aspirin has been researched along with Cough in 37 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of a single, high dose of aspirin has been assessed against low chloride cough challenge." | 9.07 | The low-chloride cough response is not inhibited by a single, high dose of aspirin. ( Barnes, PJ; Fuller, RW; Stone, RA, 1992) |
| "Controlled clinical research has been carried out on the activity and tolerance of a new active principle, guacetisal (Broncaspin) obtained from the esterification of acetylsalicylic acid with guaiacol, in the treatment of chronic bronchitis." | 9.05 | [Controlled clinical study of the treatment of chronic bronchitis with guacetisal]. ( Caltagirone, S; Crimi, N; Cusmano, F; Di Maria, GU; Palermo, F; Vagliasindi, M, 1981) |
| " All of them concomitantly received 100 mg/day aspirin because of previous ischaemic heart disease and presented similar clinical features: sudden onset of abdominal pain during a severe cough episode due to bronchial infection." | 7.73 | Prophylaxis with enoxaparin can produce a giant abdominal wall haematoma when associated with low doses of aspirin among elderly patients suffering cough attacks. ( Gonzalez-Ordonez, AJ; Macías-Robles, MD; Peliz, MG, 2005) |
| "This self-matched control study aimed to compare the efficiency of two different regimens of active treatment: aspirin in low (100 mg daily) versus intermediate (500 mg daily) doses in abolishing angiotensin-converting enzyme inhibitor (ACEI)-induced cough." | 7.70 | Intermediate but not low doses of aspirin can suppress angiotensin-converting enzyme inhibitor-induced cough. ( Fisman, EZ; Grossman, E; Motro, M; Nosrati, I; Shemesh, J; Tenenbaum, A, 2000) |
| "Guacetisal was administered to a group of patients suffering from chronic asthmatic bronchitis." | 7.66 | [Clinico-functional data concerning chronic asthmatic bronchitis patients treated wih guacetisal]. ( Bande, G; Coghe, M; Meloni, M; Nonne, G, 1981) |
| "The effect of a single, high dose of aspirin has been assessed against low chloride cough challenge." | 5.07 | The low-chloride cough response is not inhibited by a single, high dose of aspirin. ( Barnes, PJ; Fuller, RW; Stone, RA, 1992) |
| "Controlled clinical research has been carried out on the activity and tolerance of a new active principle, guacetisal (Broncaspin) obtained from the esterification of acetylsalicylic acid with guaiacol, in the treatment of chronic bronchitis." | 5.05 | [Controlled clinical study of the treatment of chronic bronchitis with guacetisal]. ( Caltagirone, S; Crimi, N; Cusmano, F; Di Maria, GU; Palermo, F; Vagliasindi, M, 1981) |
| " New pharmaceutical compounds such as renin inhibitors, angiotensin II receptor antagonists and aldosterone antagonists are bringing new insights not only into the importance of different components of the renin-angiotensin-aldosterone system in heart failure but also into the mode of action of angiotensin-converting enzyme inhibitors." | 4.79 | Inhibition of the renin-angiotensin-aldosterone system in heart failure: new insights from basic clinical research. ( Cleland, JG; Morgan, K, 1996) |
| " All of them concomitantly received 100 mg/day aspirin because of previous ischaemic heart disease and presented similar clinical features: sudden onset of abdominal pain during a severe cough episode due to bronchial infection." | 3.73 | Prophylaxis with enoxaparin can produce a giant abdominal wall haematoma when associated with low doses of aspirin among elderly patients suffering cough attacks. ( Gonzalez-Ordonez, AJ; Macías-Robles, MD; Peliz, MG, 2005) |
| "Between 8-20 percent of adult asthmatics experience bronchospasm following ingestion of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs)." | 3.70 | NSAID-induced bronchospasm--a common and serious problem. A report from MEDSAFE, the New Zealand Medicines and Medical Devices Safety Authority. ( Sturtevant, J, 1999) |
