cp 96345 and Pain
cp 96345 has been researched along with Pain in 24 studies
Research
Studies (24)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (79.17) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Liu, L; Pasricha, PJ; Shenoy, M | 1 |
| Boudah, A; Jasmin, L; Ohara, PT | 1 |
| Cahill, CM; Henry, JL; Landau, AM; Ribeiro-da-Silva, A; St Louis, M; Yashpal, K | 1 |
| Garces, YI; Minshall, RD; Rabito, SF; Sagen, J | 1 |
| Coderre, TJ; Henry, JL; Radhakrishnan, V; Yashpal, K | 1 |
| Katsumata, K; Kisara, K; Sakurada, S; Sakurada, T; Tan-No, K; Yogo, H | 1 |
| Henry, JL | 1 |
| Bordner, J; Bryce, DK; Drozda, SE; Jackson, ER; Longo, KP; Lowe, JA; McLean, S; Morrone, J; Snider, RM; Zorn, SH | 1 |
| Boucher, S; Couture, R; Picard, P; Regoli, D | 1 |
| Asai, R; Kanai, Y; Murase, A; Nagahisa, A; Nakagaki, T; Shieh, TC; Taniguchi, K; Tsuchiya-Nakagaki, M | 2 |
| Nagy, J; Pethö, G; Szolcsányi, J | 1 |
| Mizuguchi, T; Shimoyama, N; Yamamoto, T | 1 |
| Jett, MF; Michelson, S | 1 |
| Traub, RJ | 1 |
| Goto, F; Hasegawa, M; Ishizaki, K; Karasawa, S; Takahashi, K | 1 |
| Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J | 1 |
| Goto, F; Ishizaki, K; Karasawa, S; Nara, T; Obata, H; Sasaki, M | 1 |
| Ando, R; Kawamura, S; Sakurada, T; Watanabe, C; Yonezawa, A | 1 |
| Willis, WD | 1 |
| Birch, PJ; Harrison, SM; Hayes, AG; Rogers, H; Tyers, MB | 1 |
| Yaksh, TL; Yamamoto, T | 1 |
| De Koninck, Y; Henry, JL | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
Reviews
3 review(s) available for cp 96345 and Pain
| Article | Year |
|---|---|
Participation of substance P in spinal physiological responses to peripheral aversive stimulation.
Topics: Animals; Biphenyl Compounds; Hypnotics and Sedatives; Neurokinin A; Neurons; Pain; Receptors, Neurokinin-2; Reflex; Spinal Cord; Substance P | 1993 |
Discovery of CP-96,345 and its characterization in disease models involving substance P.
Topics: Analgesics; Animals; Asthma; Binding, Competitive; Biphenyl Compounds; Disease Models, Animal; Inflammation; Pain; Receptors, Neurokinin-2; Substance P | 1993 |
Role of neurotransmitters in sensitization of pain responses.
Topics: Animals; Biphenyl Compounds; Capsaicin; Excitatory Amino Acid Agonists; Haplorhini; Hot Temperature; Humans; Hyperalgesia; Injections, Intradermal; Long-Term Potentiation; Mechanoreceptors; Microdialysis; Models, Animal; Models, Neurological; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Pain; Phosphorylation; Posterior Horn Cells; Protein Processing, Post-Translational; Rats; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Signal Transduction; Spinothalamic Tracts; Substance P | 2001 |
Other Studies
21 other study(ies) available for cp 96345 and Pain
| Article | Year |
|---|---|
Substance P and calcitonin gene related peptide mediate pain in chronic pancreatitis and their expression is driven by nerve growth factor.
Topics: Animals; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Drug Evaluation, Preclinical; Gene Expression Regulation; Injections, Spinal; Male; Nerve Growth Factor; Nociceptive Pain; Pain; Pain Measurement; Pancreatitis, Chronic; Peptide Fragments; Rats; Rats, Sprague-Dawley; Substance P | 2011 |
Long-term effects of decreased noradrenergic central nervous system innervation on pain behavior and opioid antinociception.
Topics: Analgesics, Opioid; Animals; Antibodies, Monoclonal; Behavior, Animal; Biphenyl Compounds; Central Nervous System; Denervation; Disease Models, Animal; Disease Progression; Female; Hyperalgesia; Immunohistochemistry; Immunotoxins; Injections, Intraventricular; Injections, Spinal; Lumbosacral Region; Male; Morphine; Norepinephrine; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord; Substance P; Time | 2003 |
Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Colitis; Colon; Disease Models, Animal; Enteric Nervous System; Ethanol; Inflammation Mediators; Male; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Oligonucleotides, Antisense; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Sympathetic Nervous System; Zymosan | 2007 |
Lack of potent antinociceptive activity by substance P antagonist CP-96,345 in the rat spinal cord.
