitchell, DC; Smiciklas-Wright, H; Still, CD; Tucker, KL | 1 |
| Alverson, PB; Ayling, JE; Bailey, SW; Boilson, A; Daly, L; Kelleher, CC; MacCooey, A; McDermott, AP; Scott, JM; Shirley, I; Shrivastava, A; Staines, A; Sweeney, MR | 1 |
| Blom, HJ; Farkas, M; Jessen, F; Linnebank, M; Popp, J; Semmler, A; Smith, DE; Smulders, YM | 1 |
| Gustafson, L; Hultberg, B; Nilsson, K | 3 |
| Blasko, I; Fischer, P; Heinz Tragl, K; Hinterberger, M; Jungwirth, S; Kemmler, G; Krampla, W; Leitha, T | 1 |
| Aung, KC; Feng, L; Ng, TP; Scherer, SC; Yap, KB | 1 |
| Almkvist, O; Persson, N; Viitanen, M; Wahlin, Å | 1 |
| House, JD; Jing, M; Munyaka, PM; O, K; Rodriguez-Lecompte, JC; Sharif, S; St Paul, M; Tactacan, G | 1 |
| Bertrais, S; de Courcy, GP; Ducros, V; Favier, A; Franchisseur, C; Galan, P; Guilland, JC; Hercberg, S; Maurel, M; Mennen, LI; Nicolas, JP; Zarebska, M | 1 |
| Grodstein, F; Stampfer, MJ | 1 |
| Mattson, MP; Shea, TB | 1 |
| Mattson, MP | 1 |
| Friis, H; Gomo, E; Kaestel, P; Ndhlovu, PD; Nyazema, NZ; Vennervald, BJ | 1 |
| Ganji, V; Kafai, MR | 3 |
| Bailey, LB; Gregory, JF; Herrlinger-Garcia, K; Kauwell, GP; Theriaque, DW; Wolfe, JM | 1 |
| Bagley, PJ; Choi, SW; Dolnikowski, GG; Edmondson, AN; Friso, S; Mason, JB; Smith, DE | 1 |
| Gustafson, L; Hultberg, B; Isaksson, A; Nilsson, K | 1 |
| Balas, D; Bouzigon, E; Emeriau, JP; Parrot, F; Rainfray, M; Salles-Montaudon, N | 1 |
| Blom, AH; Bosma, H; de Bruijn, C; de Vente, J; Jolles, J; Steinbusch, HW; Teunissen, CE; Van Boxtel, MP; Wauters, BA | 1 |
| Debanne, SM; Friedland, RP; Jacobsen, DW; Lerner, AJ; Mizrahi, EH; Petot, GJ; Traore, F | 1 |
| Balamurugan, K; Said, HM | 1 |
| Allen, LH; Campbell, AK; Green, R; Haan, MN; Miller, JW | 1 |
| Choi, SW; Crott, JW; Ditelberg, JS; Mason, JB; Ordovas, JM | 1 |
| BONATI, B; NANI, S; RANCATI, GB | 1 |
| OERIU, S | 1 |
| OERIU, S; TANASE, I | 3 |
| WESTON, TE | 1 |
| OERIU, S; VERZAR, F | 1 |
| NYSTROEM, B | 1 |
| OERIU, S; TIGHECIU, M | 2 |
| SPIGAI, C | 1 |
| GEORGESCU, C | 1 |
| LEHNINGER, AL; VIGNAIS, PM; VIGNAIS, PV | 1 |
| BENESCH, H; CRACEA, M; OERIU, S | 1 |
| Anderson, C; Collura, J; Coyle, JT; Drager, U; Dunham, KS; Grier, A; Tsai, G | 1 |
| Chada, L; McGaw, J; Nakano, E; Powers, HJ; Taylor, CJ | 1 |
| Geisel, J; Herrmann, W; Obeid, R; Schorr, H | 1 |
| Kumar, R; Mihalick, SM; Ortiz, D; Rogers, E; Shea, TB | 1 |
| Allen, JC; Boyd, LC; Hoffman, M; Sauls, DL | 1 |
| Bergman, B; Nilsson-Ehle, H; Sjöstrand, J | 1 |
| Hahn, A; Ströhle, A; Wolters, M | 1 |
| Słowińska, MA; Wadołowska, L | 1 |
| Bakun, P; Dallal, GE; Olson, B; Rosenberg, IH; Selhub, J; Tucker, KL | 1 |
| Achón, M; Maestro de las Casas, C; Manzarbeitia, F; Pérez-Miguelsanz, J; Ramírez, C; Roncalés, M; Varela-Moreiras, G | 1 |
| Andersen, ML; Bignotto, M; D'Almeida, V; Martins, PJ; Santos, RF; Tufik, S | 1 |
| Barrera, G; Bunout, D; de la Maza, MP; Garrido, A; Gattas, V; Glasinovic, A; Hirsch, S; Leiva, L; Ronco, AM; Vasquez, M | 1 |
| Hartmann, B; Krems, C; Lührmann, PM; Neuhäuser-Berthold, M; Strassburg, A | 1 |
| Frick, B; Fuchs, D; Leblhuber, F; Neurauter, G; Schroecksnadel, K | 1 |
| Bryan, J; Calvaresi, E | 1 |
| Cheng, G; Kwok, T; Lai, WK; Pang, CP; Poon, P; Woo, J | 1 |
| Allen, LH; Green, R; Haan, MN; Miller, JW; Ramos, MI | 1 |
| Brzozowska, A; Roszkowski, W; Sicińska, E | 1 |
| Mathers, JC; McKay, JA; Williams, EA | 1 |
| Deary, IJ; Pattie, A; Starr, JM; Whalley, LJ; Whiteman, MC | 1 |
| Block, G; Eskenazi, B; Kidd, SA; Marks, AR; Sloter, E; Wyrobek, AJ | 1 |
| Huang, MH; Kado, DM; Karlamangla, AS; Rowe, JW; Seeman, TE; Selhub, J; Troen, A | 1 |
| Choi, SW; Friso, S; Keyes, MK; Mason, JB | 1 |
| Ito, T; Sakuta, H; Suzuki, T; Yasuda, H | 1 |
| Andria, G; Scala, I; Sebastio, G | 1 |
| Ali, SA; Iqbal, MP; Ishaq, M; Kazmi, KA; Khan, AH; Mehboobali, N; Waqar, MA; Yousuf, FA | 1 |
| Afman, L; Blom, HJ; den Heijer, M; Oppenraay-van Emmerzaal, D; Thomas, CM; van Beynum, IM | 1 |
| Bahari, B; Belshaw, NJ; Buckley, L; Elliott, GO; Johnson, IT; Mathers, JC; Williams, EA | 1 |
| Basu, T; Drager, KL; Field, CJ; Goruk, S; Van Aerde, A | 1 |
| Dainty, JR; de Meer, K; Finglas, PM; Jakobs, C; Kok, RM; Smith, DE; Smulders, YM; Stehouwer, CD | 1 |
| Bottiglieri, T; Diaz-Arrastia, R | 1 |
| Brunetti, N; Forti, P; Licastro, F; Maioli, F; Martelli, M; Porcellini, E; Ravaglia, G; Servadei, L | 1 |
| Qiao, N; Rosenberg, I; Scott, T; Spiro, A; Tucker, KL | 1 |
| Ross, CM | 1 |
| Choi, SW; Friso, S | 1 |
| de Craen, AJ; Frölich, M; Gussekloo, J; Jolles, J; Mooijaart, SP; Stott, DJ; Westendorp, RG | 1 |
| Forster, S; Gariballa, S | 3 |
| Andriollo-Sanchez, M; Azzini, E; Coudray, C; Ducros, V; Intorre, F; Maiani, G; Meunier, N; O'Connor, JM; Polito, A; Raguzzini, A; Roussel, AM | 1 |
| Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M | 1 |
| Choi, SW; Jang, H; Mason, JB | 1 |
| Allen, LH; Green, R; Haan, MN; Jagust, WJ; Miller, JW; Mungas, DM; Ramos, MI | 1 |
| Klich-Raczka, A; Mossakowska, M; Podkówka, R; Sawiński, K; Wieczorowska-Tobis, K; Zyczkowska, J | 1 |
| Borek, C | 1 |
| Arvanitidou, M; Makedou, A; Mavromichalis, I; Papandreou, D; Rousso, I | 2 |
| Carlsson, CM | 1 |
| Forster, S; Gariballa, S; Powers, H; Walters, S | 1 |
| Aggarwal, NT; Bienias, JL; Evans, DA; Morris, MC; Schneider, JA; Tangney, CC | 1 |
| Abrams, SA; Chen, Z; Hicks, PD; Lönnerdal, B; Zavaleta, N | 1 |
| Dyer, CB; Goodwin, JS; Kala, G; Kelly, PA; Mathews Oliver, SA; Smith, SM; Zwart, SR | 1 |
| Födinger, M; Hubmann, M; Huemer, M; Krumpholz, R; Simma, B; Ulmer, H; Vonblon, K | 1 |
| Ellis, R; Hudson, P; McCaddon, A; McCracken, C | 1 |
| Chuah, L; Feng, L; Kua, EH; Ng, TP; Niti, M | 1 |
| Becker, G; Fassbender, K; Herrmann, W; Kasoha, M; Knapp, JP; Kostopoulos, P; Obeid, R | 1 |
| Anteunis, LJ; Durga, J; Kok, FJ; Schouten, E; Verhoef, P | 1 |
| Dobie, RA | 1 |
| Garrì, MT; Lucca, U; Nobili, A; Riva, E; Tettamanti, M | 1 |
| Aiello, AE; Allen, LH; Green, R; Haan, MN; Jagust, WJ; Miller, JW; Mungas, DM; Whitmer, RA | 1 |
| Elia, M; Guéant, JL; Romano, A | 1 |
| Anello, G; Benamghar, L; Bosco, P; Calabrese, S; Fontaine, T; Guéant, JL; Guéant-Rodriguez, RM; Romano, A; Spada, RS; Stella, G | 1 |
| Anello, G; Benamghar, L; Bosco, P; Calabrese, S; Castellano, A; Fajardo, A; Guéant, JL; Guéant-Rodriguez, RM; Lipari, L; Proto, C; Romano, A; Sirna, S; Spada, RS; Stella, G | 1 |
| Fernández, S; González, S; Huerta, JM; Lasheras, C; Patterson, AM | 1 |
| Reynolds, E | 1 |
| Choi, SW; Crott, JW; Friso, S; Jang, H; Keyes, MK; Liu, Z; Mason, JB; Smith, DE | 1 |
| Andriollo-Sanchez, M; Azzini, E; Catasta, G; Coudray, C; Ducros, V; Intorre, F; Maiani, G; Meunier, N; O'Connor, JM; Polito, A; Raguzzini, A; Roussel, AM; Toti, E; Zaccaria, M | 1 |
| Balk, E; Chew, P; Chung, M; DeVine, D; Ip, S; Lau, J; Raman, G; Tatsioni, A | 1 |
| Albers, U; Alder, M; Barrios, L; Castillo, MJ; Gonzalez-Gross, M; Pietrzik, K; Sola, R | 1 |
| Chou, YF; Huang, RF; Yu, CC | 1 |
| Breteler, MM; de Lau, LM; Johnston, C; Refsum, H; Smith, AD | 1 |
| Carroll, WD; Farrell, WE; Fryer, AA; Ismail, KM; Nafee, TM | 1 |
| Johnson, MA | 1 |
| Barschak, AG; Matté, C; Netto, CA; Scherer, EB; Stefanello, FM; Vargas, CR; Wyse, AT | 1 |
| Fanghänel, J; Gedrange, T; Maile, S; Proff, P; Weingärtner, J | 1 |
| Brachet, P; Cardinault, N; Chanson, A; D'Incan, M; Martin, JF; Rock, E; Souteyrand, P | 1 |
| Bi, XH; Zhang, JW; Zhang, ZX; Zhao, HL | 1 |
| Colcombe, SJ; Erickson, KI; Kramer, AF; McAuley, E; Prakash, RS; Suever, BL | 1 |
| Kim, YI; Kotsopoulos, J; Sohn, KJ | 1 |
| Chan, A; Graves, V; Rozen, R; Shea, TB; Tchantchou, F | 1 |
| Holden, JT; Utech, NM | 1 |
| Cooperman, JM; Feldman, R; Gordon, M; Luhby, AL; Stone, ML | 1 |
| Lawrence, VA | 1 |
| Bailey, LB; Bloch, BS; Busby, MJ; Cerda, JJ; Chandler, CJ; Halsted, CH; Vargas, L | 1 |
| Maletta, GJ; Vatassery, GT | 1 |
| Robel, EJ | 1 |
| Bovina, C; Formiggini, G; Marchetti, M; Tolomelli, B | 1 |
| Freedman, ML | 1 |
| Domínguez, J; Ordóñez, LA | 1 |
| Poole, WE; Scott, KJ; Sharman, GB; Thompson, SY | 1 |
| Branda, RF | 1 |
| Bachevalier, J; Botez, MI | 1 |
| Ek, J; Magnus, E | 1 |
| Williams, WJ | 1 |
| Bisozzi, L; De Martino, A; Leoncini, R; Lorenzini, L; Marinello, E; Pagani, R; Pizzichini, M; Sorbellini, F; Terzuoli, L; Testi, W | 1 |
| Blonde-Cynober, F; Bories, PN; Cals, MJ; Coudray-Lucas, C; de Jaeger, C; Desveaux, N; Devanlay, M; Duche, JC; Luciani, L; Succari, M | 1 |
| Arlow, FL; Majumdar, AP; Nensey, YM | 1 |
| García-Cuevas, M; Pérez-Olleros, L; Ruiz-Roso, B; Varela-Moreiras, G | 1 |
| Jacques, PF; Rosenberg, IH; Rush, D; Selhub, J; Wilson, PW | 1 |
| Botez, MI; Joyal, CC; Lalonde, R | 1 |
| Dybkjaer, L; Lyngbak, M; Møller, J; Pedersen, AM; Rasmussen, K | 1 |
| Agudo, FR; Andrés, P; Gaspar, MJ; Jiménez, A; Mañas, LR; Ortega, RM; Pascual, T | 1 |
| Kokue, E; Natsuhori, M; Shimoda, M | 1 |
| Eberhardt, W; Heseker, H; Kübler, W; Schneider, R | 1 |
| Basu, TK; Quinn, K | 1 |
| Ferry, M; Haller, J; Lammi-Keefe, CJ; Weggemans, RM | 1 |
| Bäckman, L; Hill, RD; Wahlin, A; Winblad, B | 1 |
| Joosten, E; Lesaffre, E; Riezler, R | 1 |
| Arheart, K; Chaudhary, D; Dennis, V; Green, R; Gupta, A; Jacobsen, DW; Kutner, M; Mayer, EL; Robinson, K; Selhub, J; Vigo, P | 1 |
| Tett, SE; Triggs, EJ | 1 |
| Chiulli, SJ; Garry, PJ; Haaland, KY; Koehler, KM; La Rue, A; Wayne, SJ | 1 |
| Baumgartner, RN; Garry, PJ; Koehler, KM; Pareo-Tubbeh, SL; Romero, LJ | 1 |
| Grobbee, DE; Kok, FJ; Kruyssen, DA; Refsum, H; Schouten, EG; Ueland, PM; Verhoef, P; Witteman, JC | 1 |
| Goggins, M; Kelly, P; McPartlin, J; Scott, JM; Weir, DG | 1 |
| Edwards, SL; Ma, KN; Potter, JD; Schaffer, D; Slattery, ML | 1 |
| Aguayo, VM; Berger, J; Lujan, C; San Miguel, JL; Tellez, W; Traissac, P | 1 |
| Carmel, R | 1 |
| Nygård, O; Refsum, H; Ueland, PM; Vollset, SE | 1 |
| Bartels, PC; Peetoom, JJ; Schoorl, M | 1 |
| Artuch, R; Lambruschini, N; Moyano, D; Valls, C; Vilaseca, MA | 1 |
| Clarke, R; Frost, C; Khaw, KT; Refsum, H; Sherliker, P; Ueland, PM; Ulvik, A; Woodhouse, P | 1 |
| Erkkola, M; Järvinen, A; Karppinen, M; Knip, M; Virtanen, SM | 1 |
| Coakley, D; Keane, EM; Kelleher, B; O'Broin, S; Walsh, JB | 1 |
| Clarke, R; Jobst, KA; Refsum, H; Smith, AD; Sutton, L; Ueland, PM | 1 |
| Ubbink, JB | 1 |
| Dreosti, IE | 1 |
| Wilcken, B; Wilcken, DE | 1 |
| Ames, BN | 1 |
| Andrade Juguan, J; Lukito, W; Schultink, W | 1 |
| Berglund, L; Berne, C; Brattström, L; Refsum, H; Ueland, PM; Wollesen, F | 1 |
| Cutler, GM; Edmonds, JT; Gunter, EW; Houston, DK; Johnson, MA; Nozza, RJ; Shea, KJ | 1 |
| Martinasevic, MK; Miller, MW; Rios, GR; Tephly, TR | 1 |
| Bodis, M; Geisel, J; Herrmann, W; Quast, S; Schultze, H; Ullrich, M | 1 |
| Kasper, H | 1 |
| Cavaleri, A; Lazzara, S; Melita, G; Pergolizzi, FP; Riso, F; Tigano, D; Trovato, M | 1 |
| Hann, SK; Kim, SM; Kim, YK | 1 |
| Baggott, JE | 1 |
| Baumgartner, RN; Garry, PJ; Koehler, KM; LaRue, A; Liang, HC; Lindeman, RD; Romero, LJ | 1 |
| Markesbery, WR; Riley, KP; Smith, CD; Snowdon, DA; Tully, CL | 1 |
| Alexy, U; Kersting, M; Sichert-Hellert, W | 1 |
| Bernstein, MA; Clements, KM; Evans, WJ; Fiatarone Singh, MA; O'Neill, EF; Ryan, AD | 1 |
| Fernstrom, JD | 1 |
| Al Bahrani, I; Al-Salmy, HS; Deleu, D; Gravell, D; Hanssens, Y; Knox-MacAulay, H; Louon, A; Nam, D; Okereke, P; Sivagnanam, S; Sundaram, K | 1 |
| Berner, B; Odum, L; Parving, A | 1 |
| Bülow, I; Knudsen, N; Laurberg, P; Ovesen, L; Perrild, H; Rasmussen, LB | 1 |
| Delvin, EE; Genest, J; Lambert, M; Merouani, A; Rozen, R | 1 |
| Blumberg, JB; Dallal, G; McKay, DL; Perrone, G; Rasmussen, H | 1 |
| Caldarera, M; Cucinotta, D; Dalmonte, E; Forti, P; Grossi, G; Macini, P; Maioli, F; Ravaglia, G; Zanardi, V | 1 |
| Cherubini, A; Mecocci, P; Polidori, MC; Senin, U | 1 |
| Arakawa, K; Coetzee, GA; Lee, HP; Ong, CN; Saw, SM; Yu, MC; Yuan, JM | 1 |
| Bargossi, AM; Caldarera, M; Cavalli, G; Facchini, A; Forti, P; Franceschi, C; Grossi, G; Maioli, F; Mariani, E; Ravaglia, G; Vettori, C | 1 |
| Halsted, CH | 1 |
| Allen, RH; Baumgartner, RN; Garry, PJ; Koehler, KM; Rimm, EB; Stabler, SP | 1 |
| Dekou, V; Ebrahim, S; Gudnason, V; Humphries, SE; Lennon, L; Papacosta, O; Refsum, H; Ueland, PM; Whincup, P | 1 |
