apnea and Hypercapnia
apnea has been researched along with Hypercapnia in 153 studies
Apnea: A transient absence of spontaneous respiration.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " It was hypothesized that HCVR is decreased by repeated breath hold maximal efforts (RBHE) before and after apnea training in comparison with no training and the control condition." | 9.20 | Repeated apneas and hypercapnic ventilatory response before and after apnea training. ( Bourdas, DI; Geladas, ND; Pavlakis, KI; Triantafillou, DV; Tsakiris, TS, 2015) |
| "Obstructive sleep apnea is associated with sustained elevation of muscle sympathetic nerve activity (MSNA) and altered chemoreflex control of MSNA, both of which likely play an important role in the development of hypertension in these patients." | 9.11 | Periods of intermittent hypoxic apnea can alter chemoreflex control of sympathetic nerve activity in humans. ( Burk, JR; Cutler, MJ; Keller, DM; Smith, ML; Swift, NM; Wasmund, WL, 2004) |
| "According to current guidelines, apnea testing has to be performed after prerequisites have been met and in a fashion where hypercapnia is achieved in the face of stable oxygenation and hemodynamics." | 8.91 | Apnea testing on extracorporeal membrane oxygenation: Case report and literature review. ( Lazaridis, C; Shah, V, 2015) |
| "Apnea of prematurity (AOP) is a significant clinical problem manifested by an unstable respiratory rhythm reflecting the immaturity of respiratory control systems." | 8.87 | Apnea of prematurity: pathogenesis and management strategies. ( Mathew, OP, 2011) |
| "Prolonged apnea is characterized by hypoxia/hypercapnia." | 8.12 | Changes in hormones after apneic hypoxia/hypercapnia - An investigation in voluntary apnea divers. ( Dolscheid-Pommerich, RC; Eichhorn, L; Fimmers, R; Stoffel-Wagner, B, 2022) |
| "Voluntary asphyxia imposed by static apnea challenges blood-brain barrier (BBB) integrity in humans through transient extremes of hypertension, hypoxemia and hypercapnia." | 8.12 | Hypoxemia increases blood-brain barrier permeability during extreme apnea in humans. ( Ainslie, PN; Bailey, DM; Bain, AR; Barak, OF; Drvis, I; Dujic, Z; Hirtz, C; Hoiland, RL; Janigro, D; Lehmann, S; MacLeod, DB; Marchi, N, 2022) |
| " There is evidence that future SIDS cases experience more apnea and have abnormal arousal from sleep." | 7.85 | Active sleep unmasks apnea and delayed arousal in infant rat pups lacking central serotonin. ( Cummings, KJ; Geurts, A; Hodges, MR; Young, JO, 2017) |
| "Gaseous mixing in the anatomical deadspace with stimulation of respiratory ventilation through cardiogenic oscillations is an important physiological mechanism at the onset of apnea, which has been credited with various beneficial effects, e." | 7.85 | Investigating the effect of cardiac oscillations and deadspace gas mixing during apnea using computer simulation. ( Bates, DG; Chikhani, M; Das, A; Hardman, JG; Laviola, M, 2017) |
| " PRKO mice exhibited similar levels of minute ventilation during non-REM and REM sleep, and higher frequencies of sighs and post-sigh apneas during non-REM sleep compared to WT." | 7.80 | The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice. ( Boukari, R; Joseph, V; Laouafa, S; Lavoie, R; Marcouiller, F, 2014) |
| "We have examined influence of hypocapnia, mild hypercapnia and hypoxia on the durations of fictive apnea and respiratory disruption elicited by injection of 0." | 7.79 | Laryngeal reflex apnea in neonates: effects of CO2 and the complex influence of hypoxia. ( Bartlett, D; Leiter, JC; Xia, L, 2013) |
| "Recurrent apneas are important causes of hospitalization and morbidity in newborns." | 7.79 | Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat. ( Bairam, A; Caravagna, C; Fournier, S; Gulemetova, R; Julien, C; Kinkead, R; Soliz, J; Steele, S, 2013) |
| "Haemoglobin increased by 4% after apneas in the 'Hypercapnia' trial (P = 0." | 7.78 | Effect of hypercapnia on spleen-related haemoglobin increase during apnea. ( Engan, HK; Lodin-Sundström, A; Richardson, MX; Schagatay, E, 2012) |
| " These results suggest that an increase in the cerebral blood volume observed during the struggle phase of dry apnea is most likely caused by the IBM at the time of the hypercapnia-induced cerebral vasodilatation and peripheral vasoconstriction." | 7.75 | Involuntary breathing movements improve cerebral oxygenation during apnea struggle phase in elite divers. ( Breskovic, T; Dujic, Z; Heusser, K; Ljubkovic, M; Marinovic, J; Palada, I; Uglesic, L; Valic, Z, 2009) |
