atipamezole has been researched along with Ache in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (57.14) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cahill, CM; Grenier, P; Jhamandas, K; Milne, B; Sutak, M | 1 |
| Cahill, CM; Jhamandas, K; Milne, B; Sutak, M | 1 |
| Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T | 1 |
| Kalso, EA; Kambur, O; Lilius, TO; Rauhala, PV; Rossi, SM; Väänänen, AJ | 1 |
| Eger, EI; Laster, MJ; Sonner, JM; Xing, Y | 1 |
| Chambers, JP; Lizarraga, I | 1 |
| Haapalinna, A; Pertovaara, A; Sirviö, J; Virtanen, R | 1 |
| Pertovaara, A; Wei, H | 3 |
| Chambers, JP; Livingston, A; Waterman, AE | 1 |
| Ozaki, GT; Penning, JP; Sabbe, MB; Yaksh, TL | 1 |
| Carlson, S; Hämäläinen, MM; Kauppila, T; Mecke, E; Pertovaara, A | 1 |
| Bravo, R; Herdegen, T; Pertovaara, A | 1 |
| Hämäläinen, MM; Pertovaara, A | 1 |
| Hao, JX; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Hämäläinen, MM; Jyväsjärvi, E; Kauppila, T; Pertovaara, A | 1 |
| Muir, WW; Skarda, RT | 1 |
| Guo, TZ; Kingery, WS; Maze, M; Poree, LR | 1 |
| Kalso, E; Kontinen, VK; Xu, M | 1 |
| Kauppila, T; Kemppainen, P; Pertovaara, A | 1 |
1 review(s) available for atipamezole and Ache
| Article | Year |
|---|---|
Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Central Nervous System Agents; Cognition Disorders; Emotions; Epilepsy; Humans; Imidazoles; Pain; Parkinson Disease; Receptors, Adrenergic, alpha-2; Sexual Behavior | 2005 |
1 trial(s) available for atipamezole and Ache
| Article | Year |
|---|---|
Involvement of opioidergic and alpha2-adrenergic mechanisms in the central analgesic effects of non-steroidal anti-inflammatory drugs in sheep.
Topics: Adrenergic alpha-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Female; Imidazoles; Injections, Intravenous; Injections, Spinal; Ketoprofen; Naloxone; Narcotic Antagonists; ortho-Aminobenzoates; Pain; Phenylbutazone; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Salicylic Acid; Sheep | 2006 |
19 other study(ies) available for atipamezole and Ache
| Article | Year |
|---|---|
Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesia; Analgesics; Animals; Clonidine; Drug Tolerance; Imidazoles; Injections, Spinal; Male; Morphine; Norepinephrine; Pain; Pain Management; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic | 2014 |
Low dose alpha-2 antagonist paradoxically enhances rat norepinephrine and clonidine analgesia.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesia; Analgesics; Animals; Clonidine; Drug Synergism; Imidazoles; Male; Norepinephrine; Pain; Rats; Rats, Sprague-Dawley | 2011 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine | 2011 |
Intrathecal atipamezole augments the antinociceptive effect of morphine in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Hot Temperature; Imidazoles; Injections, Spinal; Injections, Subcutaneous; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Pressure; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Alpha-2 adrenoreceptors probably do not mediate the immobility produced by inhaled anesthetics.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Imidazoles; Isoflurane; Male; Movement; Pain; Physical Stimulation; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 2003 |
5-HT(1A) receptors in endogenous regulation of neuropathic hypersensitivity in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Imidazoles; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Spinal Nerves | 2006 |
Spinal and pontine alpha2-adrenoceptors have opposite effects on pain-related behavior in the neuropathic rat.