| Hoag, SW; Hussain, AS | 1 |
| Jones, GM; Narkewicz, MR; Thompson, HR | 1 |
| Archer, MC; Clarkson, TW; Strain, JJ | 1 |
| Bäckman, L; Robins Wahlin, TB; Wahlin , A; Winblad, B | 1 |
| Chylack, LT; Friend, J; Hankinson, SE; Jacques, PF; Khu, PM; Padhye, N; Rogers, G; Taylor, A; Tung, W; Willett, WC; Wolfe, JK | 1 |
| González-Gross, M; Marcos, A; Pietrzik, K | 1 |
| Naurath, HJ | 1 |
| Law, MR; Morris, JK; Wald, DS; Wald, NJ | 1 |
| Selhub, J | 1 |
| Dirren, H; Eussen, SJ; Ferry, M; Haller, J; Hininger, I; Matthys, C | 1 |
| Achon, M; Alonso-Aperts, E; Varela-Moreiras, G | 1 |
| Andrés, P; Bermejo, LM; Faci, M; Jiménez, A; Lolo, JM; Lopez-Sobaler, AM; Lozano, MC; Ortega, RM; Requejo, AM | 1 |
| Anderson, PH; Block, PC; Duell, PB; Evans, AA; Graf, EE; Hess, DL; Irvin-Jones, A; Kruger, WD; Malinow, MR; Upson, BM; Wang, L; Williams, MA | 1 |
| Buysschaert, M; Dramais, AS; Hermans, MP; Jamart, J; Wallemacq, P | 1 |
| Bates, CJ; Gregory, J; Mansoor, MA; Pentiev, K; Prentice, A | 1 |
| Berger, K; Collins, AR; Deary, IJ; Duthie, SJ; Leaper, S; Whalley, LJ | 1 |
| Deeg, DJ; Jelicic, M; Jonker, C | 1 |
| Duan, W; Kruman, II; Mattson, MP | 1 |
| Bryan, J; Calvaresi, E; Hughes, D | 1 |
| Choi, SW; Ghandour, H; Lin, BF; Mason, JB; Selhub, J | 1 |
| Reynolds, EH | 1 |
| Leeming, JT; Webster, SG | 1 |
| Jacob, F; Siddons, RC | 1 |
| Diculescu, I; Onicescu, D | 3 |
| Rodríguez, MS | 1 |
| Thornton, BP; Thornton, WE | 1 |
| Blackwell, LA; Grover, TA; Middaugh, LD; Zemp, JW | 1 |
| Andersson, A; Brattström, L; Hamfelt, A; Hultberg, B; Isaksson, A; Israelsson, B | 1 |
| Everman, BW; Koblin, DD | 1 |
| Albertini, RJ; Branda, RF; Jacobson-Kram, D; O'Neill, JP | 1 |
| Hancock, DD; Jacky, PB; Prieur, DJ; Stone, DM | 1 |
| Jacky, PB; Prieur, DJ; Stone, DM | 1 |
| Beard, ME; Duncan, JM; Gilchrist, NL; Hanger, HC; Sainsbury, R | 1 |
| Eger, EI; Koblin, DD; Lampe, GH; Tomerson, BW; Waldman, FM; Wauk, LZ | 1 |
| Bailey, LB | 1 |
| Koblin, DD; Tomerson, BW; Waldman, FM | 1 |
| Green, R | 1 |
| Horne, DW; Patterson, D; Said, HM | 1 |
| Girard, CL; Matte, JJ; Roy, GL | 1 |
| Bailey, LB; Cerda, JJ | 1 |
| MacDonald, DG | 1 |
| Freedman, ML; Grinblat, J; Hernandez, F; Marcus, DL | 1 |
| Brattström, LE; Hardebo, JE; Hultberg, BL | 1 |
| Kavlock, RJ; Rehnberg, BF; Rogers, EH | 1 |
| Caird, FI | 1 |
| Bhanthumnavin, K; Halsted, CH; Wright, JR | 1 |
| Werner, I | 1 |
| Theuer, RC | 1 |
| Reizenstein, P | 1 |
Reviews
49 review(s) available for folic acid and Aging
| Article | Year |
|---|---|
Sustaining an ageing population: the role of micronutrients in frailty and cognitive impairment.
Topics: Aged; Aging; Carotenoids; Cognitive Dysfunction; Folic Acid; Frailty; Humans; Longitudinal Studies; Micronutrients; Vitamins | 2023 |
Dietary Components and Nutritional Strategies for Dementia Prevention in the Elderly.
Topics: Aged; Aging; Animals; Dementia; Diet; Diet, Mediterranean; Folic Acid; Humans; Polyphenols | 2023 |
Riboflavin Deficiency-Implications for General Human Health and Inborn Errors of Metabolism.
Topics: Acyl-CoA Dehydrogenases; Aging; Animals; Diet; Electron Transport; Energy Metabolism; Fatty Acids; Female; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Genetic Variation; Homocysteine; Humans; Immune System; Metabolism, Inborn Errors; Mitochondria; Mutation; Phenotype; Pregnancy; Protein Folding; Riboflavin; Riboflavin Deficiency | 2020 |
A Novel Review of Homocysteine and Pregnancy Complications.
Topics: Abortion, Habitual; Aging; Birth Weight; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2021 |
An appraisal of folates as key factors in cognition and ageing-related diseases.
Topics: Aging; Cognition; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Humans; Neurodegenerative Diseases | 2020 |
Vitamin B12 and ageing: current issues and interaction with folate.
Topics: Aging; Animals; Biomarkers; Clinical Trials as Topic; Folic Acid; Food, Fortified; Humans; Metabolic Networks and Pathways; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Application of the Key Events Dose-response Framework to Folate Metabolism.
Topics: Aging; Dietary Supplements; Dose-Response Relationship, Drug; Enterocytes; Folic Acid; Food, Fortified; Homeostasis; Humans; Intestinal Mucosa; Kidney; Liver | 2016 |
Folates and aging: Role in mild cognitive impairment, dementia and depression.
Topics: Aged; Aging; Brain; Cognition; Cognitive Dysfunction; Dementia; Depression; Disease Progression; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Vitamin B Complex | 2015 |
Excessive folic acid intake and relation to adverse health outcome.
Topics: Aging; Base Sequence; Breast Neoplasms; Female; Folic Acid; Humans; Killer Cells, Natural; Neoplasm Proteins; Polymorphism, Genetic; Sequence Deletion; Tetrahydrofolate Dehydrogenase | 2016 |
Homocysteine, B Vitamins, and Cognitive Impairment.
Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
Computational modelling folate metabolism and DNA methylation: implications for understanding health and ageing.
Topics: Aging; Animals; Computer Simulation; DNA Methylation; Epigenesis, Genetic; Folic Acid; Health Status; Humans; Models, Biological | 2018 |
Other one-carbon micronutrients and age modulate the effects of folate on colorectal carcinogenesis.
Topics: Aging; Animals; Colorectal Neoplasms; Diet; DNA Methylation; Folic Acid; Humans; Micronutrients; Risk Factors; Vitamin B Complex; Wnt Proteins | 2008 |
Effects of folate and vitamin B12 on cognitive function in adults and the elderly.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Middle Aged; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
The worldwide challenge of the dementias: a role for B vitamins and homocysteine?
Topics: Aged; Aged, 80 and over; Aging; Dementia; Environment; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex | 2008 |
Folic acid, neurodegenerative and neuropsychiatric disease.
Topics: Aging; Alzheimer Disease; Animals; Brain; Clinical Trials as Topic; Dementia, Vascular; Depression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Neuronal Plasticity; Stroke; Vitamin B Complex | 2009 |
DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging.
Topics: Aging; Animals; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Female; Folic Acid; Genomic Imprinting; Humans; Longevity; Mice; Neoplasms; Pregnancy | 2009 |
Folate, DNA damage and the aging brain.
Topics: Aging; Animals; Brain; Cell Nucleus; Cytosine; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Methylation; Neurodegenerative Diseases; Rats; Reactive Oxygen Species; Risk Factors; S-Adenosylmethionine; Uracil | 2010 |
Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging.
Topics: Aging; Animals; DNA Polymerase beta; DNA Repair; Down Syndrome; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genomic Instability; Haploinsufficiency; Humans; Leukemia; MicroRNAs; Oxidative Stress; Phenotype | 2012 |
Nutritional determinants of cognitive aging and dementia.
Topics: Aging; Animals; Cognition Disorders; Dementia; Diet; Dietary Fats; Docosahexaenoic Acids; Folic Acid; Humans; Vitamin B 12; Vitamin E; Vitamins | 2012 |
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke | 2003 |
[Age-associated changes in the metabolism of vitamin B(12) and folic acid: prevalence, aetiopathogenesis and pathophysiological consequences].
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Nutritional Status; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
[Role of folates in the nutrition of the elderly].
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cognition Disorders; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Food, Fortified; Health Education; Humans; Hyperhomocysteinemia; Male; Neoplasms; Nutrition Policy; Nutritional Status; Poland; Primary Prevention; Risk Factors | 2004 |
Folate and DNA methylation during in utero development and aging.
Topics: Aging; DNA Methylation; Female; Fetal Development; Folic Acid; Folic Acid Deficiency; Humans; Pregnancy | 2004 |
Health implications of homocysteine and folates: possible preventive measures.
Topics: Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Preventive Medicine; Risk Factors; Sex Characteristics | 2005 |
Interactions between folate and aging for carcinogenesis.
Topics: Aging; Animals; Carbon; DNA Methylation; Folic Acid; Humans; Neoplasms | 2005 |
Genetic and epigenetic interactions between folate and aging in carcinogenesis.
Topics: Aging; Animals; DNA Methylation; Epigenesis, Genetic; Folic Acid; Neoplasms; Rats | 2005 |
Aging and antioxidants. Fruits and vegetables are powerful armor.
Topics: Aging; Antioxidants; Ascorbic Acid; Brassicaceae; Carotenoids; Coenzymes; Drug Synergism; Fatty Acids, Omega-3; Feeding Behavior; Flavonoids; Folic Acid; Fruit; Garlic; Humans; Neuroprotective Agents; Nutrition Policy; Nutritional Requirements; Selenium; Ubiquinone; Vegetables; Vitamin B 12; Vitamin E | 2006 |
Homocysteine lowering with folic acid and vitamin B supplements: effects on cardiovascular disease in older adults.
Topics: Adult; Aging; Animals; Cardiovascular Diseases; Clinical Trials as Topic; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex; Vitamin B Deficiency | 2006 |
B vitamins and berries and age-related neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Blueberry Plants; Cognition; Disease Models, Animal; Folic Acid; Fragaria; Fruit; Humans; Neurodegenerative Diseases; Parkinson Disease; Plant Extracts; Riboflavin; Thiamine; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Epigenetic control of fetal gene expression.
Topics: Aging; Cell Differentiation; Chromatin; Chromatin Assembly and Disassembly; DNA Methylation; Epigenesis, Genetic; Female; Fertilization; Fetal Development; Folic Acid; Gene Expression; Genomic Imprinting; Human Development; Humans; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2008 |
If high folic acid aggravates vitamin B12 deficiency what should be done about it?
Topics: Aging; Anemia; Cognition Disorders; Diagnosis, Differential; Dietary Supplements; Folic Acid; Food, Fortified; Humans; Intestinal Absorption; Nutritional Status; Public Health; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Folate nutrition and older adults: challenges and opportunities.
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Food, Fortified; Homocysteine; Homocystinuria; Humans; Male; Nutritional Status; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Megaloblastic anemias.
Topics: Aging; Anemia, Megaloblastic; Animals; Biological Transport; Folic Acid; Humans; Vitamin B 12 Deficiency | 1994 |
Should all elderly people receive folate supplements?
Topics: Aged; Aging; Coronary Disease; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Nutritional Requirements; Nutritional Status | 1998 |
Nutrition, cancer, and aging.
Topics: Aging; Animals; Antioxidants; Calcium, Dietary; Carcinogens; Dietary Fiber; DNA Damage; Energy Intake; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms; Nutritional Physiological Phenomena; Risk Factors | 1998 |
B vitamins and homocysteine in cardiovascular disease and aging.
Topics: Aging; Cardiovascular Diseases; Diet; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Pyridoxine; Risk Factors; Vitamin B 12; Vitamin B Deficiency | 1998 |
Micronutrients prevent cancer and delay aging.
Topics: Aging; Antioxidants; Diet; Folic Acid; Fruit; Humans; Iron; Neoplasms; Vegetables; Vitamins; Zinc | 1998 |
Vitamin absorption in the elderly.
Topics: Absorption; Aged; Aging; Carotenoids; Folic Acid; Humans; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamins | 1999 |
Can nutrient supplements modify brain function?
Topics: Aging; Animals; Brain; Diet; Dietary Supplements; Fatty Acids, Unsaturated; Folic Acid; Hematinics; Humans; Nutritional Physiological Phenomena; Tryptophan; Tyrosine | 2000 |
The impact of formulation on bioavailability: summary of workshop discussion.
Topics: Aging; Biological Availability; Dietary Supplements; Folic Acid; Humans; Iron | 2001 |
Nutrition and cognitive impairment in the elderly.