| " The aim of the present study was to elucidate whether also short-term apnea training (repeating apneas with short intervals) reduces the HCVR, thereby being one contributing factor explaining the progressively increasing breath-holding time (BHT) with repetition of apneas." | 7.75 | Repeated apneas do not affect the hypercapnic ventilatory response in the short term. ( Andersson, JP; Schagatay, E, 2009) |
| " We now report on the temporal relationship between ictal apnea and seizure onset and spread in patients undergoing video-EEG (electroencephalography) telemetry (VET) with intracranial electrodes." | 7.75 | Ictal apnea linked to contralateral spread of temporal lobe seizures: Intracranial EEG recordings in refractory temporal lobe epilepsy. ( Bateman, LM; Seyal, M, 2009) |
| "Although apnea is common in premature babies, there is a paucity of information concerning the pathophysiologic basis of these episodes and their relationship to other perinatal conditions such as hyperbilirubinemia." | 7.74 | Hyperbilirubinemia diminishes respiratory drive in a rat pup model. ( Haxhiu, MA; Iben, SC; Martin, RJ; Mayer, CA; Mesner, O; Miller, MJ; Prabha, KC, 2008) |
| "Caffeine is an adenosine receptor antagonist commonly used as a respiratory stimulant to treat neonatal apneas of premature newborn." | 7.73 | Long-term consequences of neonatal caffeine on ventilation, occurrence of apneas, and hypercapnic chemoreflex in male and female rats. ( Bairam, A; Kinkead, R; Montandon, G, 2006) |
| "Obstructive sleep apnea (OSA) is associated with transient elevation of muscle sympathetic nerve activity (MSNA) during apneic events, which often produces elevated daytime MSNA in OSA patients." | 7.72 | Hypoxia-mediated prolonged elevation of sympathetic nerve activity after periods of intermittent hypoxic apnea. ( Cutler, MJ; Keller, DM; Smith, ML; Swift, NM; Wasmund, WL, 2004) |
| "The effects of hypoxemia and hypercapnia in acute cardiovascular response to periodic non-obstructive apneas were explored in seven preinstrumented, sedated paralyzed and ventilated pigs under three conditions: room air breathing (RA), O2 supplementation (O2), and supplementation with O2 and CO2 (CO2)." | 7.70 | Role of hypoxemia and hypercapnia in acute cardiovascular response to periodic apneas in sedated pigs. ( Chen, L; Greenberg, H; Scharf, SM; Sica, AL, 1998) |
| "This study was carried out on seven chloralose-anesthetized sheep and was designed to investigate the role of muscular afferent fiber stimulation on the duration of reflex apnea triggered by laryngeal stimulation (LS)." | 7.69 | Laryngeal reflex apnea is blunted during and after hindlimb muscle contraction in sheep. ( Beyaert, C; Chalon, B; Gille, JP; Haouzi, P; Marchal, F, 1997) |
| "Arousal is an important protective mechanism that aids in the resolution of obstructive sleep apnea in adults and children, but its role in neonatal apnea has not been investigated." | 7.68 | Behavioral arousal in newborn infants and its association with termination of apnea. ( Belan, MA; Cowen, CP; Mathew, OP; Thoppil, CK, 1991) |
| "The effects of hypoxia and hypercapnea in the production of somatostatin (SRIF)-induced apnea were studied during rebreathing experiments." | 7.67 | Somatostatin-induced apnea: interaction with hypoxia and hypercapnea in the rat. ( Agnati, LF; Fuxe, K; Harfstrand, A; Kaijser, L; Kalia, M, 1984) |
| "We examined the clinical and respiratory physiologic characteristics of 18 patients in whom a diagnosis of central sleep apnea syndrome was established by overnight polysomnographic studies." | 7.67 | Clinical and physiologic heterogeneity of the central sleep apnea syndrome. ( Bradley, TD; McNicholas, WT; Phillipson, EA; Popkin, J; Rutherford, R; Zamel, N, 1986) |
| "Five series of breath-hold (BH) experiments were conducted on eight male subjects with the purpose of partitioning the effects of apnea per se, hypercapnia, and hypoxia on the development and maintenance of BH bradycardia." | 7.66 | Effects of hypercapnia, hypoxia, and rebreathing on heart rate response during apnea. ( Hong, SK; Lin, YC; Shida, KK, 1983) |
| " Fifty-eight percent of the observations with fetal apnea (FBM 0 to 9% in 2 hours) showed hypoxia (PaO2 less than or equal to 16 torr), whereas only 4% of the observations with FBM greater than 10% were associated with hypoxia." | 7.66 | Effect of oxygen and of carbon dioxide tension on the incidence of apnea in fetal lambs. ( Bissonnette, JM; Cronan, JZ; Hohimer, AR; Paul, MS, 1980) |
| "The present study was designed to investigate the effect of stimulus duration and chemosensory input on the recovery of central respiratory activity from apnea induced by superior laryngeal nerve (SLN) electrical stimulation." | 7.66 | Recovery from central apnea: effect of stimulus duration and end-tidal CO2 partial pressure. ( Lawson, EE, 1982) |
