Page last updated: 2024-10-23

berberine and Glioma

berberine has been researched along with Glioma in 10 studies

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"The cytotoxicity of berberine on C6 rat glioma cells indicated that berberine induced morphological changes and caused cell death through G2/M arrest and apoptosis."7.75Involvement of reactive oxygen species and caspase-dependent pathway in berberine-induced cell cycle arrest and apoptosis in C6 rat glioma cells. ( Chen, GW; Chen, TC; Chiu, TH; Chung, JG; Hsia, TC; Lai, KC; Liao, CL; Lin, HJ; Lin, JJ; Tang, YJ; Yang, JS, 2009)
" Here, we investigated the effect of the natural alkaloid berberine on As2O3-mediated inhibition of cancer cell migration using rat and human glioma cell lines."7.74Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide. ( Chou, FP; Kuo, HC; Lin, TH; Lu, FJ, 2008)
"Berberine is a protoberberine alkaloid with wide range of pharmacological activities, applicable to various pathological conditions."6.72Therapeutic Potential of Berberine in the Treatment of Glioma: Insights into Its Regulatory Mechanisms. ( Asemi, Z; Behnam, M; Mirzaei, H; Pourattar, MA; Razavi, ZS; Tamtaji, OR, 2021)
"Chemotherapy is a conventional treatment for glioma, but its efficacy is greatly limited due to low blood-brain barrier (BBB) permeability and lack of specificity."5.72Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma. ( Chen, J; Hai, L; Liu, Q; Lu, R; Wang, S; Wu, Y; Yang, C; Yang, Z, 2022)
"Berberine could inhibit the migration and invasion of glioma cells by suppressing the TGF-β1/COL11A1 pathway and changes actin cytoskeleton arrangement."5.72Berberine inhibits glioma cell migration and invasion by suppressing TGF-β1/COL11A1 pathway. ( Cao, J; Chen, Y; Gao, H; Huang, H; Lai, J; Li, C; Liu, Z; Sun, Y; Zhan, Z; Zhang, C, 2022)
"Berberine is a promising natural drug that has a potential therapeutic effect on neurodegenerative diseases."5.56Berberine Induces CYP2J2 Expression in Human U251 Glioma Cells via Regulation of Peroxisome Proliferator-Activated Receptor Alpha. ( Gong, J; Shi, J; Wang, J; Wang, S; Yu, S; Yu, X, 2020)
"Berberine (BBR) was the potential drug for anti-tumor in glioma cells."5.56Glucose-coated Berberine Nanodrug for Glioma Therapy through Mitochondrial Pathway. ( An, J; Dong, W; He, Y; Jia, X; Jia, Y; Liu, K; Ma, X; Pan, Y; Sheng, J; Wang, B; Wang, J; Wang, S; Wang, X; Wu, Y; Yu, D; Yu, W; Zhao, Y; Zhu, W, 2020)
"The cytotoxicity of berberine on C6 rat glioma cells indicated that berberine induced morphological changes and caused cell death through G2/M arrest and apoptosis."3.75Involvement of reactive oxygen species and caspase-dependent pathway in berberine-induced cell cycle arrest and apoptosis in C6 rat glioma cells. ( Chen, GW; Chen, TC; Chiu, TH; Chung, JG; Hsia, TC; Lai, KC; Liao, CL; Lin, HJ; Lin, JJ; Tang, YJ; Yang, JS, 2009)
" Here, we investigated the effect of the natural alkaloid berberine on As2O3-mediated inhibition of cancer cell migration using rat and human glioma cell lines."3.74Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide. ( Chou, FP; Kuo, HC; Lin, TH; Lu, FJ, 2008)
"Berberine is a protoberberine alkaloid with wide range of pharmacological activities, applicable to various pathological conditions."2.72Therapeutic Potential of Berberine in the Treatment of Glioma: Insights into Its Regulatory Mechanisms. ( Asemi, Z; Behnam, M; Mirzaei, H; Pourattar, MA; Razavi, ZS; Tamtaji, OR, 2021)
"Chemotherapy is a conventional treatment for glioma, but its efficacy is greatly limited due to low blood-brain barrier (BBB) permeability and lack of specificity."1.72Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma. ( Chen, J; Hai, L; Liu, Q; Lu, R; Wang, S; Wu, Y; Yang, C; Yang, Z, 2022)
"Berberine could inhibit the migration and invasion of glioma cells by suppressing the TGF-β1/COL11A1 pathway and changes actin cytoskeleton arrangement."1.72Berberine inhibits glioma cell migration and invasion by suppressing TGF-β1/COL11A1 pathway. ( Cao, J; Chen, Y; Gao, H; Huang, H; Lai, J; Li, C; Liu, Z; Sun, Y; Zhan, Z; Zhang, C, 2022)
"Berberine is a promising natural drug that has a potential therapeutic effect on neurodegenerative diseases."1.56Berberine Induces CYP2J2 Expression in Human U251 Glioma Cells via Regulation of Peroxisome Proliferator-Activated Receptor Alpha. ( Gong, J; Shi, J; Wang, J; Wang, S; Yu, S; Yu, X, 2020)
"Berberine (BBR) was the potential drug for anti-tumor in glioma cells."1.56Glucose-coated Berberine Nanodrug for Glioma Therapy through Mitochondrial Pathway. ( An, J; Dong, W; He, Y; Jia, X; Jia, Y; Liu, K; Ma, X; Pan, Y; Sheng, J; Wang, B; Wang, J; Wang, S; Wang, X; Wu, Y; Yu, D; Yu, W; Zhao, Y; Zhu, W, 2020)
"Berberine was evaluated for antitumor activity against malignant brain tumors."1.28Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors. ( Dougherty, DV; Rosenblum, ML; Zhang, RX, 1990)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's5 (50.00)2.80