Topics: Aged; Aging; Alzheimer Disease; Antioxidants; Avitaminosis; Dementia; Dementia, Vascular; Dietary Supplements; Educational Status; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hypertension; Life Style; Nutritional Physiological Phenomena; Nutritional Status; Risk Factors; Stroke; Vitamin B 12 Deficiency | 2001 |
Quantifying the effect of folic acid.
Topics: Adult; Aged; Aging; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Folic Acid; Hematinics; Humans; Male; Middle Aged; Neural Tube Defects; Pregnancy | 2001 |
Folate, vitamin B12 and vitamin B6 and one carbon metabolism.
Topics: Aged; Aging; Carbon; Folic Acid; Humans; One-Carbon Group Transferases; Vitamin B 12; Vitamin B 6 | 2002 |
Homocysteine, B vitamins, and cognitive deficit in the elderly.
Topics: Aging; Cognition Disorders; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2002 |
Folic acid and homocysteine in age-related disease.
Topics: Aged; Aging; Cardiovascular Diseases; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Mental Disorders; Neoplasms; Neurodegenerative Diseases; Stroke | 2002 |
Folic acid, ageing, depression, and dementia.
Topics: Aged; Aging; Alzheimer Disease; Clinical Trials as Topic; Dementia; Depressive Disorder; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Prospective Studies | 2002 |
Folate status assessment.
Topics: Adolescent; Aged; Aging; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Lactation; Nutrition Assessment; Nutritional Status; Pregnancy; Pregnancy Complications | 1990 |
Iron and folate nutriture during life cycle.
Topics: Aging; Female; Fetus; Folic Acid; Humans; Iron; Male; Nutritional Requirements; Pregnancy | 1988 |
Nutrition and old age: a review.
Topics: Aged; Aging; Animals; Ascorbic Acid; Avitaminosis; Calcium, Dietary; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Folic Acid; Humans; Intestinal Absorption; Milk; Nutritional Physiological Phenomena; Nutritional Requirements; Riboflavin; Thiamine; Vitamin B 12 | 1971 |
Trials
35 trial(s) available for folic acid and Aging
| Article | Year |
|---|---|
Folic acid ingestion improves skeletal muscle blood flow during graded handgrip and plantar flexion exercise in aged humans.
Topics: Age Factors; Aged; Aging; Blood Flow Velocity; Brachial Artery; Female; Femoral Artery; Folic Acid; Hand Strength; Humans; Lower Extremity; Male; Middle Aged; Muscle Contraction; Muscle, Skeletal; Regional Blood Flow; Ultrasonography, Doppler, Duplex; Upper Extremity; Vasodilation; Vasodilator Agents | 2017 |
Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Calcium Carbonate; Cholecalciferol; CpG Islands; Dietary Supplements; DNA Methylation; Double-Blind Method; Epigenesis, Genetic; Female; Folic Acid; Germany; Homocysteine; Humans; Male; Middle Aged; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2018 |
Dietary Intervention Modifies DNA Methylation Age Assessed by the Epigenetic Clock.
Topics: Adult; Aged; Aging; CpG Islands; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Flavonoids; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12 | 2018 |
Effectiveness of the National Program of Complementary Feeding for older adults in Chile on vitamin B12 status in older adults; secondary outcome analysis from the CENEX Study (ISRCTN48153354).
Topics: Aged; Aging; Anemia, Pernicious; Chile; Down-Regulation; Female; Folic Acid; Food Assistance; Food, Fortified; Humans; Intention to Treat Analysis; Lost to Follow-Up; Male; Nutritional Status; Old Age Assistance; Prevalence; Program Evaluation; Sex Characteristics; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
B vitamin supplementation improves cognitive function in the middle aged and elderly with hyperhomocysteinemia.
Topics: Aged; Aged, 80 and over; Aging; China; Cognitive Dysfunction; Dietary Supplements; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Follow-Up Studies; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nursing Homes; Prevalence; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
A Randomized Controlled Trial to Examine the Effect of 2-Year Vitamin B12 and Folic Acid Supplementation on Physical Performance, Strength, and Falling: Additional Findings from the B-PROOF Study.
Topics: Accidental Falls; Aged; Aged, 80 and over; Aging; Dietary Supplements; Female; Folic Acid; Hand Strength; Homocysteine; Humans; Male; Motor Activity; Osteoporotic Fractures; Physical Fitness; Vitamin B 12 | 2016 |
Folic acid supplementation increases cutaneous vasodilator sensitivity to sympathetic nerve activity in older adults.
Topics: Administration, Oral; Aged; Aging; Blood Flow Velocity; Body Temperature; Body Temperature Regulation; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Heat-Shock Response; Humans; Male; Regional Blood Flow; Skin; Skin Physiological Phenomena; Sympathetic Nervous System; Vasodilation | 2017 |
Bread cofortified with folic acid and vitamin B-12 improves the folate and vitamin B-12 status of healthy older people: a randomized controlled trial.
Topics: Aged; Aging; Bread; Double-Blind Method; Erythrocytes; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Concentrations of unmetabolized folic acid and primary folate forms in plasma after folic acid treatment in older adults.
Topics: Aged; Aged, 80 and over; Aging; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2011 |
DNA methylation and cognitive functioning in healthy older adults.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Aging; Cognitive Dysfunction; Cross-Sectional Studies; Cytosine; DNA Methylation; Double-Blind Method; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales | 2012 |
Consumption of gold kiwifruit reduces severity and duration of selected upper respiratory tract infection symptoms and increases plasma vitamin C concentration in healthy older adults.
Topics: Actinidia; Aged; Aging; Antioxidants; Ascorbic Acid; Biomarkers; Cross-Over Studies; Erythrocytes; Female; Folic Acid; Fruit; Humans; Immunity, Innate; Incidence; Lipid Peroxidation; Male; New Zealand; Oxidative Stress; Pigmentation; Pilot Projects; Respiratory Tract Infections; Severity of Illness Index | 2012 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause | 2012 |
Folate catabolite excretion is responsive to changes in dietary folate intake in elderly women.
Topics: 4-Aminobenzoic Acid; Aged; Aged, 80 and over; Aging; Diet; DNA Methylation; Erythrocytes; Female; Folic Acid; Glutamates; Homocysteine; Humans; Kinetics; Middle Aged; Nutritional Status; para-Aminobenzoates | 2003 |
Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2004 |
[6S]5-methyltetrahydrofolate or folic acid supplementation and absorption and initial elimination of folate in young and middle-aged adults.
Topics: Adult; Aging; Area Under Curve; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Intestinal Absorption; Male; Middle Aged; Tetrahydrofolates | 2005 |
Estimation of intake and status of vitamin A, vitamin E and folate in older European adults: the ZENITH.
Topics: Age Factors; Aged; Aging; Chromatography, High Pressure Liquid; Diet Records; Double-Blind Method; Europe; Female; Folic Acid; Humans; Luminescent Measurements; Male; Middle Aged; Nutrition Surveys; Nutritional Status; Prospective Studies; Reference Values; Sex Factors; Vitamin A; Vitamin E | 2005 |
A randomized, double-blind, placebo-controlled trial of nutritional supplementation during acute illness.
Topics: Acute Disease; Aged; Aged, 80 and over; Aging; Diet; Dietary Supplements; Double-Blind Method; Erythrocytes; Female; Folic Acid; Humans; Male; Nutritional Physiological Phenomena; Nutritional Status; Placebos; Vitamin B 12 | 2006 |
Effects of folic acid supplementation on hearing in older adults: a randomized, controlled trial.
Topics: Aged; Aged, 80 and over; Aging; Auditory Threshold; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Hearing Loss, Sensorineural; Homocysteine; Humans; Male; Middle Aged | 2007 |
Associations between underlying disease and nutritional status following acute illness in older people.
Topics: Accidental Falls; Acute Disease; Aged; Aging; Double-Blind Method; Energy Metabolism; Erythrocytes; Female; Folic Acid; Health Status; Heart Failure; Hospitalization; Humans; Length of Stay; Male; Myocardial Ischemia; Nutrition Assessment; Nutritional Requirements; Nutritional Status; Nutritional Support; Pulmonary Disease, Chronic Obstructive; Transferrin | 2007 |
Effect of zinc supplementation on vitamin status of middle-aged and older European adults: the ZENITH study.
Topics: Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Erythrocytes; Female; Folic Acid; Humans; Luminescent Measurements; Male; Mental Recall; Middle Aged; Nutrition Surveys; Nutritional Status; Trace Elements; Vitamin A; Vitamin E; Zinc | 2008 |
Effects of dietary supplements on depressive symptoms in older patients: a randomised double-blind placebo-controlled trial.
Topics: Aged; Aging; Cognition; Depression; Dietary Supplements; Double-Blind Method; Energy Intake; Erythrocytes; Female; Folic Acid; Food, Formulated; Humans; Male; Minerals; Nutrition Policy; Nutritional Status; Nutritive Value; Placebos; Prospective Studies; Time Factors; Treatment Outcome; Vitamin B 12; Vitamins | 2007 |
Decreased plasma folate concentration in young and elderly healthy subjects after a short-term supplementation with isotretinoin.
Topics: Acne Vulgaris; Adult; Aged; Aging; Dermatologic Agents; Dietary Supplements; Folic Acid; Homocysteine; Humans; Isotretinoin; Male; Tetrahydrofolates | 2008 |
Greater intake of vitamins B6 and B12 spares gray matter in healthy elderly: a voxel-based morphometry study.
Topics: Aged; Aging; Body Weights and Measures; Brain; Brain Mapping; Female; Folic Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Regression Analysis; Residence Characteristics; Vitamin B 12; Vitamin B 6 | 2008 |
Unmetabolized folic acid in serum: acute studies in subjects consuming fortified food and supplements.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Animals; Bread; Centers for Disease Control and Prevention, U.S.; Dose-Response Relationship, Drug; Edible Grain; Female; Folic Acid; Food, Fortified; Humans; Incidence; Isotonic Solutions; Male; Middle Aged; Milk; Neural Tube Defects; Sodium Chloride; United States; United States Food and Drug Administration | 1997 |
Definition and prevalence of anemia in Bolivian women of childbearing age living at high altitudes: the effect of iron-folate supplementation.
Topics: Adolescent; Adult; Aging; Altitude; Anemia, Iron-Deficiency; Anthropometry; Bolivia; Female; Folic Acid; Food, Fortified; Hemoglobins; Humans; Iron; Linear Models; Nutritional Status; Prevalence; Public Health | 1997 |
Use of folic acid-fortified milk in the elderly population.
Topics: Aged; Aged, 80 and over; Aging; Animals; Female; Folic Acid; Food, Fortified; Humans; Male; Middle Aged; Milk; Skilled Nursing Facilities; Vitamin B 12 | 1998 |
Age-related hearing loss, vitamin B-12, and folate in elderly women.
Topics: Aged; Aging; Audiometry, Pure-Tone; Diet; Female; Folic Acid; Folic Acid Deficiency; Health Status; Hearing Loss, Functional; Humans; Logistic Models; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Hyperhomocysteinemia in high-aged subjects: relation of B-vitamins, folic acid, renal function and the methylenetetrahydrofolate reductase mutation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Risk Assessment; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 1999 |
The effect of oral nutritional supplements on habitual dietary quality and quantity in frail elders.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Dietary Supplements; Energy Intake; Female; Folic Acid; Frail Elderly; Humans; Male; Nursing Homes; Nutritional Status; Patient Compliance; Placebos | 2000 |
Long-term effects of nitrous oxide anaesthesia on laboratory and clinical parameters in elderly Omani patients: a randomized double-blind study.
Topics: Aged; Aging; Anesthetics, Inhalation; Double-Blind Method; Female; Folic Acid; Hemoglobins; Humans; Male; Middle Aged; Nitrous Oxide; Ophthalmologic Surgical Procedures; Vitamin B 12 | 2000 |
Influence of methylenetetrahydrofolate reductase genotype, age, vitamin B-12, and folate status on plasma homocysteine in children.
Topics: Adolescent; Aging; Chi-Square Distribution; Child; Child, Preschool; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Radioimmunoassay; Vitamin B 12 | 2000 |
Multivitamin/mineral supplementation improves plasma B-vitamin status and homocysteine concentration in healthy older adults consuming a folate-fortified diet.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cerebrovascular Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Minerals; Nutritional Status; Pyridoxal Phosphate; Risk Factors; Vitamin B 12; Vitamin B Complex; Vitamins | 2000 |
Hyperhomocysteinemia and oxidative stress in ischemic stroke.
Topics: Aged; Aged, 80 and over; Aging; Ascorbic Acid; Chromatography, High Pressure Liquid; Female; Folic Acid; Humans; Hyperhomocysteinemia; Lipid Peroxides; Male; Nitric Oxide; Oxidative Stress; Predictive Value of Tests; Stroke; Vitamin B 12 | 2001 |
Five year changes in mental health and associations with vitamin B12/folate status of elderly Europeans.
Topics: Aged; Aged, 80 and over; Aging; Europe; Female; Folic Acid; Humans; Longitudinal Studies; Male; Mental Health; Nutrition Surveys; Psychiatric Status Rating Scales; Time Factors; Vitamin B 12 | 2002 |
Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages.
Topics: Adult; Affect; Aged; Aged, 80 and over; Aging; Diet; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Memory; Middle Aged; Placebos; Vitamin B 12; Vitamin B 6 | 2002 |
Other Studies
294 other study(ies) available for folic acid and Aging
| Article | Year |
|---|---|
Folic acid protects against age-associated apoptosis and telomere attrition of neural stem cells in senescence-accelerated mouse prone 8.
Topics: Aging; Animals; Apoptosis; Folic Acid; In Situ Hybridization, Fluorescence; Male; Mice; Neural Stem Cells; Telomere | 2023 |
Long-term dietary folic acid supplementation attenuated aging-induced hippocampus atrophy and promoted glucose uptake in 25-month-old rats with cognitive decline.
Topics: Aging; Animals; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Glucose; Hippocampus; Male; Rats; Rats, Sprague-Dawley | 2023 |
Traffic-related air pollution and supplemental folic acid intake in relation to DNA methylation in granulosa cells.
Topics: Aging; Air Pollution; DNA Methylation; Female; Folic Acid; Humans; Nitrogen Dioxide | 2023 |
Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer's Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways.
Topics: Aging; Alzheimer Disease; AMP-Activated Protein Kinases; Animals; Folic Acid; Humans; Leucovorin; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Sirtuin 1 | 2023 |
Analysis of spermatogenesis and fertility in adult mice with a hypomorphic mutation in the Mtrr gene.
Topics: Aging; Animals; Ferredoxin-NADP Reductase; Fertility; Folic Acid; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Semen Analysis; Spermatogenesis | 2019 |
Level of vitamin 25 (OH) D and B group vitamins and functional efficiency among the chronically ill elderly in domiciliary care - a pilot study.
Topics: Aged; Aged, 80 and over; Aging; Chronic Disease; Female; Folic Acid; Home Care Services; Humans; Locomotion; Male; Motor Activity; Pilot Projects; Triglycerides; Vitamin B 12; Vitamin D | 2019 |
Vitamin B12 and folate levels in progression of Alzheimer's disease - a short report.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Disease Progression; Female; Folic Acid; Follow-Up Studies; Humans; Male; Retrospective Studies; Vitamin B 12 | 2020 |
Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism.
Topics: Aging; Animals; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Mice; Nerve Degeneration; Telomere Shortening | 2019 |
Relative telomere length and mitochondrial DNA copy number variation with age: Association with plasma folate and vitamin B12.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Cross-Sectional Studies; DNA Copy Number Variations; DNA, Mitochondrial; Female; Folic Acid; Humans; India; Longevity; Male; Middle Aged; Mitochondria; Telomere; Telomere Homeostasis; Vitamin B 12; Young Adult | 2020 |
Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population.
Topics: Aging; Animals; Body Composition; Cytokines; Female; Folic Acid; Horse Diseases; Horses; Inflammation; Male; Nutrients; Pituitary Diseases; Pituitary Gland, Intermediate | 2020 |
Nutrition and aging: is there a link to cognitive health?
Topics: Aged; Aging; Cognition; Cognitive Dysfunction; Diet; Feeding Behavior; Folic Acid; Humans; Nutritional Status | 2020 |
Plasma concentrations of vitamin B
Topics: Aged; Aging; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Humans; Ireland; Longitudinal Studies; Male; Middle Aged; Vitamin B 12 | 2020 |
Increased 25(OH)D3 level in redheaded people: Could redheadedness be an adaptation to temperate climate?