| "Twelve patients with predominantly obstructive type sleep apnea underwent cardiac catheterization, hemodynamic monitoring, and arterial blood gas analysis during wakefulness and sleep." | 7.65 | Hemodynamics in sleep-induced apnea. Studies during wakefulness and sleep. ( Dement, WC; Guilleminault, C; Lehrman, KL; Schroeder, JS; Simmons, FB; Tilkian, AG, 1976) |
| " It was hypothesized that HCVR is decreased by repeated breath hold maximal efforts (RBHE) before and after apnea training in comparison with no training and the control condition." | 5.20 | Repeated apneas and hypercapnic ventilatory response before and after apnea training. ( Bourdas, DI; Geladas, ND; Pavlakis, KI; Triantafillou, DV; Tsakiris, TS, 2015) |
| "Obstructive sleep apnea is associated with sustained elevation of muscle sympathetic nerve activity (MSNA) and altered chemoreflex control of MSNA, both of which likely play an important role in the development of hypertension in these patients." | 5.11 | Periods of intermittent hypoxic apnea can alter chemoreflex control of sympathetic nerve activity in humans. ( Burk, JR; Cutler, MJ; Keller, DM; Smith, ML; Swift, NM; Wasmund, WL, 2004) |
| " In 15 healthy subjects, we examined the effects of dobutamine on breathing, hemodynamics, and sympathetic nerve activity (measured using microneurography) during normoxia, isocapnic hypoxia (10% O2), posthypoxic maximal voluntary end-expiratory apnea, hyperoxic hypercapnia, and cold pressor test (CPT)." | 5.10 | Dobutamine potentiates arterial chemoreflex sensitivity in healthy normal humans. ( Ciarka, A; Godart, P; Kojonazarov, B; Naeije, R; Somers, VK; van de Borne, P; Velez-Roa, S, 2003) |
| "To assess effects of anesthesia and opioids, we studied 13 children with obstructive sleep apnea (OSA, age 4." | 5.10 | Effects of OSA, inhalational anesthesia, and fentanyl on the airway and ventilation of children. ( Hinder, M; McBrien, F; Stewart, P; Waters, KA; Wharton, S, 2002) |
| "According to current guidelines, apnea testing has to be performed after prerequisites have been met and in a fashion where hypercapnia is achieved in the face of stable oxygenation and hemodynamics." | 4.91 | Apnea testing on extracorporeal membrane oxygenation: Case report and literature review. ( Lazaridis, C; Shah, V, 2015) |
| "Apnea of prematurity (AOP) is a significant clinical problem manifested by an unstable respiratory rhythm reflecting the immaturity of respiratory control systems." | 4.87 | Apnea of prematurity: pathogenesis and management strategies. ( Mathew, OP, 2011) |
| " Although more controlled studies would be helpful, relatively clear-cut indications for the use of ventilatory stimulants exist for hypercapnic obesity-hypoventilation patients (medroxyprogesterone), myxedema (thyroid replacement), central apnea (acetazolamide), and periodic breathing in congestive heart failure (theophylline)." | 4.80 | Pharmacologic treatment of sleep-disordered breathing. ( Hudgel, DW; Thanakitcharu, S, 1998) |
| "Voluntary asphyxia imposed by static apnea challenges blood-brain barrier (BBB) integrity in humans through transient extremes of hypertension, hypoxemia and hypercapnia." | 4.12 | Hypoxemia increases blood-brain barrier permeability during extreme apnea in humans. ( Ainslie, PN; Bailey, DM; Bain, AR; Barak, OF; Drvis, I; Dujic, Z; Hirtz, C; Hoiland, RL; Janigro, D; Lehmann, S; MacLeod, DB; Marchi, N, 2022) |
| "Prolonged apnea is characterized by hypoxia/hypercapnia." | 4.12 | Changes in hormones after apneic hypoxia/hypercapnia - An investigation in voluntary apnea divers. ( Dolscheid-Pommerich, RC; Eichhorn, L; Fimmers, R; Stoffel-Wagner, B, 2022) |
| " Twenty-nine (85%) patients had sleep-related breathing disorders based on an Apnea-Hypopnea Index of ≥ 5/h." | 4.12 | Sleep-related hypoventilation and hypercapnia in multiple system atrophy detected by polysomnography with transcutaneous carbon dioxide monitoring. ( Araki, N; Hirano, S; Ikeda, S; Ito, S; Kasai, H; Koide, K; Koshikawa, K; Kuwabara, S; Shionoya, Y; Sugiyama, A; Terada, J; Wang, J; Yamamoto, T; Yamanaka, Y, 2022) |
| " The determination of brain death by clinical criteria requires apnea testing, which has historically been viewed as challenging in patients supported by ECMO." | 3.91 | Clinical Determination of Brain Death in Children Supported by Extracorporeal Membrane Oxygenation. ( Berger, JT; Carpenter, JL; Dean, NP; Harrar, DB; Kukreti, V, 2019) |
| " Consistent with this idea, IRt inhibition blocked rhythmic motor and autonomic components of fictive swallow but not swallow-related apnea." | 3.91 | Neurons in the Intermediate Reticular Nucleus Coordinate Postinspiratory Activity, Swallowing, and Respiratory-Sympathetic Coupling in the Rat. ( Hildreth, CM; Kumar, NN; Le, S; McMullan, S; Phillips, JK; Sun, QJ; Toor, RUAS, 2019) |
