flutamide has been researched along with Anxiety in 7 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Depression-like behaviors were assessed with the Forced Swim Test (FST) and the Sucrose Preference Test (SPT), and anxiety-like behaviors were assessed with the Open Field Test (OFT) and the Novelty-Suppressed Feeding Test (NSFT)." | 7.76 | Effects of neonatal flutamide treatment on hippocampal neurogenesis and synaptogenesis correlate with depression-like behaviors in preadolescent male rats. ( McCarthy, MM; Regenold, WT; Tonelli, L; Zhang, JM, 2010) |
| "Testosterone (T) and its 5alpha-reduced metabolite, dihydrotestosterone (DHT), can decrease anxiety-like behavior; however, the mechanisms underlying these effects have not been established." | 7.73 | Intrahippocampal administration of an androgen receptor antagonist, flutamide, can increase anxiety-like behavior in intact and DHT-replaced male rats. ( Edinger, KL; Frye, CA, 2006) |
| " Depression-like behaviors were assessed with the Forced Swim Test (FST) and the Sucrose Preference Test (SPT), and anxiety-like behaviors were assessed with the Open Field Test (OFT) and the Novelty-Suppressed Feeding Test (NSFT)." | 3.76 | Effects of neonatal flutamide treatment on hippocampal neurogenesis and synaptogenesis correlate with depression-like behaviors in preadolescent male rats. ( McCarthy, MM; Regenold, WT; Tonelli, L; Zhang, JM, 2010) |
| "Testosterone (T) and its 5alpha-reduced metabolite, dihydrotestosterone (DHT), can decrease anxiety-like behavior; however, the mechanisms underlying these effects have not been established." | 3.73 | Intrahippocampal administration of an androgen receptor antagonist, flutamide, can increase anxiety-like behavior in intact and DHT-replaced male rats. ( Edinger, KL; Frye, CA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, JM | 1 |
| Tonelli, L | 1 |
| Regenold, WT | 1 |
| McCarthy, MM | 1 |
| Svensson, AI | 1 |
| Fernández-Guasti, A | 1 |
| MartÃnez-Mota, L | 1 |
| Edinger, KL | 1 |
| Frye, CA | 1 |
| Kouvelas, D | 1 |
| Pourzitaki, C | 1 |
| Papazisis, G | 1 |
| Dagklis, T | 1 |
| Dimou, K | 1 |
| Kraus, MM | 1 |
| Zimmerberg, B | 1 |
| Farley, MJ | 1 |
| Caubet, JF | 1 |
1 trial available for flutamide and Anxiety
| Article | Year |
|---|---|
Re: Quality of life in advanced prostate cancer: results of a randomized therapeutic trial.
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Anxiety; Depression; Flutamide; Humans; Male; | 1999 |
6 other studies available for flutamide and Anxiety
| Article | Year |
|---|---|
Effects of neonatal flutamide treatment on hippocampal neurogenesis and synaptogenesis correlate with depression-like behaviors in preadolescent male rats.
Topics: Androgen Antagonists; Androgens; Animals; Animals, Newborn; Anxiety; Dentate Gyrus; Depression; DNA | 2010 |
Flutamide treatment induces anxiolytic-like behavior in adult castrated rats.
Topics: Androgen Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Dihydrotestosterone; | 2012 |
Anxiolytic-like actions of testosterone in the burying behavior test: role of androgen and GABA-benzodiazepine receptors.
Topics: Androgen Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Dose-Response Relatio | 2005 |
Intrahippocampal administration of an androgen receptor antagonist, flutamide, can increase anxiety-like behavior in intact and DHT-replaced male rats.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Animals; Anxiety; Dihydrotestosterone; Drug Imp | 2006 |
Nandrolone abuse decreases anxiety and impairs memory in rats via central androgenic receptors.
Topics: Anabolic Agents; Androgen Antagonists; Animals; Anxiety; Behavior, Animal; Body Weight; Brain Chemis | 2008 |
Sex differences in anxiety behavior in rats: role of gonadal hormones.
Topics: Animals; Animals, Newborn; Anxiety; Appetitive Behavior; Arousal; Body Weight; Conditioning, Operant | 1993 |