fentanyl has been researched along with Colitis in 4 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied the analgesic efficacy and side-effect profile of a pH-sensitive fentanyl analog, (±)- N -(3-fluoro-1-phenethylpiperidine-4-yl)- N -phenyl propionamide (NFEPP), during the evolution of colitis induced in mice with dextran sulphate sodium." | 4.31 | Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid. ( Alizadeh, E; Bunnett, NW; Degro, CE; Guzman-Rodriguez, M; Hurlbut, D; Jiménez-Vargas, NN; Lomax, AE; Reed, DE; Stein, C; Tsang, Q; Vanner, SJ; Yu, Y, 2023) |
| "Antinociceptive actions of NFEPP and fentanyl were compared in control mice and mice with dextran sodium sulfate colitis by measuring visceromotor responses to colorectal distension." | 4.12 | Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. ( Bok, DD; Bunnett, NW; Degro, C; Guzman-Rodriguez, M; Jaramillo-Polanco, JO; Jensen, DD; Jiménez-Vargas, NN; Latorre, R; Lomax, AE; Lopez, C; Margolis, KG; Reed, DE; Schmidt, BL; Snow, Z; Stein, C; Tsang, Q; Vanner, SJ; Wisdom, M; Yu, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Degro, CE | 1 |
| Jiménez-Vargas, NN | 2 |
| Tsang, Q | 2 |
| Yu, Y | 2 |
| Guzman-Rodriguez, M | 2 |
| Alizadeh, E | 1 |
| Hurlbut, D | 1 |
| Reed, DE | 2 |
| Lomax, AE | 2 |
| Stein, C | 2 |
| Bunnett, NW | 2 |
| Vanner, SJ | 2 |
| Jensen, DD | 1 |
| Bok, DD | 1 |
| Wisdom, M | 1 |
| Latorre, R | 1 |
| Lopez, C | 1 |
| Jaramillo-Polanco, JO | 1 |
| Degro, C | 1 |
| Snow, Z | 1 |
| Schmidt, BL | 1 |
| Margolis, KG | 1 |
| Ahmed, S | 1 |
| Naumann, DN | 1 |
| Karandikar, S | 1 |
| Gualandi, W | 1 |
| Bonfanti, G | 1 |
4 other studies available for fentanyl and Colitis
| Article | Year |
|---|---|
Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid.
Topics: Analgesics; Analgesics, Opioid; Animals; Colitis; Colon; Fentanyl; Humans; Hydrogen-Ion Concentratio | 2023 |
Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects.
Topics: Animals; Colitis; Colon; Colorectal Neoplasms; Constipation; Fentanyl; Humans; Inflammatory Bowel Di | 2022 |
Differences in screening vs non-screening colonoscopy: scope for improvement?
Topics: Adenoma; Adjuvants, Anesthesia; Aged; Anesthetics, Combined; Butylscopolammonium Bromide; Carcinoma; | 2016 |
[Post-anesthetic bronchospasm].
Topics: Aged; Anesthesia; Benperidol; Bronchial Spasm; Colitis; Female; Fentanyl; Humans; Male; Middle Aged; | 1968 |