| "Gaseous mixing in the anatomical deadspace with stimulation of respiratory ventilation through cardiogenic oscillations is an important physiological mechanism at the onset of apnea, which has been credited with various beneficial effects, e." | 3.85 | Investigating the effect of cardiac oscillations and deadspace gas mixing during apnea using computer simulation. ( Bates, DG; Chikhani, M; Das, A; Hardman, JG; Laviola, M, 2017) |
| " There is evidence that future SIDS cases experience more apnea and have abnormal arousal from sleep." | 3.85 | Active sleep unmasks apnea and delayed arousal in infant rat pups lacking central serotonin. ( Cummings, KJ; Geurts, A; Hodges, MR; Young, JO, 2017) |
| "In case of apnea, arterial partial pressure of oxygen (pO2) decreases, while partial pressure of carbon dioxide (pCO2) increases." | 3.83 | A Model to Simulate Clinically Relevant Hypoxia in Humans. ( Böhnert, V; Eichhorn, L; Ellerkmann, RK; Erdfelder, F; Kessler, F; Meyer, R; Reckendorf, A, 2016) |
| " However, neonatal A1R(-/-) mice appeared to have more frequently periods of apnea during hypoxia and in the post-hypoxic control period." | 3.83 | The in vivo respiratory phenotype of the adenosine A1 receptor knockout mouse. ( Buehler, P; Georgieff, M; Heitzmann, D; Schweda, F; Thomas, J; Warth, R, 2016) |
| " PRKO mice exhibited similar levels of minute ventilation during non-REM and REM sleep, and higher frequencies of sighs and post-sigh apneas during non-REM sleep compared to WT." | 3.80 | The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice. ( Boukari, R; Joseph, V; Laouafa, S; Lavoie, R; Marcouiller, F, 2014) |
| " MSNA recordings were obtained through microneurography in LH and HH at baseline, during rebreathing causing progressive hypoxia and hypercapnia, and during a hypercapnic-hypoxic end-inspiratory apnea." | 3.79 | Hormone phase dependency of neural responses to chemoreflex-driven sympathoexcitation in young women using hormonal contraceptives. ( Gimon, TI; Luchyshyn, TA; Nielson, CA; Shoemaker, JK; Usselman, CW; Van Uum, SH, 2013) |
| "Recurrent apneas are important causes of hospitalization and morbidity in newborns." | 3.79 | Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat. ( Bairam, A; Caravagna, C; Fournier, S; Gulemetova, R; Julien, C; Kinkead, R; Soliz, J; Steele, S, 2013) |
| "We have examined influence of hypocapnia, mild hypercapnia and hypoxia on the durations of fictive apnea and respiratory disruption elicited by injection of 0." | 3.79 | Laryngeal reflex apnea in neonates: effects of CO2 and the complex influence of hypoxia. ( Bartlett, D; Leiter, JC; Xia, L, 2013) |
| " Forced vital capacity (FVC), maximum static pressure, voluntary apnea time, Epworth scale and arterial blood gases were measured." | 3.79 | [Analysis of factors associated with chronic hypercapnia in patients with myotonic dystrophy]. ( Aruj, PK; De Vito, EL; Monteiro, SG, 2013) |
| "Haemoglobin increased by 4% after apneas in the 'Hypercapnia' trial (P = 0." | 3.78 | Effect of hypercapnia on spleen-related haemoglobin increase during apnea. ( Engan, HK; Lodin-Sundström, A; Richardson, MX; Schagatay, E, 2012) |
| " Current management of ethanol-barbiturate-induced apnea is limited to ventilatory and circulatory support coupled with drug elimination." | 3.78 | Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717. ( Ding, X; Greer, JJ; Ren, J, 2012) |
| " While the endpoint of postswallow apnea correlated well to the endpoint of pharyngeal swallowing, duration of preswallow apnea was highly variable." | 3.76 | Breathing and swallowing in normal man--effects of changes in body position, bolus types, and respiratory drive. ( Bodén, K; Ekberg, O; Eriksson, LI; Hårdemark Cedborg, AI; Kuylenstierna, R; Sundman, E; Witt Hedström, H, 2010) |
| " The aim of the present study was to elucidate whether also short-term apnea training (repeating apneas with short intervals) reduces the HCVR, thereby being one contributing factor explaining the progressively increasing breath-holding time (BHT) with repetition of apneas." | 3.75 | Repeated apneas do not affect the hypercapnic ventilatory response in the short term. ( Andersson, JP; Schagatay, E, 2009) |
| " We then used a novel method that would allow accurate assessment of the ventilatory and heart rate responses to near square-wave challenges of hypoxia (10% O2), hypercapnia (5 and 8% CO2 in normoxia and hyperoxia), and asphyxia (8% CO2-10% O2), and to the induction of the Hering-Breuer inflation reflex (HBR), a potent, apnea-inducing reflex in newborns." | 3.75 | Severe spontaneous bradycardia associated with respiratory disruptions in rat pups with fewer brain stem 5-HT neurons. ( Commons, KG; Cummings, KJ; Fan, KC; Li, A; Nattie, EE, 2009) |