| "This self-matched control study aimed to compare the efficiency of two different regimens of active treatment: aspirin in low (100 mg daily) versus intermediate (500 mg daily) doses in abolishing angiotensin-converting enzyme inhibitor (ACEI)-induced cough." | 3.70 | Intermediate but not low doses of aspirin can suppress angiotensin-converting enzyme inhibitor-induced cough. ( Fisman, EZ; Grossman, E; Motro, M; Nosrati, I; Shemesh, J; Tenenbaum, A, 2000) |
| "Methacholine provocation test, bronchial reversibility test, aspirin inhalation test, and cough provocation test have been performed at our institute to examine pathophysiology and to diagnose bronchial diseases." | 3.68 | [Bronchial provocation test in bronchial asthma]. ( Fujimura, M; Hashimoto, T; Kamio, Y, 1993) |
| "Guacetisal was administered to a group of patients suffering from chronic asthmatic bronchitis." | 3.66 | [Clinico-functional data concerning chronic asthmatic bronchitis patients treated wih guacetisal]. ( Bande, G; Coghe, M; Meloni, M; Nonne, G, 1981) |
| "Reports of drug-induced pulmonary disease from other countries are also reviewed." | 2.38 | Drug-induced pulmonary disease. ( Bryant, DH, 1992) |
| "Prednisolone was initiated with clinical and analytical improvement." | 1.56 | Boundaries of a systemic disease: a protean presentation of giant cell arteritis. ( Brotas, V; Camara, L; Mesquita, A; Patrício, C, 2020) |
| "Rectus sheath hematoma is a rare and often misdiagnosed clinical condition." | 1.42 | Rectus sheath hematoma due to cough in an elderly patient under antiplatelet therapy. ( Çetin, M; Çoşğun, IG; Ünal, Y, 2015) |
| "A dry bothersome cough is the most common adverse class effect of all angiotensin-converting enzyme inhibitors (ACE-I)." | 1.31 | The combined cough frequency/severity scoring: a new approach to cough evaluation in clinical settings. ( Fisman, EZ; Motro, M; Pines, A; Shapira, I; Tenenbaum, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (37.84) | 18.7374 |
| 1990's | 8 (21.62) | 18.2507 |
| 2000's | 8 (21.62) | 29.6817 |
| 2010's | 3 (8.11) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Mesquita, A | 1 |
| Camara, L | 1 |
| Patrício, C | 1 |
| Brotas, V | 1 |
| Alay, H | 1 |
| Can, FK | 1 |
| Gözgeç, E | 1 |
| Kofman, AD | 1 |
| Sizemore, EK | 1 |
| Detelich, JF | 1 |
| Albrecht, B | 1 |
| Piantadosi, AL | 1 |
| Cattalini, M | 1 |
| Della Paolera, S | 1 |
| Zunica, F | 1 |
| Bracaglia, C | 1 |
| Giangreco, M | 1 |
| Verdoni, L | 1 |
| Meini, A | 1 |
| Sottile, R | 1 |
| Caorsi, R | 1 |
| Zuccotti, G | 1 |
| Fabi, M | 1 |
| Montin, D | 1 |
| Meneghel, A | 1 |
| Consolaro, A | 1 |
| Dellepiane, RM | 1 |
| Maggio, MC | 1 |
| La Torre, F | 1 |
| Marchesi, A | 1 |
| Simonini, G | 1 |
| Villani, A | 1 |
| Cimaz, R | 1 |
| Ravelli, A | 1 |
| Taddio, A | 1 |
| Çoşğun, IG | 1 |
| Ünal, Y | 1 |
| Çetin, M | 1 |
| Einecke, U | 1 |
| Wandeler-Meyer, K | 1 |
| Bremerich, J | 1 |
| Christ, M | 1 |
| Guirguis-Blake, J | 1 |
| Wepner, U | 1 |
| Macchia, L | 1 |
| Caiaffa, MF | 1 |
| Vacca, A | 1 |
| Tursi, A | 1 |
| CARTER, CH | 1 |
| Macías-Robles, MD | 1 |
| Peliz, MG | 1 |
| Gonzalez-Ordonez, AJ | 1 |
| Perdreau, A | 1 |
| Reginster, P | 1 |
| Bartolucci, L | 1 |
| Canini, F | 1 |
| Fioroni, E | 1 |
| Pinchi, G | 1 |
| Carosi, M | 1 |
| Caltagirone, S | 1 |
| Vagliasindi, M | 1 |
| Palermo, F | 1 |
| Di Maria, GU | 1 |
| Crimi, N | 1 |
| Cusmano, F | 1 |
| Lappa, B | 1 |
| Di Caterina, N | 1 |
| Perna, A | 1 |
| Di Fraia, C | 1 |
| Verdoliva, A | 1 |
| Margarita, A | 1 |
| Lauri, D | 1 |
| Salvini, P | 1 |
| Marvulli, G | 1 |
| Partipilo, N | 1 |
| Mora, P | 1 |
| Levi, P | 1 |
| Marostica, G | 1 |
| Pelucco, D | 1 |
