flunitrazepam and Coma
flunitrazepam has been researched along with Coma in 14 studies
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sleepiness, agitation and ataxia were significantly more frequent in the children." | 5.28 | Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children. ( Descotes, J; Frantz, P; Mollon, P; Pham, E; Pulce, C, 1992) |
| "Report on a case of cardiac arrest and coma lasting 10 hours secondary to the i." | 5.26 | [Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)]. ( Janda, A; Wagner, G, 1980) |
| "Coma-induced bullae and sweat gland necrosis is a rare clinicopathological entity often associated with drug-induced coma." | 1.32 | Drug-induced sweat gland necrosis in a non-comatose patient: a case presentation. ( Aste, N; Atzori, L; Biggio, P; Ferreli, C; Pinna, M; Sulica, VI, 2003) |
| "Sleepiness, agitation and ataxia were significantly more frequent in the children." | 1.28 | Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children. ( Descotes, J; Frantz, P; Mollon, P; Pham, E; Pulce, C, 1992) |
| "With increasing depth of coma, the number of detectable VEP components decreased." | 1.28 | [Neuro-monitoring using visual evoked potentials in comatose neurologic intensive care patients]. ( Adler, G; Bransi, A; Prange, HW, 1991) |
| "Hepatic coma was associated with no changes in the affinities of these receptors but with significant increases in their densities: 0." | 1.27 | Gamma-aminobutyric acid and benzodiazepine receptors in an animal model of fulminant hepatic failure. ( Fowler, JM; Jones, EA; Munson, PJ; Schafer, DF; Thakur, AK; Waggoner, JG, 1983) |
| "Report on a case of cardiac arrest and coma lasting 10 hours secondary to the i." | 1.26 | [Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)]. ( Janda, A; Wagner, G, 1980) |
Research
Studies (14)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ferreli, C | 1 |
| Sulica, VI | 1 |
| Aste, N | 1 |
| Atzori, L | 1 |
| Pinna, M | 1 |
| Biggio, P | 1 |
| Janda, A | 1 |
| Wagner, G | 1 |
| Barbi, S | 1 |
| Pala, F | 1 |
| Beccia, F | 1 |
| Arpino, I | 1 |
| Sabato, AF | 1 |
| Jäger, U | 1 |
| Hruby, K | 1 |
| Haubenstock, A | 1 |
| Fasching, I | 1 |
| Schafer, DF | 1 |
| Fowler, JM | 1 |
| Munson, PJ | 1 |
| Thakur, AK | 1 |
| Waggoner, JG | 1 |
| Jones, EA | 1 |
| Schmutzler, S | 1 |
| Uges, D | 1 |
| Agoston, S | 1 |
| Langrehr, D | 1 |
| Briefer, JP | 1 |
| Unger, PF | 1 |
| Pulce, C | 1 |
| Mollon, P | 1 |
| Pham, E | 1 |
| Frantz, P | 1 |
| Descotes, J | 1 |
| Adler, G | 1 |
| Bransi, A | 1 |
| Prange, HW | 1 |
| Ascensión, A | 1 |
| Duarte, J | 1 |
| Gutiérrez, P | 1 |
| Marucs, EL | 1 |
| Lewinsohn, G | 1 |
| Hofer, P | 1 |
| Scollo-Lavizzari, G | 1 |
| Langendijk, PN | 1 |
| van Loenen, AC | 1 |
| van Heijst, AN | 1 |
| Deleu, D | 1 |
| de Keyser, J | 1 |
Other Studies
14 other studies available for flunitrazepam and Coma
| Article | Year |
|---|---|
Drug-induced sweat gland necrosis in a non-comatose patient: a case presentation.
Topics: Adult; Anxiety; Biopsy, Needle; Blister; Bromazepam; Coma; Female; Flunitrazepam; Follow-Up Studies; | 2003 |
[Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)].
Topics: Anti-Anxiety Agents; Bradycardia; Coma; Dose-Response Relationship, Drug; Female; Flunitrazepam; Hea | 1980 |
Concentrations of free amino acids in plasma and brain in experimental coma due to flunitrazepam in guinea pigs.
Topics: Amino Acids; Animals; Anti-Anxiety Agents; Brain Chemistry; Coma; Flunitrazepam; Guinea Pigs | 1982 |
[Comparative clinical toxicology of 5 benzodiazepine derivatives].
Topics: Adult; Anti-Anxiety Agents; Bromazepam; Child; Coma; Diazepam; Dose-Response Relationship, Drug; Fem | 1984 |
Gamma-aminobutyric acid and benzodiazepine receptors in an animal model of fulminant hepatic failure.
Topics: Animals; Coma; Disease Models, Animal; Female; Flunitrazepam; Galactosamine; Hepatic Encephalopathy; | 1983 |
[Rohypnol poisoning as a cause of postanesthetic coma and the success of 4-aminopyridine therapy].
Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Coma; Female; Flunitrazepam; Humans; Naloxone; P | 1984 |
[Emergency medicine for the practitioner: coma and confusional states].
Topics: Adult; Aged; Anti-Anxiety Agents; Cognition Disorders; Coma; Epilepsy, Absence; Family Practice; Fem | 1997 |
Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children.
Topics: Adolescent; Age Factors; Anti-Anxiety Agents; Ataxia; Benzodiazepines; Benzodiazepinones; Child, Pre | 1992 |
[Neuro-monitoring using visual evoked potentials in comatose neurologic intensive care patients].
Topics: Adult; Aged; Coma; Critical Care; Evoked Potentials, Visual; Female; Flunitrazepam; Humans; Intracra | 1991 |
[Flunitrazepam: a cause of coma with brainstem dysfunction simulating structural damage].
Topics: Aged; Aged, 80 and over; Brain Stem; Coma; Diagnosis, Differential; Female; Flunitrazepam; Humans | 1989 |
Bullous skin lesions--a clue to the diagnosis of coma.
Topics: Aged; Coma; Flunitrazepam; Humans; Male; Skin Diseases, Vesiculobullous | 1989 |
Benzodiazepine antagonist Ro 15-1788 in self-poisoning. Diagnostic and therapeutic use.
Topics: Adult; Aged; Anti-Anxiety Agents; Antidotes; Benzodiazepinones; Coma; Diazepam; Electroencephalograp | 1985 |
[Overdoses of flunitrazepam and various other benzodiazepines; experiences of the National Poisoning Information Center].
Topics: Anti-Anxiety Agents; Coma; Critical Care; Flunitrazepam; Humans; Information Services; Netherlands; | 1986 |
Flunitrazepam intoxication simulating a structural brainstem lesion.
Topics: Brain Stem; Coma; Decerebrate State; Flunitrazepam; Humans; Male; Middle Aged; Reflex, Abnormal; Sui | 1987 |