fentanyl has been researched along with Aura in 25 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This prospective study evaluated the effects of propofol sedation on the incidence of intraoperative seizures and the adequacy of electrocorticographic (ECoG) recordings during awake craniotomy performed for the management of refractory epilepsy." | 9.08 | Propofol sedation during awake craniotomy for seizures: electrocorticographic and epileptogenic effects. ( Craen, RA; Eliasziw, M; Gelb, AW; Girvin, JP; Herrick, IA; Kirkby, J; McLachlan, RS; Parrent, AG, 1997) |
| "A 6-year-old girl with severe epilepsy received an orthopedic surgery of the right hand under new total intravenous anesthesia with droperidol, fentanyl and ketamine." | 7.68 | [Clinical study on total intravenous anesthesia with droperidol, fentanyl and ketamine--5. An anesthetic experience of a pediatric patient with severe epilepsy]. ( Araki, I; Ishihara, H; Koh, H; Matsuki, A; Shirasaki, S; Takagi, H, 1991) |
| "This prospective study evaluated the effects of propofol sedation on the incidence of intraoperative seizures and the adequacy of electrocorticographic (ECoG) recordings during awake craniotomy performed for the management of refractory epilepsy." | 5.08 | Propofol sedation during awake craniotomy for seizures: electrocorticographic and epileptogenic effects. ( Craen, RA; Eliasziw, M; Gelb, AW; Girvin, JP; Herrick, IA; Kirkby, J; McLachlan, RS; Parrent, AG, 1997) |
| "A 6-year-old girl with severe epilepsy received an orthopedic surgery of the right hand under new total intravenous anesthesia with droperidol, fentanyl and ketamine." | 3.68 | [Clinical study on total intravenous anesthesia with droperidol, fentanyl and ketamine--5. An anesthetic experience of a pediatric patient with severe epilepsy]. ( Araki, I; Ishihara, H; Koh, H; Matsuki, A; Shirasaki, S; Takagi, H, 1991) |
| ", ip) indicate that the liver is the primary site of biotransformation of the compound, suggesting that both 22a and its metabolite(s) are active, compensating probably low bioavailability of the parent molecule." | 1.43 | Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. ( Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E, 2016) |
| "Seizure outcome was graded: I (seizure free without medication), II (seizure free with medication), III (> 50% seizure reduction) or IV (< 50% seizure reduction)." | 1.35 | Anesthesia and electrocorticography for epilepsy surgery: a Jordanian experience. ( Al-Ghanem, SS; Al-Oweidi, AS; Al-Qudah, AA; Tamimi, AF, 2009) |
| "When sevoflurane concentration was reduced to 1." | 1.31 | [Fentanyl administration during sevoflurane anesthesia suppresses spike waves from epileptic focus on electrocorticogram]. ( Asada, A; Koyama, S; Makino, Y; Morino, M; Nishikawa, K; Tanaka, K, 2002) |
| "Propofol has been proposed as a sedative agent during awake craniotomies." | 1.31 | The effect of propofol on intraoperative electrocorticography and cortical stimulation during awake craniotomies in children. ( Black, PM; Eldredge, EA; Kull, L; Madsen, JR; Riviello, JJ; Rockoff, MA; Soriano, SG; Wang, FK, 2000) |
| "Electroencephalographic (EEG) seizures, grouped and isolated spikes, and significant increases of multineuronal activity (MUA) were elicited by fentanyl, 50 micrograms/kg iv, in these brain structures." | 1.29 | Effects of diazepam on fentanyl-induced epileptoid EEG activity and increase of multineuronal firing in limbic and mesencephalic brain structures. ( Antonio-Ocampo, A; Cervantes, M; Chávez-Carrillo, I; Contreras-Gómez, A; Ruelas, R, 1996) |
