brivudine and Iritis

brivudine has been researched along with Iritis* in 2 studies

Other Studies

2 other study(ies) available for brivudine and Iritis

Article	Year
Ocular penetration and efficacy of chloroethyldeoxyuridine against herpetic keratouveitis. Investigative ophthalmology & visual science, 1986, Volume: 27, Issue:10 Topical administration of 0.1% or 1% chloroethyldeoxyuridine eyedrops caused a significant reduction in the severity of experimental herpes simplex iritis and stromal keratitis in rabbits. The healing effect caused by chloroethyldeoxyuridine was comparable to that obtained with 0.1% and 0.5% bromovinylde-oxyuridine eyedrops. The drug levels achieved in the anterior chamber fluid following topical application of 1% eyedrops of [2-14C]CEDU, a radiolabelled analogue of chloroethyldeoxyuridine, were well above the minimum concentration (0.1 microgram/mL) required for inhibition of herpes simplex virus type 1 replication. The beneficial effects of chloroethyldeoxyuridine on stomal keratitis and iritis appear consistent with its efficient penetration through the cornea. Topics: Animals; Anterior Chamber; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Iritis; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits	1986
Oral and topical treatment of experimental herpes simplex iritis with bromovinyldeoxyuridine. Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:8 Topics: Administration, Oral; Animals; Antiviral Agents; Betamethasone; Bromodeoxyuridine; Drug Synergism; Drug Therapy, Combination; Iritis; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Trifluridine	1982

Article

Year

Ocular penetration and efficacy of chloroethyldeoxyuridine against herpetic keratouveitis.

Investigative ophthalmology & visual science, 1986, Volume: 27, Issue:10

Topical administration of 0.1% or 1% chloroethyldeoxyuridine eyedrops caused a significant reduction in the severity of experimental herpes simplex iritis and stromal keratitis in rabbits. The healing effect caused by chloroethyldeoxyuridine was comparable to that obtained with 0.1% and 0.5% bromovinylde-oxyuridine eyedrops. The drug levels achieved in the anterior chamber fluid following topical application of 1% eyedrops of [2-14C]CEDU, a radiolabelled analogue of chloroethyldeoxyuridine, were well above the minimum concentration (0.1 microgram/mL) required for inhibition of herpes simplex virus type 1 replication. The beneficial effects of chloroethyldeoxyuridine on stomal keratitis and iritis appear consistent with its efficient penetration through the cornea.

Topics: Animals; Anterior Chamber; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Iritis; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits

1986

Oral and topical treatment of experimental herpes simplex iritis with bromovinyldeoxyuridine.

Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:8

Topics: Administration, Oral; Animals; Antiviral Agents; Betamethasone; Bromodeoxyuridine; Drug Synergism; Drug Therapy, Combination; Iritis; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Trifluridine

1982