Topics: Adaptation, Physiological; Adult; Aging; Alopecia; Calcifediol; Case-Control Studies; Climate; Evolution, Molecular; Female; Folic Acid; Hair Color; Humans; Male; Middle Aged; Skin Pigmentation; Sunlight; Suntan | 2020 |
Dynamics and interactions of cobalamin and folate status during advanced aging - a longitudinal study in a community-dwelling cohort with multiple follow-ups.
Topics: Aged; Aging; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Independent Living; Longitudinal Studies; Vitamin B 12 | 2020 |
Associations of Plasma Folate and Vitamin B6 With Blood DNA Methylation Age: An Analysis of One-Carbon Metabolites in the VA Normative Aging Study.
Topics: Aged; Aging; Biomarkers; CpG Islands; DNA Methylation; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Regression Analysis; Veterans; Vitamin B 12; Vitamin B 6 | 2021 |
The Stimulation of Neurogenesis Improves the Cognitive Status of Aging Rats Subjected to Gestational and Perinatal Deficiency of B9-12 Vitamins.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Cognitive Dysfunction; Female; Folic Acid; Male; Maze Learning; Neurogenesis; Pregnancy; Rats; Rats, Wistar; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2020 |
Folic acid attenuates remodeling and dysfunction in the aging heart through the ER stress pathway.
Topics: Aging; Animals; Cardiotonic Agents; Cell Line; Endoplasmic Reticulum Stress; Fibrosis; Folic Acid; Heart; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Systole; Ventricular Remodeling | 2021 |
Folic acid prevents habituation memory impairment and oxidative stress in an aging model induced by D-galactose.
Topics: Aging; Animals; Folic Acid; Galactose; Habituation, Psychophysiologic; Hippocampus; Male; Memory; Memory Disorders; Oxidative Stress; Prefrontal Cortex; Rats; Rats, Wistar | 2021 |
Folic Acid Supplementation in the Gestational Phase of Female Rats Improves Age-Related Memory Impairment and Neuroinflammation in Their Adult and Aged Offspring.
Topics: Aging; Animals; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Hippocampus; Inflammation; Memory Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 2021 |
white regulates proliferative homeostasis of intestinal stem cells during ageing in Drosophila.
Topics: Aging; Animals; ATP-Binding Cassette Transporters; Cell Proliferation; Drosophila melanogaster; Drosophila Proteins; Eye Color; Eye Proteins; Folic Acid; Homeostasis; Intestines; Metabolomics; Stem Cells | 2021 |
Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism.
Topics: Aging; Animals; Apoptosis; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Memory; Mice; Morris Water Maze Test; Neurons; Quinazolines; Telomere Shortening; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Uracil | 2021 |
Folic Acid Inhibits Aging-Induced Telomere Attrition and Apoptosis in Astrocytes In Vivo and In Vitro.
Topics: Aging; Animals; Apoptosis; Astrocytes; Folic Acid; Mice; Telomere | 2022 |
Quantitative Proteomic and Metabolomic Profiling Reveals Altered Mitochondrial Metabolism and Folate Biosynthesis Pathways in the Aging Drosophila Eye.
Topics: Aging; Animals; Drosophila melanogaster; Drosophila Proteins; Eye; Eye Proteins; Folic Acid; Male; Metabolome; Metabolomics; Mitochondria; Proteomics | 2021 |
Intake of B vitamins and impairment in physical function in older adults.
Topics: Aged; Aging; Diet; Female; Folic Acid; Health Status; Humans; Male; Middle Aged; Mobility Limitation; Prospective Studies; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2018 |
Vitamin B12 and Homocysteine Associations with Gait Speed in Older Adults: The Baltimore Longitudinal Study of Aging.
Topics: Aged; Aged, 80 and over; Aging; Baltimore; Female; Folic Acid; Gait; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Middle Aged; Vitamin B 12; Walking Speed | 2017 |
Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation.
Topics: Aging; Animals; Cyclins; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Epigenesis, Genetic; Folic Acid; Gene Expression Regulation; Genes, myc; Genes, Tumor Suppressor; JNK Mitogen-Activated Protein Kinases; Liver; Male; Rats, Wistar; S-Adenosylmethionine; Tetrahydrofolates | 2018 |
Elevated Total Homocysteine in All Participants and Plasma Vitamin B12 Concentrations in Women Are Associated With All-Cause and Cardiovascular Mortality in the Very Old: The Newcastle 85+ Study.
Topics: Aged, 80 and over; Aging; Biomarkers; Cardiovascular Diseases; Correlation of Data; Demography; Erythrocytes; Female; Folic Acid; Health Status Disparities; Homocysteine; Humans; Male; Risk Assessment; Risk Factors; Sex Factors; Socioeconomic Factors; United Kingdom; Vitamin B 12 | 2018 |
Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Female; Folic Acid; Glycogen Synthase Kinase 3 beta; Homocysteine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Transgenic; Mutation; Phosphorylation | 2018 |
Voluntary fortification is ineffective to maintain the vitamin B12 and folate status of older Irish adults: evidence from the Irish Longitudinal Study on Ageing (TILDA).
Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cluster Analysis; Cohort Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Geography; Humans; Ireland; Life Style; Longitudinal Studies; Male; Middle Aged; Nutritional Status; Prevalence; Regression Analysis; Risk; Seasons; Smoking; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2018 |
SERUM COBALAMIN AND FOLATE CONCENTRATIONS AS INDICATORS OF GASTROINTESTINAL DISEASE IN KILLER WHALES ( ORCINUS ORCA).
Topics: Aging; Animals; Biomarkers; Female; Folic Acid; Gastrointestinal Diseases; Male; Vitamin B 12; Vitamin B Complex; Whale, Killer | 2018 |
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
Topics: Aging; Amyloid beta-Peptides; Animals; Anxiety; Brain; Cell Survival; Cerebral Cortex; Choline; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Glutamic Acid; Homocystinuria; Liver; Male; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Muscle Spasticity; Nerve Growth Factors; Neurons; Phospholipids; Psychotic Disorders; RNA, Messenger; S-Adenosylmethionine; Synaptic Transmission | 2019 |
Serum Nutrient Levels and Aging Effects on Periodontitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; beta Carotene; Carotenoids; Cryptoxanthins; Energy Intake; Female; Folic Acid; Humans; Male; Middle Aged; Nutrients; Nutrition Surveys; Nutritional Status; Periodontitis; Vitamin D; Vitamin E; Vitamins; Young Adult | 2018 |
Comparison of body condition score and other minimally invasive biomarkers between dogs with gastric carcinoma and dogs with chronic gastritis.
Topics: Aging; Animals; Biomarkers; Blood Cell Count; Body Composition; Carcinoma; Cytokines; Dog Diseases; Dogs; Female; Folic Acid; Gastritis; Male; Stomach Neoplasms; Vitamin B 12 | 2019 |
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study.
Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex | 2019 |
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Topics: Adenylate Kinase; Aging; Animals; Biguanides; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caloric Restriction; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Escherichia coli; Folic Acid; Humans; Hypoglycemic Agents; Longevity; Metagenome; Metformin; Methionine; Transcription Factors | 2013 |
Levodopa, vitamins, ageing and the neuropathy of Parkinson's disease.
Topics: Adult; Aged; Aging; Antiparkinson Agents; Cross-Sectional Studies; Female; Folic Acid; Humans; Levodopa; Male; Middle Aged; Nervous System Diseases; Parkinson Disease; Vitamin B 12 | 2013 |
Longitudinal and secular trends in dietary supplement use: Nurses' Health Study and Health Professionals Follow-Up Study, 1986-2006.
Topics: Adult; Aged; Aging; Antioxidants; Cohort Studies; Diet Surveys; Dietary Supplements; Female; Fish Oils; Folic Acid; Follow-Up Studies; Health Personnel; Humans; Male; Middle Aged; Minerals; Nurses; Prospective Studies; Sex Factors; Smoking; United States; Vitamin D; Vitamins | 2014 |
Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts.
Topics: Aged; Aged, 80 and over; Aging; Australia; Cognition Disorders; Cohort Studies; Female; Folic Acid; Humans; Male; Mental Status Schedule; Vitamin B 12 Deficiency | 2014 |
Maternal micronutrients and brain global methylation patterns in the offspring.
Topics: Aging; Animals; Animals, Newborn; Brain; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Fatty Acids, Omega-3; Female; Folic Acid; Maternal Nutritional Physiological Phenomena; Micronutrients; Neuroprotective Agents; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Vitamin B 12 | 2015 |
Vitamin B(12) and folic acid imbalance modifies NK cytotoxicity, lymphocytes B and lymphoprolipheration in aged rats.
Topics: Aging; Animals; B-Lymphocytes; Cell Proliferation; Concanavalin A; Diet; Dietary Supplements; Folic Acid; Killer Cells, Natural; Leukocyte Common Antigens; Lipopolysaccharides; Liver; Lymphocyte Subsets; Male; Models, Animal; Neutrophils; Phytohemagglutinins; Rats; Rats, Sprague-Dawley; Spleen; Vitamin B 12 | 2013 |
Performance, serum biochemical responses, and gene expression of intestinal folate transporters of young and older laying hens in response to dietary folic acid supplementation and challenge with Escherichia coli lipopolysaccharide.
Topics: Aging; Animals; Chickens; Dietary Supplements; Escherichia coli; Female; Folic Acid; Folic Acid Transporters; Lipopolysaccharides; Oviposition | 2014 |
Has prenatal folate supplementation established an at-risk population for age-related cognitive decline?
Topics: Aging; Cognition Disorders; Dietary Supplements; Female; Folic Acid; Humans; Male; Pregnancy | 2014 |
Methylenetetrahydrofolate reductase 677 genotype-specific reference values for plasma homocysteine and serum folate concentrations in korean population aged 45 to 74 years: the Namwon study.
Topics: Age Factors; Aged; Aging; Cohort Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Reference Values; Republic of Korea; Sex Factors | 2014 |
Folate deficiency-induced oxidative stress contributes to neuropathy in young and aged zebrafish--implication in neural tube defects and Alzheimer's diseases.
Topics: Acetylcysteine; Aging; Alzheimer Disease; Animals; Animals, Genetically Modified; Cathepsin B; Cell Movement; Embryo, Nonmammalian; Folic Acid; Folic Acid Deficiency; gamma-Glutamyl Hydrolase; Green Fluorescent Proteins; Hot Temperature; Microtubule-Associated Proteins; Neural Crest; Neural Tube Defects; Oxidative Stress; Time Factors; Zebrafish; Zebrafish Proteins | 2014 |
Micronutrient intakes among children and adults in Greece: the role of age, sex and socio-economic status.
Topics: Adolescent; Adult; Aged; Aging; Calcium, Dietary; Child; Diet Surveys; Female; Folic Acid; Greece; Humans; Magnesium; Male; Micronutrients; Middle Aged; Nutrition Disorders; Nutritional Requirements; Prevalence; Risk Factors; Sex Factors; Socioeconomic Factors; Vitamin D; Vitamin E | 2014 |
Age dependent levels of plasma homocysteine and cognitive performance.
Topics: Adolescent; Adult; Aged; Aging; Attention; C-Reactive Protein; Cognition; Depression; Female; Folic Acid; Homocysteine; Humans; India; Interleukin-6; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2015 |
Folate and vitamin B12: function and importance in cognitive development.
Topics: Aging; Central Nervous System; Cognition; Cognition Disorders; Dietary Supplements; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Neural Tube Defects; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Altered LINE-1 Methylation in Mothers of Children with Down Syndrome.
Topics: Adult; Aged; Aging; Alcohol Drinking; Body Mass Index; Diet; DNA Methylation; Down Syndrome; Female; Folic Acid; Humans; Long Interspersed Nucleotide Elements; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mothers; Polymorphism, Single Nucleotide; Smoking; Young Adult | 2015 |
Vitamin B12 and folate levels in healthy Swiss senior citizens: a prospective study evaluating reference intervals and decision limits.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Erythrocyte Count; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Reference Values; ROC Curve; Sex Factors; Switzerland; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Divergence between dietary folate intake and concentrations in the serum and red blood cells of aging males in the United States.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Cohort Studies; Diet; Dietary Supplements; Erythrocytes; Folic Acid; Food, Fortified; Humans; Infant; Male; Middle Aged; Nutrition Surveys; United States; Young Adult | 2016 |
The Benefits of Administering Folic Acid in Order to Combat the Oxidative Damage Caused by Binge Drinking in Adolescent Rats.
Topics: Aging; Animals; Binge Drinking; Blood Proteins; DNA Damage; Folic Acid; Glutathione; Lipids; Liver; Male; Oxidation-Reduction; Oxidative Stress; Rats; Vitamin B Complex | 2016 |
Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; DNA-Binding Proteins; Folic Acid; Forkhead Transcription Factors; Glutathione Transferase; Insulin; Insulin-Like Growth Factor I; Longevity; Microscopy, Fluorescence; Models, Animal; Oxidation-Reduction; Oxidative Stress; Real-Time Polymerase Chain Reaction; Signal Transduction; Sirtuins; Superoxide Dismutase; TOR Serine-Threonine Kinases; Transcription Factors | 2015 |
Serum folate, vitamin B-12 and cognitive function in middle and older age: The HAPIEE study.
Topics: Age Factors; Aged; Aging; Biomarkers; Cognition; Cross-Sectional Studies; Europe; Female; Folic Acid; Geriatric Assessment; Humans; Linear Models; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Nutrition Assessment; Nutritional Status; Prospective Studies; Verbal Behavior; Vitamin B 12 | 2016 |
Association between leukocyte telomere length and serum carotenoid in US adults.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Body Mass Index; Carotenoids; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Folic Acid; Homocysteine; Humans; Leukocytes; Logistic Models; Male; Middle Aged; Nutrition Surveys; Socioeconomic Factors; Telomere; Young Adult | 2017 |
Folate Acts in E. coli to Accelerate C. elegans Aging Independently of Bacterial Biosynthesis.
Topics: 4-Aminobenzoic Acid; Aging; Animals; Anti-Bacterial Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Escherichia coli; Folic Acid; Gene Expression Regulation; Glutamate Carboxypeptidase II; Host-Pathogen Interactions; Leucovorin; Longevity; Microbiota; Organic Anion Transporters; Signal Transduction; Sulfamethoxazole; Survival Rate | 2016 |
Gene specific epigenetic regulation of hepatic folate transport system is responsible for perturbed cellular folate status during aging and exogenous modulation.
Topics: Aging; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Liver; Membrane Transport Proteins; Minor Histocompatibility Antigens; Promoter Regions, Genetic; Rats; Reduced Folate Carrier Protein | 2016 |
High folic acid intake reduces natural killer cell cytotoxicity in aged mice.
Topics: Aging; Animals; Cytotoxicity, Immunologic; Female; Folic Acid; Killer Cells, Natural; Mice; Mice, Inbred C57BL | 2016 |
Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney.
Topics: Aging; Animals; Cells, Cultured; Cellular Senescence; Collagen Type XVIII; Endostatins; Endothelial Cells; Extracellular Matrix Proteins; Fibrosis; Folic Acid; GTP-Binding Proteins; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Glutamine gamma Glutamyltransferase 2; Transglutaminases; Up-Regulation | 2016 |
Color by Numbers: When Population Skin Pigmentation Is not Political but a Polytypical Evaluation Exercise to Measure Vitamin D, Diseases, and Skin Pigmentation.
Topics: Aging; Culture; Diet; Folic Acid; Health Status Disparities; Humans; Nutritional Status; Racial Groups; Racism; Skin Pigmentation; Sunlight; Vitamin D; Vitamin D Deficiency | 2016 |
Moderate 'multivitamin' supplementation improved folate and vitamin B12 status in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Dietary Supplements; Female; Folic Acid; Homes for the Aged; Humans; Israel; Male; Middle Aged; Nursing Homes; Retrospective Studies; Vitamin B 12; Vitamins | 2016 |
Vitamin C, vitamin B12, folate and the risk of osteoporotic fractures. A case-control study.
