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celecoxib and Obesity

celecoxib has been researched along with Obesity in 13 studies

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" We evaluated rates of acute kidney injury (AKI) in primary and revision TJA using a multimodal pain control regimen including scheduled celecoxib and PRN ketorolac."7.83Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib. ( Callaghan, JJ; Hogue, MH; Klaassen, AL; Liu, SS; Noiseux, NO; Warth, LC, 2016)
"We investigated the effects of metformin and celecoxib on obesity-induced adipose tissue inflammation, insulin resistance (IR), fatty liver, and high blood pressure in high-fat (HF) fed rats."7.83Additional effect of metformin and celecoxib against lipid dysregulation and adipose tissue inflammation in high-fat fed rats with insulin resistance and fatty liver. ( Hsieh, PS; Hung, YJ; Lu, CH, 2016)
" We evaluated rates of acute kidney injury (AKI) in primary and revision TJA using a multimodal pain control regimen including scheduled celecoxib and PRN ketorolac."3.83Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib. ( Callaghan, JJ; Hogue, MH; Klaassen, AL; Liu, SS; Noiseux, NO; Warth, LC, 2016)
"We investigated the effects of metformin and celecoxib on obesity-induced adipose tissue inflammation, insulin resistance (IR), fatty liver, and high blood pressure in high-fat (HF) fed rats."3.83Additional effect of metformin and celecoxib against lipid dysregulation and adipose tissue inflammation in high-fat fed rats with insulin resistance and fatty liver. ( Hsieh, PS; Hung, YJ; Lu, CH, 2016)
" The whole body insulin resistance of HFa indicated by the increased fasting plasma insulin levels and the elevated area under curve of insulin obtained from the oral glucose tolerance test were significantly reversed in those combined with celecoxib and nimesulid administration compared with those in HFr."3.77The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in high-fat-fed rats. ( Chen, CH; Hsia, TL; Hsieh, CH; Hsieh, PS; Huang, DW; Tian, YF, 2011)
" After treatment with celecoxib, the hypertension was attenuated (MAP=126±2 mm Hg) in obese rats without changes in HR."3.76Cox-2 inhibition attenuates cardiovascular and inflammatory aspects in monosodium glutamate-induced obese rats. ( Cecchini, R; Cunha, NV; de Abreu, SB; Grassiolli, S; Guarnier, FA; Martins-Pinge, MC; Mazzuco, TL; Panis, C; Pinge-Filho, P, 2010)
"Treatment with celecoxib resulted in G1 cell cycle arrest, induction of apoptosis, inhibition of cellular adhesion and invasion and reduction of expression of hTERT mRNA and COX-2 protein in all of the ovarian cancer cell lines."1.43The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer. ( Bae-Jump, VL; Gehrig, PA; Han, X; Jones, HM; Schuler, KM; Sheng, X; Suri, A; Zhong, Y; Zhou, C, 2016)
"Body weight was increased significantly and similarly in HFa, HFa-Cel, and HFa-Mes."1.35COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver. ( Chan, PC; Chen, CH; Chiang, CF; Hsieh, PS; Jin, JS; Shih, KC, 2009)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's10 (76.92)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Ghazala, RA1
El Medney, A1
Meleis, A1
Mohie El Dien, P1
Samir, H1
Latif, D1
Darweesh, FF1
Osman, OM1
Abdelhakim, AM1
Nabil, H1
Ashour, ASA1
Kurhe, Y1
Mahesh, R1
Gupta, D1
Warth, LC1
Noiseux, NO1
Hogue, MH1
Klaassen, AL1
Liu, SS1
Callaghan, JJ1
Suri, A1
Sheng, X1
Schuler, KM1
Zhong, Y1
Han, X1
Jones, HM1
Gehrig, PA1
Zhou, C1
Bae-Jump, VL1
Lu, CH1
Hung, YJ1
Hsieh, PS4
Jin, JS1
Chiang, CF2
Chan, PC1
Chen, CH3
Shih, KC1
Lu, KC1
Cunha, NV1
de Abreu, SB1
Panis, C1
Grassiolli, S2
Guarnier, FA1
Cecchini, R1
Mazzuco, TL1
Pinge-Filho, P2
Martins-Pinge, MC2
Tian, YF1
Hsia, TL1
Hsieh, CH1
Huang, DW1
da Cunha, NV1
Barbosa Neto, O1
Le, P1
Kawai, M1
Bornstein, S1
DeMambro, VE1
Horowitz, MC1
Rosen, CJ1
Blackler, R1
Syer, S1
Bolla, M1
Ongini, E1
Wallace, JL1

