Page last updated: 2024-10-23

berberine and Aging

berberine has been researched along with Aging in 12 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to investigate the protective effects of berberine (BBR) against D-galactose (D-gal)-induced renal aging in rats, pointing to its ability to modulate phosphatase and tensin homolog deleted on chromosome ten (PTEN)/Akt signalling, and to attenuate oxidative stress, inflammation and apoptosis."7.96Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a PTEN/Akt-dependent mechanism. ( El-Horany, HE; Gaballah, HH; Helal, DS, 2020)
"The results showed that administration of berberine for 6 months significantly improved cognitive deficits and insulin resistance in naturally aging rats (p<0."7.88Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats. ( Chen, L; Guan, F; Guan, Y; Li, J; Lv, X; Teng, F; Xu, J; Yu, Y; Zhang, M; Zhao, Y, 2018)
"This study aimed to investigate the protective effects of berberine (BBR) against D-galactose (D-gal)-induced renal aging in rats, pointing to its ability to modulate phosphatase and tensin homolog deleted on chromosome ten (PTEN)/Akt signalling, and to attenuate oxidative stress, inflammation and apoptosis."3.96Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a PTEN/Akt-dependent mechanism. ( El-Horany, HE; Gaballah, HH; Helal, DS, 2020)
"The results showed that administration of berberine for 6 months significantly improved cognitive deficits and insulin resistance in naturally aging rats (p<0."3.88Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats. ( Chen, L; Guan, F; Guan, Y; Li, J; Lv, X; Teng, F; Xu, J; Yu, Y; Zhang, M; Zhao, Y, 2018)
"Berberine, as an alkaloid found in many Chinese herbs, improves vascular functions in patients with cardiovascular diseases."3.81Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice. ( Guo, T; Peng, QS; Wang, J; Wang, SX; Yue, SW, 2015)
"Fibrosis is a general term encompassing a plethora of pathologies that span all systems and is marked by increased deposition of collagen."2.53AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation. ( Beauloye, C; Bertrand, L; Daskalopoulos, EP; Dufeys, C; Horman, S, 2016)
"Berberine treatment during the ongoing infection did not influence its outcome (from +2 to +10 day)."1.30Influence of berberine on T-cell mediated immunity. ( Hristova, M; Ivanovska, N; Philipov, S, 1999)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Wang, L1
Tang, XQ1
Shi, Y1
Li, HM1
Meng, ZY1
Chen, H1
Li, XH1
Chen, YC1
Liu, H1
Hong, Y1
Xu, HH1
Liu, L1
Zhao, L1
Han, WN1
Liu, X1
Zhang, Y1
Yu, Y1
Zhao, Y1
Teng, F1
Li, J1
Guan, Y1
Xu, J1
Lv, X1
Guan, F1
Zhang, M1
Chen, L1
El-Horany, HE1
Gaballah, HH1
Helal, DS1
Wang, J1
Guo, T1
Peng, QS1
Yue, SW1
Wang, SX1
Daskalopoulos, EP1
Dufeys, C1
Bertrand, L1
Beauloye, C1
Horman, S1
Zhang, Z1
Li, X1
Li, F1
An, L1
Gold, AB1
Keller, AB1
Perry, DC1
Li, H1
Miyahara, T1
Tezuka, Y1
Tran, QL1
Seto, H1
Kadota, S1
Zsilla, G1
Zelles, T1
Mike, A1
Kékes-Szabó, A1
Milusheva, E1
Vizi, ES1
Ivanovska, N1
Philipov, S1
Hristova, M1
Berlin, G1
Enerbäck, L1
Umeda, M1
Amagaya, S1
Ogihara, Y1

Reviews

1 review available for berberine and Aging

ArticleYear
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.
    Journal of molecular and cellular cardiology, 2016, Volume: 91

    Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Berberine; Cardiomegaly; Extracell

2016

Other Studies

11 other studies available for berberine and Aging

ArticleYear
Tetrahydroberberrubine retards heart aging in mice by promoting PHB2-mediated mitophagy.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:2

    Topics: Aging; Animals; Berberine; Cardiomyopathies; Mice; Mitophagy; Signal Transduction

2023
Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats.
    The journal of nutrition, health & aging, 2018, Volume: 22, Issue:6

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Berberine; Cognition; Cognitive Dysfunction; Diet, Hi

2018
Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a PTEN/Akt-dependent mechanism.
    Archives of physiology and biochemistry, 2020, Volume: 126, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aging; Animals; Anti-Inflammatory Agents; Antioxi

2020
Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice.
    Journal of cellular and molecular medicine, 2015, Volume: 19, Issue:11

    Topics: Aging; Animals; Berberine; Blood Pressure; Cardiovascular Diseases; Hypertension; Mice; Organ Cultur

2015
Berberine alleviates postoperative cognitive dysfunction by suppressing neuroinflammation in aged mice.
    International immunopharmacology, 2016, Volume: 38

    Topics: Aged; Aging; Animals; Anti-Inflammatory Agents; Berberine; Calcium-Binding Proteins; Cell Line; Cogn

2016
Prenatal exposure of rats to nicotine causes persistent alterations of nicotinic cholinergic receptors.
    Brain research, 2009, Jan-23, Volume: 1250

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Berberine; Brain; Cerebral Cortex; Corpus Striatum;

2009
Effect of berberine on bone mineral density in SAMP6 as a senile osteoporosis model.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:1

    Topics: Aging; Animals; Berberine; Bone Density; Disease Models, Animal; Female; Hydrastis; Male; Mice; Mice

2003
Differential changes in presynaptic modulation of transmitter release during aging.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1994, Volume: 12, Issue:2

    Topics: Acetylcholine; Aging; Animals; Berberine; Dopamine; Feedback; Female; Frontal Lobe; Hippocampus; Mal

1994
Influence of berberine on T-cell mediated immunity.
    Immunopharmacology and immunotoxicology, 1999, Volume: 21, Issue:4

    Topics: Aging; Animals; Arthritis, Experimental; Berberine; Candida albicans; Candidiasis; Dose-Response Rel

1999
Changes in numbers and heparin content of peritoneal fluid mast cells of growing rats measured by flow cytofluorometry.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1978, Volume: 26, Issue:1

    Topics: Aging; Animals; Ascitic Fluid; Berberine; Cell Count; Computers; Female; Heparin; Mast Cells; Rats;

1978
Effect of shosaikoto, daisaikoto and sannoshashinto (traditional Japanese and Chinese medicines) on experimental hyperlipidemia in rats.
    Journal of ethnopharmacology, 1989, Volume: 26, Issue:3

    Topics: Aging; Animals; Berberine; Cholesterol; Cholesterol, Dietary; Drug Combinations; Drugs, Chinese Herb

1989