Page last updated: 2024-10-30

edaravone and Aging

edaravone has been researched along with Aging in 8 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The findings suggest that aging leads to altered disposition of antipyrine in both males and females and that the main metabolic pathways of the compound are not different in the elderly."3.70The effect of age and sex on metabolism and urinary excretion of antipyrine. ( Almar, M; González-Gallego, J; González-Sastre, M; Jorquera, F; Pozuelo, M; Sansegundo, D, 1998)
" The first three months of life were characterised by a steady decrease in the apparent volume of distribution (aVd) and half-life (t0."1.29Effect of age on the pharmacokinetics of antipyrine in calves. ( Janus, K; Suszycka, J, 1996)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Zhou, Y1
Wu, X1
Ye, L1
Bai, Y1
Zhang, H1
Xuan, Z1
Feng, Y1
Zhang, P1
Chen, Y1
Yan, Y1
Zhu, B1
Cui, W1
Wu, CY1
Zha, H1
Xia, QQ1
Yuan, Y1
Liang, XY1
Li, JH1
Guo, ZY1
Li, JJ1
Wen, J2
Watanabe, K2
Ma, M2
Yamaguchi, K1
Tachikawa, H1
Kodama, M2
Aizawa, Y2
Janus, K1
Suszycka, J1
Jorquera, F1
Almar, M1
Pozuelo, M1
Sansegundo, D1
González-Sastre, M1
González-Gallego, J1
Waite, NM1
Rybak, MJ1
Krakovsky, DJ1
Steinberg, JD1
Warbasse, LH1
Edwards, DJ1
Van Geel, CA1
Van Bezooijen, CF1

Trials

1 trial available for edaravone and Aging

ArticleYear
Influence of subject age on the inhibition of oxidative metabolism by ciprofloxacin.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Antipyrine; Ciprofloxacin; Edaravone; Female; Humans; Male; O

1991

Other Studies

7 other studies available for edaravone and Aging

ArticleYear
Edaravone at high concentrations attenuates cognitive dysfunctions induced by abdominal surgery under general anesthesia in aged mice.
    Metabolic brain disease, 2020, Volume: 35, Issue:2

    Topics: Abdominal Wall; Aging; Anesthesia, General; Animals; Cognitive Dysfunction; Dose-Response Relationsh

2020
Expression of angiotensin II and its receptors in activated microglia in experimentally induced cerebral ischemia in the adult rats.
    Molecular and cellular biochemistry, 2013, Volume: 382, Issue:1-2

    Topics: Aging; Angiotensin II; Animals; Antipyrine; Blotting, Western; Brain Ischemia; Cerebral Cortex; Edar

2013
Edaravone inhibits JNK-c-Jun pathway and restores anti-oxidative defense after ischemia-reperfusion injury in aged rats.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:4

    Topics: Aging; Animals; Antioxidants; Antipyrine; Blotting, Western; Brain; Cerebral Infarction; Edaravone;

2006
Effects of edaravone in heart of aged rats after cerebral ischemia-reperfusion injury.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3

    Topics: Aging; Animals; Antipyrine; Apoptosis; Blotting, Western; Brain Ischemia; Cell Survival; Disease Mod

2007
Effect of age on the pharmacokinetics of antipyrine in calves.
    Research in veterinary science, 1996, Volume: 60, Issue:3

    Topics: Aging; Animals; Antipyrine; Cattle; Edaravone; Female; Half-Life; Metabolic Clearance Rate; Time Fac

1996
The effect of age and sex on metabolism and urinary excretion of antipyrine.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1998, Volume: 53, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal

1998
The effect of age on the oxidative metabolism of antipyrine by uninduced microsomal fractions of rat liver.
    Mechanisms of ageing and development, 1990, Apr-09, Volume: 53, Issue:2

    Topics: Aging; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Edaravone; In Vitro Techniques; Isoenzym

1990