Topics: Aged; Aging; Ascorbic Acid; Case-Control Studies; Causality; Chromatography, High Pressure Liquid; Diet; Diet Records; Female; Folic Acid; Fractures, Bone; Geriatric Assessment; Humans; Immunoassay; Male; Multivariate Analysis; Odds Ratio; Osteoporosis; Risk Factors; Spain; Surveys and Questionnaires; Vitamin B 12 | 2007 |
Conclusions of a WHO Technical Consultation on folate and vitamin B12 deficiencies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Diet; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nutrition Assessment; Nutritional Requirements; Outcome and Process Assessment, Health Care; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; World Health Organization | 2008 |
Serum homocysteine: relationship with circulating levels of cortisol and ascorbate.
Topics: Aging; Ascorbic Acid; Cardiovascular Diseases; Female; Folic Acid; Health Status; Homocysteine; Humans; Hydrocortisone; Linear Models; Male; Middle Aged; Nutritional Status; Risk Factors | 2008 |
Higher folate intake is related to lower risk of Alzheimer's disease in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Assessment; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats.
Topics: Age Factors; Aging; Animals; Biotin; Body Weight; Eating; Folic Acid; Liver; Male; Models, Animal; Niacinamide; Pyridoxal Phosphate; Rats; Tryptophan; Vitamin B 12; Vitamin B Complex | 2008 |
Do dietary patterns in older men influence change in homocysteine through folate fortification? The Normative Aging Study.
Topics: Aged; Aging; Alcohol Drinking; Boston; Cluster Analysis; Diet; Dietary Supplements; Folic Acid; Food, Fortified; Fruit; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Vegetables; Vitamin B Complex | 2009 |
Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Anemia, Pernicious; Cognition Disorders; Drug Interactions; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Middle Aged; Nutrition Surveys; Nutritional Status; Odds Ratio; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition.
Topics: Adipose Tissue; Aging; Animals; Diet; Dietary Fats; Epigenesis, Genetic; Fatty Acids, Nonesterified; Female; Folic Acid; Gene Expression Profiling; Gene Expression Regulation; Lipase; Liver; Male; Muscle, Skeletal; Phenotype; Pregnancy; Prenatal Nutritional Physiological Phenomena; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Sexual Maturation | 2009 |
High-dose short-term folate administration modifies ambulatory blood pressure in postmenopausal women. A placebo-controlled study.
Topics: Aging; Blood Pressure; Cardiovascular Diseases; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin; Middle Aged; Postmenopause; Vitamin B Complex | 2009 |
The associations between blood levels of homocysteine, folate, vitamin B12, and retinal vascular caliber.
Topics: Aged; Aging; Arterioles; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Photography; Retinal Artery; Retinal Vein; Sex Factors; Smoking; Venules; Vitamin B 12 | 2009 |
Folic acid, vitamin B12, and homocysteine levels during fasting and after methionine load in patients with Type 1 diabetes mellitus.
Topics: Adolescent; Adult; Aging; Blood Glucose; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Sex Characteristics; Vitamin B 12; Young Adult | 2010 |
Dietary folate, vitamin B-12, vitamin B-6 and incident Alzheimer's disease: the cache county memory, health and aging study.
Topics: Aged; Aging; Alzheimer Disease; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Humans; Incidence; Longitudinal Studies; Male; Memory; Proportional Hazards Models; Prospective Studies; Surveys and Questionnaires; Utah; Vitamin B 12; Vitamin B 6 | 2009 |
Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aging; Autoimmune Diseases; CD27 Ligand; CD28 Antigens; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Modification Methylases; Female; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Male; Methionine; Micronutrients; Middle Aged; Receptors, KIR; T-Lymphocytes | 2010 |
Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors.
Topics: Aged; Aging; Anemia; Anemia, Macrocytic; Blood Cell Count; Cognition; Cognition Disorders; Cystatin C; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Multivariate Analysis; Nutrition Surveys; Tetrahydrofolates; United States; Vitamin B 12 Deficiency | 2010 |
Vitamin B12 deficiency in African American and white octogenarians and centenarians in Georgia.
Topics: Age Factors; Aged, 80 and over; Aging; Black or African American; Erythrocytes; Female; Folic Acid; Georgia; Homocysteine; Humans; Male; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2010 |
Serum homocysteine and folate concentrations are associated with prevalent age-related hearing loss.
Topics: Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Folic Acid; Health Surveys; Hearing Loss; Homocysteine; Humans; Male; Multivariate Analysis; Odds Ratio; Vitamin B 12 | 2010 |
Polymorphism of MTHFR C677T, serum vitamin levels and cognition in subjects with hyperhomocysteinemia in China.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study.
Topics: Aged; Aging; Alzheimer Disease; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Dementia; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Mental Status Schedule; Odds Ratio; Risk Factors; Transcobalamins | 2010 |
Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age.
Topics: Acetylcholine; Aging; Animals; Brain; Choline; Choline Deficiency; Diet; Dopamine; Folic Acid; Folic Acid Deficiency; Kidney; Liver; Lung; Male; Myocardium; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Vitamin B Complex | 2010 |
Effect of antioxidant vitamins on the plasma homocysteine level in a free-living elderly population.
Topics: Aged; Aging; Antioxidants; Ascorbic Acid; beta Carotene; Cardiovascular Diseases; Cross-Sectional Studies; Female; Folic Acid; Germany; Glomerular Filtration Rate; Homocysteine; Humans; Longitudinal Studies; Male; Vitamin E; Vitamins | 2010 |
Beneficial effects of folic acid on enhancement of memory and antioxidant status in aged rat brain.
Topics: Aging; Animals; Antioxidants; Avoidance Learning; Brain; Cognition Disorders; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Health Status Indicators; Memory; Oxidative Stress; Rats; Rats, Sprague-Dawley; Up-Regulation | 2011 |
Use of calcium, folate, and vitamin D₃-fortified milk for 6 months improves nutritional status but not bone mass or turnover, in a group of Australian aged care residents.
Topics: Aged; Aging; Animals; Australia; Biomarkers; Bone and Bones; Calcium, Dietary; Cholecalciferol; Day Care, Medical; Female; Folic Acid; Food, Fortified; Humans; Male; Milk; Nutritional Requirements; Nutritional Status | 2009 |
Natural food folate and late-life depression.
Topics: Aged; Aging; Case-Control Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Humans; Male; Middle Aged; Nutritional Status; Vitamin B Complex | 2009 |
Challenges and new opportunities for clinical nutrition interventions in the aged.
Topics: Aged; Aged, 80 and over; Aging; Animals; Biomedical Research; Caloric Restriction; Folic Acid; Health Status; Humans; Nutrition Therapy; Nutritional Status; Obesity; Sarcopenia; Socioeconomic Factors; Vitamin B 12 Deficiency | 2011 |
Polyneuropathy and dementia in old age: common inflammatory and vascular parameters.
Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Cohort Studies; Dementia; Female; Folic Acid; Geriatrics; Homocysteine; Humans; Inflammation; Male; Mental Status Schedule; Neopterin; Neural Conduction; Polyneuropathies; Sural Nerve; Vascular Diseases; Vitamin B 12 | 2011 |
Do the effects of APOE-ε4 on cognitive function and decline depend upon vitamin status? MacArthur Studies of Successful Aging.
Topics: Aged; Aging; Apolipoprotein E4; Cognition; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Longitudinal Studies; Male; Nutrigenomics; Nutritional Status; United States; Vitamin B Complex | 2011 |
Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged, 80 and over; Aging; Female; Folic Acid; Genotype; Hearing Loss; Homozygote; Humans; Japan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors | 2011 |
Serum folate is significantly correlated with plasma cysteine concentrations in healthy industry workers.
Topics: Adult; Aged; Aging; Cardiovascular Diseases; Cysteine; Extraction and Processing Industry; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Norway; Risk Factors; Triglycerides; Young Adult | 2011 |
Nutrient intake and anemia risk in the women's health initiative observational study.
Topics: Aged; Aging; Anemia, Iron-Deficiency; Body Mass Index; Cohort Studies; Diet; Female; Folic Acid; Hemoglobins; Humans; Incidence; Iron, Dietary; Logistic Models; Middle Aged; Nutritional Requirements; Odds Ratio; Postmenopause; Prevalence; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12 | 2011 |
Plasma homocysteine and cognitive decline in older hypertensive subjects.
Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cognition Disorders; Executive Function; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hypertension; Male; Neuropsychological Tests; Risk Factors; Vitamin B 12 | 2011 |
Folate/vitamin-B12 prevents chronic hyperhomocysteinemia-induced tau hyperphosphorylation and memory deficits in aged rats.
Topics: Aging; Animals; Chronic Disease; Dietary Supplements; Disease Models, Animal; Drug Therapy, Combination; Folic Acid; Hyperhomocysteinemia; Male; Memory Disorders; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins; Vitamin B 12 | 2011 |
Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Australia; Brain; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Vitamin B 12 | 2011 |
Explaining the variability in recommended intakes of folate, vitamin B12, iron and zinc for adults and elderly people.
Topics: Adolescent; Adult; Age Distribution; Aged; Aging; Biological Availability; Cross-Cultural Comparison; Europe; Female; Folic Acid; Humans; Iron, Dietary; Male; Micronutrients; Middle Aged; Nutrition Policy; Nutritional Physiological Phenomena; Nutritional Requirements; Sex Distribution; Vitamin B 12; Young Adult; Zinc | 2012 |
Associations of polymorphisms of folate cycle enzymes and risk of breast cancer in a Brazilian population are age dependent.
Topics: 5' Untranslated Regions; Adult; Aged; Aging; Brazil; Breast Neoplasms; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genetics, Population; Humans; Middle Aged; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Factors | 2012 |
Relationships among biomarkers of one-carbon metabolism.
Topics: Adult; Aging; Biomarkers; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Vitamin B 12; Young Adult | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Relative validity of the Geisinger Rural Aging Study food frequency questionnaire.
Topics: Aged; Aged, 80 and over; Aging; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Energy Intake; Feeding Behavior; Female; Folic Acid; Follow-Up Studies; Humans; Interviews as Topic; Longitudinal Studies; Male; Micronutrients; Nutrition Assessment; Pennsylvania; Risk Assessment; Rural Population; Surveys and Questionnaires; Zinc | 2012 |
Unmetabolized folic acid prevalence is widespread in the older Irish population despite the lack of a mandatory fortification program.
Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Cross-Sectional Studies; Diet; Erythrocytes; Female; Folic Acid; Food, Fortified; Health Promotion; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutrition Policy; Vitamin B 12; Vitamin B 12 Deficiency; Voluntary Programs | 2012 |
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.
Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Vitamin B 12 | 2012 |
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Conversion from mild cognitive impairment to dementia: influence of folic acid and vitamin B12 use in the VITA cohort.
Topics: Aged; Aging; Atrophy; Austria; Brain; Cognitive Dysfunction; Cohort Studies; Dementia; Dietary Supplements; Disease Progression; Female; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Prospective Studies; Retrospective Studies; Vitamin B 12 | 2012 |
Homocysteine, folate, vitamin B-12, and physical function in older adults: cross-sectional findings from the Singapore Longitudinal Ageing Study.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Gait; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Middle Aged; Mobility Limitation; Postural Balance; Prospective Studies; Singapore; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
A principal component model of medical health: implications for cognitive deficits and decline among adults in a population-based sample.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Blood Glucose; Cholesterol; Cognition; Cognition Disorders; Cross-Sectional Studies; Dementia; Female; Folic Acid; Health Status; Humans; Male; Memory; Memory, Episodic; Mental Recall; Middle Aged; Neuropsychological Tests; Principal Component Analysis; Prospective Studies; Thyrotropin; Thyroxine; Triglycerides | 2013 |
Response of older laying hens to an Escherichia coli lipopolysaccharide challenge when fed diets with or without supplemental folic acid.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cecum; Chickens; Diet; Dietary Supplements; Escherichia coli; Female; Folic Acid; Gene Expression Regulation; Immunoglobulin G; Lipopolysaccharides; Palatine Tonsil; Real-Time Polymerase Chain Reaction; Spleen; T-Lymphocyte Subsets | 2013 |
Elevated serum methylmalonic acid concentrations are common among elderly Americans.
Topics: Adult; Aged; Aging; Black or African American; Creatinine; Female; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2002 |
Homocysteine, cardiovascular disease risk factors, and habitual diet in the French Supplementation with Antioxidant Vitamins and Minerals Study.
Topics: Adult; Aging; Alcohol Drinking; Antioxidants; Apolipoproteins B; Blood Glucose; Body Constitution; Body Mass Index; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Coffee; Dietary Fiber; Dietary Supplements; Energy Intake; Erythrocytes; Exercise; Fasting; Female; Folic Acid; France; Homocysteine; Humans; Male; Middle Aged; Minerals; Risk Factors; Sex Characteristics; Triglycerides; Vitamin B 12; Vitamin B 6; Vitamins | 2002 |
Can homocysteine be related to physical functioning?
Topics: Aged; Aging; Folic Acid; Homocysteine; Humans; Psychomotor Performance; Vitamin B 12; Vitamin B 6 | 2002 |
Will caloric restriction and folate protect against AD and PD?
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Animals; Brain; Brain-Derived Neurotrophic Factor; Caloric Restriction; Disease Models, Animal; Energy Intake; Folic Acid; Homocysteine; Humans; Middle Aged; Neurons; Oxidative Stress; Parkinson Disease; Rats; Risk Factors | 2003 |
Reference values and predictors of white blood cell subset counts: a cross-sectional study among HIV seronegative pregnant women in Zimbabwe.
Topics: Adolescent; Adult; Aging; alpha 1-Antichymotrypsin; beta Carotene; Cross-Sectional Studies; Eosinophils; Female; Ferritins; Folic Acid; Gestational Age; HIV Seronegativity; Humans; Leukocyte Count; Linear Models; Lymphocyte Count; Middle Aged; Monocytes; Neutrophils; Parity; Pregnancy; Reference Values; Seasons; Vitamin A; Zimbabwe | 2003 |
Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey, 1988-1994.
Topics: Adult; Aged; Aging; Alcohol Drinking; Alcoholic Beverages; Beer; Black People; Body Mass Index; Cotinine; Dietary Supplements; Erythrocytes; Female; Folic Acid; Health Status; Hispanic or Latino; Homocysteine; Humans; Life Style; Linear Models; Male; Middle Aged; Nutrition Surveys; Sex Characteristics; Vitamin B 12; Vitamins; White People; Wine | 2003 |
Biochemical and molecular aberrations in the rat colon due to folate depletion are age-specific.
Topics: Aging; Animals; Colon; Colorectal Neoplasms; DNA Methylation; Folic Acid; Folic Acid Deficiency; Male; Rats; Rats, Sprague-Dawley | 2003 |
Folate deficiency is a common finding in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Regression Analysis; Vitamin B 12 | 2002 |
Prevalence and mechanisms of hyperhomocysteinemia in elderly hospitalized patients.
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutritional Status; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Homocysteine: a marker for cognitive performance? A longitudinal follow-up study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cognition Disorders; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Psychomotor Performance; Risk Factors; Vitamin B 12 | 2003 |
Plasma total homocysteine levels, dietary vitamin B6 and folate intake in AD and healthy aging.
Topics: Adult; Aging; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Cholesterol; Educational Status; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Serum Albumin; Smoking; Triglycerides; Vitamin B 6 | 2003 |
Folate and cobalamin levels as determinants of plasma homocysteine in different age groups of healthy controls and psychogeriatric patients.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dementia; Female; Folic Acid; Humans; Hydrolases; Male; Middle Aged; Vitamin B 12 | 2003 |
Ontogenic regulation of folate transport across rat jejunal brush-border membrane.
Topics: Aging; Animals; Animals, Suckling; Biological Transport; Carrier Proteins; Folic Acid; Homeostasis; Intestinal Mucosa; Jejunum; Male; Membrane Proteins; Microvilli; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Distribution; Transcription, Genetic; Weaning | 2003 |
Plasma vitamin B-12 concentrations in an elderly latino population are predicted by serum gastrin concentrations and crystalline vitamin B-12 intake.
Topics: Aged; Aging; Crystallization; Dietary Supplements; Female; Folic Acid; Food; Gastrins; Humans; Male; Middle Aged; Osmolar Concentration; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Effects of dietary folate and aging on gene expression in the colonic mucosa of rats: implications for carcinogenesis.
Topics: Aging; Animals; Colon; Colorectal Neoplasms; Diet; Folic Acid; Gene Expression Regulation; Intestinal Mucosa; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligonucleotide Probes; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53; Urokinase-Type Plasminogen Activator | 2004 |
[Urinary elimination of B complex vitamins in the aged].
