donepezil and Amblyopia
donepezil has been researched along with Amblyopia in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Amblyopia: A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil dosage was started at 2." | 7.30 | Durable recovery from amblyopia with donepezil. ( Gaier, ED; Hensch, TK; Hunter, DG; Nihalani, BR; Whitecross, S; Wu, C, 2023) |
| "Donepezil dosage was started at 2." | 3.30 | Durable recovery from amblyopia with donepezil. ( Gaier, ED; Hensch, TK; Hunter, DG; Nihalani, BR; Whitecross, S; Wu, C, 2023) |
| "Amblyopia is a developmental brain disorder in which vision is lost due to asymmetric or inadequate visual stimulation early in life." | 2.53 | Medical Therapies of Amblyopia: Translational Research to Expand Our Treatment Armamentarium. ( Gore, C; Wu, C, 2016) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Wu, C | 2 |
| Gaier, ED | 1 |
| Nihalani, BR | 1 |
| Whitecross, S | 1 |
| Hensch, TK | 1 |
| Hunter, DG | 1 |
| Gore, C | 1 |
Reviews
1 review available for donepezil and Amblyopia
| Article | Year |
|---|---|
Medical Therapies of Amblyopia: Translational Research to Expand Our Treatment Armamentarium.
Topics: Amblyopia; Carbidopa; Cholinesterase Inhibitors; Donepezil; Dopamine Agonists; Drug Combinations; Fl | 2016 |
Trials
1 trial available for donepezil and Amblyopia
| Article | Year |
|---|---|
Durable recovery from amblyopia with donepezil.
Topics: Acetylcholinesterase; Amblyopia; Animals; Donepezil; Mice; Visual Acuity | 2023 |