| " In order to define the minimal dosage of fentanyl required, the MD was titrated according to increases or decreases in the heart rate and/or mean arterial pressure exceeding 15 per cent of baseline ward values." | 1.28 | Anticonvulsant therapy increases fentanyl requirements during anaesthesia for craniotomy. ( Modica, PA; Spitznagel, EL; Tempelhoff, R, 1990) |
| "Fentanyl was administered intravenously at two dose levels (200 micrograms X kg-1, n = 5; and 400 micrograms X kg-1, n = 8)." | 1.27 | Fentanyl-induced seizures activate subcortical brain metabolism. ( Keifer-Goodman, J; Kohlenberger, RW; Maekawa, T; Shapiro, HM; Tommasino, C, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (24.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 9 (36.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Waszkielewicz, AM | 1 |
| Gunia-Krzyżak, A | 1 |
| Powroźnik, B | 1 |
| Słoczyńska, K | 1 |
| Pękala, E | 1 |
| Walczak, M | 1 |
| Bednarski, M | 1 |
| Żesławska, E | 1 |
| Nitek, W | 1 |
| Marona, H | 1 |
| Al-Ghanem, SS | 1 |
| Al-Oweidi, AS | 1 |
| Tamimi, AF | 1 |
| Al-Qudah, AA | 1 |
| Stricker, PA | 1 |
| Kraemer, FW | 1 |
| Ganesh, A | 1 |
| König, MW | 1 |
| Mahmoud, MA | 1 |
| Fujiwara, H | 1 |
| Hemasilpin, N | 1 |
| Lee, KH | 1 |
| Rose, DF | 1 |
| Koyama, S | 1 |
| Makino, Y | 1 |
| Tanaka, K | 1 |
| Morino, M | 1 |
| Nishikawa, K | 1 |
| Asada, A | 1 |
| Szmuk, P | 1 |
| Kee, S | 1 |
| Pivalizza, EG | 1 |
| Warters, RD | 1 |
| Abramson, DC | 1 |
| Ezri, T | 1 |
| Nersesyan, H | 1 |
| Hyder, F | 1 |
| Rothman, DL | 1 |
| Blumenfeld, H | 1 |
| Almeida, AN | 1 |
| Tavares, C | 1 |
| Tibano, A | 1 |
| Sasaki, S | 1 |
| Murata, KN | 1 |
| Marino, R | 1 |
| Jugovac, I | 1 |
| Imas, O | 1 |
| Hudetz, AG | 1 |
| McLachlan, RS | 2 |
| Gloor, P | 1 |
| Avoli, M | 1 |
| Rudehill, A | 1 |
| Gordon, E | 1 |
| Grepe, A | 1 |
| Widén, L | 1 |
| Tommasino, C | 1 |
| Maekawa, T | 1 |
| Shapiro, HM | 1 |
| Keifer-Goodman, J | 1 |
| Kohlenberger, RW | 1 |
| Opitz, A | 1 |
| Marschall, M | 1 |
| Degen, R | 1 |
| Koch, D | 1 |
| Gignac, E | 1 |
| Manninen, PH | 1 |
| Gelb, AW | 2 |
| Cervantes, M | 1 |
| Antonio-Ocampo, A | 1 |
| Ruelas, R | 1 |
| Contreras-Gómez, A | 1 |
| Chávez-Carrillo, I | 1 |
| Herrick, IA | 1 |
| Craen, RA | 1 |
| Girvin, JP | 1 |
| Parrent, AG | 1 |
| Eliasziw, M | 1 |
| Kirkby, J | 1 |
| Decoo, D | 1 |
| Destée, A | 1 |
| Cascino, GD | 1 |
| Velasco, M | 1 |
| Brito, F | 1 |
| Jimenez, F | 1 |
| Gallegos, M | 1 |
| Velasco, AL | 1 |
| Velasco, F | 1 |
| Soriano, SG | 1 |
| Eldredge, EA | 1 |
| Wang, FK | 1 |
| Kull, L | 1 |
| Madsen, JR | 1 |
| Black, PM | 1 |
| Riviello, JJ | 1 |
| Rockoff, MA | 1 |
| Fisher, RS | 1 |
| Frost, JJ | 1 |
| Koh, H | 1 |
| Takagi, H | 1 |
| Araki, I | 1 |
| Shirasaki, S | 1 |
| Ishihara, H | 1 |
| Matsuki, A | 1 |
| Tempelhoff, R | 1 |
| Modica, PA | 1 |
| Spitznagel, EL | 1 |
| Welling, EC | 1 |
| Donegan, J | 1 |
| Brindle, GF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Magnesium Sulphate Versus Fentanyl as Adjuvants to Propofol for Monitored Anesthesia Care During Burr-hole Surgery for Chronic Subdural Hematoma: Randomized Clinical Trial[NCT03854812] | Phase 2 | 32 participants (Actual) | Interventional | 2019-03-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fentanyl and Aura
| Article | Year |
|---|---|
PET studies in epilepsy.
Topics: Brain; Carbon Radioisotopes; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fentanyl; Flumaze | 1997 |
Pharmacological activation.
Topics: Alfentanil; Anesthetics, Intravenous; Convulsants; Electroencephalography; Epilepsy; Fentanyl; Human | 1998 |
Epilepsy.
Topics: Adult; Carbon Radioisotopes; Child; Epilepsy; Fentanyl; Humans; Receptors, Opioid; Tomography, Emiss | 1991 |
2 trials available for fentanyl and Aura
| Article | Year |
|---|---|
Comparison of fentanyl, sufentanil and alfentanil during awake craniotomy for epilepsy.
