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endralazine and Hypertension

endralazine has been researched along with Hypertension in 26 studies

*Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. [MeSH]

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199026 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bogers, WA; Holmes, DG; Huunan-Seppala, A; Wideroe, B; Wideroe, TE1
Bogers, WA; Meems, L2
Gerber, W; Pally, C; Salzmann, R; Scholtysik, G1
Reubi, FC; Wegmüller, E1
Hoffmann, JJ; Thien, T; van T'Laar, A1
Blaha, M; Dvorák, I; Dvorák, M; Havlát, F; Kubesová, H; Nĕmcová, H1
Kilic, S1
Fet'kovská, N; Tison, P1
Rawat, R; Seedat, YK1
Elliott, HL; Howden, CW; Lawrie, CB; Meredith, PA; Reid, JL1
Elliott, HL; Meredith, PA; Reid, JL1
Smits, JF; Struyker-Boudier, HA; van Essen, H1
Izotov, AI; Postol'nikov, SF; Vygodin, VA1
Donnelly, RJ; Elliott, HL; McLean, K; Reid, JL; Sumner, DJ1
Elliott, HL; Kelman, AW; McSharry, DR; Meredith, PA; Reid, JL1
Glöckner, WM; Kindler, J; Konrads, A; Meurer, KA; Schulz, V; Sieberth, HG; Vaith, P1
Hochrein, H; Lehmann, HU; Meyer-Estorf, G1
Hochrein, H; Lehmann, HU; Witt, E1
Hartmann, HG; Schumacher, H1
McGourty, JC; Pidgeon, J; Silas, JH1
Chazan, BI; Duff, DA; McCallum, A; Whaley, K1
Hauger-Klevene, JH; Mayer, E; Reader, C; Sanchez, MR1
Izotov, AI; Malysheva, NV; Postol'nikov, SF1
Carruthers, SG; Spence, JD; Wu, R1
Kindler, J; Moedder, G; Sieberth, HG1

Trials

11 trial(s) available for endralazine and Hypertension

ArticleYear
Endralazine, a new peripheral vasodilator: absence of effect of acetylator status on antihypertensive effect.
    Lancet (London, England), 1983, Mar-26, Volume: 1, Issue:8326 Pt 1

    Topics: Acetylation; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Genes; Humans; Hydralazine; Hydrazones; Hypertension; Male; Pindolol; Pyridazines

1983
[Experience with endralazine in the treatment of essential hypertension].
    Vnitrni lekarstvi, 1984, Volume: 30, Issue:1

    Topics: Antihypertensive Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pyridazines

1984
[Systolic hypertension. Treatment with endralazine].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1983, Dec-10, Volume: 59, Issue:34

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Pyridazines; Systole

1983
[Endralazine in the treatment of hypertension].
    Vnitrni lekarstvi, 1984, Volume: 30, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Pyridazines

1984
A dose-finding study of the combination of pindolol, clopamide and endralazine in the treatment of moderate-to-severe hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Nov-03, Volume: 66, Issue:18

    Topics: Antihypertensive Agents; Clinical Trials as Topic; Clopamide; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Pindolol; Pyridazines; Time Factors

1984
[Methodologic approach to individual evaluation of the pharmacodynamic effects of single doses of hydralazine, endralazine, prazosine and propranolol in hypertension patients].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1984, Volume: 7, Issue:1

    Topics: Adult; Antihypertensive Agents; Cardiac Output; Cardiography, Impedance; Humans; Hydralazine; Hypertension; Kinetics; Middle Aged; Prazosin; Propranolol; Pyridazines; Vascular Resistance

1984
[Management of treatment-resistant hypertension: comparison of the antihypertensive effect of endralazine and minoxidil (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Sep-11, Volume: 106, Issue:37

    Topics: Adolescent; Adult; Aged; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Minoxidil; Pyridazines; Pyrimidines; Sleep Wake Disorders

1981
Comparison of once daily endralazine with placebo in the treatment of hypertension uncontrolled by a beta-blocker and diuretic.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Placebos; Posture; Pyridazines; Random Allocation; Time Factors

1985
Comparative study of endralazine and hydralazine for the treatment of hypertension uncontrolled by a beta-blocker and diuretic.
    Current medical research and opinion, 1986, Volume: 10, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antibodies, Antinuclear; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Pyridazines; Random Allocation

1986
A comparative study of endralazine and captopril in essential hypertension: effect on renin levels, pulmonary function studies and lipid profile.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Captopril; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Pyridazines; Random Allocation; Renin; Respiratory Function Tests

