donepezil has been researched along with Alogia in 6 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study explored the feasibility and effectiveness of a short-term (10-week) intervention trial using Donepezil administered alone and combined with intensive language action therapy (ILAT) for the treatment of apathy and depression in ten people with chronic post-stroke aphasia." | 9.69 | Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study. ( Berthier, ML; Dávila, G; Edelkraut, L; Jorge, RE; López-Barroso, D; López-González, FJ; Mohr, B; Pulvermüller, F; Starkstein, SE; Torres-Prioris, MJ, 2023) |
| "We studied 26 patients in a randomized, placebo-controlled, double-blind parallel trial to evaluate the efficacy and safety of donepezil in chronic poststroke aphasia." | 9.12 | A randomized, placebo-controlled study of donepezil in poststroke aphasia. ( Berthier, ML; Fernández, I; Green, C; Higueras, C; Hinojosa, J; Martín, MC, 2006) |
| "This study explored the feasibility and effectiveness of a short-term (10-week) intervention trial using Donepezil administered alone and combined with intensive language action therapy (ILAT) for the treatment of apathy and depression in ten people with chronic post-stroke aphasia." | 5.69 | Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study. ( Berthier, ML; Dávila, G; Edelkraut, L; Jorge, RE; López-Barroso, D; López-González, FJ; Mohr, B; Pulvermüller, F; Starkstein, SE; Torres-Prioris, MJ, 2023) |
| "We studied 26 patients in a randomized, placebo-controlled, double-blind parallel trial to evaluate the efficacy and safety of donepezil in chronic poststroke aphasia." | 5.12 | A randomized, placebo-controlled study of donepezil in poststroke aphasia. ( Berthier, ML; Fernández, I; Green, C; Higueras, C; Hinojosa, J; Martín, MC, 2006) |
| "Pharmacotherapy of aphasia had been discussed for the last twenty years with first bromocriptine and amphetamine and then serotoninergic, GABAergic and cholinergic agents." | 4.84 | Pharmacotherapy of aphasia: myth or reality? ( de Boissezon, X; de Boysson, C; Démonet, JF; Peran, P, 2007) |
| "Donepezil has a significant effect in improving the ability of auditory comprehension, naming, repetition and oral expression." | 2.58 | The Efficacy and Safety of Pharmacological Treatments for Post-stroke Aphasia. ( Du, G; Fu, Q; Huang, L; Shu, B; Zhang, D; Zhang, X, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Swenson, TL | 1 |
| Roehmer, C | 1 |
| Tran, R | 1 |
| Plummer, C | 1 |
| Berthier, ML | 4 |
| Edelkraut, L | 2 |
| López-González, FJ | 2 |
| López-Barroso, D | 2 |
| Mohr, B | 2 |
| Pulvermüller, F | 2 |
| Starkstein, SE | 2 |
| Jorge, RE | 2 |
| Torres-Prioris, MJ | 2 |
| Dávila, G | 2 |
| Zhang, X | 1 |
| Shu, B | 1 |
| Zhang, D | 1 |
| Huang, L | 1 |
| Fu, Q | 1 |
| Du, G | 1 |
| Hinojosa, J | 2 |
| Martín, Mdel C | 1 |
| Fernández, I | 2 |
| de Boissezon, X | 1 |
| Peran, P | 1 |
| de Boysson, C | 1 |
| Démonet, JF | 1 |
| Green, C | 1 |
| Higueras, C | 1 |
| Martín, MC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Combining Donepezil, Intensive Language Rehabilitation and Transcranial Direct Current Stimulation on Language Recovery and Brain Reorganization in Chronic Post-stroke Aphasia[NCT04134416] | Phase 3 | 20 participants (Actual) | Interventional | 2019-01-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for donepezil and Alogia
| Article | Year |
|---|---|
The Efficacy and Safety of Pharmacological Treatments for Post-stroke Aphasia.
Topics: Aphasia; Databases, Factual; Donepezil; Humans; Memantine; Nootropic Agents; Stroke | 2018 |
Pharmacotherapy of aphasia: myth or reality?
Topics: Amphetamine; Aphasia; Bromocriptine; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; | 2007 |
2 trials available for donepezil and Alogia
| Article | Year |
|---|---|
Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study.
Topics: Apathy; Aphasia; Depression; Donepezil; Feasibility Studies; Humans; Language; Language Therapy; Tre | 2023 |
Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study.
Topics: Apathy; Aphasia; Depression; Donepezil; Feasibility Studies; Humans; Language; Language Therapy; Tre | 2023 |
Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study.
Topics: Apathy; Aphasia; Depression; Donepezil; Feasibility Studies; Humans; Language; Language Therapy; Tre | 2023 |
Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study.
Topics: Apathy; Aphasia; Depression; Donepezil; Feasibility Studies; Humans; Language; Language Therapy; Tre | 2023 |
A randomized, placebo-controlled study of donepezil in poststroke aphasia.
Topics: Acetylcholine; Adult; Aphasia; Brain; Cerebrovascular Circulation; Donepezil; Double-Blind Method; F | 2006 |
2 other studies available for donepezil and Alogia
| Article | Year |
|---|---|
Donepezil for Aphasia After Severe Traumatic Brain Injury: A Clinical Vignette.
Topics: Aphasia; Brain Injuries, Traumatic; Donepezil; Humans | 2022 |
Open-label study of donepezil in chronic poststroke aphasia.
Topics: Adult; Aged; Aphasia; Cholinesterase Inhibitors; Chronic Disease; Donepezil; Female; Humans; Indans; | 2003 |