| " We now report on the temporal relationship between ictal apnea and seizure onset and spread in patients undergoing video-EEG (electroencephalography) telemetry (VET) with intracranial electrodes." | 3.75 | Ictal apnea linked to contralateral spread of temporal lobe seizures: Intracranial EEG recordings in refractory temporal lobe epilepsy. ( Bateman, LM; Seyal, M, 2009) |
| " These results suggest that an increase in the cerebral blood volume observed during the struggle phase of dry apnea is most likely caused by the IBM at the time of the hypercapnia-induced cerebral vasodilatation and peripheral vasoconstriction." | 3.75 | Involuntary breathing movements improve cerebral oxygenation during apnea struggle phase in elite divers. ( Breskovic, T; Dujic, Z; Heusser, K; Ljubkovic, M; Marinovic, J; Palada, I; Uglesic, L; Valic, Z, 2009) |
| "Repeated hypoxemia in obstructive sleep apnea patients increases sympathetic activity, thereby promoting arterial hypertension." | 3.74 | Central chemoreflex sensitivity and sympathetic neural outflow in elite breath-hold divers. ( Bakovic, D; Diedrich, A; Dujic, Z; Dzamonja, G; Heusser, K; Ivancev, V; Jordan, J; Joyner, MJ; Obad, A; Palada, I; Tank, J; Valic, Z, 2008) |
| "Although apnea is common in premature babies, there is a paucity of information concerning the pathophysiologic basis of these episodes and their relationship to other perinatal conditions such as hyperbilirubinemia." | 3.74 | Hyperbilirubinemia diminishes respiratory drive in a rat pup model. ( Haxhiu, MA; Iben, SC; Martin, RJ; Mayer, CA; Mesner, O; Miller, MJ; Prabha, KC, 2008) |
| " In 20 healthy male individuals with no sleep-related disorders, continuous recordings of blood velocity in the middle cerebral artery, arterial blood pressure, VE, end-tidal gases, and frontal cortical oxygenation using near infrared spectroscopy were monitored during hypercapnia (inspired CO(2), 5%), hypoxia [arterial O(2) saturation (Sa(O(2))) approximately 84%], and during a 20-s breath hold to investigate the related responses to hypercapnia, hypoxia, and apnea, respectively." | 3.74 | Morning attenuation in cerebrovascular CO2 reactivity in healthy humans is associated with a lowered cerebral oxygenation and an augmented ventilatory response to CO2. ( Ainslie, PN; Cummings, KJ; Swart, M, 2007) |
| "The aim of the present study was to investigate the effect of hypercapnia and hypoxia on apnea and nonnutritive swallowing (NNS) frequency, as well as on the coordination between NNS and phases of the respiratory cycle in newborn lambs, while taking into account the potential effects of states of alertness." | 3.74 | Effects of hypoxia and hypercapnia on nonnutritive swallowing in newborn lambs. ( Bournival, V; Duvareille, C; Lafrance, M; Langlois, C; Micheau, P; Pladys, P; Praud, JP; Samson, N; St-Hilaire, M, 2007) |
| " To examine the effects of severe hypoxic stress on the respiratory cycle, we exposed the strain with the highest or lowest hypoxic ventilatory response to 6% O(2) in N(2) until the onset of apnea." | 3.73 | Mice with blunted hypoxic ventilatory response are susceptible to respiratory disturbance during hypoxia. ( Adachi, T; Hida, W; Kikuchi, Y; Kitamuro, T; Ogawa, H; Okabe, S; Shibahara, S; Shirato, K, 2006) |
| "Caffeine is an adenosine receptor antagonist commonly used as a respiratory stimulant to treat neonatal apneas of premature newborn." | 3.73 | Long-term consequences of neonatal caffeine on ventilation, occurrence of apneas, and hypercapnic chemoreflex in male and female rats. ( Bairam, A; Kinkead, R; Montandon, G, 2006) |
| "Acute hypercapnia may develop during periodic breathing from an imbalance between abnormal ventilatory patterns during apnea and/or hypopnea and compensatory ventilatory response in the interevent periods." | 3.73 | Transition from acute to chronic hypercapnia in patients with periodic breathing: predictions from a computer model. ( Berger, KI; Charney, AN; Clain, JM; Goldring, RM; Norman, RG; Oppenheimer, BW; Rapoport, DM, 2006) |
| "Obstructive sleep apnea (OSA) is associated with transient elevation of muscle sympathetic nerve activity (MSNA) during apneic events, which often produces elevated daytime MSNA in OSA patients." | 3.72 | Hypoxia-mediated prolonged elevation of sympathetic nerve activity after periods of intermittent hypoxic apnea. ( Cutler, MJ; Keller, DM; Smith, ML; Swift, NM; Wasmund, WL, 2004) |
