Page last updated: 2024-10-26

etodolac and Cough

etodolac has been researched along with Cough in 1 studies

Etodolac: A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).
etodolac : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"The effect of etodolac, a potent COX-2 inhibitor, on cough response to inhaled capsaicin was examined in 17 patients with stable asthma in a randomized, placebo-controlled crossover study."9.14COX-2 inhibition attenuates cough reflex sensitivity to inhaled capsaicin in patients with asthma. ( Fujimura, M; Ishiguro, T; Ishiura, Y; Myou, S; Ohkura, N; Yamamoto, H, 2009)
"The effect of etodolac, a potent COX-2 inhibitor, on cough response to inhaled capsaicin was examined in 17 patients with stable asthma in a randomized, placebo-controlled crossover study."5.14COX-2 inhibition attenuates cough reflex sensitivity to inhaled capsaicin in patients with asthma. ( Fujimura, M; Ishiguro, T; Ishiura, Y; Myou, S; Ohkura, N; Yamamoto, H, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishiura, Y1
Fujimura, M1
Yamamoto, H1
Ishiguro, T1
Ohkura, N1
Myou, S1

Trials

1 trial available for etodolac and Cough

ArticleYear
COX-2 inhibition attenuates cough reflex sensitivity to inhaled capsaicin in patients with asthma.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Asthma; Capsaicin; Cough; Cross-Over Studies; Cyclooxygenase 2; Cycl

2009