fentanyl and Coma
fentanyl has been researched along with Coma in 21 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Time to first coma was associated with fentanyl and midazolam doses (p=0." | 7.79 | Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors. ( Cossette, M; Leger, C; Michaud, V; Skrobik, Y; Turgeon, J, 2013) |
| "Illicit opioids, consisting largely of fentanyl, novel synthetic opioids, and adulterants, are the primary cause of drug overdose fatality in the United States." | 4.31 | Opioid overdoses involving xylazine in emergency department patients: a multicenter study. ( Aldy, K; Amaducci, A; Brent, J; Calello, D; Hendrickson, R; Hughes, A; Judge, B; Krotulski, AJ; Kurt, A; Levine, M; Logan, BK; Love, JS; Manini, AF; Pizon, A; Schwarz, E; Shulman, J; Vargas-Torres, C; Walton, SE; Wax, P; Wiegan, T, 2023) |
| "We compared two sedation regimens (propofol-remifentanil, period P2, vs midazolam-fentanyl, period P1) among comatose TTM-treated CA survivors." | 3.88 | Comparison of two sedation regimens during targeted temperature management after cardiac arrest. ( Ben Hadj Salem, O; Bougouin, W; Cariou, A; Champigneulle, B; Charpentier, J; Chiche, JD; Dumas, F; Geri, G; Guillemet, L; Legriel, S; Mira, JP; Paul, M; Sandroni, C, 2018) |
| "Time to first coma was associated with fentanyl and midazolam doses (p=0." | 3.79 | Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors. ( Cossette, M; Leger, C; Michaud, V; Skrobik, Y; Turgeon, J, 2013) |
| " We report a case of a 19-month-old girl who presented in coma and who was later found to have a fentanyl patch adhered to her back." | 3.77 | Toxic leukoencephalopathy due to transdermal fentanyl overdose. ( Bradin, SA; Foy, L; Seeyave, DM, 2011) |
| "Five cases of post narcotic delirium, somnolence or coma are interpreted as central anticholinergic syndromes as they were reversed by physostigmine." | 3.66 | [Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)]. ( Jost, U; Ruppert, M; Schmid, A, 1982) |
| "The early recognition of psychogenic coma can result in reduced iatrogenic complications, hospital cost, and physician anxiety." | 2.44 | Psychogenic coma following upper endoscopy: a case report and review of the literature. ( Downs, JW; Durning, SJ; Young, PE, 2008) |
Research
Studies (21)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 10 (47.62) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Love, JS | 1 |
| Levine, M | 1 |
| Aldy, K | 1 |
| Brent, J | 1 |
| Krotulski, AJ | 1 |
| Logan, BK | 1 |
| Vargas-Torres, C | 1 |
| Walton, SE | 1 |
| Amaducci, A | 1 |
| Calello, D | 1 |
| Hendrickson, R | 1 |
| Hughes, A | 1 |
| Kurt, A | 1 |
| Judge, B | 1 |
| Pizon, A | 1 |
| Schwarz, E | 1 |
| Shulman, J | 1 |
| Wiegan, T | 1 |
| Wax, P | 1 |
| Manini, AF | 1 |
| Tanios, M | 1 |
| Nguyen, HM | 1 |
| Le, QA | 1 |
| Park, H | 1 |
| Devlin, JW | 1 |
| Müller, S | 1 |
| Nussbaumer, S | 1 |
| Plitzko, G | 1 |
| Ludwig, R | 1 |
| Weinmann, W | 1 |
| Krähenbühl, S | 1 |
| Liakoni, E | 1 |
| Paul, M | 1 |
| Bougouin, W | 1 |
| Dumas, F | 1 |
| Geri, G | 1 |
| Champigneulle, B | 1 |
| Guillemet, L | 1 |
| Ben Hadj Salem, O | 1 |
| Legriel, S | 1 |
| Chiche, JD | 1 |
| Charpentier, J | 1 |
| Mira, JP | 1 |
| Sandroni, C | 2 |
| Cariou, A | 1 |
| Fraser, GL | 1 |
| Worby, CP | 1 |
| Riker, RR | 1 |
| Gusmao-Flores, D | 1 |
| Carvalho, JP | 1 |
| Quarantini, LC | 1 |
| Granata, R | 1 |
| Bossi, P | 1 |
| Bertulli, R | 1 |
| Saita, L | 1 |
| Soar, J | 1 |
| Friberg, H | 1 |
| Downs, JW | 1 |
| Young, PE | 1 |
| Durning, SJ | 1 |
| Bektas, F | 1 |
| Eken, C | 1 |
| Sayrac, V | 1 |
| Chamorro, C | 1 |
| Borrallo, JM | 1 |
| Romera, MA | 1 |
| Foy, L | 1 |
| Seeyave, DM | 1 |
| Bradin, SA | 1 |
| Skrobik, Y | 1 |
| Leger, C | 1 |
| Cossette, M | 1 |
| Michaud, V | 1 |
| Turgeon, J | 1 |
| Behrman, A | 1 |
| Goertemoeller, S | 1 |
| Boulard, G | 1 |
| Maurette, P | 2 |
| Pouguet, P | 1 |
| Dautheriben, M | 1 |
| Viallefont, E | 1 |
| Besse, JL | 1 |
| Dabadie, P | 2 |
| Sabathié, M | 1 |
| Jost, U | 1 |
| Schmid, A | 1 |
| Ruppert, M | 1 |
| Stuerenburg, HJ | 1 |
| Claassen, J | 1 |
| Eggers, C | 1 |
| Hansen, HC | 1 |
| Chang, J | 1 |
| Fish, KJ | 1 |
| Brule, JF | 1 |
| Thicoipe, M | 1 |
| Claverie, JP | 1 |
| Mostert, JW | 1 |
| Evers, JL | 1 |
| Hobika, GH | 1 |
| Moore, RH | 1 |
| Ambrus, JL | 1 |
Reviews
1 review available for fentanyl and Coma
| Article | Year |
|---|---|
Psychogenic coma following upper endoscopy: a case report and review of the literature.
