Page last updated: 2024-10-17

bupropion and Aura

bupropion has been researched along with Aura in 6 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Research Excerpts

ExcerptRelevanceReference
"Bupropion hydrochloride (Zyban) is prescribed for smoking cessation."3.72[Bupropion-induced epileptic seizures]. ( Baldy-Moulinier, M; Crespel, A; Gélisse, P; Kuate, C, 2004)
"Preferred drugs for treating depression in epilepsy are serotonin reuptake inhibitors."2.49[Antidepressants in epilepsy]. ( Castaño-Monsalve, B, 2013)
"With conservative dosing and close monitoring, combinations of SRIs with bupropion in this uncontrolled clinical series appeared to be safe and often more effective than monotherapy."1.30Combining serotonin reuptake inhibitors and bupropion in partial responders to antidepressant monotherapy. ( Baldessarini, RJ; Bodkin, JA; Gardner, DM; Lasser, RA; Wines, JD, 1997)
"Amitriptyline was the most effective antidepressant, attenuating both seizure severity and afterdischarge duration."1.27Acute effects of antidepressants on hippocampal seizures. ( Clifford, DB; Hicks, FG; Rutherford, JL; Zorumski, CF, 1985)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castaño-Monsalve, B1
Noda, AH1
Schu, U1
Maier, T1
Knake, S1
Rosenow, F1
Kuate, C1
Gélisse, P1
Baldy-Moulinier, M1
Crespel, A1
Jefferson, JW1
Bodkin, JA1
Lasser, RA1
Wines, JD1
Gardner, DM1
Baldessarini, RJ1
Clifford, DB1
Rutherford, JL1
Hicks, FG1
Zorumski, CF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-Blind, Placebo-Controlled, Randomized Trial of Adjunctive Lisdexamfetamine Dimesylate in Residual Symptoms of Major Depressive Disorder Partially Responsive to Selective Serotonin or Norepinephrine Reuptake Inhibitor Monotherapy[NCT01148979]Phase 435 participants (Actual)Interventional2010-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in the Dysphoric Apathy/Retardation Sub-factor (MDAR) of Montgomery-Asberg Depression Rating Scale (MADRS) at 4 Weeks.

The Montgomery-Asberg Depression Rating Scale Dysphoric Apathy Retardation subfactor (MDAR) is a 5-item subscale of the clinician-administered 10-item Montgomery-Asberg Depression Rating Scale (MADRS). MDAR score can range from 0-30 with a higher score representing a greater severity of depressive symptoms. (NCT01148979)
Timeframe: Baseline to 4 weeks of treatment

,
Interventionscores on a scale (Mean)
Baseline Mean MDAR scoreWeek 4 Mean MDAR scoreChange from BL in mean MDAR score
Lisdexamfetamine Dimesylate (Vyvanse)13.466.36-7.08
Placebo Adjunct12.579.08-3.49

Reviews

1 review available for bupropion and Aura

ArticleYear
[Antidepressants in epilepsy].
    Revista de neurologia, 2013, Aug-01, Volume: 57, Issue:3

    Topics: Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bupropion; Clinical Trials

2013

Other Studies

5 other studies available for bupropion and Aura

ArticleYear
Epileptic seizures, coma and EEG burst-suppression from suicidal bupropion intoxication.
    Epileptic disorders : international epilepsy journal with videotape, 2017, Mar-01, Volume: 19, Issue:1

    Topics: Bupropion; Coma; Depressive Disorder, Major; Electroencephalography; Epilepsy; Female; Humans; Middl

2017
[Bupropion-induced epileptic seizures].
    Revue neurologique, 2004, Volume: 160, Issue:6-7

    Topics: Adult; Bupropion; Dopamine Uptake Inhibitors; Electroencephalography; Epilepsy; Female; Humans; Smok

2004
Psychotropic medications and their effects on sexual function.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:11

    Topics: Bupropion; Epilepsy; Female; Humans; Male; Psychotropic Drugs; Selective Serotonin Reuptake Inhibito

1995
Combining serotonin reuptake inhibitors and bupropion in partial responders to antidepressant monotherapy.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:4

    Topics: 1-Naphthylamine; Adult; Aged; Ambulatory Care; Anxiety Disorders; Bupropion; Depressive Disorder; Dr

1997
Acute effects of antidepressants on hippocampal seizures.
    Annals of neurology, 1985, Volume: 18, Issue:6

    Topics: Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Bupropion; Desipramine; Epilepsy; Hi

1985