| Bernabò Di Negro, G | 1 |
| Ravazzoni, C | 1 |
| Rubegni, M | 1 |
| De Mauro, G | 1 |
| Zanierato, G | 1 |
| Ranghino, E | 1 |
| Negri, L | 1 |
| Morandini, GC | 1 |
| Zuccali, G | 1 |
| Gherson, G | 1 |
| Parenti, M | 1 |
| Bande, G | 1 |
| Coghe, M | 1 |
| Meloni, M | 1 |
| Nonne, G | 1 |
| Imokawa, S | 1 |
| Sato, A | 1 |
| Taniguchi, M | 1 |
| Toyoshima, M | 1 |
| Nakazawa, K | 1 |
| Hayakawa, H | 1 |
| Chida, K | 1 |
| Fujimura, M | 1 |
| Kamio, Y | 1 |
| Hashimoto, T | 1 |
| Cupp, MJ | 1 |
| Moherman, LJ | 1 |
| Cleland, JG | 1 |
| Morgan, K | 1 |
| Gorton, B | 1 |
| Sturtevant, J | 1 |
| Tenenbaum, A | 3 |
| Grossman, E | 2 |
| Shemesh, J | 1 |
| Fisman, EZ | 3 |
| Nosrati, I | 1 |
| Motro, M | 3 |
| Shapira, I | 1 |
| Pines, A | 1 |
| Stone, RA | 1 |
| Barnes, PJ | 1 |
| Fuller, RW | 1 |
| Bryant, DH | 1 |
| Lernhardt, EB | 1 |
| Ziegler, MG | 1 |
| Chafee, FH | 1 |
| Settipane, GA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Topical Bupivacaine Effect On The Response To Awake Extubation During Emergence From General Anesthesia In Patients Undergoing Elective Thyroidectomy. A Randomized Controlled Study[NCT04471597] | 48 participants (Actual) | Interventional | 2020-07-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for aspirin and Cough
| Article | Year |
|---|---|
Adding ACE inhibitors or ARBs to standard therapy for stable ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting En | 2012 |
Inhibition of the renin-angiotensin-aldosterone system in heart failure: new insights from basic clinical research.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; | 1996 |
Drug-induced pulmonary disease.
Topics: Adrenergic beta-Antagonists; Adverse Drug Reaction Reporting Systems; Aerosols; Amiodarone; Angioten | 1992 |
12 trials available for aspirin and Cough
| Article | Year |
|---|---|
[Clinical evaluation of the therapeutic effectiveness of a new drug with anti-inflammatory-balsamic action, guacetisal, in respiratory tract diseases].
Topics: Adolescent; Adult; Aged; Aspirin; Bronchitis; Bronchopneumonia; Chronic Disease; Clinical Trials as | 1981 |
[Controlled clinical study of the treatment of chronic bronchitis with guacetisal].
Topics: Adult; Aged; Aspirin; Bromhexine; Bronchitis; Chronic Disease; Clinical Trials as Topic; Cough; Fema | 1981 |
[Clinico-functional observations on the use of guacetisal in the treatment of chronic obstructive bronchopneumopathy].
Topics: Adult; Aged; Aspirin; Bronchitis; Clinical Trials as Topic; Cough; Humans; Lung Diseases, Obstructiv | 1981 |
[Clinical evaluation of the activity of 2 preparations with similar action in bronchopneumopathies in the aged].
Topics: Aged; Aminopyrine; Aspirin; Blood; Bronchitis; Clinical Trials as Topic; Cough; Drug Combinations; D | 1981 |
[Preliminary study of guacetisal in chronic bronchitis].
Topics: Aged; Aspirin; Bronchitis; Chronic Disease; Clinical Trials as Topic; Cough; Dyspnea; Humans; Male; | 1981 |
[Broncaspin in respiratory diseases in pediatrics. Clinical contribution].
Topics: Aspirin; Bronchitis; Bronchopneumonia; Child; Child, Preschool; Clinical Trials as Topic; Cough; Dys | 1981 |
[The use of B.I. 1070/P (guacetisal) in inflammatory bronchopneumopathies in the acute phase].
Topics: Acute Disease; Adolescent; Adult; Aged; Aspirin; Blood; Bronchitis; Bronchopneumonia; Clinical Trial | 1981 |
[Clinical study of a preparation with bronchomucotropic activity: guacetisal].
Topics: Aged; Aspirin; Bronchitis; Clinical Trials as Topic; Cough; Female; Humans; Lung Diseases, Obstructi | 1981 |
[Treatment of bronchial inflammatory disorders with guacetisal].
Topics: Acute Disease; Aspirin; Bromhexine; Bronchitis; Carbonates; Chronic Disease; Clinical Trials as Topi | 1981 |
[Clinical trials of a new preparation in chronic bronchopneumopathies].
