edaravone and Aging
edaravone has been researched along with Aging in 8 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The findings suggest that aging leads to altered disposition of antipyrine in both males and females and that the main metabolic pathways of the compound are not different in the elderly." | 3.70 | The effect of age and sex on metabolism and urinary excretion of antipyrine. ( Almar, M; González-Gallego, J; González-Sastre, M; Jorquera, F; Pozuelo, M; Sansegundo, D, 1998) |
| " The first three months of life were characterised by a steady decrease in the apparent volume of distribution (aVd) and half-life (t0." | 1.29 | Effect of age on the pharmacokinetics of antipyrine in calves. ( Janus, K; Suszycka, J, 1996) |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Zhou, Y | 1 |
| Wu, X | 1 |
| Ye, L | 1 |
| Bai, Y | 1 |
| Zhang, H | 1 |
| Xuan, Z | 1 |
| Feng, Y | 1 |
| Zhang, P | 1 |
| Chen, Y | 1 |
| Yan, Y | 1 |
| Zhu, B | 1 |
| Cui, W | 1 |
| Wu, CY | 1 |
| Zha, H | 1 |
| Xia, QQ | 1 |
| Yuan, Y | 1 |
| Liang, XY | 1 |
| Li, JH | 1 |
| Guo, ZY | 1 |
| Li, JJ | 1 |
| Wen, J | 2 |
| Watanabe, K | 2 |
| Ma, M | 2 |
| Yamaguchi, K | 1 |
| Tachikawa, H | 1 |
| Kodama, M | 2 |
| Aizawa, Y | 2 |
| Janus, K | 1 |
| Suszycka, J | 1 |
| Jorquera, F | 1 |
| Almar, M | 1 |
| Pozuelo, M | 1 |
| Sansegundo, D | 1 |
| González-Sastre, M | 1 |
| González-Gallego, J | 1 |
| Waite, NM | 1 |
| Rybak, MJ | 1 |
| Krakovsky, DJ | 1 |
| Steinberg, JD | 1 |
| Warbasse, LH | 1 |
| Edwards, DJ | 1 |
| Van Geel, CA | 1 |
| Van Bezooijen, CF | 1 |
Trials
1 trial available for edaravone and Aging
| Article | Year |
|---|---|
Influence of subject age on the inhibition of oxidative metabolism by ciprofloxacin.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antipyrine; Ciprofloxacin; Edaravone; Female; Humans; Male; O | 1991 |
Other Studies
7 other studies available for edaravone and Aging
| Article | Year |
|---|---|
Edaravone at high concentrations attenuates cognitive dysfunctions induced by abdominal surgery under general anesthesia in aged mice.
Topics: Abdominal Wall; Aging; Anesthesia, General; Animals; Cognitive Dysfunction; Dose-Response Relationsh | 2020 |
Expression of angiotensin II and its receptors in activated microglia in experimentally induced cerebral ischemia in the adult rats.
Topics: Aging; Angiotensin II; Animals; Antipyrine; Blotting, Western; Brain Ischemia; Cerebral Cortex; Edar | 2013 |
Edaravone inhibits JNK-c-Jun pathway and restores anti-oxidative defense after ischemia-reperfusion injury in aged rats.
Topics: Aging; Animals; Antioxidants; Antipyrine; Blotting, Western; Brain; Cerebral Infarction; Edaravone; | 2006 |
Effects of edaravone in heart of aged rats after cerebral ischemia-reperfusion injury.
Topics: Aging; Animals; Antipyrine; Apoptosis; Blotting, Western; Brain Ischemia; Cell Survival; Disease Mod | 2007 |
Effect of age on the pharmacokinetics of antipyrine in calves.
Topics: Aging; Animals; Antipyrine; Cattle; Edaravone; Female; Half-Life; Metabolic Clearance Rate; Time Fac | 1996 |
The effect of age and sex on metabolism and urinary excretion of antipyrine.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal | 1998 |
The effect of age on the oxidative metabolism of antipyrine by uninduced microsomal fractions of rat liver.
Topics: Aging; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Edaravone; In Vitro Techniques; Isoenzym | 1990 |