domperidone has been researched along with Cough in 7 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and safety of baclofen for treatment of refractory gastroesophageal reflux-induced chronic cough (GERC) unresponsive to standard anti-reflux therapy." | 7.79 | Therapeutic efficacy of baclofen in refractory gastroesophageal reflux-induced chronic cough. ( Chen, Q; Liang, SW; Lv, HJ; Qiu, ZM; Xu, XH; Yang, ZM; Yu, L, 2013) |
| "In a complex seven-period cross-over trial to study the effects of a drug in attenuating capsaicin-induced coughing, counts of numbers of coughs were recorded 32 times in each period." | 7.71 | Dynamic modelling of a challenge-escalation cross-over study of treatment of capsaicin-induced coughing. ( Jackson, D; Jones, B; Lindsey, JK; Stevens, JW, 2002) |
| "Clinical symptoms, cough symptom score, capsaicin cough sensitivity, gastroesophageal reflux diagnostic questionnaire (GerdQ) score, findings of multichannel intraluminal impedance-pH monitoring (MII-pH) and response to pharmacological anti-reflux therapy were retrospectively reviewed in 38 patients with non-acid GERC and compared with those of 49 patients with acid GERC." | 3.81 | Comparison of clinical characteristics of chronic cough due to non-acid and acid gastroesophageal reflux. ( Chen, Q; Liang, S; Lü, H; Qiu, Z; Xu, X; Yang, Z; Yu, L, 2015) |
| "To evaluate the efficacy and safety of baclofen for treatment of refractory gastroesophageal reflux-induced chronic cough (GERC) unresponsive to standard anti-reflux therapy." | 3.79 | Therapeutic efficacy of baclofen in refractory gastroesophageal reflux-induced chronic cough. ( Chen, Q; Liang, SW; Lv, HJ; Qiu, ZM; Xu, XH; Yang, ZM; Yu, L, 2013) |
| "In a complex seven-period cross-over trial to study the effects of a drug in attenuating capsaicin-induced coughing, counts of numbers of coughs were recorded 32 times in each period." | 3.71 | Dynamic modelling of a challenge-escalation cross-over study of treatment of capsaicin-induced coughing. ( Jackson, D; Jones, B; Lindsey, JK; Stevens, JW, 2002) |
| " Secondary end-points were the rate of control of chronic cough at each step of therapy, the duration of treatment required, changes in cough symptom score, health-related quality of life and possible adverse effects." | 2.75 | Efficacy and safety of modified sequential three-step empirical therapy for chronic cough. ( Li, X; Liang, S; Liu, B; Lü, H; Qiu, Z; Wang, L; Wang, Y; Wei, W; Yu, L, 2010) |
| "For diagnosis of gastroesophageal reflux, amongst other investigations, esophageal gammagraphy of swallowing, that detects alterations in the mobility of the oesophagus, secondary to a possible oesophagitis." | 2.67 | [Nocturnal spasmodic cough in the infant. Evolution after antireflux treatment]. ( Baltazar, MA; Botoy, J; Dordal, MT; Marques, L; Roca, I; Server, MT, 1994) |
| "The association between GERD and these supraesophageal symptoms may be elusive." | 1.30 | Supraesophageal manifestations of gastroesophageal reflux disease. ( Al-Sabbagh, G; Wo, JM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, XH | 1 |
| Yang, ZM | 1 |
| Chen, Q | 2 |
| Yu, L | 3 |
| Liang, SW | 1 |
| Lv, HJ | 1 |
| Qiu, ZM | 1 |
| Xu, X | 1 |
| Yang, Z | 1 |
| Liang, S | 2 |
| Lü, H | 2 |
| Qiu, Z | 3 |
| Wei, W | 1 |
| Wang, Y | 1 |
| Li, X | 1 |
| Wang, L | 1 |
| Liu, B | 1 |
| Lindsey, JK | 1 |
| Stevens, JW | 1 |
| Jones, B | 1 |
| Jackson, D | 1 |
| Dordal, MT | 1 |
| Baltazar, MA | 1 |
| Roca, I | 1 |
| Marques, L | 1 |
| Server, MT | 1 |
| Botoy, J | 1 |
| Al-Sabbagh, G | 1 |
| Wo, JM | 1 |
| Dupont, C | 1 |
| Molkhou, P | 1 |
| Petrovic, N | 1 |
| Fraitag, B | 1 |
2 trials available for domperidone and Cough
| Article | Year |
|---|---|
Efficacy and safety of modified sequential three-step empirical therapy for chronic cough.
Topics: Adult; Aminophylline; Antitussive Agents; Budesonide; Cetirizine; Chlorpheniramine; Chronic Disease; | 2010 |
[Nocturnal spasmodic cough in the infant. Evolution after antireflux treatment].
Topics: Adolescent; Child; Child, Preschool; Cisapride; Cough; Domperidone; Female; Gastroesophageal Reflux; | 1994 |
5 other studies available for domperidone and Cough
| Article | Year |
|---|---|
Therapeutic efficacy of baclofen in refractory gastroesophageal reflux-induced chronic cough.
Topics: Adult; Baclofen; Capsaicin; Cohort Studies; Cough; Domperidone; Esophageal pH Monitoring; Female; Ga | 2013 |
Comparison of clinical characteristics of chronic cough due to non-acid and acid gastroesophageal reflux.
Topics: Adult; Anti-Ulcer Agents; Baclofen; Capsaicin; Chronic Disease; Cough; Domperidone; Esophageal pH Mo | 2015 |
Dynamic modelling of a challenge-escalation cross-over study of treatment of capsaicin-induced coughing.
Topics: Adrenergic beta-Agonists; Albuterol; Capsaicin; Cough; Cross-Over Studies; Domperidone; Dopamine Ant | 2002 |
Supraesophageal manifestations of gastroesophageal reflux disease.
Topics: Adult; Anti-Ulcer Agents; Cough; Domperidone; Dopamine Antagonists; Endoscopy, Gastrointestinal; Fem | 1999 |
[Treatment using Motilium of gastro-esophageal reflux associated with respiratory manifestations in children].
Topics: Asthma; Bronchitis; Child; Child, Preschool; Chronic Disease; Cough; Domperidone; Gastroesophageal R | 1989 |