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azelastine and Cough

azelastine has been researched along with Cough in 8 studies

azelastine: azeptin is azelastine hydrochloride; structure; eye drop formulation effective in relieving symptoms of allergic conjunctivitis; do not confuse with 5-loxin which is an extract of Boswellia
azelastine : A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"To assess the effects of azelastine in patients with cough-variant asthma, we measured the cough threshold for capsaicin (the concentration required to elicit more than five coughs) in 16 patients with cough-variant asthma before and after 4 weeks of treatment with azelastine (2 mg; b."9.08Cough threshold for capsaicin increases by azelastine in patients with cough-variant asthma. ( Ito, N; Kagaya, M; Kashima, M; Miura, M; Sano, M; Sasaki, M; Shindo, T; Shioya, T, 1996)
"To investigate the efficacy of azelastine hydrochloride (azelastine, CAS 79307-93-0, Azeptin) in suppressing cough, 22 bronchial asthma patients complaining mainly of cough were given the drug for four weeks."9.08Antitussive effect of azelastine hydrochloride in patients with bronchial asthma. ( Ito, N; Kagaya, M; Kimura, K; Miura, M; Miura, S; Sano, M; Shindo, T; Shioya, T; Watanabe, A, 1998)
"To assess the effects of azelastine in patients with cough-variant asthma, we measured the cough threshold for capsaicin (the concentration required to elicit more than five coughs) in 16 patients with cough-variant asthma before and after 4 weeks of treatment with azelastine (2 mg; b."5.08Cough threshold for capsaicin increases by azelastine in patients with cough-variant asthma. ( Ito, N; Kagaya, M; Kashima, M; Miura, M; Sano, M; Sasaki, M; Shindo, T; Shioya, T, 1996)
"To investigate the efficacy of azelastine hydrochloride (azelastine, CAS 79307-93-0, Azeptin) in suppressing cough, 22 bronchial asthma patients complaining mainly of cough were given the drug for four weeks."5.08Antitussive effect of azelastine hydrochloride in patients with bronchial asthma. ( Ito, N; Kagaya, M; Kimura, K; Miura, M; Miura, S; Sano, M; Shindo, T; Shioya, T; Watanabe, A, 1998)
"In order to clarify the mechanism of the antitussive effects of azelastine hydrochloride (azelastine, CAS 790307-93-0), the cough responses to inhaled capsaicin and substance P (SP) were evaluated before and after the administration of azelastine in conscious guinea pigs."3.71Mechanism of the antitussive effect of azelastine in guinea pigs. ( Ito, N; Miura, M; Sano, M; Sasaki, M; Shioya, T; Watanabe, A, 2002)
"Rhinosinusitis was assessed by questionnaires, direct examination of the nose and by high-resolution computed tomography."1.35Postnasal drip and chronic cough: An open interventional study. ( Arbery, J; Chung, KF; Durham, SR; Macedo, P; MacKay, I; Saleh, H; Torrego, A, 2009)
"The cough was relieved by inhaled procaterol in 10 patients (Group 2) but not in the other 10 patients (Group 1)."1.28Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyperresponsiveness. ( Fujimura, M; Matsuda, T; Sakamoto, S, 1992)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Singh, U1
Bernstein, JA1
Lorentz, H1
Sadoway, T1
Nelson, V1
Patel, P1
Salapatek, AM1
Fujimura, M2
Macedo, P1
Saleh, H1
Torrego, A1
Arbery, J1
MacKay, I1
Durham, SR1
Chung, KF1
Ito, N3
Shioya, T3
Watanabe, A2
Sano, M3
Sasaki, M2
Miura, M3
Kagaya, M2
Shindo, T2
Kashima, M1
Miura, S1
Kimura, K1
Sakamoto, S1
Matsuda, T1
Ohya, Y1
Kumamoto, K1
Fujishima, M1

Reviews

1 review available for azelastine and Cough

ArticleYear
[Causes of prolonged and chronic cough].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2008, Volume: 131, Issue:6

    Topics: Adrenergic beta-Agonists; Albuterol; Androstadienes; Asthma; Chronic Disease; Clenbuterol; Cough; Dr

2008

Trials

4 trials available for azelastine and Cough

ArticleYear
A Pilot Study Investigating Clinical Responses and Biological Pathways of Azelastine/Fluticasone in Nonallergic Vasomotor Rhinitis before and after Cold Dry Air Provocation.
    International archives of allergy and immunology, 2017, Volume: 173, Issue:3

    Topics: Adult; Air; Anti-Inflammatory Agents; Bronchial Provocation Tests; Cold Temperature; Cough; Female;

2017
Cough threshold for capsaicin increases by azelastine in patients with cough-variant asthma.
    Pulmonary pharmacology, 1996, Volume: 9, Issue:1

    Topics: Adult; Aged; Asthma; Bronchodilator Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Fema

1996
Antitussive effect of azelastine hydrochloride in patients with bronchial asthma.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Bronchial Hyperreactivit

1998
Effects of crossover application of sulindac and azelastine on enalapril-induced cough.
    Journal of human hypertension, 1992, Volume: 6, Issue:1

    Topics: Adult; Aged; Bronchodilator Agents; Cough; Enalapril; Female; Humans; Male; Middle Aged; Phthalazine

1992

Other Studies

3 other studies available for azelastine and Cough

ArticleYear
Postnasal drip and chronic cough: An open interventional study.
    Respiratory medicine, 2009, Volume: 103, Issue:11

    Topics: Administration, Intranasal; Adolescent; Adult; Aged; Androstadienes; Anti-Inflammatory Agents, Non-S

2009
Mechanism of the antitussive effect of azelastine in guinea pigs.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:6

    Topics: Animals; Antitussive Agents; Bronchoalveolar Lavage Fluid; Capsaicin; Cough; Female; Guinea Pigs; Ph

2002
Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyperresponsiveness.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Aged; Bronchi; Bronchodilator Agents; Cough; Drug Resistance; Ethan

1992