diclofenac has been researched along with Ulcer in 46 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We describe a woman case who took diclofenac for many years and developed both ileal ulceration and diaphragm-like colonic structure." | 8.80 | [An ileal ulcer and diaphragm-type colonic stenosis due to diclofenac]. ( Aguirre Palacio, A; Grilo Reina, A; Rafel Ribas, E; Romero Gómez, M, 1999) |
| " Published data indicate that diclofenac 75 to 150mg daily (25 to 50mg 3 times daily) is comparable in efficacy with ordinary aspirin 3 to 5g daily and indomethacin 75 to 150mg daily in rheumatoid arthritis and with indomethacin in osteoarthritis." | 8.76 | Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin. ( Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM, 1980) |
| " Our pharmacokinetic studies of 7e demonstrated this prodrug is a potential candidate for a slower and sustained release form of rhein." | 5.38 | Bone-targeting glycol and NSAIDS ester prodrugs of rhein: synthesis, hydroxyapatite affinity, stability, anti-inflammatory, ulcerogenicity index and pharmacokinetics studies. ( Cai, J; Chao, M; Chen, J; Duan, Y; Ji, M; Yu, J, 2012) |
| " In contrast, the small intestines in old rats of both genders given the 50 mg/kg dosage had >30% fewer ulcers and a fourfold decrease in area of ulceration compared to young rats." | 5.31 | Aging enhances susceptibility of diclofenac-treated rats to gastric ulceration, while attenuating enteropathy. ( Atchison, CR; Balakumaran, A; Hoffmann, WE; Treinen-Moslen, M; West, AB, 2000) |
| "Diclofenac sodium is a widely used enteric-coated nonsteroidal anti-inflammatory drug." | 5.28 | 'Diaphragmlike' stricture and ulcer of the colon during diclofenac treatment. ( Becich, MJ; Evans, BA; Martin, SP; Trellis, DR; Whitcomb, DC, 1992) |
| " We describe a woman case who took diclofenac for many years and developed both ileal ulceration and diaphragm-like colonic structure." | 4.80 | [An ileal ulcer and diaphragm-type colonic stenosis due to diclofenac]. ( Aguirre Palacio, A; Grilo Reina, A; Rafel Ribas, E; Romero Gómez, M, 1999) |
| " Published data indicate that diclofenac 75 to 150mg daily (25 to 50mg 3 times daily) is comparable in efficacy with ordinary aspirin 3 to 5g daily and indomethacin 75 to 150mg daily in rheumatoid arthritis and with indomethacin in osteoarthritis." | 4.76 | Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin. ( Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM, 1980) |
| " Amongst all the synthesized derivatives, compound 56 showed the significant anti-inflammatory activity in both rat paw edema models with very less ulcerogenic liability in comparison to standard diclofenac, celecoxib, and zileuton." | 3.85 | Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity. ( Bandresh, R; Shrivastava, SK; Srivastava, P; Tripathi, A; Tripathi, PN, 2017) |
| " Ulcerated lesions in intestinal mucosa were observed and breaking strength decreased in all diclofenac sodium treated rats." | 3.78 | Diclofenac sodium and Imipenem action on rat intestinal mucosa: a biomechanical and histological study. ( Gonçalves Junior, I; Kobayasi, S; Naresse, LE; Rodrigues, MA, 2012) |
| "Small intestinal ulceration is a frequent and potentially serious condition associated with nonselective cyclooxygenase 1/2 inhibitors (nonsteroidal anti-inflammatory drugs, NSAIDs) including diclofenac (DCF)." | 3.76 | Pharmacologic targeting or genetic deletion of mitochondrial cyclophilin D protects from NSAID-induced small intestinal ulceration in mice. ( Boelsterli, UA; Gavillet, B; LoGuidice, A; Proli, A; Ramirez-Alcantara, V, 2010) |
