Page last updated: 2024-10-25

clonidine and Tics

clonidine has been researched along with Tics in 11 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Tics: Habitual, repeated, rapid contraction of certain muscles, resulting in stereotyped individualized actions that can be voluntarily suppressed for only brief periods. They often involve the face, vocal cords, neck, and less often the extremities. Examples include repetitive throat clearing, vocalizations, sniffing, pursing the lips, and excessive blinking. Tics tend to be aggravated by emotional stress. When frequent they may interfere with speech and INTERPERSONAL RELATIONS. Conditions which feature frequent and prominent tics as a primary manifestation of disease are referred to as TIC DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, pp109-10)

Research Excerpts

ExcerptRelevanceReference
"Atomoxetine and OROS methylphenidate were successfully used concomitantly in a 10-year-old boy suffering from attention-deficit/hyperactivity disorder (ADHD) with comorbid bipolar disorder and Tourette syndrome (TS)."7.73Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome. ( Benarroch, F; Gross-Tsur, V; Jaworowski, S, 2006)
"Clonidine usually serves as a tic-suppressing agent in patients with Tourette syndrome."7.71Clonidine treatment increases tics in patients with Tourette syndrome: case report. ( Kessler, AR, 2001)
"Atomoxetine and OROS methylphenidate were successfully used concomitantly in a 10-year-old boy suffering from attention-deficit/hyperactivity disorder (ADHD) with comorbid bipolar disorder and Tourette syndrome (TS)."3.73Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome. ( Benarroch, F; Gross-Tsur, V; Jaworowski, S, 2006)
" We now report that these OCD-like mice, like humans, also exhibit comorbid TS-like behaviors, including juvenile-onset tics; increased tic number, complexity and flurries; increased tic severity in males; voluntary tic suppression; and tic responsiveness to a non-cataleptic TS+OCD drug therapy (clonidine, 0."3.71A transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder circuitry. ( Burton, FH; Nordstrom, EJ, 2002)
"Clonidine usually serves as a tic-suppressing agent in patients with Tourette syndrome."3.71Clonidine treatment increases tics in patients with Tourette syndrome: case report. ( Kessler, AR, 2001)
"In clinical practice guidelines there is no consensus about the medications that should be initially offered to children and young people with Tourette's syndrome."3.01Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis. ( Behling, E; Bloch, MH; Farhat, LC; Landeros-Weisenberger, A; Levine, JLS; Macul Ferreira de Barros, P; Wang, Z, 2023)
"Tics are repetitive and sudden purposeless movements."2.44[Diagnosis and treatment of tics]. ( Topka, H, 2007)
"This article reviews the evidence published in the English language literature concerning the pharmacological treatment of tics in patients with Tourette Syndrome."2.42Pharmacological management of tics in patients with TS. ( Sandor, P, 2003)
"Clonidine was associated with markedly higher clinical efficacy vs."1.91Efficacy of clonidine in the treatment of children with tic disorder co-morbid with attention deficit hyperactivity disorder. ( Hu, B; Huang, XH; Wang, GL; Yuan, Y; Zeng, KD; Zhang, W, 2023)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Farhat, LC2
Behling, E2
Landeros-Weisenberger, A2
Levine, JLS2
Macul Ferreira de Barros, P2
Wang, Z2
Bloch, MH2
Zeng, KD1
Wang, GL1
Yuan, Y1
Zhang, W1
Huang, XH1
Hu, B1
Naguy, A1
Roman, MW1
Pringsheim, T1
Nordstrom, EJ1
Burton, FH1
Listernick, R1
Sandor, P1
Jaworowski, S1
Benarroch, F1
Gross-Tsur, V1
Topka, H1
Kessler, AR1

Reviews

5 reviews available for clonidine and Tics

ArticleYear
Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis.
    The Lancet. Child & adolescent health, 2023, Volume: 7, Issue:2

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Antipsychotic Agents; Aripiprazole; Child; Clonidi

2023
Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis.
    The Lancet. Child & adolescent health, 2023, Volume: 7, Issue:2

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Antipsychotic Agents; Aripiprazole; Child; Clonidi

2023
Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis.
    The Lancet. Child & adolescent health, 2023, Volume: 7, Issue:2

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Antipsychotic Agents; Aripiprazole; Child; Clonidi

2023
Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis.
    The Lancet. Child & adolescent health, 2023, Volume: 7, Issue:2

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Antipsychotic Agents; Aripiprazole; Child; Clonidi

2023
Clonidine Use in Psychiatry: Panacea or Panache.
    Pharmacology, 2016, Volume: 98, Issue:1-2

    Topics: Animals; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Clonidine; Humans; Men

2016
New additions to the psychopharmacopia: extended release formulations.
    Issues in mental health nursing, 2011, Volume: 32, Issue:11

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comparative Effectiveness Re

2011
Pharmacological management of tics in patients with TS.
    Journal of psychosomatic research, 2003, Volume: 55, Issue:1

    Topics: Anti-Dyskinesia Agents; Antipsychotic Agents; Clonidine; Dopamine Antagonists; Haloperidol; Humans;

2003
[Diagnosis and treatment of tics].
    MMW Fortschritte der Medizin, 2007, May-21, Volume: 149 Suppl 2

    Topics: Adolescent; Adult; Age Factors; Antipsychotic Agents; Child; Child, Preschool; Chronic Disease; Clin

2007

Other Studies

6 other studies available for clonidine and Tics

ArticleYear
Efficacy of clonidine in the treatment of children with tic disorder co-morbid with attention deficit hyperactivity disorder.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:9

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Clonidine;

2023
Psychopharmacology for the clinician: management of comorbid Tourette syndrome and attention-deficit/hyperactivity disorder: are psychostimulants an option?
    Journal of psychiatry & neuroscience : JPN, 2012, Volume: 37, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Attention Deficit Disorder with Hyperactivity; Central Nervous

2012
A transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder circuitry.
    Molecular psychiatry, 2002, Volume: 7, Issue:6

    Topics: Analgesics; Animals; Cholera Toxin; Clonidine; Comorbidity; Female; Incidence; Male; Mice; Mice, Tra

2002
A nine-year-old girl with new-onset tics.
    Pediatric annals, 2003, Volume: 32, Issue:2

    Topics: Antipsychotic Agents; Child; Chorea; Clonidine; Diagnosis, Differential; Female; Humans; Obsessive-C

2003
Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome.
    Journal of child and adolescent psychopharmacology, 2006, Volume: 16, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivi

2006
Clonidine treatment increases tics in patients with Tourette syndrome: case report.
    Journal of child neurology, 2001, Volume: 16, Issue:5

    Topics: Adrenergic alpha-Agonists; Child; Clonidine; Humans; Male; Tics; Tourette Syndrome

2001