clonidine has been researched along with Edema in 12 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine 1 mg/kg ip given before thermal injury significantly inhibited the edema formation in mice and rats during the early stage of burn." | 7.67 | [Inhibitory effects of clonidine on edema formation after thermal injury in mice and rats]. ( Jiang, DJ; Tao, JY; Xu, SY, 1989) |
| ") exhibited anti-inflammatory activity in carrageenan-, formalin-, 5-HT- and histamine-induced paw oedema in rats." | 7.67 | Anti-inflammatory actions of clonidine, guanfacine and B-HT 920 against various inflammagen-induced acute paw oedema in rats. ( Kulkarni, SK; Kunchandy, J; Mehta, AK, 1986) |
| " α1 (phenylephrine), α2 (clonidine), β1 (dobutamine), or β2 (salbutamol)-adrenoceptor agonists were injected subcutaneously (sc), intrathecally (it), or intra-articularly (ia) to activate peripheral, spinal, or intra-articular adrenoceptors and to study their effects on articular edema formation and neutrophil migration into the synovial cavity." | 3.91 | Regulation of murine arthritis by systemic, spinal, and intra-articular adrenoceptors. ( Alves, HR; Bassi, GS; Cunha, FQ; Dutra, SGV; Kanashiro, A; Leoncio, TOL; Malvar, DDC; Schneider, AH; Ulloa, L, 2019) |
| "Intrathecal Baclofen and Clonidine may be used as alternatives to provide spinally mediated antinociception when intraspinal opioid fails due to pharmacological side effects such as persistent edema." | 3.76 | Recurrent cellulitis associated with long-term intrathecal opioid infusion therapy: a case report and review of the literature. ( Chiravuri, S; Couch, JP; Liu, H; Ruan, X; Wang, F, 2010) |
| "Clonidine 1 mg/kg ip given before thermal injury significantly inhibited the edema formation in mice and rats during the early stage of burn." | 3.67 | [Inhibitory effects of clonidine on edema formation after thermal injury in mice and rats]. ( Jiang, DJ; Tao, JY; Xu, SY, 1989) |
| ") exhibited anti-inflammatory activity in carrageenan-, formalin-, 5-HT- and histamine-induced paw oedema in rats." | 3.67 | Anti-inflammatory actions of clonidine, guanfacine and B-HT 920 against various inflammagen-induced acute paw oedema in rats. ( Kulkarni, SK; Kunchandy, J; Mehta, AK, 1986) |
| " Muzolimine benefited hypertension in patients with expansion of the extracellular space and it also strengthened the effect of clonidine or minoxidil." | 3.67 | Muzolimine in advanced chronic renal failure. ( Alfonso, L; Aprile, M; Corlianò, C; De Blasi, V; Mastrangelo, F; Montinaro, AM; Napoli, M; Rizzelli, S, 1985) |
| "Clonidine-induced catalepsy in mice was used to evaluate the indirect antihistamine effect of Xylopia aethiopica, XAE." | 1.39 | Aqueous ethanol extract of the fruit of Xylopia aethiopica (Annonaceae) exhibits anti-anaphylactic and anti-inflammatory actions in mice. ( Obiri, DD; Osafo, N, 2013) |
| " The slopes of the individual dose-response curves were not significantly different which suggested a common mechanism of action." | 1.27 | Central and peripheral anti-inflammatory actions by clonidine and a structurally related imidazoline analog. ( Holsapple, MP; Lowy, MT; Malave, A; Yim, GK, 1984) |
| "aspirin were additive." | 1.27 | Therapeutic and adjunctive applications of an imidazoline anti-inflammatory agent. ( Holsapple, MP; Nichols, DE; Trizzino, J; Yim, GK, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanashiro, A | 1 |
| Leoncio, TOL | 1 |
| Schneider, AH | 1 |
| Alves, HR | 1 |