Topics: Aging; Body Fluids; Folic Acid; Humans; Vitamin B Complex; Vitamins | 1956 |
[Research on the relation between vitamin coenzymes and corresponding enzymes in relation to the age of the animal and under the influence of certain substances proper to the organism].
Topics: Acetylesterase; Adenine Nucleotides; Aging; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Coenzymes; Cysteine; D-Alanine Transaminase; Folic Acid; Humans; NAD; Niacin; Niacinamide; Pantothenic Acid; Pyridoxine; Riboflavin; Thiamine; Thiamine Pyrophosphate; Vitamins | 1963 |
[Biochemical aspects of the aging process in the central nervous system].
Topics: Aging; Central Nervous System; Corrinoids; Cysteine; Folic Acid; Humans; Proteins; Pyridoxine; Sulfur; Vitamin B 12 | 1962 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. II. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN SULFUR METHYLATION AND METABOLISM ON AMINO ACID METABOLISM IN THE SPINAL CORD OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Spinal Cord; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. III. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN METHYLATION AND METABOLISM OF SULFUR ON AMINO ACID METABOLISM IN THE MESENCEPHALON OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Mesencephalon; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
PRESBYACUSIS: A STUDY.
Topics: Aging; Arteriosclerosis; Diuretics; Ethinyl Estradiol; Folic Acid; Geriatrics; Hearing Disorders; Hearing Loss, Noise-Induced; Humans; Hypertension; Methyltestosterone; Presbycusis; Smoking; Vasodilator Agents; Vitamin B Complex | 1964 |
THE INFLUENCE OF CYSTEINE ON COLLAGEN FIBRES.
Topics: Aging; Body Weight; Collagen; Cysteine; Folic Acid; Metabolism; Pharmacology; Rats; Research | 1963 |
[A THEORY OF AGING].
Topics: Aging; Folic Acid; Humans; Physiology; Vitamin B Deficiency | 1964 |
OXIDIZED GLUTATHIONE AS A TEST OF SENESCENCE.
Topics: Aging; Animals; Biomedical Research; Blood Chemical Analysis; Corrinoids; Cysteine; Folic Acid; Geriatrics; Glutamates; Glutathione; Glutathione Disulfide; Hematinics; Lidocaine; Metabolism; Pyridoxine; Rabbits; Rats; Research; Vitamin B 12 | 1964 |
[LONGITUDINAL EVALUATION IN AGED SUBJECTS, IN THE PICTURE OF RELATIONSHIPS BETWEEN THE SPHEROCYTE TENDENCY OF THE ERYTHROCYTE AND VARIOUS CLINICAL STITUATIONS DUE TO ENZYMATIC-VITAMIN DEFICIENCY].
Topics: Aging; Anemia; Anemia, Hypochromic; Anemia, Macrocytic; Avitaminosis; Biomedical Research; Calcium; Enzymes; Erythrocytes; Erythrocytes, Abnormal; Folic Acid; Geriatrics; Spherocytes; Vitamin B 12; Vitamin B Complex; Vitamin D; Vitamins | 1964 |
[STUDY OF THE NUCLEIC ACIDS IN THE BRAIN, CEREBELLUM AND LIVER AS A FUNCTION OF THE AGE OF THE ANIMAL AND UNDER THE INFLUENCE OF TREATMENT WITH VITAMIN B 12, VITAMIN B 6 AND FOLIC ACID].
Topics: Aging; Animals; Brain; Cerebellum; DNA; Folic Acid; Liver; Metabolism; Pharmacology; Pyridoxine; Rats; Research; RNA; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 1964 |
IDENTIFICATION OF PHOSPHATIDYLINOSITOL AS A FACTOR REQUIRED IN MITOCHONDRIAL CONTRACTION.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aging; Animals; Calcium; Cattle; Dinitrophenols; Folic Acid; Liver; Magnesium; Mitochondria; Oleic Acid; Oligomycins; Pharmacology; Phosphates; Phosphatidylinositols; Phospholipids; Phosphorus Isotopes; Rats; Research; Serum Albumin; Serum Albumin, Bovine; Spectrophotometry; Thyroxine; Vitamin B Complex | 1964 |
[STUDY OF VITAMIN B 12, FOLIC ACID AND PANTOTHENIC ACID IN RABBITS AS A FUNCTION OF AGE AND IN THOSE WITH EXPERIMENTAL ATHEROSCLEROSIS AS WELL AS IN AGED RABBITS TREATED WITH CYSTEINE-FOLIC ACID].
Topics: Aging; Arteriosclerosis; Atherosclerosis; Cysteine; Folic Acid; Humans; Metabolism; Pantothenic Acid; Rabbits; Research; Vitamin B 12; Vitamin B Complex | 1965 |
[Biochemistry of biological aging processes. 3. The blood glutathione level in animals of different ages and the effect of administration of cystein, vitamin B6, vitamin B12 and folic acid on the glutathione level of the aged animal].
Topics: Aging; Animals; Corrinoids; Cysteine; Folic Acid; Glutathione; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 1962 |
Early embryonic death of glutamate carboxypeptidase II (NAALADase) homozygous mutants.
Topics: Aging; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; Blotting, Western; Brain; Brain Chemistry; Dipeptides; Embryo, Mammalian; Exons; Folic Acid; Glutamate Carboxypeptidase II; Hematinics; Homozygote; Intestines; Kidney; Mice; Mice, Knockout; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Hyperhomocystinemia in children with inflammatory bowel disease.
Topics: Adolescent; Aging; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Tetrahydrofolates; Thromboembolism; Vitamin B 12; von Willebrand Factor | 2003 |
Functional vitamin B12 deficiency and determination of holotranscobalamin in populations at risk.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Diet, Vegetarian; Female; Folic Acid; Germany; Homocysteine; Humans; Kidney Diseases; Male; Methylmalonic Acid; Middle Aged; Risk; Syria; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Folate and vitamin E deficiency impair cognitive performance in mice subjected to oxidative stress: differential impact on normal mice and mice lacking apolipoprotein E.
Topics: Aging; Animals; Apolipoproteins E; Cognition Disorders; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Maze Learning; Mice; Mice, Knockout; Neurodegenerative Diseases; Oxidative Stress; Vitamin E; Vitamin E Deficiency | 2003 |
Differences in the metabolic response to exogenous homocysteine in juvenile and adult rabbits.
Topics: Aging; Animals; Disease Models, Animal; Fatty Acids; Folic Acid; Glutathione; Homocysteine; Lipid Peroxidation; Liver; Metabolic Clearance Rate; Rabbits; Thiobarbituric Acid Reactive Substances | 2004 |
Ocular changes, risk markers for eye disorders and effects of cataract surgery in elderly people: a study of an urban Swedish population followed from 70 to 97 years of age.
Topics: Aged; Aged, 80 and over; Aging; Body Mass Index; Cataract Extraction; Eye Diseases; Female; Folic Acid; Follow-Up Studies; Geriatric Assessment; Humans; Male; Prevalence; Risk Factors; Smoking; Sweden; Time Factors; Visual Acuity | 2004 |
[Biochemical parameters of blood and nutrition model of the elderly].
Topics: Aged; Aged, 80 and over; Aging; Albumins; Anemia; Biomarkers; Blood Glucose; Cardiovascular Diseases; Cholesterol, HDL; Diabetes Mellitus; Diet; Female; Folic Acid; Hematocrit; Hemoglobins; Humans; Male; Risk Factors; Vitamin B 12 | 2003 |
Folic acid supplementation for 4 weeks affects liver morphology in aged rats.
Topics: Aging; Animals; Animals, Newborn; Cell Count; Dietary Supplements; Drug Administration Schedule; Folic Acid; Hepatocytes; Keratins; Liver; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Weaning | 2004 |
Effects of paradoxical sleep deprivation on blood parameters associated with cardiovascular risk in aged rats.
Topics: Age Factors; Aging; Animals; Blood Viscosity; Cardiovascular Diseases; Cholesterol; Folic Acid; Homocysteine; Lipoproteins; Male; Rats; Rats, Wistar; Risk Factors; Sleep Deprivation; Triglycerides; Vitamin B 12 | 2004 |
Hyperhomocysteinemia in healthy young men and elderly men with normal serum folate concentration is not associated with poor vascular reactivity or oxidative stress.
Topics: Adult; Aged; Aging; Antioxidants; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Male; Oxidative Stress; Vasodilation | 2004 |
Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Female; Folic Acid; Germany; Homocysteine; Humans; Life Style; Linear Models; Longitudinal Studies; Male; Methionine; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Sex Characteristics; Smoking; Tea; Vitamin B 12 | 2004 |
Increasing production of homocysteine and neopterin and degradation of tryptophan with older age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dioxygenases; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Macrophages; Male; Middle Aged; Neopterin; T-Lymphocytes; Time Factors; Tryptophan; Vitamin B 12 | 2004 |
Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife.
Topics: Adult; Aging; Analysis of Variance; Cognition; Female; Folic Acid; Humans; Male; Mental Recall; Middle Aged; Nutrition Policy; Nutrition Surveys; Nutritional Requirements; Self Disclosure; South Australia; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2004 |
Use of fasting urinary methylmalonic acid to screen for metabolic vitamin B12 deficiency in older persons.
Topics: Aging; Biomarkers; Creatinine; Diet, Vegetarian; Fasting; Female; Folic Acid; Hong Kong; Humans; Kidney Function Tests; Mass Screening; Methylmalonic Acid; Middle Aged; Predictive Value of Tests; ROC Curve; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification.
Topics: Acculturation; Aged; Aging; California; Cross-Sectional Studies; Depression; Diet; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Sex Factors; Vitamin B 12 | 2004 |
Vitamin B-12, serum folate, and cognitive change between 11 and 79 years.
Topics: Adolescent; Adult; Aged; Aging; Child; Cognition; Cognition Disorders; Female; Folic Acid; Humans; Longitudinal Studies; Male; Mental Status Schedule; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Antioxidant intake is associated with semen quality in healthy men.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Ascorbic Acid; beta Carotene; Dietary Supplements; Folic Acid; Humans; Infertility, Male; Male; Middle Aged; Nutrition Assessment; Semen; Sperm Motility; Vitamin E; Zinc | 2005 |
Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
Topics: Aged; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Longitudinal Studies; Male; Risk Factors; Vitamin B 12; Vitamin B 6 | 2005 |
Folate supplementation increases genomic DNA methylation in the liver of elder rats.
Topics: Aging; Animals; Dietary Supplements; DNA Methylation; Folic Acid; Folic Acid Deficiency; Liver; Male; Models, Animal; Rats; Rats, Sprague-Dawley | 2005 |
Adiponectin levels and cardiovascular risk factors in Japanese men with type 2 diabetes.
Topics: Adiponectin; Adult; Aging; Body Mass Index; Cardiovascular Diseases; Cholesterol, HDL; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Folic Acid; gamma-Glutamyltransferase; Glycated Hemoglobin; Homocysteine; Humans; Intercellular Signaling Peptides and Proteins; Japan; Leukocyte Count; Lipids; Male; Middle Aged; Risk Factors; Smoking | 2005 |
Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction.
Topics: Adult; Aged; Aging; Body Mass Index; Case-Control Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Obesity; Pakistan; Pyridoxal Phosphate; Smoking; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2005 |
Total homocysteine and its predictors in Dutch children.
Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Netherlands; Predictive Value of Tests; Vitamin B 12 | 2005 |
Methylation of the ESR1 CpG island in the colorectal mucosa is an 'all or nothing' process in healthy human colon, and is accelerated by dietary folate supplementation in the mouse.
Topics: Aging; Animals; Dietary Supplements; Dinucleoside Phosphates; DNA Methylation; Estrogen Receptor alpha; Folic Acid; Gene Silencing; Humans; Intestinal Mucosa; Mice | 2005 |
Dietary folate improves age-related decreases in lymphocyte function.
Topics: Aging; Animals; Body Weight; Cell Proliferation; Cytokines; Dietary Supplements; Eating; Folic Acid; Ionomycin; Lymph Nodes; Male; Rats; Rats, Inbred F344; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Vitamin B 12 | 2006 |
Population references for plasma total homocysteine concentrations for U.S. children and adolescents in the post-folic acid fortification era.
Topics: Adolescent; Aging; Black People; Child; Child, Preschool; Female; Folic Acid; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Male; Mexican Americans; Osmolar Concentration; Reference Values; Sex Factors; White People | 2005 |
Hyperhomocysteinemia and cognitive function: more than just a casual link?
Topics: Aging; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2005 |
Homocysteine and folate as risk factors for dementia and Alzheimer disease.
Topics: Aged; Aging; Alzheimer Disease; Cognition; Cohort Studies; Cross-Sectional Studies; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Italy; Male; Prospective Studies; Risk Factors; Seroepidemiologic Studies | 2005 |
High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Diet; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2005 |
Folate, mitochondria, ROS, and the aging brain.
Topics: Aged; Aging; Alzheimer Disease; Animals; Brain; Cognition Disorders; DNA, Mitochondrial; Folic Acid; Folic Acid Deficiency; Humans; Mitochondria; Rats; Reactive Oxygen Species; Sequence Deletion | 2005 |
Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cross-Sectional Studies; Dementia; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Neuropsychological Tests; Prospective Studies; Risk Factors; Vitamin B 12 | 2005 |
Age as a determinant of nutritional status: a cross sectional study.
Topics: Aged; Aging; Analysis of Variance; Anthropometry; Ascorbic Acid; Body Mass Index; Body Weight; Calcifediol; Cross-Sectional Studies; Erythrocytes; Folic Acid; Health Status; Hemoglobins; Humans; Nutrition Assessment; Nutritional Status; Regression Analysis; Riboflavin; Serum Albumin; Vitamin B 12 | 2005 |
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12 | 2005 |
Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino Study on Aging.
Topics: Aged; Aged, 80 and over; Aging; California; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Dementia; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Regression Analysis; Vitamin B Complex | 2005 |
[Morphology of neutrophils in centarians].
Topics: Adult; Aged, 80 and over; Aging; Analysis of Variance; Cytoplasm; Female; Folic Acid; Humans; Male; Neutrophils; Poland; Reference Values; Vitamin B 12 | 2005 |
Total serum homocysteine, folate and vitamin B12 in a Greek school age population.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Age Factors; Aging; Blood Pressure; Cardiovascular Diseases; Child; Child Nutritional Physiological Phenomena; Female; Folic Acid; Greece; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Reference Values; Risk Factors; Sex Factors; Social Class; Vitamin B 12; Vitamin B Complex | 2006 |
Dietary folate and vitamins B-12 and B-6 not associated with incident Alzheimer's disease.
Topics: Aged; Aging; Alzheimer Disease; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Humans; Incidence; Male; Prospective Studies; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2006 |
Iron deficiency, but not anemia, upregulates iron absorption in breast-fed peruvian infants.
Topics: Absorption; Aging; Anemia, Iron-Deficiency; Breast Feeding; Ferritins; Folic Acid; Hemoglobins; Homeostasis; Humans; Infant; Iron; Iron Deficiencies; Iron Isotopes; Milk, Human; Peru; Vitamin B 12 | 2006 |
Nutritional status is altered in the self-neglecting elderly.
Topics: Aged; Aged, 80 and over; Aging; Bone and Bones; C-Reactive Protein; Calcifediol; Elder Abuse; Erythrocytes; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Iron; Male; Nutritional Status; Osteocalcin; Self Care; Sex Characteristics; Vitamin D; Vitamins | 2006 |
Reference range of total serum homocysteine level and dietary indexes in healthy Greek schoolchildren aged 6-15 years.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Aging; Anthropometry; Blood Pressure; Body Mass Index; Child; Child Nutritional Physiological Phenomena; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Sex Characteristics; Vitamin B 12 | 2006 |
Total homocysteine, folate, and cobalamin, and their relation to genetic polymorphisms, lifestyle and body mass index in healthy children and adolescents.
Topics: Adolescent; Aging; Blood Pressure; Body Mass Index; Child; Child, Preschool; Cholesterol; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Sex Characteristics; Triglycerides; Vitamin B 12 | 2006 |
Population reference values for plasma total homocysteine concentrations in US adults after the fortification of cereals with folic acid.
