Page last updated: 2024-10-25

clobazam and Pain

clobazam has been researched along with Pain in 2 studies

Clobazam: A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
clobazam : 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substituted by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"The area of static hyperalgesia after intradermal capsaicin injection was the primary endpoint."2.78Evaluation of anti-hyperalgesic and analgesic effects of two benzodiazepines in human experimental pain: a randomized placebo-controlled study. ( Arendt-Nielsen, L; Besson, M; Curatolo, M; Desmeules, J; Vuilleumier, PH, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vuilleumier, PH1
Besson, M1
Desmeules, J1
Arendt-Nielsen, L1
Curatolo, M1
Mimoun, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Gaba-a-Agonists on Pain Mechanisms: An Experimental Study in Healthy Volunteers[NCT01011036]Phase 317 participants (Actual)Interventional2009-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for clobazam and Pain

ArticleYear
Evaluation of anti-hyperalgesic and analgesic effects of two benzodiazepines in human experimental pain: a randomized placebo-controlled study.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Analgesics; Benzodiazepines; Clobazam; Clonazepam; Cross-Sectional Studies; Doubl

2013
[Chronic prostatodynia and psychosomatic care].
    Journal d'urologie, 1992, Volume: 98, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Benzodiazepinones; Ch

1992