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flunitrazepam and Coma

flunitrazepam has been researched along with Coma in 14 studies

Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.

Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Research Excerpts

ExcerptRelevanceReference
"Sleepiness, agitation and ataxia were significantly more frequent in the children."5.28Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children. ( Descotes, J; Frantz, P; Mollon, P; Pham, E; Pulce, C, 1992)
"Report on a case of cardiac arrest and coma lasting 10 hours secondary to the i."5.26[Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)]. ( Janda, A; Wagner, G, 1980)
"Coma-induced bullae and sweat gland necrosis is a rare clinicopathological entity often associated with drug-induced coma."1.32Drug-induced sweat gland necrosis in a non-comatose patient: a case presentation. ( Aste, N; Atzori, L; Biggio, P; Ferreli, C; Pinna, M; Sulica, VI, 2003)
"Sleepiness, agitation and ataxia were significantly more frequent in the children."1.28Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children. ( Descotes, J; Frantz, P; Mollon, P; Pham, E; Pulce, C, 1992)
"With increasing depth of coma, the number of detectable VEP components decreased."1.28[Neuro-monitoring using visual evoked potentials in comatose neurologic intensive care patients]. ( Adler, G; Bransi, A; Prange, HW, 1991)
"Hepatic coma was associated with no changes in the affinities of these receptors but with significant increases in their densities: 0."1.27Gamma-aminobutyric acid and benzodiazepine receptors in an animal model of fulminant hepatic failure. ( Fowler, JM; Jones, EA; Munson, PJ; Schafer, DF; Thakur, AK; Waggoner, JG, 1983)
"Report on a case of cardiac arrest and coma lasting 10 hours secondary to the i."1.26[Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)]. ( Janda, A; Wagner, G, 1980)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's3 (21.43)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferreli, C1
Sulica, VI1
Aste, N1
Atzori, L1
Pinna, M1
Biggio, P1
Janda, A1
Wagner, G1
Barbi, S1
Pala, F1
Beccia, F1
Arpino, I1
Sabato, AF1
Jäger, U1
Hruby, K1
Haubenstock, A1
Fasching, I1
Schafer, DF1
Fowler, JM1
Munson, PJ1
Thakur, AK1
Waggoner, JG1
Jones, EA1
Schmutzler, S1
Uges, D1
Agoston, S1
Langrehr, D1
Briefer, JP1
Unger, PF1
Pulce, C1
Mollon, P1
Pham, E1
Frantz, P1
Descotes, J1
Adler, G1
Bransi, A1
Prange, HW1
Ascensión, A1
Duarte, J1
Gutiérrez, P1
Marucs, EL1
Lewinsohn, G1
Hofer, P1
Scollo-Lavizzari, G1
Langendijk, PN1
van Loenen, AC1
van Heijst, AN1
Deleu, D1
de Keyser, J1

Other Studies

14 other studies available for flunitrazepam and Coma

ArticleYear
Drug-induced sweat gland necrosis in a non-comatose patient: a case presentation.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2003, Volume: 17, Issue:4

    Topics: Adult; Anxiety; Biopsy, Needle; Blister; Bromazepam; Coma; Female; Flunitrazepam; Follow-Up Studies;

2003
[Intraoperative cardiac arrest and postoperative coma secondary to flunitrazepam (Rohypnol) (author's transl)].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1980, Volume: 15, Issue:5

    Topics: Anti-Anxiety Agents; Bradycardia; Coma; Dose-Response Relationship, Drug; Female; Flunitrazepam; Hea

1980
Concentrations of free amino acids in plasma and brain in experimental coma due to flunitrazepam in guinea pigs.
    Resuscitation, 1982, Volume: 10, Issue:1

    Topics: Amino Acids; Animals; Anti-Anxiety Agents; Brain Chemistry; Coma; Flunitrazepam; Guinea Pigs

1982
[Comparative clinical toxicology of 5 benzodiazepine derivatives].
    Der Nervenarzt, 1984, Volume: 55, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Bromazepam; Child; Coma; Diazepam; Dose-Response Relationship, Drug; Fem

1984
Gamma-aminobutyric acid and benzodiazepine receptors in an animal model of fulminant hepatic failure.
    The Journal of laboratory and clinical medicine, 1983, Volume: 102, Issue:6

    Topics: Animals; Coma; Disease Models, Animal; Female; Flunitrazepam; Galactosamine; Hepatic Encephalopathy;

1983
[Rohypnol poisoning as a cause of postanesthetic coma and the success of 4-aminopyridine therapy].
    Der Anaesthesist, 1984, Volume: 33, Issue:6

    Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Coma; Female; Flunitrazepam; Humans; Naloxone; P

1984
[Emergency medicine for the practitioner: coma and confusional states].
    Revue medicale de la Suisse romande, 1997, Volume: 117, Issue:4

    Topics: Adult; Aged; Anti-Anxiety Agents; Cognition Disorders; Coma; Epilepsy, Absence; Family Practice; Fem

1997
Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children.
    Veterinary and human toxicology, 1992, Volume: 34, Issue:2

    Topics: Adolescent; Age Factors; Anti-Anxiety Agents; Ataxia; Benzodiazepines; Benzodiazepinones; Child, Pre

1992
[Neuro-monitoring using visual evoked potentials in comatose neurologic intensive care patients].
    EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1991, Volume: 22, Issue:4

    Topics: Adult; Aged; Coma; Critical Care; Evoked Potentials, Visual; Female; Flunitrazepam; Humans; Intracra

1991
[Flunitrazepam: a cause of coma with brainstem dysfunction simulating structural damage].
    Revista clinica espanola, 1989, Volume: 185, Issue:7

    Topics: Aged; Aged, 80 and over; Brain Stem; Coma; Diagnosis, Differential; Female; Flunitrazepam; Humans

1989
Bullous skin lesions--a clue to the diagnosis of coma.
    Intensive care medicine, 1989, Volume: 15, Issue:5

    Topics: Aged; Coma; Flunitrazepam; Humans; Male; Skin Diseases, Vesiculobullous

1989
Benzodiazepine antagonist Ro 15-1788 in self-poisoning. Diagnostic and therapeutic use.
    Archives of internal medicine, 1985, Volume: 145, Issue:4

    Topics: Adult; Aged; Anti-Anxiety Agents; Antidotes; Benzodiazepinones; Coma; Diazepam; Electroencephalograp

1985
[Overdoses of flunitrazepam and various other benzodiazepines; experiences of the National Poisoning Information Center].
    Nederlands tijdschrift voor geneeskunde, 1986, Nov-08, Volume: 130, Issue:45

    Topics: Anti-Anxiety Agents; Coma; Critical Care; Flunitrazepam; Humans; Information Services; Netherlands;

1986
Flunitrazepam intoxication simulating a structural brainstem lesion.
    Journal of neurology, neurosurgery, and psychiatry, 1987, Volume: 50, Issue:2

    Topics: Brain Stem; Coma; Decerebrate State; Flunitrazepam; Humans; Male; Middle Aged; Reflex, Abnormal; Sui

1987