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clonidine and Tremor

clonidine has been researched along with Tremor in 15 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"Accelerometric tremorgrams were recorded from 25 subjects affected by essential tremor and analysed by a Berg-Fourier frequency analyser before and during venous infusion of the following drugs: propranolol (beta-blocker), clonidine (alpha-presynaptic adrenergic agonist), urapidil (alpha-postsynaptic blocker), trazodone (adrenolytic agent) and placebo."9.06Propranolol, clonidine, urapidil and trazodone infusion in essential tremor: a double-blind crossover trial. ( Caccia, MR; Cataldi, G; Galimberti, V; Mangoni, A; Osio, M, 1989)
"The effects of oral administration of azepexole 10 mg, clonidine 300 micrograms and placebo on baroreceptor mediated reflex bradycardia and physiological tremor were investigated in six healthy volunteers."9.05Effects of azepexole and clonidine on baroreceptor mediated reflex bradycardia and physiological tremor in man. ( Harron, DW; Riddell, JG; Shanks, RG, 1985)
"Thirty-seven patients with essential tremor were given intramuscular clonidine injections of 0."7.69[Acute pharmacological test of clonidine in essential tremor]. ( Serrano Dueñas, M, 1997)
"The purported alpha 2-adrenergic agonist clonidine was found to inhibit rest tremor at doses of 0."7.68Effect of clonidine and atropine on rest tremor in the MPTP monkey model of parkinsonism. ( Bédard, PJ; Boucher, R; Gomez-Mancilla, B, 1991)
"Clonidine exhibited a dose-dependent protection against harmine-induced tremors in mice."7.67Modification by clonidine of harmine-induced tremors in mice: involvement of serotoninergic system. ( Garg, SK; Kulkarni, SK; Shukla, VK, 1986)
"The authors present ten cases of essential tremor, studied before and after administration of clonidine with clinical tests and electrophysiological recordings."7.67Clonidine in essential tremor: preliminary observations from an open trial. ( Caccia, MR; Mangoni, A, 1985)
"Tremor was not significantly altered by clonidine therapy."6.66Clonidine in the treatment of essential tremor. ( Cone, S; Herbster, G; Koller, W, 1986)
"Tremor was quantified 8 hr later by spectral analysis of whole body movements."5.27Modulation of p,p'-DDT-induced tremor by catecholaminergic agents. ( Herr, DW; Tilson, HA, 1987)
"Accelerometric tremorgrams were recorded from 25 subjects affected by essential tremor and analysed by a Berg-Fourier frequency analyser before and during venous infusion of the following drugs: propranolol (beta-blocker), clonidine (alpha-presynaptic adrenergic agonist), urapidil (alpha-postsynaptic blocker), trazodone (adrenolytic agent) and placebo."5.06Propranolol, clonidine, urapidil and trazodone infusion in essential tremor: a double-blind crossover trial. ( Caccia, MR; Cataldi, G; Galimberti, V; Mangoni, A; Osio, M, 1989)
"The effects of oral administration of azepexole 10 mg, clonidine 300 micrograms and placebo on baroreceptor mediated reflex bradycardia and physiological tremor were investigated in six healthy volunteers."5.05Effects of azepexole and clonidine on baroreceptor mediated reflex bradycardia and physiological tremor in man. ( Harron, DW; Riddell, JG; Shanks, RG, 1985)
"Thirty-seven patients with essential tremor were given intramuscular clonidine injections of 0."3.69[Acute pharmacological test of clonidine in essential tremor]. ( Serrano Dueñas, M, 1997)
"The purported alpha 2-adrenergic agonist clonidine was found to inhibit rest tremor at doses of 0."3.68Effect of clonidine and atropine on rest tremor in the MPTP monkey model of parkinsonism. ( Bédard, PJ; Boucher, R; Gomez-Mancilla, B, 1991)
"Clonidine exhibited a dose-dependent protection against harmine-induced tremors in mice."3.67Modification by clonidine of harmine-induced tremors in mice: involvement of serotoninergic system. ( Garg, SK; Kulkarni, SK; Shukla, VK, 1986)
"The authors present ten cases of essential tremor, studied before and after administration of clonidine with clinical tests and electrophysiological recordings."3.67Clonidine in essential tremor: preliminary observations from an open trial. ( Caccia, MR; Mangoni, A, 1985)
" Under pentobarbital anesthesia, precipitated shakes and ice water-induced wet shakes were inhibited by clonidine and norepinephrine."3.65Effects of clonidine on morphine withdrawal signs in the rat. ( Loh, HH; Tseng, LF; Wei, ET, 1975)
"Tremor was not significantly altered by clonidine therapy."2.66Clonidine in the treatment of essential tremor. ( Cone, S; Herbster, G; Koller, W, 1986)
"Tremor was quantified 8 hr later by spectral analysis of whole body movements."1.27Modulation of p,p'-DDT-induced tremor by catecholaminergic agents. ( Herr, DW; Tilson, HA, 1987)
" Observed on four drug-induced behavior categories, it was found that both clonidine and propranolol attenuated the toxic effects of relatively low dose levels of digitoxin, while at higher digitoxin dose levels only propranolol was able to reduce significantly the ED50 and the LD50."1.26Effect of age, clonidine or propranolol on behavioral toxicity induced with digitoxin in mice. ( Felleman, VH; Palfai, T, 1982)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199011 (73.33)18.7374
1990's4 (26.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Palfai, T1
Felleman, VH1
Jandó, G1
Carpi, D1
Kandel, A1
Urioste, R1
Horvath, Z1
Pierre, E1
Vadi, D1
Vadasz, C1
Buzsáki, G1
Arya, DK1
Langley, RW1
Szabadi, E1
Bradshaw, CM1
Serrano Dueñas, M1
Silvestrini, B1
Lisciani, R1
Tseng, LF1
Loh, HH1
Wei, ET1
Gomez-Mancilla, B1
Boucher, R1
Bédard, PJ1
Caccia, MR2
Osio, M1
Galimberti, V1
Cataldi, G1
Mangoni, A2
Harron, DW1
Riddell, JG1
Shanks, RG1
Koller, W1
Herbster, G1
Cone, S1
Björkqvist, SE1
Shukla, VK1
Garg, SK1
Kulkarni, SK1
Herr, DW1
Tilson, HA1
Paalzow, L1