Topics: Analgesics; Analysis of Variance; Animals; Binding, Competitive; Biphenyl Compounds; In Vitro Techniques; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Spinal Cord; Substance P | 1993 |
CP-96,345, but not its stereoisomer, CP-96,344, blocks the nociceptive responses to intrathecally administered substance P and to noxious thermal and chemical stimuli in the rat.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Formaldehyde; Heart Rate; Hot Temperature; Injections, Spinal; Male; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Spinal Cord; Stereoisomerism; Substance P | 1993 |
Antinociception induced by CP 96,345, a non-peptide NK-1 receptor antagonist, in the mouse formalin and capsaicin tests.
Topics: Analgesics; Animals; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Formaldehyde; Hypnotics and Sedatives; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Naloxone; Pain; Pain Measurement; Postural Balance; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1993 |
Receptor characterization of the spinal action of neurokinins on nociception: a three receptor hypothesis.
Topics: Animals; Benzamides; Biphenyl Compounds; Models, Neurological; Neurokinin A; Neurokinin-1 Receptor Antagonists; Oligopeptides; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Spinal Cord; Substance P | 1993 |
Non-specific activity of (+/-)CP-96,345 in models of pain and inflammation.
Topics: Animals; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Hypnotics and Sedatives; Inflammation; Neurokinin-1 Receptor Antagonists; Pain; Rats; Stereoisomerism; Substance P; Time Factors; Verapamil | 1993 |
Effect of CP-96,345 a non-peptide substance P antagonist, capsaicin, resiniferatoxin and ruthenium red on nociception.
Topics: Action Potentials; Analgesics; Animals; Biphenyl Compounds; Capsaicin; Diterpenes; Hot Temperature; Injections, Spinal; Pain; Peripheral Nerves; Rats; Ruthenium Red; Spinal Cord; Spinal Nerve Roots; Stereoisomerism; Substance P | 1993 |
Effects of intrathecal FK888, a novel dipeptide NK1 receptor antagonist, on the formalin test in the rat.
Topics: Animals; Behavior, Animal; Biphenyl Compounds; Dipeptides; Escape Reaction; Formaldehyde; Indoles; Injections, Spinal; Male; Movement; Nociceptors; Pain; Rats; Rats, Sprague-Dawley | 1993 |
The formalin test in rat: validation of an automated system.
Topics: Animals; Behavior, Animal; Biphenyl Compounds; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Foot; Formaldehyde; Male; Morphine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Signal Processing, Computer-Assisted; Stimulation, Chemical | 1996 |
The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Foot; Formaldehyde; Hot Temperature; Hyperalgesia; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1996 |
Intrathecal neurokinin-1 receptor antagonist reduces isoflurane MAC in rats.
Topics: Anesthetics, Inhalation; Animals; Biphenyl Compounds; Excitatory Amino Acid Antagonists; Isoflurane; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Pain; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Effect of tachykinin receptor antagonists in experimental neuropathic pain.
Topics: Analgesics; Animals; Benzamides; Biphenyl Compounds; Denervation; Diabetes Mellitus, Experimental; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Sciatic Nerve | 1998 |
Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Anesthetics, Inhalation; Animals; Biphenyl Compounds; Catheters, Indwelling; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Locomotion; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Synaptic Transmission; Valine | 1999 |
Involvement of spinal NK2 and NMDA receptors in aversive behavior induced by intra-arterial injection of capsaicin.
Topics: Animals; Avoidance Learning; Biphenyl Compounds; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Femoral Artery; Guinea Pigs; Hindlimb; Injections, Intra-Arterial; Male; Neurokinin A; Nociceptors; Pain; Peptide Fragments; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Spinal Cord; Vocalization, Animal | 2001 |
The non-peptide NK1 receptor antagonist, (+/-)-CP-96,345, produces antinociceptive and anti-oedema effects in the rat.
Topics: Analgesics; Animals; Behavior, Animal; Biphenyl Compounds; Carrageenan; Edema; Formaldehyde; Male; Pain; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter | 1992 |
Non-specific activity of (+/-)-CP-96,345 in models of pain and inflammation.
Topics: Analysis of Variance; Animals; Binding Sites; Biphenyl Compounds; Disease Models, Animal; Edema; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Stereoisomerism | 1992 |
Effects of intrathecal capsaicin and an NK-1 antagonist, CP,96-345, on the thermal hyperalgesia observed following unilateral constriction of the sciatic nerve in the rat.
Topics: Animals; Biphenyl Compounds; Capsaicin; Hot Temperature; Hypnotics and Sedatives; Injections, Spinal; Male; Neurokinin A; Neuropeptides; Nociceptors; Pain; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 1992 |
Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation.
Topics: Animals; Biphenyl Compounds; Cats; Evoked Potentials; Ganglia, Spinal; Neurons; Nociceptors; Pain; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Spinal Cord; Substance P; Synapses; Time Factors; Touch | 1991 |
Novel substance P antagonist, CP-96,345, blocks responses of cat spinal dorsal horn neurons to noxious cutaneous stimulation and to substance P.
Topics: Animals; Biphenyl Compounds; Cats; Evoked Potentials; Hot Temperature; Neurons; Pain; Skin; Spinal Cord; Substance P | 1991 |