chloroquine has been researched along with HIV in 15 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Until late 2015, Botswana recommended preventive treatment for pregnant women in malarial regions with chloroquine and proguanil (CP)." | 4.12 | Impact of prophylactic antimalarials in pregnant women living with Human Immunodeficiency Virus on birth outcomes in Botswana. ( Diseko, M; Lockman, S; Mabuta, J; Makhema, J; Mayondi, G; Melton, ML; Mmalane, M; Olaleye, OA; Shapiro, RL; Zash, R, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, LZ | 1 |
| Hu, SF | 1 |
| Zaw, K | 1 |
| Angerhofer, CK | 1 |
| Chai, H | 1 |
| Pezzuto, JM | 1 |
| Cordell, GA | 1 |
| Lin, J | 1 |
| Zheng, DM | 1 |
| Gochfeld, DJ | 1 |
| Hamann, MT | 1 |
| Casano, G | 1 |
| Dumètre, A | 1 |
| Pannecouque, C | 1 |
| Hutter, S | 1 |
| Azas, N | 1 |
| Robin, M | 1 |
| Olaleye, OA | 1 |
| Zash, R | 1 |
| Diseko, M | 1 |
| Mayondi, G | 1 |
| Mabuta, J | 1 |
| Lockman, S | 1 |
| Melton, ML | 1 |
| Mmalane, M | 1 |
| Makhema, J | 1 |
| Shapiro, RL | 1 |
| Brest, P | 1 |
| Benzaquen, J | 1 |
| Klionsky, DJ | 1 |
| Hofman, P | 1 |
| Mograbi, B | 1 |
| Cui, X | 1 |
| Sun, J | 1 |
| Minkove, SJ | 1 |
| Li, Y | 1 |
| Cooper, D | 1 |
| Couse, Z | 1 |
| Eichacker, PQ | 1 |
| Torabi-Parizi, P | 1 |
| Harrison, MJ | 1 |
| Brice, N | 1 |
| Scott, C | 1 |
| Bernard, MA | 1 |
| Han, X | 1 |
| Inderbitzin, S | 1 |
| Agbim, I | 1 |
| Zhao, H | 1 |
| Koziel, H | 1 |
| Tachado, SD | 1 |
| Vijaykumar, TS | 1 |
| Nath, A | 1 |
| Chauhan, A | 1 |
| Scheller, C | 1 |
| Ullrich, A | 1 |
| McPherson, K | 1 |
| Hefele, B | 1 |
| Knöferle, J | 1 |
| Lamla, S | 1 |
| Olbrich, AR | 1 |
| Stocker, H | 1 |
| Arasteh, K | 1 |
| ter Meulen, V | 1 |
| Rethwilm, A | 1 |
| Koutsilieri, E | 1 |
| Dittmer, U | 1 |
| Parris, GE | 2 |
| Anderson, DC | 1 |
| Nichols, E | 1 |
| Manger, R | 1 |
| Woodle, D | 1 |
| Barry, M | 1 |
| Fritzberg, AR | 1 |
| Madhavankutty, K | 1 |
| Shyamasundar, K | 1 |
| Andrews, W | 1 |
| Frankel, AD | 1 |
| Pabo, CO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Observational Study for the Evaluation of the Role of HIV-1 Tat Protein and Anti-Tat Immune Response in Peripheral Blood HIV Reservoir Dynamics[NCT04263207] | 100 participants (Anticipated) | Observational | 2020-02-04 | Suspended (stopped due to Study halted prematurely due to the difficulties in dedicating the human resources necessary to conduct the study deriving from the COVID-19 pandemic, but potentially will resume) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for chloroquine and HIV
| Article | Year |
|---|---|
Effects of chloroquine or hydroxychloroquine treatment on non-SARS-CoV2 viral infections: A systematic review of clinical studies.
Topics: Alphapapillomavirus; Antiviral Agents; Chikungunya Fever; Chikungunya virus; Chloroquine; COVID-19; | 2021 |
Clinical Features of HIV Arthropathy in Children: A Case Series and Literature Review.
Topics: Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; CD4 Lymph | 2021 |
13 other studies available for chloroquine and HIV
| Article | Year |
|---|---|
Thalifaberidine, a cytotoxic aporphine-benzylisoquinoline alkaloid from Thalictrum faberi.
Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Aporphines; Drugs, Chinese Her | 1994 |
Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp.
Topics: Animals; Antimalarials; Bromobenzenes; Chromatography, High Pressure Liquid; Colonic Neoplasms; Diox | 2001 |
Anti-HIV and antiplasmodial activity of original flavonoid derivatives.
Topics: Anti-HIV Agents; Antimalarials; Cell Line; Cell Survival; Flavonoids; HIV; HIV Infections; Humans; M | 2010 |
Impact of prophylactic antimalarials in pregnant women living with Human Immunodeficiency Virus on birth outcomes in Botswana.
Topics: Antimalarials; Botswana; Chloroquine; Female; HIV; HIV Infections; Humans; Infant, Newborn; Malaria; | 2022 |
Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype?
Topics: Anti-Inflammatory Agents; Antiviral Agents; Autophagy; Chloroquine; COVID-19; COVID-19 Drug Treatmen | 2020 |
HIV-derived ssRNA binds to TLR8 to induce inflammation-driven macrophage foam cell formation.
Topics: Antibodies, Neutralizing; Bronchoalveolar Lavage Fluid; Chloroquine; Endocytosis; Endosomes; Foam Ce | 2014 |
Chloroquine mediated molecular tuning of astrocytes for enhanced permissiveness to HIV infection.
Topics: Antirheumatic Agents; Astrocytes; Brain; Cells, Cultured; Chloroquine; Enzyme Inhibitors; HIV; HIV I | 2008 |
CpG oligodeoxynucleotides activate HIV replication in latently infected human T cells.
Topics: Amino Acid Motifs; Chloroquine; CpG Islands; DNA-Binding Proteins; Dose-Response Relationship, Drug; | 2004 |
Update on hypothesis linking chloroquine-resistant malaria to disease-causing HIV.
Topics: Antimalarials; Chloroquine; Drug Resistance; HIV; HIV Infections; Humans; Malaria; Models, Biologica | 2006 |
The timing is right: Evolution of AIDS-causing HIV strains is consistent with history of chloroquine use.
Topics: Acquired Immunodeficiency Syndrome; Chloroquine; HIV; HIV Infections; Humans | 2006 |
Tumor cell retention of antibody Fab fragments is enhanced by an attached HIV TAT protein-derived peptide.
Topics: Amino Acid Sequence; Biological Transport; Carbon Radioisotopes; Cell Membrane; Chloroquine; Colonic | 1993 |
From pseudocholinesterase to human immunodeficiency virus.
Topics: Animals; Antibodies; Apolipoproteins E; Biochemistry; Butyrylcholinesterase; Chloroquine; Drug Carri | 1995 |
Cellular uptake of the tat protein from human immunodeficiency virus.
Topics: Animals; Cell Line; Cells, Cultured; Chloroquine; Gene Expression Regulation; Gene Products, tat; HI | 1988 |