Authors

AuthorsStudies
Yang, C1
Yang, Z1
Wang, S3
Chen, J1
Liu, Q1
Hai, L1
Lu, R1
Wu, Y2
Sun, Y2
Huang, H2
Zhan, Z1
Gao, H1
Zhang, C2
Lai, J1
Cao, J2
Li, C1
Chen, Y2
Liu, Z1
Yu, X1
Wang, J2
Gong, J1
Shi, J1
Yu, S1
Asemi, Z1
Behnam, M1
Pourattar, MA1
Mirzaei, H1
Razavi, ZS1
Tamtaji, OR1
An, J1
Dong, W1
Wang, X1
Sheng, J1
Jia, Y1
He, Y1
Ma, X1
Yu, D1
Jia, X1
Wang, B1
Yu, W1
Liu, K1
Zhao, Y1
Zhu, W1
Pan, Y1
Yu, J1
Liu, X2
Li, G1
Chen, TC1
Lai, KC1
Yang, JS1
Liao, CL1
Hsia, TC1
Chen, GW1
Lin, JJ1
Lin, HJ1
Chiu, TH1
Tang, YJ1
Chung, JG1
Lin, TH1
Kuo, HC1
Chou, FP1
Lu, FJ1
Novak, JE1
Agranoff, BW1
Fisher, SK1
Zhang, RX1
Dougherty, DV1
Rosenblum, ML1

Reviews

1 review available for berberine and Glioma

ArticleYear
Therapeutic Potential of Berberine in the Treatment of Glioma: Insights into Its Regulatory Mechanisms.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Berberine; Brain Neoplasms; Cell Proliferatio

2021

Other Studies

9 other studies available for berberine and Glioma

ArticleYear
Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma.
    Bioorganic & medicinal chemistry, 2022, 09-01, Volume: 69

    Topics: Berberine; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Glioma; Humans; Hyd

2022
Berberine inhibits glioma cell migration and invasion by suppressing TGF-β1/COL11A1 pathway.
    Biochemical and biophysical research communications, 2022, 10-15, Volume: 625

    Topics: Animals; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Collagen Type XI;

2022
Berberine Induces CYP2J2 Expression in Human U251 Glioma Cells via Regulation of Peroxisome Proliferator-Activated Receptor Alpha.
    Pharmacology, 2020, Volume: 105, Issue:5-6

    Topics: Berberine; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System;

2020
Glucose-coated Berberine Nanodrug for Glioma Therapy through Mitochondrial Pathway.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Biological Transport; Blood-Brain Barrier; Bra

2020
Oncosis-like cell death is induced by berberine through ERK1/2-mediated impairment of mitochondrial aerobic respiration in gliomas.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102

    Topics: Adenosine Triphosphate; Aerobiosis; Animals; Apoptosis; Autophagy; Berberine; Brain Neoplasms; Cell

2018
Involvement of reactive oxygen species and caspase-dependent pathway in berberine-induced cell cycle arrest and apoptosis in C6 rat glioma cells.
    International journal of oncology, 2009, Volume: 34, Issue:6

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Berberine; Blotting, Western; Calcium; Caspase Inhib

2009
Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide.
    BMC cancer, 2008, Feb-25, Volume: 8

    Topics: Actins; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Berberine; Cell Line, Tumor; C

2008
Increased expression of Galpha(q/11) and of phospholipase-Cbeta1/4 in differentiated human NT2-N neurons: enhancement of phosphoinositide hydrolysis.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Animals; Antineoplastic Agents; Berberine; Brain; Cell Differentiation; Glioma; GTP-Binding Protein

2000
Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors.
    Chinese medical journal, 1990, Volume: 103, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Berberine; Brain Neo

1990