| "Small intestinal ulceration, bleeding, and inflammation are major adverse effects associated with the use of diclofenac (DCF) or other nonsteroidal anti-inflammatory drugs (NSAIDs)." | 3.75 | Protection from diclofenac-induced small intestinal injury by the JNK inhibitor SP600125 in a mouse model of NSAID-associated enteropathy. ( Boelsterli, UA; LoGuidice, A; Ramirez-Alcantara, V, 2009) |
| " Inhibition of prostaglandin synthesis by traditional NSAIDs such as indomethacin and diclofenac which non-selectively inhibit both PGHS-1 and PGHS-2, causes gastric and intestinal ulceration and delays gastric ulcer healing in chronic models." | 3.70 | Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats. ( Flogerzi, B; Halter, F; Netzer, P; Peskar, BM; Schmassmann, A; Stettler, C; Stroff, T, 1998) |
| "Rats were treated orally with diclofenac (10-100 mg/kg) and killed after 1-24 hours, and their gastrointestinal (GI) tracts were evaluated for ulcer number and area." | 3.70 | Drug enterocyte adducts: possible causal factor for diclofenac enteropathy in rats. ( Aronson, JF; Atchison, CR; Balakumaran, A; Daiker, DH; Hargus, SJ; Hoffmann, WE; Pohl, LR; Shipp, BK; Treinen-Moslen, M; West, AB, 2000) |
| " Our pharmacokinetic studies of 7e demonstrated this prodrug is a potential candidate for a slower and sustained release form of rhein." | 1.38 | Bone-targeting glycol and NSAIDS ester prodrugs of rhein: synthesis, hydroxyapatite affinity, stability, anti-inflammatory, ulcerogenicity index and pharmacokinetics studies. ( Cai, J; Chao, M; Chen, J; Duan, Y; Ji, M; Yu, J, 2012) |
| " In contrast, the small intestines in old rats of both genders given the 50 mg/kg dosage had >30% fewer ulcers and a fourfold decrease in area of ulceration compared to young rats." | 1.31 | Aging enhances susceptibility of diclofenac-treated rats to gastric ulceration, while attenuating enteropathy. ( Atchison, CR; Balakumaran, A; Hoffmann, WE; Treinen-Moslen, M; West, AB, 2000) |
| "Diclofenac slow release was the most commonly involved drug." | 1.31 | Clinical, endoscopic, and histologic spectrum of nonsteroidal anti-inflammatory drug-induced lesions in the colon. ( Kiener, HP; Oberhuber, G; Püspök, A, 2000) |
| "A report is presented of five aged patients with hemorrhagic colon ulcer, which was strongly suspected to be a side effect of non steroidal anti-inflammatory drugs (NSAID)." | 1.30 | [Hemorrhagic colon ulcer as a side effect of non-steroidal anti-inflammatory drugs in five aged patients]. ( Kusakabe, N; Matsui, I; Matsui, Y; Matsumura, Y; Morimoto, S; Ogihara, T; Takahashi, E, 1997) |
| "Diclofenac sodium is a widely used enteric-coated nonsteroidal anti-inflammatory drug." | 1.28 | 'Diaphragmlike' stricture and ulcer of the colon during diclofenac treatment. ( Becich, MJ; Evans, BA; Martin, SP; Trellis, DR; Whitcomb, DC, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.17) | 18.7374 |
| 1990's | 12 (26.09) | 18.2507 |
| 2000's | 16 (34.78) | 29.6817 |
| 2010's | 15 (32.61) | 24.3611 |
| 2020's | 2 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Husain, A | 1 |
| Ahmad, A | 1 |
| Alam, MM | 1 |
| Ajmal, M | 1 |
| Ahuja, P | 1 |
| Bhandari, SV | 1 |
| Dangre, SC | 1 |
| Bothara, KG | 1 |