Topics: Adult; Age Distribution; Aged; Aging; Edible Grain; Female; Folic Acid; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Male; Mexican Americans; Middle Aged; Nutrition Surveys; Reference Values; Sex Distribution; White People | 2006 |
Methylmalonic acid and cognitive function in the Medical Research Council Cognitive Function and Ageing Study.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Geriatrics; Humans; Language Tests; Longitudinal Studies; Male; Methylmalonic Acid; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Homocysteine, folate, and vitamin B-12 and cognitive performance in older Chinese adults: findings from the Singapore Longitudinal Ageing Study.
Topics: Aged; Aged, 80 and over; Aging; China; Cognition; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Middle Aged; Psychological Tests; Singapore; Vitamin B 12; Vitamin B Complex | 2006 |
Biomarkers of folate and vitamin B12 are related in blood and cerebrospinal fluid.
Topics: Adult; Aged; Aging; Biomarkers; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 | 2007 |
Summaries for patients. The effect of folic acid on hearing in older adults.
Topics: Aged; Aged, 80 and over; Aging; Auditory Threshold; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Hearing Loss, Sensorineural; Homocysteine; Humans; Male; Middle Aged | 2007 |
Folate supplementation and age-related hearing loss.
Topics: Aged; Aging; Dietary Supplements; Folic Acid; Hearing Loss, Sensorineural; Humans | 2007 |
Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification.
Topics: Aged; Aging; Anemia; Anemia, Macrocytic; Cognition Disorders; Confidence Intervals; Creatinine; Female; Folic Acid; Food, Fortified; Humans; Male; Nutrition Surveys; Nutritional Status; Odds Ratio; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Low folate and the risk of cognitive and functional deficits in the very old: the Monzino 80-plus study.
Topics: Activities of Daily Living; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Geriatric Assessment; Humans; Linear Models; Male; Nutritional Requirements; Vitamin B 12; Vitamin B Complex | 2006 |
Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging.
Topics: Aged; Aged, 80 and over; Aging; California; Cognition Disorders; Dementia; Disease Susceptibility; Female; Folic Acid; Health Surveys; Hispanic or Latino; Homocysteine; Humans; Incidence; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12 | 2007 |
Associations between folate, vitamin B12, homocysteine and pathologies related to aging: the need to consider complex nutrient-nutrient and gene-nutrient interactions and the functional and socio-economic determinants in population-based studies.
Topics: Aging; Epidemiology; Folic Acid; Food; Genes; Homocysteine; Humans; Socioeconomic Factors; Vitamin B 12 | 2007 |
Association of vitamin B12, folate and homocysteine with functional and pathological characteristics of the elderly in a mountainous village in Sicily.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Diabetes Mellitus; Folic Acid; Homocysteine; Humans; Middle Aged; Neoplasms; Peripheral Vascular Diseases; Sicily; Stroke; Vitamin B 12 | 2007 |
Association of thyroid dysfunction with vitamin B12, folate and plasma homocysteine levels in the elderly: a population-based study in Sicily.
Topics: Aged; Aged, 80 and over; Aging; Epidemiology; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Sicily; Thyroid Diseases; Vitamin B 12 | 2007 |
Homocysteine increases the risk of mortality in elderly individuals.
Topics: Aged; Aging; Biomarkers; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Mortality; Selenium; Spain; Survival Analysis; Vitamin B 12 | 2007 |
Folate and ageing.
Topics: Aged; Aging; Cognition; Depression; Folic Acid; Folic Acid Deficiency; Hematinics; Humans; Schizophrenia | 2007 |
Older age and dietary folate are determinants of genomic and p16-specific DNA methylation in mouse colon.
Topics: Aging; Animals; Colon; Diet; Dietary Supplements; DNA Methylation; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Genes, p16; Genome; Male; Mice; Mice, Inbred C57BL; Time Factors | 2007 |
Elevated plasma homocysteine concentration in elderly patients with mental illness is mainly related to the presence of vascular disease and not the diagnosis.
Topics: Aged; Aged, 80 and over; Aging; Creatinine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Kidney Function Tests; Male; Mental Disorders; Psychiatric Status Rating Scales; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
B-vitamins and homocysteine in Spanish institutionalized elderly.
Topics: Aged; Aged, 80 and over; Aging; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Institutionalization; Male; Middle Aged; Regression Analysis; Sex Characteristics; Spain; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2007 |
Changes in mitochondrial DNA deletion, content, and biogenesis in folate-deficient tissues of young rats depend on mitochondrial folate and oxidative DNA injuries.
Topics: Aging; Animals; DNA Damage; DNA, Mitochondrial; Folic Acid; Gene Deletion; Homocysteine; Mitochondria; Oxidation-Reduction; Rats; Rats, Wistar; RNA, Messenger | 2007 |
Plasma folate concentration and cognitive performance: Rotterdam Scan Study.
Topics: Aged; Aged, 80 and over; Aging; Brain; Cognition; Confidence Intervals; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Memory; Middle Aged; Multivariate Analysis; Netherlands; Odds Ratio; Prospective Studies; Psychomotor Performance | 2007 |
Concurrent folate treatment prevents Na+,K+-ATPase activity inhibition and memory impairments caused by chronic hyperhomocysteinemia during rat development.
Topics: Aging; Animals; Chronic Disease; Cognition; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Motor Activity; Nerve Tissue Proteins; Parietal Lobe; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Space Perception; Synaptic Membranes; Thiobarbituric Acid Reactive Substances; Vitamins | 2007 |
Growth-related changes of parameters of the methylation cycle and jejunal aminopeptidase M in the rat.
Topics: Aging; Animals; CD13 Antigens; Female; Folic Acid; Growth; Homocysteine; Jejunum; Methylation; Rats; Rats, Inbred Lew; Vitamin B 12 | 2008 |
Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Apolipoprotein E4; China; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors; Sex Factors | 2009 |
Postweaning dietary folate deficiency provided through childhood to puberty permanently increases genomic DNA methylation in adult rat liver.
Topics: Aging; Animals; Diet; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Profiling; Gene Expression Regulation; Liver; Rats; Rats, Sprague-Dawley; Sexual Maturation; Weaning | 2008 |
Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Acetylcholine; Aggression; Aging; Animals; Apolipoproteins E; Cognition; Folic Acid; Folic Acid Deficiency; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Random Allocation; S-Adenosylmethionine | 2008 |
Effect of biotin, pantothenic acid and nicotinic acid deficiencies on amino acid transport in Lactobacillus plantarum.
Topics: Acetates; Aging; Avitaminosis; Biological Transport; Biotin; Carbon Isotopes; Cell Membrane Permeability; Chloramphenicol; Folic Acid; Glutamates; Lactobacillus; Nicotinic Acids; Pantothenic Acid; Potassium Chloride; Sucrose | 1967 |
Folic acid metabolism in pregnancy.
Topics: Adult; Aging; Anemia, Macrocytic; Bone Marrow Examination; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Infant, Newborn; Infant, Newborn, Diseases; Parity; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic | 1967 |
Demographic analysis of serum folate and folate-binding capacity in hospitalized patients.
Topics: Adult; Aging; Black People; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Male; Middle Aged; Outpatients; Patients; Receptors, Cell Surface; Retrospective Studies; Sex Factors; White People | 1983 |
Effect of age on poly- and monoglutamyl folacin absorption in human subjects.
Topics: Adult; Aged; Aging; Biopsy; Chromatography; Folic Acid; gamma-Glutamyl Hydrolase; Humans; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Perfusion; Pteroylpolyglutamic Acids | 1984 |
Relationship between nutrition and dementia in the elderly.
Topics: Acetylcholine; Aged; Aged, 80 and over; Aging; Aluminum; Choline; Cognition; Dementia; Folic Acid; Humans; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; Psychoses, Alcoholic; Thiamine Deficiency; Vitamin B 12 | 1983 |
The effect of age of breeder hen on the levels of vitamins and minerals in turkey eggs.
Topics: Aging; Animals; Biotin; Calcium; Eggs; Female; Folic Acid; Housing, Animal; Minerals; Pantothenic Acid; Pyridoxine; Selenium; Turkeys; Vitamin B 12; Vitamins | 1983 |
Uptake and metabolism of [3H] pteroylglutamic acid by developing chick embryo.
Topics: Aging; Animals; Chick Embryo; Folic Acid; Pteroylpolyglutamic Acids; Time Factors | 1983 |
Anemias in the elderly: physiologic or pathologic?
Topics: Aged; Aging; Alcoholism; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Pernicious; Animals; Blood Cell Count; Drug-Related Side Effects and Adverse Reactions; Female; Ferrous Compounds; Folic Acid; Folic Acid Deficiency; Gastrointestinal Hemorrhage; Humans; Male; Mice; Reference Values; Vitamin B 12 | 1982 |
Developmental changes in the folate-dependent enzymes of de novo purine biosynthesis in rat brain.
Topics: Acyltransferases; Aging; Animals; Brain; Folic Acid; Hydroxymethyl and Formyl Transferases; Kidney; Kinetics; Liver; Male; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Purines; Rats; Rats, Inbred Strains; Spleen; Tissue Distribution | 1982 |
Composition of milk from red and grey kangaroos with particular reference to vitamins.
Topics: Aging; Animals; Dietary Fats; Fatty Acids; Female; Folic Acid; Lactation; Macropodidae; Milk; Milk Proteins; Pregnancy; Riboflavin; Vitamins | 1982 |
Transport of 5-methyltetrahydrofolic acid in erythrocytes from various mammalian species.
Topics: Aging; Animals; Biological Transport; Dogs; Erythrocytes; Folic Acid; Guinea Pigs; Humans; Kinetics; Rabbits; Rats; Sheep; Species Specificity; Swine; Tetrahydrofolates | 1981 |
The blood-brain barrier and folate deficiency.
Topics: Adult; Aged; Aging; Blood-Brain Barrier; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Middle Aged | 1981 |
Plasma and red cell folacin in cow's milk-fed infants and children during the first 2 years of life: the significance of boiling pasteurized cow's milk.
Topics: Adult; Aging; Animals; Cattle; Child, Preschool; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Food Handling; Hemoglobins; Humans; Infant; Infant Food; Infant Nutritional Physiological Phenomena; Male; Middle Aged; Milk; Nutritive Value; Sterilization | 1980 |
The effect of aging on the blood count.
Topics: Adult; Aged; Aging; Anemia; Blood Cell Count; Blood Sedimentation; Erythrocyte Indices; Female; Folic Acid; Hematologic Tests; Hematopoiesis; Hemoglobins; Humans; Iron; Leukocyte Count; Male; Middle Aged; Vitamin B 12 | 1980 |
Radioimmunoassay of folic acid and its correlation with age.
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Humans; Male; Middle Aged; Radioimmunoassay; Sex Characteristics | 1994 |
Extensive laboratory assessment of nutritional status in fit, health-conscious, elderly people living in the Paris area. Research Group on Aging.
Topics: Aged; Aged, 80 and over; Aging; Amino Acids; Anthropometry; Calcifediol; Calcitriol; Calcium; Female; Ferritins; Folic Acid; France; Humans; Magnesium; Male; Nutrition Assessment; Nutritional Status; Phosphorus; Physical Fitness; Prealbumin; Serum Albumin; Social Class; Transferrin; Vitamin B 12 | 1994 |
Aging. Increased responsiveness of colorectal mucosa to carcinogen stimulation and protective role of folic acid.
Topics: Aging; Analysis of Variance; Animals; Colon; Folic Acid; Intestinal Mucosa; Male; Methylazoxymethanol Acetate; Organ Culture Techniques; Ornithine Decarboxylase; Pilot Projects; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Rectum; Specific Pathogen-Free Organisms | 1995 |
Effects of ageing on folate metabolism in rats fed a long-term folate deficient diet.
Topics: Aging; Animals; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population.
Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex | 1993 |
Effects of folic acid and folinic acid on cognitive and motor behaviors in 20-month-old rats.
Topics: Aging; Animals; Body Weight; Cognition; Folic Acid; Learning; Leucovorin; Male; Memory; Motor Activity; Psychomotor Performance; Rats; Rats, Inbred F344; Space Perception | 1993 |
Age- and gender-specific reference intervals for total homocysteine and methylmalonic acid in plasma before and after vitamin supplementation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Reference Values; Sex Characteristics; Vitamin B 12; Vitamins | 1996 |
Functional and psychic deterioration in elderly people may be aggravated by folate deficiency.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Anthropometry; Body Height; Body Weight; Eating; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Intelligence Tests; Iron; Male; Prospective Studies; Social Class; Spain; Surveys and Questionnaires; Vitamin B 12 | 1996 |
Alteration of plasma folates in gestating sows and newborn piglets.
Topics: Aging; Animals; Animals, Newborn; Female; Folic Acid; Injections, Intravenous; Lactation; Pregnancy; Pregnancy, Animal; Swine; Tetrahydrofolates | 1996 |
Vitamin intake and vitamin status in Germany.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Ascorbic Acid; Carotenoids; Female; Folic Acid; Humans; Male; Middle Aged; Nutritional Status; Smoking; Vitamin B 12; Vitamin E; Vitamins | 1995 |
Folate and vitamin B12 status of the elderly.
Topics: Aged; Aging; Female; Folic Acid; Humans; Male; Nutritional Requirements; Nutritional Status; Reference Values; Risk Factors; Vitamin B 12 | 1996 |
Changes in the vitamin status of elderly Europeans: plasma vitamins A, E, B-6, B-12, folic acid and carotenoids. SENECA Investigators.
Topics: Aged; Aging; Carotenoids; Europe; Female; Folic Acid; Health Surveys; Humans; Longitudinal Studies; Male; Nutritional Status; Pyridoxine; Random Allocation; Vitamin A; Vitamin B 12; Vitamin E; Vitamins | 1996 |
Effects of serum vitamin B12 and folate status on episodic memory performance in very old age: a population-based study.
Topics: Age Factors; Aged; Aging; Brain; Female; Folic Acid; Humans; Male; Memory Disorders; Mental Recall; Vitamin B 12 | 1996 |
Are different reference intervals for methylmalonic acid and total homocysteine necessary in elderly people?
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Reference Values; Vitamin B 12 | 1996 |
Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations.
Topics: Aged; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Odds Ratio; Osmolar Concentration; Peritoneal Dialysis, Continuous Ambulatory; Pyridoxine; Renal Dialysis; Risk Factors; Sex Distribution; Vitamin B 12 | 1996 |
Use of methotrexate in older patients. A risk-benefit assessment.
Topics: Aged; Aging; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Folic Acid; Humans; Methotrexate; Risk Assessment | 1996 |
Nutritional status and cognitive functioning in a normally aging sample: a 6-y reassessment.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Female; Folic Acid; Food, Fortified; Humans; Male; Niacin; Nutrition Assessment; Nutritional Status; Pyridoxine; Riboflavin; Thiamine; Time Factors; Vitamin A; Vitamin B 12; Vitamin E | 1997 |
Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis.
Topics: Adult; Aging; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxal Phosphate; Risk Factors; Sex Characteristics; Vitamin B 12; Vitamin B Complex | 1997 |
Are dietary factors involved in DNA methylation associated with colon cancer?
Topics: Aged; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Colonic Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Pyridoxine; Retrospective Studies; Risk Factors; Vitamin B 12 | 1997 |
Major lifestyle determinants of plasma total homocysteine distribution: the Hordaland Homocysteine Study.
Topics: Adult; Aged; Aging; Coffee; Cohort Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Life Style; Male; Reference Values; Sex Factors; Smoking; Surveys and Questionnaires | 1998 |
[Decreased erythropoiesis and biochemical deviations in psychogeriatric patients].
Topics: Aged; Aged, 80 and over; Aging; Erythrocytes; Erythropoiesis; Female; Folic Acid; Humans; Male; Mental Disorders; Reticulocytes; Serum Albumin; Transketolase; Vitamin B 12 | 1998 |
Plasma total-homocysteine in anorexia nervosa.
Topics: Adolescent; Aging; Anorexia Nervosa; Child; Chromatography, High Pressure Liquid; Creatinine; Female; Folic Acid; Homocysteine; Humans; Reference Values; Vitamin B 12 | 1998 |
Variability and determinants of total homocysteine concentrations in plasma in an elderly population.
Topics: Aged; Aging; Blood Pressure; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Male; Regression Analysis; Reproducibility of Results; Seasons; Sex Factors; Vitamin B 12 | 1998 |
Folate, vitamin D, and iron intakes are low among pregnant Finnish women.