| " Tracheal contraction induced either by apnea, mechanical stimulation of the tracheal bifurcation or hypercapnia was always composed of tonic and rhythmic components." | 3.72 | Parasympathetic neural control of canine tracheal smooth muscle. ( Hayama, N; Kobayashi, I; Kondo, T; Tazaki, G, 2004) |
| " B6 mice continued to exhibit posthypoxic PB; however, the PB was characterized by longer cycle and apnea length." | 3.72 | 7-nitroindazole and posthypoxic ventilatory behavior in the A/J and C57BL/6J mouse strains. ( Dick, TE; Han, F; Price, ER; Strohl, KP, 2003) |
| " At all ages, hypoxic decline was ascribable mainly to a VT decrease, and posthypoxic decline was ascribable to a T(TOT) increase with apneas, suggesting different underlying neuronal mechanisms." | 3.71 | Maturation of baseline breathing and of hypercapnic and hypoxic ventilatory responses in newborn mice. ( Autret, F; Dauger, S; Gallego, J; Gaultier, C; Renolleau, S; Vardon, G, 2001) |
| " This undershoot may lead to apnea and to a transient destabilization of the control system if the peripheral chemoreflex gain and time delay are twofold greater than basal." | 3.71 | An integrated model of the human ventilatory control system: the response to hypoxia. ( Avanzolini, G; Magosso, E; Ursino, M, 2001) |
| " We performed spectral analysis of RR and MSNA variability during each of the following interventions: 1) controlled breathing, 2) maximal end-expiratory apnea, 3) isocapnic voluntary hyperventilation, and 4) hypercapnia-induced hyperventilation." | 3.71 | Importance of ventilation in modulating interaction between sympathetic drive and cardiovascular variability. ( Degaute, JP; Malliani, A; Montano, N; Narkiewicz, K; Pagani, M; Somers, VK; Van De Borne, P, 2001) |
| " In contrast, phasic (expiratory) thyroarytenoid muscle electromyogram activity, number of short apneas, and incidence of Biot periodic breathing were similarly increased at all three ages." | 3.70 | Developmental changes in respiratory, febrile, and cardiovascular responses to PGE(2) in newborn lambs. ( Adamson, SL; Tai, TC, 2000) |
| "It has previously been reported that active glottic adduction is present during prolonged apneas but absent during periods of breathing movements in fetal lambs in utero." | 3.70 | Coordination between glottic adductor muscle and diaphragm EMG activity in fetal lambs in utero. ( Diaz, V; Dorion, D; Kianicka, I; Praud, JP, 1998) |
| "The effects of hypoxemia and hypercapnia in acute cardiovascular response to periodic non-obstructive apneas were explored in seven preinstrumented, sedated paralyzed and ventilated pigs under three conditions: room air breathing (RA), O2 supplementation (O2), and supplementation with O2 and CO2 (CO2)." | 3.70 | Role of hypoxemia and hypercapnia in acute cardiovascular response to periodic apneas in sedated pigs. ( Chen, L; Greenberg, H; Scharf, SM; Sica, AL, 1998) |
| " Dopamine-induced apneas resulted in tonic activation of the MPC and TA at a level equal to or greater than control activity but no recruitment of IPC activity." | 3.70 | Respiratory-related pharyngeal constrictor muscle activity in awake goats. ( Bisgard, GE; Herman, JK; O'Halloran, KD, 1999) |
| " When blood volume remains approximately constant, as derived from the spectrophotometry data, good correlation is seen between calculated plots made of changes in the transverse relaxation rate, delta R2*, and the oxygen saturation as measured by spectrophotometry for much of the time course of the respiratory challenges of anoxia, apnea and hypercapnia." | 3.69 | Comparison of EPI gradient-echo contrast changes in cat brain caused by respiratory challenges with direct simultaneous evaluation of cerebral oxygenation via a cranial window. ( Balaban, RS; DesPres, D; Heineman, F; Jezzard, P; Taylor, J; Turner, R; Wen, H, 1994) |
| " However, for both animal and human studies, we have demonstrated that if the subjects breathed 100% oxygen in advance of apnea for a short time, T2*-weighted MR brain signal increased when breathing was stopped for a period of 30-60 s." | 3.69 | EPI imaging of global increase of brain MR signal with breath-hold preceded by breathing O2. ( Davis, TL; Donahue, KM; Kwong, KK; Rosen, BR; Wanke, I, 1995) |
| "9 kg) with apnea-induced hypoxic and hypercarbic cardiopulmonary arrest." | 3.69 | Effects of different techniques of endotracheal epinephrine administration in pediatric porcine hypoxic-hypercarbic cardiopulmonary arrest. ( Finkelstein, MS; Jasani, MS; Mandell, GA; Nadkarni, VM; Norman, ME; Salzman, SK, 1994) |