Trials

4 trials available for clonidine and Tremor

ArticleYear
Comparison of the effects of high ambient temperature and clonidine on autonomic functions in man.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:3

    Topics: Adrenergic alpha-Agonists; Adult; Autonomic Nervous System; Body Temperature; Catecholamines; Clonid

1997
Propranolol, clonidine, urapidil and trazodone infusion in essential tremor: a double-blind crossover trial.
    Acta neurologica Scandinavica, 1989, Volume: 79, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Clonidine; Double-Blind Method; Female; Humans; Injections, Intraven

1989
Effects of azepexole and clonidine on baroreceptor mediated reflex bradycardia and physiological tremor in man.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:5

    Topics: Adrenergic alpha-Agonists; Adult; Arousal; Azepines; Blood Pressure; Clonidine; Electrocardiography;

1985
Clonidine in the treatment of essential tremor.
    Movement disorders : official journal of the Movement Disorder Society, 1986, Volume: 1, Issue:4

    Topics: Clinical Trials as Topic; Clonidine; Double-Blind Method; Humans; Male; Middle Aged; Tremor

1986

Other Studies

11 other studies available for clonidine and Tremor

ArticleYear
Effect of age, clonidine or propranolol on behavioral toxicity induced with digitoxin in mice.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:3

    Topics: Aging; Animals; Behavior, Animal; Clonidine; Digitoxin; Drug Interactions; Gait; Male; Mice; Postura

1982
Spike-and-wave epilepsy in rats: sex differences and inheritance of physiological traits.
    Neuroscience, 1995, Volume: 64, Issue:2

    Topics: Animals; Clonidine; Electroencephalography; Epilepsy, Absence; Female; Hybridization, Genetic; Male;

1995
[Acute pharmacological test of clonidine in essential tremor].
    Neurologia (Barcelona, Spain), 1997, Volume: 12, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Female; Humans; Injections, Intramuscular; Male;

1997
Experimental data suggesting an adrenergic mechanism in the production of parkinsonian symptoms.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Clonidine; Female; Fenclonine; Imipramine; Male; Mice; Mice,

1976
Effects of clonidine on morphine withdrawal signs in the rat.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Anesthesia; Animals; Body Temperature; Cerebral Ventricles; Clonidine; Escape Reaction; Exophthalmos

1975
Effect of clonidine and atropine on rest tremor in the MPTP monkey model of parkinsonism.
    Clinical neuropharmacology, 1991, Volume: 14, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Atropine; Clonidine; Disease Models, Animal;

1991
Clonidine therapy for alcohol withdrawal.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327

    Topics: Carbamazepine; Clonidine; Diarrhea; Drug Therapy, Combination; Ethanol; Humans; Hyperhidrosis; Hyper

1986
Modification by clonidine of harmine-induced tremors in mice: involvement of serotoninergic system.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 282, Issue:1

    Topics: Alkaloids; Animals; Clonidine; Cyproheptadine; Fluoxetine; Harmine; Male; Mice; Quipazine; Serotonin

1986
Modulation of p,p'-DDT-induced tremor by catecholaminergic agents.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:2

    Topics: Animals; Apomorphine; Clonidine; DDT; Dopamine; Haloperidol; Male; Norepinephrine; Phenoxybenzamine;

1987
Clonidine in essential tremor: preliminary observations from an open trial.
    Journal of neurology, 1985, Volume: 232, Issue:1

    Topics: Aged; Clonidine; Diazepam; Female; Handwriting; Humans; Levodopa; Male; Middle Aged; Piribedil; Trem

1985
Analgesia produced by clonidine in mice and rats.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:5

    Topics: Analgesia; Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Exophthalmos;

1974