Topics: Adrenergic alpha-Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Imidazoles; Injections, Intraventricular; Injections, Spinal; Male; Microinjections; Neural Inhibition; Pain; Pain Measurement; Pain Threshold; Pons; Rats; Rats, Wistar; Reaction Time; Receptors, Adrenergic, alpha-2; Spinal Cord; Spinal Cord Injuries; Spinal Nerves; Time Factors; Touch | 2006 |
The effects of opioid and alpha 2 adrenergic blockade on non-steroidal anti-inflammatory drug analgesia in sheep.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Dipyrone; Double-Blind Method; Drug Interactions; Female; Foot Rot; Imidazoles; Injections, Intravenous; Lameness, Animal; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Random Allocation; Sheep; Sheep Diseases; Thromboxane B2 | 1995 |
Spinal and systemic action of the alpha 2 receptor agonist dexmedetomidine in dogs. Antinociception and carbon dioxide response.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia, Epidural; Anesthesia, Spinal; Animals; Body Temperature; Carbon Dioxide; Dogs; Dose-Response Relationship, Drug; Forelimb; Heart Rate; Hindlimb; Imidazoles; Infusions, Intravenous; Infusions, Parenteral; Medetomidine; Motor Activity; Naloxone; Pain; Receptors, Adrenergic, alpha-2; Respiration | 1994 |
Dissociation of the alpha 2-adrenergic antinociception from sedation following microinjection of medetomidine into the locus coeruleus in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Decerebrate State; Formaldehyde; Hypnotics and Sedatives; Imidazoles; Locus Coeruleus; Male; Medetomidine; Microinjections; Motor Activity; Pain; Pain Measurement; Rats; Rats, Wistar; Spinal Cord | 1994 |
Induction and suppression of immediate-early genes in the rat brain by a selective alpha-2-adrenoceptor agonist and antagonist following noxious peripheral stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, fos; Genes, jun; Imidazoles; Immediate-Early Proteins; Male; Medetomidine; Pain; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Spinal Cord; Thalamus; Transcription Factors | 1993 |
The rostroventromedial medulla is not involved in alpha 2-adrenoceptor-mediated antinociception in the rat.
Topics: Analysis of Variance; Animals; Cerebellum; Clonidine; Dose-Response Relationship, Drug; Hot Temperature; Imidazoles; Lidocaine; Male; Medetomidine; Medulla Oblongata; Microinjections; Pain; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex; Skin Temperature; Spinal Cord; Time Factors | 1993 |
Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-2 Receptor Antagonists; Analysis of Variance; Animals; Bicuculline; Electromyography; Electroshock; Female; GABA-A Receptor Antagonists; Imidazoles; Injections, Spinal; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Nerve Fibers; Nociceptin; Opioid Peptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord; Sural Nerve | 1996 |
Peripherally administered alpha2-adrenoceptor agonist in the modulation of chronic allodynia induced by spinal nerve ligation in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Imidazoles; Ligation; Male; Medetomidine; Pain; Pain Measurement; Rats; Rats, Wistar; Spinal Nerves | 1997 |
The effect of a selective alpha2-adrenoceptor antagonist on pain behavior of the rat varies, depending on experimental parameters.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electrophysiology; Formaldehyde; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Imidazoles; Male; Narcotic Antagonists; Neurons; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid; Reflex; Spinal Cord | 1998 |
Influence of atipamezole on effects of midsacral subarachnoidally administered detomidine in mares.
Topics: Acid-Base Equilibrium; Adrenergic alpha-Antagonists; Analgesics; Animals; Blood Pressure; Body Temperature; Cross-Over Studies; Drug Interactions; Electric Stimulation; Female; Heart Rate; Horses; Imidazoles; Pain; Random Allocation; Respiration; Sacrum; Sensation; Single-Blind Method; Subarachnoid Space | 1998 |
The analgesic potency of dexmedetomidine is enhanced after nerve injury: a possible role for peripheral alpha2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Male; Medetomidine; Pain; Pain Threshold; Quinolizines; Rats; Rats, Sprague-Dawley; Spinal Nerves | 1998 |
Endogenous noradrenergic tone controls symptoms of allodynia in the spinal nerve ligation model of neuropathic pain.
Topics: Adrenergic alpha-Antagonists; Animals; Disease Models, Animal; Imidazoles; Ligation; Male; Naloxone; Narcotic Antagonists; Norepinephrine; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Sodium Chloride; Spinal Nerves | 1999 |
The effects of medetomidine, an alpha-2-adrenoceptor agonist, and cocaine on the tooth pulp-evoked jaw-opening reflex in cat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Cats; Cocaine; Dental Pulp; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Imidazoles; Jaw; Medetomidine; Pain; Reflex | 1991 |