donepezil has been researched along with ADDH in 11 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This review discusses the laboratory and clinical research supporting the rationale for the efficacy of donepezil (Aricept USA) in enhancing cognition in autism, Alzheimer disease, Down syndrome, traumatic brain injury, Attention Deficit Hyperactivity Disorder (ADHD), and schizophrenia." | 4.84 | Relevance of donepezil in enhancing learning and memory in special populations: a review of the literature. ( Valdovinos, MG; Williams, DC; Yoo, JH, 2007) |
| "Donepezil 5 and 10 mg were not well tolerated in these children and adolescents." | 2.73 | Donepezil use in children and adolescents with tics and attention-deficit/hyperactivity disorder: an 18-week, single-center, dose-escalating, prospective, open-label study. ( Anaya, B; Cubo, E; Fernández Jaén, A; González, M; Kompoliti, K; Moreno, C, 2008) |
| "Clonidine is a good option for managing core behavioral symptoms, especially hyperactivity and impulsivity." | 2.43 | Advances in alternative pharmacotherapy of ADHD. ( Pityaratstian, N, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 9 (81.82) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rezvani, AH | 1 |
| Cauley, MC | 1 |
| Johnson, EC | 1 |
| Gatto, GJ | 1 |
| Levin, ED | 1 |
| Schweitzer, JB | 1 |
| Holcomb, HH | 1 |
| Pachaiyappan, K | 1 |
| Petti, TA | 1 |
| Bangs, M | 1 |
| Pfau, B | 1 |
| Dumlao, S | 1 |
| Wilens, TE | 2 |
| Waxmonsky, J | 1 |
| Scott, M | 1 |
| Swezey, A | 1 |
| Kwon, A | 1 |
| Spencer, TJ | 3 |
| Biederman, J | 3 |
| Doyle, RL | 1 |
| Frazier, J | 1 |
| Geller, D | 1 |
| Wilens, T | 1 |
| Pityaratstian, N | 1 |
| Yoo, JH | 1 |
| Valdovinos, MG | 1 |
| Williams, DC | 1 |
| Cubo, E | 1 |
| Fernández Jaén, A | 1 |
| Moreno, C | 1 |
| Anaya, B | 1 |
| González, M | 1 |
| Kompoliti, K | 1 |
| Hoopes, SP | 1 |
| Wong, J | 1 |
| Prince, JB | 1 |
| Horrigan, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Examination of Galantamine in the Management of Tic Disorders[NCT00226824] | Phase 4 | 1 participants (Actual) | Interventional | 2005-09-30 | Terminated (stopped due to Unable to recruit subjects into the trial.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for donepezil and ADDH
| Article | Year |
|---|---|
Drugs under investigation for attention-deficit hyperactivity disorder.
Topics: Animals; Antidepressive Agents; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperacti | 2002 |
Advances in alternative pharmacotherapy of ADHD.
Topics: Adrenergic alpha-Agonists; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperac | 2005 |
Relevance of donepezil in enhancing learning and memory in special populations: a review of the literature.
Topics: Alzheimer Disease; Animals; Attention; Attention Deficit Disorder with Hyperactivity; Autistic Disor | 2007 |
Present and future pharmacotherapeutic options for adult attention deficit/hyperactivity disorder.
Topics: Adult; Amphetamines; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central N | 2001 |
2 trials available for donepezil and ADDH
| Article | Year |
|---|---|
Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Development Disorders, Perva | 2006 |
Donepezil use in children and adolescents with tics and attention-deficit/hyperactivity disorder: an 18-week, single-center, dose-escalating, prospective, open-label study.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cholinesterase Inhibitors; Comorbi | 2008 |
5 other studies available for donepezil and ADDH
| Article | Year |
|---|---|
Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Disease Models, Animal; Di | 2012 |
Urinary incontinence with donepezil treatment in hospitalized children and adolescents with attention deficit hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cholinesterase Inhibitors; Donepez | 2003 |
An open trial of adjunctive donepezil in attention-deficit/hyperactivity disorder.
Topics: Adolescent; Adult; Amphetamines; Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Ch | 2005 |
Donepezil for Tourette's disorder and ADHD.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Comorbidity; Donepezil; Humans; In | 1999 |
Adjunctive donepezil in attention deficit hyperactivity disorder youth: case series.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cholinesterase Inhibitors; Donepez | 2000 |