| Patil, AA | 1 |
| Sarkate, AP | 1 |
| Lokwani, DK | 1 |
| Gore, ST | 1 |
| Deshmane, BJ | 1 |
| Raparti, VT | 1 |
| Khachane, CV | 1 |
| Cai, J | 1 |
| Duan, Y | 1 |
| Yu, J | 1 |
| Chen, J | 1 |
| Chao, M | 1 |
| Ji, M | 1 |
| Elshemy, HAH | 1 |
| Abdelall, EKA | 1 |
| Azouz, AA | 1 |
| Moawad, A | 1 |
| Ali, WAM | 1 |
| Safwat, NM | 1 |
| Shrivastava, SK | 1 |
| Srivastava, P | 1 |
| Bandresh, R | 1 |
| Tripathi, PN | 1 |
| Tripathi, A | 1 |
| Kamboj, AK | 1 |
| Moreira, RK | 1 |
| Sweetser, S | 1 |
| Xu, N | 1 |
| Zhang, C | 1 |
| Jing, L | 1 |
| Mou, S | 1 |
| Cao, X | 1 |
| Yu, Z | 1 |
| Ahmad, H | 1 |
| Verma, S | 1 |
| Kumar, VL | 1 |
| Bronswijk, M | 1 |
| Christiaens, P | 1 |
| Van Olmen, A | 1 |
| Küttner Magalhães, R | 1 |
| Ferreira, JM | 1 |
| Pedroto, I | 1 |
| Goswami, SK | 1 |
| Wan, D | 1 |
| Yang, J | 1 |
| Trindade da Silva, CA | 1 |
| Morisseau, C | 1 |
| Kodani, SD | 1 |
| Yang, GY | 1 |
| Inceoglu, B | 1 |
| Hammock, BD | 1 |
| Scarpignato, C | 1 |
| Dolak, W | 1 |
| Lanas, A | 1 |
| Matzneller, P | 1 |
| Renzulli, C | 1 |
| Grimaldi, M | 1 |
| Zeitlinger, M | 1 |
| Bjarnason, I | 2 |
| Schmidtko, J | 1 |
| Truninger, K | 1 |
| Gugger, M | 1 |
| Cottagnoud, P | 1 |
| Stucki, A | 1 |
| Björnsson, E | 1 |
| Westgaard, G | 1 |
| Egea Valenzuela, J | 1 |
| Sánchez Torres, A | 1 |
| Alajarín Cervera, M | 1 |
| Gil Martínez, J | 1 |
| Carballo Alvarez, F | 1 |
| de Carvalho, PS | 1 |
| Maróstica, M | 1 |
| Gambero, A | 1 |
| Pedrazzoli, J | 1 |
| Fujimori, S | 1 |
| Gudis, K | 1 |
| Takahashi, Y | 1 |
| Seo, T | 1 |
| Yamada, Y | 1 |
| Ehara, A | 1 |
| Kobayashi, T | 1 |
| Mitsui, K | 1 |
| Yonezawa, M | 1 |
| Tanaka, S | 1 |
| Tatsuguchi, A | 1 |
| Sakamoto, C | 1 |
| Ramirez-Alcantara, V | 2 |
| LoGuidice, A | 3 |
| Boelsterli, UA | 3 |
| Shetty, SR | 1 |
| Chatra, L | 1 |
| Shenai, P | 1 |
| Rao, PK | 1 |
| Proli, A | 1 |
| Gavillet, B | 1 |
| Wallace, BD | 1 |
| Bendel, L | 1 |
| Redinbo, MR | 1 |
| Gonçalves Junior, I | 1 |
| Naresse, LE | 1 |
| Rodrigues, MA | 1 |
| Kobayasi, S | 1 |
| Zhu, Y | 1 |
| Zhang, QY | 1 |
| Hawkey, CJ | 2 |
| Ell, C | 1 |
| Simon, B | 1 |
| Albert, J | 1 |
| Keuchel, M | 1 |
| McAlindon, M | 1 |
| Fortun, P | 1 |
| Schumann, S | 1 |
| Bolten, W | 1 |
| Shonde, A | 1 |
| Hugot, JL | 1 |
| Yu, V | 1 |
| Arulmani, U | 1 |
| Krammer, G | 1 |
| Rebuli, R | 1 |
| Toth, E | 1 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Pakes, GE | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| D'Alteroche, L | 1 |
| Bourlier, P | 1 |
| Barre, I | 1 |
| Metman, EH | 1 |
| Bielecki, JW | 1 |
| Gebbers, JO | 1 |
| Filippini, L | 1 |
| Healy, CM | 1 |
| Thornhill, MH | 1 |
| Halter, F | 2 |
| Ruchti, C | 1 |
| Keating, JP | 1 |
| McIlwaine, J | 1 |
| Hudson, N | 1 |
| Wilkinson, MJ | 1 |
| Swannell, AJ | 1 |
| Steele, RJ | 1 |
| Kirsch, M | 1 |
| Matsui, Y | 1 |
| Matsui, I | 1 |
| Kusakabe, N | 1 |
| Matsumura, Y | 1 |
| Takahashi, E | 1 |
| Morimoto, S | 1 |
| Ogihara, T | 1 |
| Schmassmann, A | 1 |
| Peskar, BM | 1 |
| Stettler, C | 1 |
| Netzer, P | 1 |
| Stroff, T | 1 |
| Flogerzi, B | 1 |
| Aguirre Palacio, A | 1 |
| Romero Gómez, M | 1 |
| Grilo Reina, A | 1 |
| Rafel Ribas, E | 1 |
| Atchison, CR | 2 |
| Balakumaran, A | 2 |
| West, AB | 2 |
| Hoffmann, WE | 2 |
| Treinen-Moslen, M | 2 |
| Püspök, A | 1 |
| Kiener, HP | 1 |
| Oberhuber, G | 1 |
| Kehrer, G | 1 |
| Bosseckert, H | 1 |
| Koppe, P | 1 |
| Lutz, B | 1 |
| Will, U | 1 |