| Bassi, GS | 1 |
| Dutra, SGV | 1 |
| Cunha, FQ | 1 |
| Ulloa, L | 1 |
| Malvar, DDC | 1 |
| Obiri, DD | 1 |
| Osafo, N | 1 |
| Gyires, K | 1 |
| Zádori, ZS | 1 |
| Shujaa, N | 1 |
| Al-Khrasani, M | 1 |
| Pap, B | 1 |
| Mózes, MM | 1 |
| Mátyus, P | 1 |
| Ruan, X | 1 |
| Liu, H | 1 |
| Couch, JP | 1 |
| Wang, F | 1 |
| Chiravuri, S | 1 |
| Ghannoum, JE | 1 |
| Odingo, NA | 1 |
| Provost, N | 1 |
| Kirmeier, R | 1 |
| Truschnegg, A | 1 |
| Payer, M | 1 |
| Acham, S | 1 |
| Schulz, K | 1 |
| Jakse, N | 1 |
| Holsapple, MP | 2 |
| Malave, A | 1 |
| Lowy, MT | 1 |
| Yim, GK | 2 |
| Trizzino, J | 1 |
| Nichols, DE | 1 |
| Bietti, GB | 1 |
| De Caro, G | 1 |
| Giraldi, JP | 1 |
| Romani, E | 1 |
| Jiang, DJ | 1 |
| Tao, JY | 1 |
| Xu, SY | 1 |
| Kulkarni, SK | 1 |
| Mehta, AK | 1 |
| Kunchandy, J | 1 |
| Mastrangelo, F | 1 |
| Rizzelli, S | 1 |
| Corlianò, C | 1 |
| Alfonso, L | 1 |
| De Blasi, V | 1 |
| Aprile, M | 1 |
| Montinaro, AM | 1 |
| Napoli, M | 1 |
1 trial available for clonidine and Edema
| Article | Year |
|---|---|
Evaluation of a muscle relaxant on sequelae of third molar surgery: a pilot study.
Topics: Adolescent; Adult; Clonidine; Edema; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Molar | 2007 |
11 other studies available for clonidine and Edema
| Article | Year |
|---|---|
Regulation of murine arthritis by systemic, spinal, and intra-articular adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Arthritis, Experimental; Ce | 2019 |
Aqueous ethanol extract of the fruit of Xylopia aethiopica (Annonaceae) exhibits anti-anaphylactic and anti-inflammatory actions in mice.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Carrageenan; Catalepsy; Clonid | 2013 |
Pharmacological analysis of alpha(2)-adrenoceptor subtypes mediating analgesic, anti-inflammatory and gastroprotective actions.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon | 2009 |
Recurrent cellulitis associated with long-term intrathecal opioid infusion therapy: a case report and review of the literature.
Topics: Analgesics, Opioid; Baclofen; Cellulitis; Clonidine; Edema; Female; GABA Agonists; Humans; Hydromorp | 2010 |
Clinico-pathologic conference: case 6.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell; | 2009 |
Central and peripheral anti-inflammatory actions by clonidine and a structurally related imidazoline analog.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Brain; Carrageenan; Clonidine; Edema; Histamine; M | 1984 |
Therapeutic and adjunctive applications of an imidazoline anti-inflammatory agent.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Carrageenan; Clonidine; Drug Therapy, | 1983 |
[Special indications for the use of soft contact lenses as a drug-release-system (author's transl)].
Topics: Alcohols; Antihypertensive Agents; Clonidine; Contact Lenses, Hydrophilic; Delayed-Action Preparatio | 1976 |
[Inhibitory effects of clonidine on edema formation after thermal injury in mice and rats].
Topics: Animals; Burns; Capillary Permeability; Clonidine; Edema; Lipid Peroxides; Male; Mice; Rats; Rats, I | 1989 |
Anti-inflammatory actions of clonidine, guanfacine and B-HT 920 against various inflammagen-induced acute paw oedema in rats.
Topics: Animals; Anti-Inflammatory Agents; Azepines; Bradykinin; Carrageenan; Clonidine; Edema; Formaldehyde | 1986 |
Muzolimine in advanced chronic renal failure.
Topics: Acid-Base Imbalance; Acidosis; Adult; Aged; Clonidine; Diuresis; Edema; Female; Glomerular Filtratio | 1985 |