| " Spontaneous rhythmic changes in bronchial diameter and tracheal muscle tension occurred in phase with phrenic burst during mechanical ventilation and during apnea induced by disconnecting the ventilator." | 3.69 | Differences in motor control in the bronchus and extrathoracic trachea. ( Arita, H; Hirokawa, Y; Kobayashi, I; Kondo, T; Ohta, Y; Suda, S, 1995) |
| "This study was carried out on seven chloralose-anesthetized sheep and was designed to investigate the role of muscular afferent fiber stimulation on the duration of reflex apnea triggered by laryngeal stimulation (LS)." | 3.69 | Laryngeal reflex apnea is blunted during and after hindlimb muscle contraction in sheep. ( Beyaert, C; Chalon, B; Gille, JP; Haouzi, P; Marchal, F, 1997) |
| " In all animals, there was a falloff in the intensity of central drive before apnea, with intensity of central drive remaining submaximal throughout loading." | 3.69 | Effects of oxygenation and hypercapnia on diaphragmatic function and central drive during respiratory failure. ( Ferguson, GT, 1995) |
| " Responses to simulated diving were elicited by nasal water flow with concurrent apnea in paralyzed, artificially ventilated Sprague-Dawley rats anesthetized with Innovar." | 3.68 | Cardiovascular responses to nasal water flow in rats are unaffected by chemoreceptor drive. ( McCulloch, PF; West, NH, 1992) |
| " In either case, apnea persisted after coughing subsided." | 3.68 | Influence of central respiratory activity on the cough response in anesthetized dogs. ( Kobayashi, I; Kondo, T; Ohta, Y; Suzuki, H; Yamabayashi, H, 1991) |
| "Arousal is an important protective mechanism that aids in the resolution of obstructive sleep apnea in adults and children, but its role in neonatal apnea has not been investigated." | 3.68 | Behavioral arousal in newborn infants and its association with termination of apnea. ( Belan, MA; Cowen, CP; Mathew, OP; Thoppil, CK, 1991) |
| " The length of time to the onset of apnea became shorter as the O2 concentration became lower." | 3.68 | The interaction between severe hypercapnia and hypoxia. ( Fukui, Y; Watanabe, H; Yamamoto, K; Yamamoto, Y, 1990) |
| "The mechanisms underlying the apnea associated with both hypoxia and high-voltage electrocortical activity (HV ECOG) in the fetal lamb are not clearly understood." | 3.67 | Lateral pontine lesions affect central chemosensitivity in unanesthetized fetal lambs. ( Gluckman, PD; Johnston, BM, 1989) |
| " The PaCO2 rate of rise during apnea in awake subjects was determined to acquire a value that may be more applicable to awake, ventilator-dependent, critically ill patients." | 3.67 | The carbon dioxide rate of rise in awake apneic humans. ( Downs, JB; Fairley, DS; McDonald, JS; McSweeney, TD; Silver, MJ; Stock, MC, 1988) |
| " Under increased gain conditions, five male subjects developed periodic breathing with recurrent cycles of hyperventilation and apnea; the remaining subjects had nonperiodic patterns of hyperventilation." | 3.67 | Possible mechanisms of periodic breathing during sleep. ( Bruce, EN; Chapman, KR; Cherniack, NS; Gothe, B, 1988) |
| " The most striking effect of maturation on apnea was a greater proportion of apnea lasting greater than 1 min, but the total duration of apnea as a percent of a total recording remained unchanged." | 3.67 | Maturation of spontaneous fetal diaphragmatic activity and fetal response to hypercapnia and hypoxemia. ( Chernick, V; Ioffe, S; Jansen, AH, 1987) |
| "We examined the clinical and respiratory physiologic characteristics of 18 patients in whom a diagnosis of central sleep apnea syndrome was established by overnight polysomnographic studies." | 3.67 | Clinical and physiologic heterogeneity of the central sleep apnea syndrome. ( Bradley, TD; McNicholas, WT; Phillipson, EA; Popkin, J; Rutherford, R; Zamel, N, 1986) |
| "The effects of hypoxia and hypercapnea in the production of somatostatin (SRIF)-induced apnea were studied during rebreathing experiments." | 3.67 | Somatostatin-induced apnea: interaction with hypoxia and hypercapnea in the rat. ( Agnati, LF; Fuxe, K; Harfstrand, A; Kaijser, L; Kalia, M, 1984) |
| " Fifty-eight percent of the observations with fetal apnea (FBM 0 to 9% in 2 hours) showed hypoxia (PaO2 less than or equal to 16 torr), whereas only 4% of the observations with FBM greater than 10% were associated with hypoxia." | 3.66 | Effect of oxygen and of carbon dioxide tension on the incidence of apnea in fetal lambs. ( Bissonnette, JM; Cronan, JZ; Hohimer, AR; Paul, MS, 1980) |
| "Five series of breath-hold (BH) experiments were conducted on eight male subjects with the purpose of partitioning the effects of apnea per se, hypercapnia, and hypoxia on the development and maintenance of BH bradycardia." | 3.66 | Effects of hypercapnia, hypoxia, and rebreathing on heart rate response during apnea. ( Hong, SK; Lin, YC; Shida, KK, 1983) |