| Zinsser, E | 1 |
| Hargus, SJ | 1 |
| Pohl, LR | 1 |
| Daiker, DH | 1 |
| Aronson, JF | 1 |
| Shipp, BK | 1 |
| Isler, M | 1 |
| Bahceci, M | 1 |
| Anthony, A | 1 |
| Somasundaram, S | 1 |
| Yamaura, T | 1 |
| Tsugane, E | 1 |
| Sakaguchi, M | 1 |
| Rokuhara, A | 1 |
| Kiyosawa, K | 1 |
| Akamatsu, T | 1 |
| Benoit, R | 1 |
| Grobost, O | 1 |
| Crepeau, T | 1 |
| Whitcomb, DC | 1 |
| Martin, SP | 1 |
| Trellis, DR | 1 |
| Evans, BA | 1 |
| Becich, MJ | 1 |
| Carson, J | 1 |
| Notis, WM | 1 |
| Orris, ES | 1 |
4 reviews available for diclofenac and Ulcer
| Article | Year |
|---|---|
Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin.
Topics: Adult; Animals; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Interact | 1980 |
[An ileal ulcer and diaphragm-type colonic stenosis due to diclofenac].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Colon; Constriction, Pathologic; Diclofena | 1999 |
[A case of multiple colonic ulcerations and megacolon associated with nonsteroidal antiinflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Diclofenac; Female; Humans; Megacolon; Mi | 2001 |
[Diaphragm-like strictures of the colon from diclofenac].
Topics: Abdominal Pain; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; | 2001 |
2 trials available for diclofenac and Ulcer
| Article | Year |
|---|---|
Rifaximin Reduces the Number and Severity of Intestinal Lesions Associated With Use of Nonsteroidal Anti-Inflammatory Drugs in Humans.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Delayed-Ac | 2017 |
Less small-bowel injury with lumiracoxib compared with naproxen plus omeprazole.
Topics: Administration, Oral; Adult; Aged; Capsule Endoscopes; Cross-Over Studies; Cyclooxygenase Inhibitors | 2008 |
40 other studies available for diclofenac and Ulcer
| Article | Year |
|---|---|
Fenbufen based 3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-ones as safer antiinflammatory and analgesic agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Female; Lipid Peroxidation | 2009 |
Design, synthesis and pharmacological screening of novel nitric oxide donors containing 1,5-diarylpyrazolin-3-one as nontoxic NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Edema; Female; Male; Mice; Model | 2009 |
Bone-targeting glycol and NSAIDS ester prodrugs of rhein: synthesis, hydroxyapatite affinity, stability, anti-inflammatory, ulcerogenicity index and pharmacokinetics studies.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Chemistry Techniqu | 2012 |
Synthesis, anti-inflammatory, cyclooxygenases inhibitions assays and histopathological study of poly-substituted 1,3,5-triazines: Confirmation of regiospecific pyrazole cyclization by HMBC.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Synthetic; Cyclization; Cycl | 2017 |
Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Cyclooxygenase Inhi | 2017 |
NSAID-Induced Colopathy.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Colonoscopy; Diclofenac; Humans; Ma | 2021 |
Protective effect and mechanism of rebamipide on NSAIDs associated small bowel injury.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Claudin-1; Cytokines; Diclofenac; Disease | 2021 |
Effect of roxithromycin on mucosal damage, oxidative stress and pro-inflammatory markers in experimental model of colitis.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Diclofenac; Edema; | 2018 |
Circumferential Ulcerations in the Ascending Colon.
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colon; Colonic Diseases; Colonoscopy; Di | 2019 |
Nonsteroidal anti-inflammatory drug (NSAID)-induced colopathy with diaphragm-like strictures.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Colonoscopy; Diclofenac; Female; Hu | 2014 |
Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytoprotection; Diclofenac; Enzyme Inhibitors; Epo | 2016 |
[What is your diagnosis? Diaphragma disease].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Diseases; Diagnosis, Differential; Diclofe | 2008 |
Severe injury to the small bowel associated with a short course of diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Intestinal Diseases; Intestine, | 2008 |
[A rectal ulcer perforated into the presacral space].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Hematoma; Humans; Intestinal Perforatio | 2008 |
Synthesis and pharmacological characterization of a novel nitric oxide-releasing diclofenac derivative containing a benzofuroxan moiety.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Carrageenan; Cyclooxygenase 2; Diclo | 2010 |
Distribution of small intestinal mucosal injuries as a result of NSAID administration.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Diclofenac; Humans; Intestinal Di | 2010 |
Protection from diclofenac-induced small intestinal injury by the JNK inhibitor SP600125 in a mouse model of NSAID-associated enteropathy.
Topics: Alkaline Phosphatase; Animals; Anthracenes; Apoptosis; Blood Proteins; Diclofenac; Intestinal Diseas | 2009 |
Stevens-Johnson syndrome: a case report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Conjunctival Diseases; Dental Caries; Diclofenac; Female; F | 2010 |
Pharmacologic targeting or genetic deletion of mitochondrial cyclophilin D protects from NSAID-induced small intestinal ulceration in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclophilins; Cyclospori | 2010 |
Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Enterocytes; Escherichia coli; Escheri | 2012 |
Diclofenac sodium and Imipenem action on rat intestinal mucosa: a biomechanical and histological study.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Imipenem; Intes | 2012 |
Role of intestinal cytochrome p450 enzymes in diclofenac-induced toxicity in the small intestine.
Topics: Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Citrus paradisi; Cytochro | 2012 |
[Are right colonic lesions specific to sustained-release NSAID preparations?].
Topics: Aged; Arthritis, Rheumatoid; Cecal Diseases; Colonic Diseases; Delayed-Action Preparations; Diclofen | 1994 |
[Segmental small intestine lesions after taking non-steroidal antirheumatic drugs].
Topics: Abdominal Pain; Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Diclofenac; H | 1995 |
An association between recurrent oro-genital ulceration and non-steroidal anti-inflammatory drugs.
Topics: Diclofenac; Drug Hypersensitivity; Female; Flurbiprofen; Genital Diseases, Female; Humans; Middle Ag | 1995 |
Ileo-caecal ulceration associated with the use of diclofenac slow release.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cecal Diseases; Delayed-Action Preparations; Diclofenac; Hu | 1994 |
Simultaneous small and large bowel ulceration associated with short term NSAID use.
Topics: Aged; Aged, 80 and over; Colonic Diseases; Diclofenac; Humans; Ileal Diseases; Intestinal Perforatio | 1993 |
Ileo-caecal ulceration associated with the use of diclofenac slow release.
Topics: Adult; Delayed-Action Preparations; Diclofenac; Humans; Intestinal Diseases; Joint Diseases; Male; U | 1993 |
Nonsteroidal antiinflammatory drug colopathy: mimicry of Crohn's disease and colon carcinoma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Colonic Neoplasms; Crohn Disease; Diagnos | 1997 |
[Hemorrhagic colon ulcer as a side effect of non-steroidal anti-inflammatory drugs in five aged patients].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Diabetes Complications; Diclofenac; | 1997 |
Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inhibitors; Dicl | 1998 |
Aging enhances susceptibility of diclofenac-treated rats to gastric ulceration, while attenuating enteropathy.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Diclofenac; Female; | 2000 |
Clinical, endoscopic, and histologic spectrum of nonsteroidal anti-inflammatory drug-induced lesions in the colon.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colonoscopy; Delay | 2000 |
Unusual negative side effects of non-steroidal anti-inflammatory drugs in the proximal colon.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Diseases; Diagnos | 2000 |
Drug enterocyte adducts: possible causal factor for diclofenac enteropathy in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Diclofenac; Dose-Response Relationship, Drug | 2000 |
Cataflam-induced esophageal ulceration.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Esophageal Diseases; Female; Humans; Ulc | 2001 |
Why the mesenteric margin?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Intestinal Diseases; Mesenteric Arterie | 2001 |
Pathogenesis of diclofenac enteropathy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Intestinal Diseases; Ulcer | 2001 |
'Diaphragmlike' stricture and ulcer of the colon during diclofenac treatment.
Topics: Anemia, Hypochromic; Biopsy; Colon; Colonic Diseases; Constriction, Pathologic; Delayed-Action Prepa | 1992 |
Colonic ulceration and bleeding during diclofenac therapy.
Topics: Aged; Colonic Diseases; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Middle Aged; Tablet | 1990 |