choline has been researched along with Cleft Spine in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lumbosacral spina bifida is a common debilitating birth defect whose multiple causes are poorly understood." | 1.38 | Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure. ( Capecchi, MR; Gahring, LC; Rogers, SW; Tvrdik, P, 2012) |
| "Choline is an essential nutrient and it is also a methyl donor critical for the maintenance of cell membrane integrity and methyl metabolism." | 1.33 | CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. ( Enaw, JO; Finnell, RH; Lammer, EJ; Lu, W; Shaw, GM; Yang, W; Zhu, H, 2006) |
| "Significant correlations with maternal preeclampsia and fetal open spina bifida were also observed." | 1.29 | Metabolic profiling of amniotic fluid by proton nuclear magnetic resonance spectroscopy: correlation with fetal maturation and other clinical variables. ( Bock, JL, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, MSI | 1 |
| Nabeka, H | 1 |
| Islam, F | 1 |
| Shimokawa, T | 1 |
| Saito, S | 1 |
| Li, X | 1 |
| Kawabe, S | 1 |
| Hamada, F | 1 |
| Tachibana, T | 1 |
| Matsuda, S | 1 |
| Rogers, SW | 1 |
| Tvrdik, P | 1 |
| Capecchi, MR | 1 |
| Gahring, LC | 1 |
| Pal, K | 1 |
| Sharma, U | 1 |
| Gupta, DK | 1 |
| Pratap, A | 1 |
| Jagannathan, NR | 1 |
| Enaw, JO | 1 |
| Zhu, H | 1 |
| Yang, W | 1 |
| Lu, W | 1 |
| Shaw, GM | 1 |
| Lammer, EJ | 1 |
| Finnell, RH | 1 |
| Bock, JL | 1 |
| Woodard, JC | 1 |
6 other studies available for choline and Cleft Spine
| Article | Year |
|---|---|
Early neonatal loss of inhibitory synaptic input to the spinal motor neurons confers spina bifida-like leg dysfunction in a chicken model.
Topics: Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Caspase 3; Chick Embryo; Chickens; Choline; | 2017 |
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Lineage; Choline; Female; Homologous Recombin | 2012 |
Metabolite profile of cerebrospinal fluid in patients with spina bifida: a proton magnetic resonance spectroscopy study.
Topics: Acetates; Alanine; Cerebrospinal Fluid; Child, Preschool; Choline; Female; Glycerylphosphorylcholine | 2005 |
CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population.
Topics: California; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Female; Genotype; Human | 2006 |
Metabolic profiling of amniotic fluid by proton nuclear magnetic resonance spectroscopy: correlation with fetal maturation and other clinical variables.
Topics: Amino Acids; Amniotic Fluid; Choline; Creatinine; Down Syndrome; Embryonic and Fetal Development; Fe | 1994 |
Effects of deficiencies in labile methyl groups on the growth and development of fetal rats.
Topics: Animals; Choline; Congenital Abnormalities; Deficiency Diseases; Diet; Embryonic and Fetal Developme | 1970 |