Topics: Adult; Anesthetics, Intravenous; Coma; Endoscopy, Gastrointestinal; Female; Fentanyl; Fundoplication | 2008 |
Other Studies
20 other studies available for fentanyl and Coma
| Article | Year |
|---|---|
Opioid overdoses involving xylazine in emergency department patients: a multicenter study.
Topics: Adult; Analgesics, Opioid; Coma; Drug Overdose; Emergency Service, Hospital; Fentanyl; Humans; Opiat | 2023 |
Fentanyl- and midazolam-induced coma each influence days of mechanical ventilation and 28-day mortality.
Topics: Coma; Fentanyl; Humans; Hypnotics and Sedatives; Midazolam; Respiration, Artificial | 2021 |
Recreational use of carfentanil - a case report with laboratory confirmation.
Topics: Adolescent; Analgesics, Opioid; Coma; Fentanyl; Glasgow Coma Scale; Humans; Illicit Drugs; Male; Tre | 2018 |
Comparison of two sedation regimens during targeted temperature management after cardiac arrest.
Topics: Adult; Aged; Anesthetics, Intravenous; Coma; Deep Sedation; Drug Therapy, Combination; Female; Fenta | 2018 |
Dissecting sedation-induced delirium.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member | 2013 |
Benzodiazepines and delirium: the best option for the right patient.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Coma; Cy | 2013 |
Rapid-onset opioids for the treatment of breakthrough cancer pain: two cases of drug abuse.
Topics: Analgesics, Opioid; Breakthrough Pain; Chemoradiotherapy; Coma; Fentanyl; Gastrointestinal Stromal T | 2014 |
Does this comatose survivor of cardiac arrest have a poor prognosis?
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Body Temperature; Coma; Electrocardiography; Electroen | 2016 |
Letters.
Topics: Administration, Inhalation; Adult; Analgesics, Opioid; Coma; Drug Packaging; Fentanyl; Humans; Male; | 2016 |
Opioid toxicity as a result of oral/transmucosal administration of transdermal fentanyl patch.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Apnea; Coma; Fentanyl; G | 2009 |
Therapeutic hypothermia after cardiac arrest.
Topics: Analgesics; Coma; Fentanyl; Heart Arrest; Humans; Hypnotics and Sedatives; Hypothermia, Induced; Mid | 2011 |
Toxic leukoencephalopathy due to transdermal fentanyl overdose.
Topics: Accidents, Home; Administration, Cutaneous; Apnea; Child, Preschool; Coma; Decerebrate State; Delaye | 2011 |
Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member | 2013 |
A sticky situation: toxicity of clonidine and fentanyl transdermal patches in pediatrics.
Topics: Accidents; Administration, Cutaneous; Analgesics, Opioid; Antihypertensive Agents; Clonidine; Coma; | 2007 |
[Withdrawal syndrome after stopping fentanyl sedation in neurological intensive care].
Topics: Coma; Critical Care; Fentanyl; Humans; Neurologic Examination; Pupil; Substance Withdrawal Syndrome | 1983 |
[Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)].
Topics: Adult; Aged; Anthracenes; Atropine; Benzodiazepines; Buprenorphine; Carticaine; Coma; Delirium; Etom | 1982 |
Acute adverse reaction to fentanyl in a 55 year old man.
Topics: Cerebral Angiography; Chest Pain; Coma; Confusion; Diagnosis, Differential; Drug-Related Side Effect | 2000 |
Acute respiratory arrest and rigidity after anesthesia with sufentanil: a case report.
Topics: Acute Disease; Adult; Anesthesia, General; Anesthetics; Apnea; Coma; Fentanyl; Humans; Male; Muscle | 1985 |
[Role of early care and cerebral lesions in the mortality of young patients with cranial injuries. Preliminary study concerning 92 deaths].
Topics: Adolescent; Adult; Brain Injuries; Child; Child, Preschool; Coma; Female; Fentanyl; Humans; Infant; | 1985 |
Cardiorespiratory effects of anaesthesia with morphine or fentanyl in chronic renal failure and cerebral toxicity after morphine.
Topics: Anesthesia, Intravenous; Blood Pressure; Blood Volume; Carbon Dioxide; Cardiac Output; Coma; Fentany | 1971 |