Page last updated: 2024-10-26

donepezil and ADDH

donepezil has been researched along with ADDH in 11 studies

Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.

Research Excerpts

ExcerptRelevanceReference
"This review discusses the laboratory and clinical research supporting the rationale for the efficacy of donepezil (Aricept USA) in enhancing cognition in autism, Alzheimer disease, Down syndrome, traumatic brain injury, Attention Deficit Hyperactivity Disorder (ADHD), and schizophrenia."4.84Relevance of donepezil in enhancing learning and memory in special populations: a review of the literature. ( Valdovinos, MG; Williams, DC; Yoo, JH, 2007)
"Donepezil 5 and 10 mg were not well tolerated in these children and adolescents."2.73Donepezil use in children and adolescents with tics and attention-deficit/hyperactivity disorder: an 18-week, single-center, dose-escalating, prospective, open-label study. ( Anaya, B; Cubo, E; Fernández Jaén, A; González, M; Kompoliti, K; Moreno, C, 2008)
"Clonidine is a good option for managing core behavioral symptoms, especially hyperactivity and impulsivity."2.43Advances in alternative pharmacotherapy of ADHD. ( Pityaratstian, N, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's9 (81.82)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rezvani, AH1
Cauley, MC1
Johnson, EC1
Gatto, GJ1
Levin, ED1
Schweitzer, JB1
Holcomb, HH1
Pachaiyappan, K1
Petti, TA1
Bangs, M1
Pfau, B1
Dumlao, S1
Wilens, TE2
Waxmonsky, J1
Scott, M1
Swezey, A1
Kwon, A1
Spencer, TJ3
Biederman, J3
Doyle, RL1
Frazier, J1
Geller, D1
Wilens, T1
Pityaratstian, N1
Yoo, JH1
Valdovinos, MG1
Williams, DC1
Cubo, E1
Fernández Jaén, A1
Moreno, C1
Anaya, B1
González, M1
Kompoliti, K1
Hoopes, SP1
Wong, J1
Prince, JB1
Horrigan, JP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Examination of Galantamine in the Management of Tic Disorders[NCT00226824]Phase 41 participants (Actual)Interventional2005-09-30Terminated (stopped due to Unable to recruit subjects into the trial.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for donepezil and ADDH

ArticleYear
Drugs under investigation for attention-deficit hyperactivity disorder.
    Current opinion in investigational drugs (London, England : 2000), 2002, Volume: 3, Issue:8

    Topics: Animals; Antidepressive Agents; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperacti

2002
Advances in alternative pharmacotherapy of ADHD.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88 Suppl 4

    Topics: Adrenergic alpha-Agonists; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperac

2005
Relevance of donepezil in enhancing learning and memory in special populations: a review of the literature.
    Journal of autism and developmental disorders, 2007, Volume: 37, Issue:10

    Topics: Alzheimer Disease; Animals; Attention; Attention Deficit Disorder with Hyperactivity; Autistic Disor

2007
Present and future pharmacotherapeutic options for adult attention deficit/hyperactivity disorder.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:4

    Topics: Adult; Amphetamines; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central N

2001

Trials

2 trials available for donepezil and ADDH

ArticleYear
Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series.
    Journal of attention disorders, 2006, Volume: 9, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Development Disorders, Perva

2006
Donepezil use in children and adolescents with tics and attention-deficit/hyperactivity disorder: an 18-week, single-center, dose-escalating, prospective, open-label study.
    Clinical therapeutics, 2008, Volume: 30, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cholinesterase Inhibitors; Comorbi

2008

Other Studies

5 other studies available for donepezil and ADDH

ArticleYear
Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats.
    Psychopharmacology, 2012, Volume: 223, Issue:3

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Disease Models, Animal; Di

2012
Urinary incontinence with donepezil treatment in hospitalized children and adolescents with attention deficit hyperactivity disorder.
    Journal of child and adolescent psychopharmacology, 2003,Spring, Volume: 13, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cholinesterase Inhibitors; Donepez

2003
An open trial of adjunctive donepezil in attention-deficit/hyperactivity disorder.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Amphetamines; Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Ch

2005
Donepezil for Tourette's disorder and ADHD.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:4

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Comorbidity; Donepezil; Humans; In

1999
Adjunctive donepezil in attention deficit hyperactivity disorder youth: case series.
    Journal of child and adolescent psychopharmacology, 2000,Fall, Volume: 10, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cholinesterase Inhibitors; Donepez

2000