colistin and Atrophy

colistin has been researched along with Atrophy* in 1 studies

Other Studies

1 other study(ies) available for colistin and Atrophy

ArticleYear
Competitive mechanisms of basic peptides inducing transganglionic degenerative atrophy.
    Acta morphologica Hungarica, 1988, Volume: 36, Issue:1-2

    In addition to the classical microtubule inhibitors (antimitotic agents), transganglionic degenerative atrophy of central terminals of primary sensory neurons can be induced also by means of applying to a peripheral nerve basic polypeptides (Polymyxin B and Colimycin) and two basic derivatives of glutamic acid that do not exert any microtubule inhibition. This effect is independent of other pharmacological effects (histamine liberation, Ca2+ -binding, etc.) of the applied compounds, and probably it is based on a competitive reaction with nerve growth factor.

    Topics: Animals; Atrophy; Colistin; Female; Glutamates; Histamine; Male; Nerve Degeneration; Neurons, Afferent; Peptides; Polymyxin B; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord

1988