Topics: Adult; Alfentanil; Anesthesia, Intravenous; Cerebral Cortex; Consciousness; Craniotomy; Double-Blind | 1993 |
Propofol sedation during awake craniotomy for seizures: electrocorticographic and epileptogenic effects.
Topics: Adjuvants, Anesthesia; Adult; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Cerebral Cort | 1997 |
20 other studies available for fentanyl and Aura
| Article | Year |
|---|---|
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Dru | 2016 |
Anesthesia and electrocorticography for epilepsy surgery: a Jordanian experience.
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics; Child; Craniotomy; Electroencephalography; Epil | 2009 |
Severe remifentanil-induced acute opioid tolerance following awake craniotomy in an adolescent.
Topics: Adolescent; Analgesics, Opioid; Anesthesia; Consciousness; Craniotomy; Drug Tolerance; Epilepsy; Fen | 2009 |
Influence of anesthetic management on quality of magnetoencephalography scan data in pediatric patients: a case series.
Topics: Adolescent; Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Intravenous; Artifacts; Child; Child, | 2009 |
[Fentanyl administration during sevoflurane anesthesia suppresses spike waves from epileptic focus on electrocorticogram].
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Anesthetics, Combined; Anesthetics, Inhalation | 2002 |
Anaesthesia for magnetoencephalography in children with intractable seizures.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Child, Preschool; Chloral Hy | 2003 |
Dynamic fMRI and EEG recordings during spike-wave seizures and generalized tonic-clonic seizures in WAG/Rij rats.
Topics: Animals; Bicuculline; Brain Mapping; Cerebral Cortex; Cerebrovascular Circulation; Convulsants; Drop | 2004 |
Dexmedetomidine for awake craniotomy without laryngeal mask.
Topics: Adult; Anesthetics, Combined; Conscious Sedation; Craniotomy; Dexmedetomidine; Epilepsy; Female; Fen | 2005 |
Supraspinal anesthesia: behavioral and electroencephalographic effects of intracerebroventricularly infused pentobarbital, propofol, fentanyl, and midazolam.
Topics: Anesthetics, Intravenous; Animals; Behavior, Animal; Brain; Consciousness; Data Interpretation, Stat | 2006 |
Differential participation of some 'specific' and 'non-specific' thalamic nuclei in generalized spike and wave discharges of feline generalized penicillin epilepsy.
Topics: Animals; Cats; Cerebral Cortex; Computers; Electroencephalography; Epilepsy; Evoked Potentials; Fent | 1984 |
The epileptogenicity of neurolept anaesthesia in patients during and after neuroradiological examinations with metrizamide.
Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Child, Preschool; Electroencephalography; Epilepsy; | 1983 |
Fentanyl-induced seizures activate subcortical brain metabolism.
Topics: Action Potentials; Animals; Autoradiography; Brain; Cerebral Cortex; Dose-Response Relationship, Dru | 1984 |
General anesthesia in patients with epilepsy and status epilepticus.
Topics: Anesthesia, General; Anesthesia, Inhalation; Droperidol; Electroencephalography; Epilepsy; Etomidate | 1983 |
Effects of diazepam on fentanyl-induced epileptoid EEG activity and increase of multineuronal firing in limbic and mesencephalic brain structures.
Topics: Animals; Cats; Diazepam; Electroencephalography; Epilepsy; Fentanyl; Limbic System; Male; Mesencepha | 1996 |
Effect of fentanyl and naloxone on a thalamic induced painful response in intractable epileptic patients.
Topics: Adult; Analgesics, Opioid; Electric Stimulation Therapy; Electrocardiography; Electroencephalography | 1998 |
The effect of propofol on intraoperative electrocorticography and cortical stimulation during awake craniotomies in children.
Topics: Adolescent; Anesthetics, Intravenous; Cerebral Cortex; Child; Cognition; Craniotomy; Electroencephal | 2000 |
[Clinical study on total intravenous anesthesia with droperidol, fentanyl and ketamine--5. An anesthetic experience of a pediatric patient with severe epilepsy].
Topics: Anesthesia, Intravenous; Child; Droperidol; Epilepsy; Female; Fentanyl; Humans; Ketamine; Orthopedic | 1991 |
Anticonvulsant therapy increases fentanyl requirements during anaesthesia for craniotomy.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anticonvulsants; Carbamazepine; Craniotomy; Drug Interac | 1990 |
Neuroleptanalgesia using alfentanil for awake craniotomy.
Topics: Adolescent; Adult; Alfentanil; Awareness; Brain Mapping; Cognition; Consciousness; Epilepsy; Female; | 1989 |
The use of neuroleptic agents in a neurosurgical unit.
Topics: Benperidol; Cerebral Angiography; Chlorpromazine; Craniocerebral Trauma; Electrodes; Epilepsy; Fenta | 1969 |