Trials

1 trial available for celecoxib and Obesity

ArticleYear
Oral tramadol versus oral celecoxib for analgesia after mediolateral episiotomy repair in obese primigravidae: a randomized controlled trial.
    International urogynecology journal, 2021, Volume: 32, Issue:9

    Topics: Analgesia; Analgesics, Opioid; Celecoxib; Double-Blind Method; Episiotomy; Female; Humans; Obesity;

2021

Other Studies

12 other studies available for celecoxib and Obesity

ArticleYear
Role of anti-inflammatory interventions in high-fat-diet-induced obesity.
    Biomedical chromatography : BMC, 2020, Volume: 34, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Celecoxib; Cytokines; Diet, High-Fat; Disease Models, Animal; Fat

2020
Effect of a selective cyclooxygenase type 2 inhibitor celecoxib on depression associated with obesity in mice: an approach using behavioral tests.
    Neurochemical research, 2014, Volume: 39, Issue:7

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Celecoxib; Cyclooxygenase 2 Inhibitors; Depression

2014
Risk of Acute Kidney Injury After Primary and Revision Total Hip Arthroplasty and Total Knee Arthroplasty Using a Multimodal Approach to Perioperative Pain Control Including Ketorolac and Celecoxib.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:1

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Arthro

2016
The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer.
    Oncotarget, 2016, Jun-28, Volume: 7, Issue:26

    Topics: Animals; Apoptosis; BRCA1 Protein; Celecoxib; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Prol

2016
Additional effect of metformin and celecoxib against lipid dysregulation and adipose tissue inflammation in high-fat fed rats with insulin resistance and fatty liver.
    European journal of pharmacology, 2016, Oct-15, Volume: 789

    Topics: Adipocytes; Adipokines; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Blood Pressure; Body

2016
COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver.
    Obesity (Silver Spring, Md.), 2009, Volume: 17, Issue:6

    Topics: Adipocytes; Adipogenesis; Adipose Tissue; Animals; Blood Glucose; Body Weight; Celecoxib; Cell Size;

2009
Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats.
    European journal of clinical investigation, 2010, Volume: 40, Issue:2

    Topics: Adiposity; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blood Glucose; Blood Pr

2010
Cox-2 inhibition attenuates cardiovascular and inflammatory aspects in monosodium glutamate-induced obese rats.
    Life sciences, 2010, Sep-11, Volume: 87, Issue:11-12

    Topics: Adipose Tissue; Animals; Blood; Blood Pressure; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibi

2010
The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in high-fat-fed rats.
    Life sciences, 2011, Jul-18, Volume: 89, Issue:3-4

    Topics: Adipose Tissue; Animals; Biomarkers; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diet, R

2011
COX-2 inhibition does not reverse the increased sympathetic modulation in MSG obese rats.
    Autonomic neuroscience : basic & clinical, 2011, Dec-07, Volume: 165, Issue:2

    Topics: Animals; Blood Pressure; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Food Additives; H

2011
A high-fat diet induces bone loss in mice lacking the Alox5 gene.
    Endocrinology, 2012, Volume: 153, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Bone Density; Bone Resorption; Celecoxib; Cyclooxygenase 2; Cy

2012
Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Celecoxib; Drug Therapy, Combi

2012