| " A spectrum of breathing abnormalities was found ranging from no abnormalities to severe episodes of prolonged central apnea." | 3.66 | Sleep breathing abnormalities in kyphoscoliosis. ( Israels, J; Kryger, M; Mezon, BL; West, P, 1980) |
| " The results show that occlusions at the end of inspiration or inflations provoked an apnea in both cats and humans." | 3.66 | Breuer-Hering inflation reflex and breathing pattern in anesthetized humans and cats. ( Bonora, M; Gaudy, JH; Gautier, H, 1981) |
| "The present study was designed to investigate the effect of stimulus duration and chemosensory input on the recovery of central respiratory activity from apnea induced by superior laryngeal nerve (SLN) electrical stimulation." | 3.66 | Recovery from central apnea: effect of stimulus duration and end-tidal CO2 partial pressure. ( Lawson, EE, 1982) |
| " Average respiratory rate increased (90%) and fetal apnea decreased (60%) during hypercapnia." | 3.66 | Hypercapnic stimulation of respiratory activity in unanesthetized fetal sheep in utero. ( Bowes, G; Brodecky, V; Dowling, M; Maloney, JE; Ritchie, BC; Wilkinson, MH, 1981) |
| "The study of electrocardiogram and opercular movement records, from eels exposed for prolonged periods to hypercarbic water (saturation by the gaseous mixture 2% CO2, 98% air) shows that 1) heart rate is not significantly changed; 2) the duration of spontaneous apnea phases and the magnitude of opercular movements during ventilatory phases are increased under hypercapnic conditions." | 3.65 | [Cardiorespiratory effects of exogenous hypercapnia in eels]. ( Barthelemy, L; Belaud, A; Peyraud, C; Sebert, P; Soulier, P, 1976) |
| " torr increased RA from apnea to 76% of the animals' maximal hypercapnic response and decreased f: further increases in PIco2 to VIL had only minimal effects on RA and f." | 3.65 | Ventilatory responses to CO2 in the chicken: intrapulmonary and systemic chemoreceptors. ( Mitchell, GS; Osborne, JL; Powell, F, 1977) |
| "Twelve patients with predominantly obstructive type sleep apnea underwent cardiac catheterization, hemodynamic monitoring, and arterial blood gas analysis during wakefulness and sleep." | 3.65 | Hemodynamics in sleep-induced apnea. Studies during wakefulness and sleep. ( Dement, WC; Guilleminault, C; Lehrman, KL; Schroeder, JS; Simmons, FB; Tilkian, AG, 1976) |
| " In contrast to the sustained stimulation of ventilation produced by hypoxia in normal subjects, hypoxia either did not change, or decreased, the [unk]V(E)-P(ACo2) slope of dysautonomic patients and phenoxybenzamine-treated goats; CO(2)-free hypoxia produced a fleeting hyperventilation, which was followed by apnea when hypoxia was abruptly relieved." | 3.65 | The effects of abnormal sympathetic nervous function upon the ventilatory response to hypoxia. ( Cherniack, NS; Edelman, NH; Fishman, AP; Lahiri, S; Richards, E, 1970) |
| "To investigate whether breathlessness induced in normal volunteers by different stimuli represents one or more than one sensation, we studied 30 subjects in whom breathlessness was induced by each of 8 different stimuli: breath-holding, CO2 inhalation, inhalation of CO2, with ventilation voluntarily targeted below the level dictated by chemical drive, breathing with a resistive load, breathing with an elastic load, voluntary elevation of functional residual capacity, voluntary limitation of tidal volume, and exercise." | 1.28 | Distinguishable sensations of breathlessness induced in normal volunteers. ( Fencl, V; Lahive, K; Schwartzstein, RM; Simon, PM; Teghtsoonian, M; Weinberger, SE; Weiss, JW, 1989) |
| "Alveolar hypercapnia was terminated during an experimental period by changing the gas mixture back to room air once the animal aroused from sleep." | 1.28 | Influence of carotid-denervation on the arousal and cardiopulmonary responses to alveolar hypercapnia in lambs. ( Dascalu, V; Fewell, JE; Filyk, SC; Kondo, CS, 1989) |
Research
Studies (153)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 51 (33.33) | 18.7374 |
| 1990's | 27 (17.65) | 18.2507 |
| 2000's | 32 (20.92) | 29.6817 |
| 2010's | 35 (22.88) | 24.3611 |
| 2020's | 8 (5.23) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Sugiyama, A | 1 |
| Terada, J | 1 |
| Shionoya, Y | 1 |
| Hirano, S | 1 |
| Yamamoto, T | 1 |
| Yamanaka, Y | 1 |
| Araki, N | 1 |
| Koshikawa, K | 1 |
| Kasai, H | 1 |
| Ikeda, S | 1 |
| Wang, J | 1 |
| Koide, K | 1 |
| Ito, S | 1 |
| Kuwabara, S | 1 |
| Dolscheid-Pommerich, RC | 1 |
| Stoffel-Wagner, B | 1 |
| Fimmers, R | 1 |
| Eichhorn, L | 2 |
| Bailey, DM | 2 |
| Bain, AR | 3 |
| Hoiland, RL | 2 |
| Barak, OF | 3 |
| