Page last updated: 2024-10-26

doxapram and Birth Weight

doxapram has been researched along with Birth Weight in 5 studies

Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.

Birth Weight: The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Fifteen infants, median gestational age at birth 27 weeks (range 24-30), age at study 27 days (12-60), with >/=6 episodes of bradycardia or hypoxaemia/6 h despite serum caffeine levels in the therapeutic range, received doxapram either intravenously (0."9.09Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants. ( Bohnhorst, B; Darraj, S; Poets, CF, 1999)
"Twelve premature infants with significant apnea of prematurity while receiving therapeutic doses of aminophylline were given an intravenous infusion of doxapram, 2 or 2."7.67Physiologic effects of doxapram in idiopathic apnea of prematurity. ( Barrington, KJ; Barton, J; Finer, NN; Peters, KL, 1986)
"Fifteen infants, median gestational age at birth 27 weeks (range 24-30), age at study 27 days (12-60), with >/=6 episodes of bradycardia or hypoxaemia/6 h despite serum caffeine levels in the therapeutic range, received doxapram either intravenously (0."5.09Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants. ( Bohnhorst, B; Darraj, S; Poets, CF, 1999)
"Doxapram is a treatment option for severe apnea of prematurity (AOP)."3.91Doxapram Treatment and Diaphragmatic Activity in Preterm Infants. ( de Jongh, FH; de Waal, CG; Hutten, GJ; Kraaijenga, JV; van Kaam, AH, 2019)
"Doxapram is a respiratory stimulant widely used for the treatment of idiopathic apnea of prematurity, although it has been demonstrated that it can induce a transient decrease of cerebral blood flow and that isolated mental delay in infants weighing <1,250 g is associated with the total dosage and duration of doxapram therapy."3.73Brain hemodynamic effects of doxapram in preterm infants. ( Bertini, G; Dani, C; Filippi, L; Pezzati, M; Pratesi, S; Rubaltelli, FF; Tronchin, M, 2006)
"Twelve premature infants with significant apnea of prematurity while receiving therapeutic doses of aminophylline were given an intravenous infusion of doxapram, 2 or 2."3.67Physiologic effects of doxapram in idiopathic apnea of prematurity. ( Barrington, KJ; Barton, J; Finer, NN; Peters, KL, 1986)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Waal, CG1
Hutten, GJ1
Kraaijenga, JV1
de Jongh, FH1
van Kaam, AH1
Dani, C1
Bertini, G1
Pezzati, M1
Pratesi, S1
Filippi, L1
Tronchin, M1
Rubaltelli, FF1
Poets, CF1
Darraj, S1
Bohnhorst, B1
Barrington, KJ1
Finer, NN1
Peters, KL1
Barton, J1
Gupta, PK1
Moore, J1

Trials

1 trial available for doxapram and Birth Weight

ArticleYear
Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants.
    Biology of the neonate, 1999, Volume: 76, Issue:4

    Topics: Apnea; Birth Weight; Bradycardia; Caffeine; Doxapram; Drug Resistance; Gestational Age; Humans; Hypo

1999

Other Studies

4 other studies available for doxapram and Birth Weight

ArticleYear
Doxapram Treatment and Diaphragmatic Activity in Preterm Infants.
    Neonatology, 2019, Volume: 115, Issue:1

    Topics: Apnea; Birth Weight; Diaphragm; Doxapram; Electromyography; Female; Gestational Age; Humans; Infant,

2019
Brain hemodynamic effects of doxapram in preterm infants.
    Biology of the neonate, 2006, Volume: 89, Issue:2

    Topics: Apnea; Birth Weight; Blood Flow Velocity; Brain; Case-Control Studies; Doxapram; Gestational Age; Hu

2006
Physiologic effects of doxapram in idiopathic apnea of prematurity.
    The Journal of pediatrics, 1986, Volume: 108, Issue:1

    Topics: Aminophylline; Apnea; Birth Weight; Blood Pressure; Carbon Dioxide; Doxapram; Gestational Age; Human

1986
The use of doxapram in the newborn.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1973, Volume: 80, Issue:11

    Topics: Anesthesia, Obstetrical; Bicarbonates; Birth Weight; Blood; Carbon Dioxide; Doxapram; Female; Gestat

1973
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