Topics: Adult; Aging; Animals; Diet Surveys; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; Dietary Supplements; Educational Status; Energy Intake; Female; Finland; Folic Acid; Humans; Iron, Dietary; Nutritional Physiological Phenomena; Pregnancy; Pregnancy Trimester, Third; Vitamin D | 1998 |
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors; Vascular Diseases; Vitamin B 12 | 1998 |
Thiamine deficiency is prevalent in a selected group of urban Indonesian elderly people.
Topics: Aged; Aging; Body Mass Index; Diet; Energy Intake; Erythrocytes; Female; Folic Acid; Health Status; Hemoglobins; Humans; Indonesia; Male; Middle Aged; Surveys and Questionnaires; Thiamine Deficiency; Transketolase; Urban Population; Vitamin A; Vitamin B 12 | 1999 |
Plasma total homocysteine and cysteine in relation to glomerular filtration rate in diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Aging; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Insulin; Middle Aged; Vitamin B 12 | 1999 |
Folate and folate-dependent enzymes associated with rat CNS development.
Topics: Aging; Animals; Brain; Caudate Nucleus; Cerebellum; Cerebral Cortex; Folic Acid; Formate-Tetrahydrofolate Ligase; Immunohistochemistry; Oxidoreductases Acting on CH-NH Group Donors; Putamen; Rats; Rats, Sprague-Dawley | 1999 |
[Changes in serum levels of folic acid after total gastrectomy].
Topics: Aged; Aged, 80 and over; Aging; Carcinoma; Case-Control Studies; Female; Folic Acid; Gastrectomy; Humans; Male; Middle Aged; Stomach Neoplasms; Time Factors | 1997 |
Serum levels of folic acid and vitamin B12 in Korean patients with vitiligo.
Topics: Adolescent; Adult; Aging; Child; Female; Folic Acid; Humans; Male; Middle Aged; Sex Characteristics; Vitamin B 12; Vitiligo | 1999 |
Serum folate and homocysteine concentrations in large population samples of US ethnic and racial groups.
Topics: Adolescent; Aging; Child; Female; Folic Acid; Homocysteine; Humans; Male; Mexican Americans; Racial Groups; United States; White People | 1999 |
Serum vitamin B12, C and folate concentrations in the New Mexico elder health survey: correlations with cognitive and affective functions.
Topics: Affect; Aged; Aging; Ascorbic Acid; Cognition; Female; Folic Acid; Hispanic or Latino; Humans; Male; New Mexico; Vitamin B 12; Vitamins | 2000 |
Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun study.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Atrophy; Catholicism; Female; Folic Acid; Humans; Longitudinal Studies; Neocortex; Registries; United States | 2000 |
Vitamin intake of 1- to 18-year-old German children and adolescents in the light of various recommendations.
Topics: Adolescent; Aging; Ascorbic Acid; Carotenoids; Child; Child, Preschool; Folic Acid; Germany; Humans; Infant; Niacin; Nutrition Policy; Vitamin A; Vitamin B Complex; Vitamin E; Vitamins | 2000 |
Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey.
Topics: Adolescent; Adult; Aged; Aging; Contraceptives, Oral, Hormonal; Creatinine; Estrogens; Female; Folic Acid; Health Surveys; Homocysteine; Hormone Replacement Therapy; Humans; Male; Middle Aged; United States; Vitamin B 12 | 2000 |
Age-related hearing impairment and B vitamin status.
Topics: Acoustic Impedance Tests; Age Factors; Aged; Aged, 80 and over; Aging; Audiometry, Pure-Tone; Audiometry, Speech; Female; Folic Acid; Homocysteine; Humans; Male; Presbycusis; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Folate intake, lifestyle factors, and homocysteine concentrations in younger and older women.
Topics: Adult; Aged; Aging; Blood Pressure; Body Mass Index; Coffee; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Life Style; Linear Models; Middle Aged; Reference Values; Smoking | 2000 |
Blood homocysteine and vitamin B levels are not associated with cognitive skills in healthy normally ageing subjects.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cognition; Dementia; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12 | 2000 |
Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore.
Topics: Aged; Aging; Asian People; Cohort Studies; Exercise; Female; Folic Acid; Genotype; Homocysteine; Humans; Interviews as Topic; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Pyridoxine; Risk Factors; Sex Factors; Singapore; Smoking; Vascular Diseases; Vitamin B 12 | 2001 |
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dementia; Dementia, Vascular; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Pyridoxine; Reference Values; Vitamin B 12 | 2000 |
Lifestyle effects on homocysteine and an alcohol paradox.
Topics: Aged; Aging; Alcohol Drinking; Animals; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male | 2001 |
Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Cross-Sectional Studies; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Life Style; Linear Models; Male; Methylmalonic Acid; Risk Factors; Smoking; Tea; Vascular Diseases; Vitamin B 12 | 2001 |
The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study.
Topics: Aged; Aging; Alleles; Demography; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Regression Analysis; Sex Characteristics; Vitamin B 12 | 2001 |
Ontogeny of hepatic enzymes involved in serine- and folate-dependent one-carbon metabolism in rabbits.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Brain; Carrier Proteins; Embryonic and Fetal Development; Female; Folic Acid; Glycine Hydroxymethyltransferase; Kidney; Leucovorin; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Oxidoreductases Acting on CH-NH Group Donors; Placenta; Pregnancy; Rabbits; Serine; Tetrahydrofolates; Transferases | 2001 |
Genetic aspects of nutrition and toxicology: report of a workshop.
Topics: Aging; Animals; Diet; Dietary Fats, Unsaturated; Disease Models, Animal; Folic Acid; Gene Expression Regulation; Humans; Neoplasms; Nutritional Physiological Phenomena; Toxicology; Zinc | 2001 |
The influence of serum vitamin B12 and folate status on cognitive functioning in very old age.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Long-term nutrient intake and early age-related nuclear lens opacities.
Topics: Aged; Aging; Antioxidants; Ascorbic Acid; beta Carotene; Cataract; Cohort Studies; Diet Records; Diet Surveys; Feeding Behavior; Female; Folic Acid; Humans; Lens Nucleus, Crystalline; Lutein; Middle Aged; Odds Ratio; Prevalence; Riboflavin; Vitamin E; Women's Health; Xanthophylls; Zeaxanthins | 2001 |
Hyperhomocysteinemia in advanced age.
Topics: Aged; Aging; Chronic Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Time Factors; Vitamin B 6 | 2001 |
High dietary folate supplementation: effects on diet utilization and methionine metabolism in aged rats.
Topics: Aging; Analysis of Variance; Animals; Biomarkers; Dietary Fats; Dietary Proteins; Dietary Supplements; DNA Methylation; Folic Acid; Male; Methionine; Rats; Rats, Wistar | 2002 |
Homocysteine levels in elderly Spanish people: influence of pyridoxine, vitamin B12 and folic acid intakes.
Topics: Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Diet Records; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Male; Prospective Studies; Pyridoxine; Spain; Vitamin B 12 | 2002 |
Short-term folic acid supplementation induces variable and paradoxical changes in plasma homocyst(e)ine concentrations.
Topics: Aged; Aging; Cystathionine beta-Synthase; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Sex Characteristics; Smoking; Vitamins | 2001 |
Micro- and macrovascular complications and hyperhomocysteinaemia in type 1 diabetic patients.
Topics: Adult; Aging; Blood Pressure; Cholesterol; Cholesterol, HDL; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Time Factors | 2001 |
Correlates of plasma homocysteine, cysteine and cysteinyl-glycine in respondents in the British National Diet and Nutrition Survey of young people aged 4-18 years, and a comparison with the survey of people aged 65 years and over.
Topics: Adolescent; Aged; Aging; Biomarkers; Child; Child, Preschool; Cysteine; Diet Surveys; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Seasons; Sex Factors; Smoking; United Kingdom; Vitamin B 12; Vitamin B 6 | 2002 |
Homocysteine, B vitamin status, and cognitive function in the elderly.
Topics: Aged; Aging; Cognition; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Intelligence; Male; Psychological Tests; Vitamin B 12 | 2002 |
Effect of low levels of serum vitamin B12 and folic acid on cognitive performance in old age: a population-based study.
Topics: Aged; Aging; Cognition Disorders; Female; Folic Acid; Humans; Male; Memory Disorders; Middle Aged; Netherlands; Neuropsychological Tests; Vitamin B 12 | 2001 |
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
Topics: Age Factors; Aging; Animals; Aspartic Acid; Folic Acid; Folic Acid Deficiency; Isoaspartic Acid; Liver; Male; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2002 |
Erythrocyte folate levels in young and old.
Topics: Adult; Aged; Aging; Erythrocytes; Female; Folic Acid; Geriatrics; Hospital Units; Humans; Long-Term Care; Male; Reference Values | 1979 |
Sparing effect of folic acid deficiency on the development of vitamin B12 deficiency in baboons fed a vitamin B12 deficient diet.
Topics: Aging; Animals; Blood Cells; Body Weight; Folic Acid; Folic Acid Deficiency; Haplorhini; Liver; Male; Papio; Vitamin B 12; Vitamin B 12 Deficiency | 1977 |
Folate metabolism in the superior cervical ganglion histochemical study.
Topics: Aging; Animals; Cattle; Folic Acid; Ganglia, Sympathetic; Histocytochemistry; NADH Dehydrogenase; Tetrahydrofolate Dehydrogenase | 1979 |
Histochemical study on the dihydrofolatereductase and folic acid in mammalian brain cortex.
Topics: Aging; Animals; Cattle; Cerebral Cortex; Folic Acid; NADH Dehydrogenase; Tetrahydrofolate Dehydrogenase | 1979 |
"In situ" variation of folic acid and dihydrofolate reductase in the caudate nucleus in the ageing process.
Topics: Aging; Animals; Cattle; Caudate Nucleus; Folic Acid; NADH Dehydrogenase; Neurons; Tetrahydrofolate Dehydrogenase | 1979 |
A conspectus of research on folacin requirements of man.
Topics: Adolescent; Adult; Aged; Aging; Animals; Child; Child, Preschool; Coenzymes; Female; Fetus; FIGLU Test; Folic Acid; Folic Acid Deficiency; Food Analysis; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Lactation; Male; Middle Aged; Nutrition Surveys; Nutritional Requirements; Pregnancy; Pteroylpolyglutamic Acids | 1978 |
Geriatric mental function and serum folate: a review and survey.
Topics: Aged; Aging; Fasting; Feeding Behavior; Folic Acid; Folic Acid Deficiency; Humans; Mental Disorders; Mental Processes; Nutritional Physiological Phenomena | 1977 |
Neurochemical and behavioral effects of diet related perinatal folic acid restriction.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Brain; Diet; Escape Reaction; Female; Folic Acid; Folic Acid Deficiency; Liver; Mice; Organ Size; Pregnancy; S-Adenosylmethionine; Stress, Physiological | 1976 |
Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status.
Topics: Adult; Aged; Aging; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Pyridoxal Phosphate; Sex Characteristics; Vascular Diseases; Vitamin B 12 | 1992 |
Aging, chronic administration of ethanol, and acute exposure to nitrous oxide: effects on vitamin B12 and folate status in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Alcoholism; Animals; Disease Models, Animal; Folic Acid; Male; Nitrous Oxide; Rats; Rats, Inbred F344; Vitamin B 12 | 1992 |
Factors influencing mutation at the hprt locus in T-lymphocytes: studies in normal women and women with benign and malignant breast masses.
Topics: Adult; Aged; Aging; Breast Neoplasms; Chromosome Aberrations; Clone Cells; Cloning, Molecular; Female; Folic Acid; Humans; Hypoxanthine Phosphoribosyltransferase; Longitudinal Studies; Male; Middle Aged; Mutation; Nutritional Physiological Phenomena; Prospective Studies; Reference Values; Sister Chromatid Exchange; Smoking; T-Lymphocytes | 1992 |
Chromosomal fragile site expression in dogs: I. Breed specific differences.
Topics: Aging; Animals; Aphidicolin; Breeding; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Culture Media; Diterpenes; Dogs; Female; Folic Acid; Genetic Variation; Lymphocytes; Male; Risk; Sex Factors; X Chromosome | 1991 |
Chromosomal fragile site expression in dogs: II. Expression in boxer dogs with mast cell tumors.
Topics: Aging; Animals; Chromosome Fragile Sites; Chromosome Fragility; Cytogenetics; Disease Susceptibility; Dog Diseases; Dogs; Female; Folic Acid; Genetic Variation; Lymphocytes; Male; Mast-Cell Sarcoma; Risk; Tumor Cells, Cultured; X Chromosome | 1991 |
A community study of vitamin B12 and folate levels in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Humans; Male; New Zealand; Prospective Studies; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 1991 |
Effect of nitrous oxide on folate and vitamin B12 metabolism in patients.
Topics: Adult; Aged; Aging; Female; Folic Acid; Formiminoglutamic Acid; Humans; Male; Middle Aged; Nitrous Oxide; Postoperative Period; Preanesthetic Medication; Random Allocation; Vitamin B 12 | 1990 |
Disruption of folate and vitamin B12 metabolism in aged rats following exposure to nitrous oxide.
Topics: Aging; Animals; Brain; Folic Acid; Kidney; Liver; Male; Nitrous Oxide; Rats; Rats, Inbred F344; Vitamin B 12 | 1990 |
The role of folate and vitamin B-12 in neurotransmitter metabolism and degenerative neurological changes associated with aging: proceedings of a workshop.
Topics: Aging; Folic Acid; Humans; Neurotransmitter Agents; Nutritional Status; Vitamin B 12 | 1989 |
Aging: effect on hepatic metabolism and transport of folate in the rat.
Topics: Aging; Animals; Biological Transport; Body Weight; Chromatography, High Pressure Liquid; Coenzymes; Folic Acid; Liver; Rats; Rats, Inbred F344 | 1989 |
Serum folates in young dairy heifers.
Topics: Aging; Animals; Body Weight; Cattle; Female; Folic Acid; Hematocrit; Hemoglobins; Light; Random Allocation; Time Factors | 1989 |
Whole blood folate values in normal female hamsters (Mesocricetus auratus).
Topics: Aging; Animals; Cricetinae; Female; Folic Acid; Mesocricetus; Reference Values | 1988 |
Folate and vitamin B12 levels in an urban elderly population with chronic diseases. Assessment of two laboratory folate assays: microbiologic and radioassay.
Topics: Adult; Aged; Aging; Chronic Disease; Female; Folic Acid; Humans; Male; Middle Aged; Radioimmunoassay; Urban Population; Vitamin B 12 | 1986 |
Folic acid responsive postmenopausal homocysteinemia.
Topics: Adult; Aging; Cystine; Dipeptides; Fasting; Female; Folic Acid; Glycine; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Serine | 1985 |
Amphotericin B- and folic acid-induced nephropathies in developing rats.
Topics: Aging; Amphotericin B; Animals; Animals, Newborn; Body Weight; Creatinine; Female; Folic Acid; Injections, Subcutaneous; Kidney; Kidney Diseases; Kidney Function Tests; Male; Organ Size; Rats; Uremia | 1985 |
Problems of interpretation of laboratory findings in the old.
Topics: Aged; Aging; Anemia, Hypochromic; Blood Glucose; Blood Sedimentation; Calcium; Cholesterol; Clinical Laboratory Techniques; Creatinine; Diabetes Mellitus; Female; Folic Acid; Geriatrics; Hemoglobinometry; Humans; Iodine; Iron; Leukocyte Count; Male; Osteomalacia; Phosphoric Monoester Hydrolases; Protein Binding; Thyroid Diseases; Urea; Uric Acid; Vitamin B 12 | 1973 |
Intestinal transport of tritiated folic acid (3H-PGA) in the everted gut asc of different aged rats.
Topics: Aging; Animals; Folic Acid; Folic Acid Deficiency; Glucose; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Male; Rats; Statistics as Topic; Time Factors; Tritium | 1974 |
[Vitamins. 17. The vitamin requirements of aged].
Topics: Aged; Aging; Ascorbic Acid; Avitaminosis; Cooking; Diet; Diet Fads; Folic Acid; Humans; Intestinal Absorption; Nutritional Physiological Phenomena; Nutritional Requirements; Pyridoxine; Sweden; Vitamins | 1972 |
Errors and artefacts in serum folic-acid assays. Effects of age, food, drugs and radiation.
Topics: Aging; Anti-Bacterial Agents; Biological Assay; Blood Chemical Analysis; Busulfan; Chloroquine; Diet; Folic Acid; Folic Acid Deficiency; Humans; Lactobacillus; Radiation Effects; Sulfaguanidine; Sulfonamides | 1965 |