1986
[Endralazine monotherapy in comparison with prazosin and hydralazine in arterial hypertension].
    Sovetskaia meditsina, 1986, Issue:10

    Topics: Adult; Clinical Trials as Topic; Humans; Hydralazine; Hypertension; Male; Middle Aged; Prazosin; Pyridazines

1986

Other Studies

15 other study(ies) available for endralazine and Hypertension

ArticleYear
Endralazine and acetylator phenotype.
    Lancet (London, England), 1983, May-28, Volume: 1, Issue:8335

    Topics: Acetylation; Antihypertensive Agents; Humans; Hypertension; Phenotype; Pyridazines

1983
Effects of the vasodilator endralazine given with the antihypertensive agent guanfacine on heart rate and blood pressure of spontaneously hypertensive rats and normotensive dogs.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:5

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Drug Therapy, Combination; Guanfacine; Guanidines; Heart Rate; Hypertension; Male; Phenylacetates; Pyridazines; Rats; Rats, Inbred Strains; Vasodilator Agents

1983
Changes in renal function induced by endralazine, a new antihypertensive drug.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Middle Aged; Natriuresis; Potassium; Pyridazines; Renal Circulation; Renin; Urea

1983
Effects of intravenous endralazine in essential hypertension.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Pyridazines; Renin; Time Factors

1983
Clinical pharmacological studies with the vasodilator endralazine in normotensive subjects and essential hypertensives.
    International journal of clinical pharmacology research, 1984, Volume: 4, Issue:1

    Topics: Adult; Blood Pressure; Heart Rate; Humans; Hypertension; Kinetics; Male; Pyridazines; Vasodilator Agents

1984
Pharmacodynamic and pharmacokinetic studies with the vasodilator endralazine.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Adult; Blood Pressure; Drug Evaluation; Humans; Hypertension; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Pyridazines; Random Allocation; Time Factors; Vasodilator Agents

1984
Hemodynamic effects of the arteriolar vasodilators hydralazine, dihydralazine and endralazine in the conscious spontaneously hypertensive rat.
    European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4

    Topics: Animals; Denervation; Dihydralazine; Hemodynamics; Hydralazine; Hypertension; Male; Pressoreceptors; Pyridazines; Rats; Vasodilator Agents

1983
Clinical evaluation of endralazine (BO22708), a new vasodilator, in essential hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:8

    Topics: Adult; Aged; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Pyridazines; Renin; Vasodilator Agents

1982
Endralazine, a new peripheral vasodilator. Evaluation of safety and efficacy over a 3 year period.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:3

    Topics: Acetylation; Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Phenotype; Pindolol; Pyridazines; Time Factors; Vasodilator Agents

1983
The pharmacokinetics of endralazine in essential hypertensives and in normotensive subjects.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:1

    Topics: Acetylation; Administration, Oral; Aged; Antihypertensive Agents; Female; Humans; Hypertension; Injections, Intravenous; Kinetics; Male; Middle Aged; Pyridazines

1983
[Clinical effectiveness of BQ 22-708, a pyridopyridazine derivative, in the treatment of fixed essential hypertension].
    Die Medizinische Welt, 1978, Jun-16, Volume: 29, Issue:24

    Topics: Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Pyridazines

1978
[Evaluation of a pyridopyridazine as a drug with marked antihypertensive properties (author's transl)].
    Medizinische Klinik, 1977, Jul-15, Volume: 72, Issue:28-29

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Capillaries; Cardiac Output; Female; Heart Failure; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pulmonary Artery; Pyridazines; Vascular Resistance

1977
[Antihypertensive pharmacotherapy with the vasodilators captopril and endralazine].
    Schweizerische medizinische Wochenschrift, 1985, Jul-09, Volume: 115, Issue:27-28

    Topics: Adrenergic beta-Antagonists; Adult; Captopril; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Proline; Pyridazines; Vasodilator Agents

1985
Evaluation of once daily endralazine in hypertension.
    European journal of clinical pharmacology, 1986, Volume: 30, Issue:5

    Topics: Acetylation; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Pyridazines

1986
Tissue distribution of endralazine and its clinical effect in refractory hypertension.
    Contributions to nephrology, 1985, Volume: 49

    Topics: Animals; Antihypertensive Agents; Autoradiography; Blood Pressure; Carbon Radioisotopes; Clonidine; Female; Humans; Hypertension; Hypertension, Renal; Male; Mice; Pregnancy; Prospective Studies; Pyridazines; Tissue Distribution

1985
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