Topics: Adult; Aged; Aspirin; Asthma; Bronchitis; Chronic Disease; Clinical Trials as Topic; Cough; Female; | 1981 |
Lessons from low enrollment in ACE inhibitor cough study.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cough; D | 1996 |
The low-chloride cough response is not inhibited by a single, high dose of aspirin.
Topics: Aspirin; Bicarbonates; Chlorides; Cough; Double-Blind Method; Humans; Sodium; Sodium Bicarbonate | 1992 |
22 other studies available for aspirin and Cough
| Article | Year |
|---|---|
Boundaries of a systemic disease: a protean presentation of giant cell arteritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cholestasis; Cough; Diagnosis, Differential; Drug | 2020 |
Cerebral Infarction in an Elderly Patient with Coronavirus Disease.
Topics: Aged, 80 and over; Anticoagulants; Aspirin; Betacoronavirus; Cerebral Infarction; Coronavirus; Coron | 2020 |
A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)-like illness: a case report.
Topics: Adult; Aspirin; Betacoronavirus; Coronavirus Infections; Cough; COVID-19; COVID-19 Drug Treatment; D | 2020 |
Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in Italy: results from a national, multicenter survey.
Topics: Age Distribution; Antirheumatic Agents; Aspirin; C-Reactive Protein; Child; Child, Preschool; Corona | 2021 |
Rectus sheath hematoma due to cough in an elderly patient under antiplatelet therapy.
Topics: Abdomen, Acute; Aged, 80 and over; Aspirin; Cough; Female; Hematoma; Humans; Platelet Aggregation In | 2015 |
[From wheezing to anaphylactic shock: allergology for your practice].
Topics: Adult; Allergy and Immunology; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2008 |
[Abdominal tumor after persistent coughing and uncontrolled anticoagulation].
Topics: Abdomen, Acute; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coloni | 2010 |
[A case for proton pump blocker... When cough comes from the stomach].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antirheumatic Age | 2002 |
General adverse reaction to aspirin administered by transdermal iontophoresis.
Topics: Administration, Cutaneous; Adolescent; Analgesics; Angioedema; Aspirin; Cough; Dyspnea; Erythema; Hu | 2002 |
A clinical evaluation of the effectiveness of Novrad and acetylsalicylic acid in children with cough.
Topics: Antitussive Agents; Aspirin; Child; Cough; Humans | 1963 |
Prophylaxis with enoxaparin can produce a giant abdominal wall haematoma when associated with low doses of aspirin among elderly patients suffering cough attacks.
Topics: Abdominal Wall; Aged; Aged, 80 and over; Aspirin; Cough; Dose-Response Relationship, Drug; Drug Ther | 2005 |
[Clinical case of the month. Computerized tomographic diagnosis of hematoma of the rectus abdominis muscle].
Topics: Abdominal Pain; Aged, 80 and over; Aspirin; Cough; Diagnosis, Differential; Hematoma; Humans; Male; | 2007 |
[Clinico-functional data concerning chronic asthmatic bronchitis patients treated wih guacetisal].
Topics: Adult; Aged; Aspirin; Bronchial Spasm; Bronchitis; Cough; Dyspnea; Female; Humans; Male; Middle Aged | 1981 |
[A case of aspirin-induced cough without bronchoconstriction. A new type of aspirin hypersensitivity].
Topics: Aspirin; Bronchoconstriction; Cough; Drug Hypersensitivity; Female; Humans; Middle Aged | 1994 |
[Bronchial provocation test in bronchial asthma].
Topics: Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cough; Humans; Methacholine | 1993 |
Advice on medications for coughs and colds.
Topics: Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child, Preschool; Common Col | 1997 |
NSAID-induced bronchospasm--a common and serious problem. A report from MEDSAFE, the New Zealand Medicines and Medical Devices Safety Authority.
Topics: Adult; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Chroni | 1999 |
Intermediate but not low doses of aspirin can suppress angiotensin-converting enzyme inhibitor-induced cough.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Diseases; Cough; Dose-Respon | 2000 |
The combined cough frequency/severity scoring: a new approach to cough evaluation in clinical settings.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cough; Female; Humans; Hypertension; Male; | 2001 |
Clinical evidence of dose-dependent interaction between aspirin and angiotensin-converting enzyme inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Diseases; Cough; Cyclooxygenase In | 2002 |
Cough caused by cilazapril.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cilazapril; Cough; Female; Humans; M | 1988 |
Asthma caused by FD&C approved dyes.
Topics: Acetaminophen; Adult; Angioedema; Aspirin; Asthma; Benzoates; Coloring Agents; Cough; Diethylstilbes | 1967 |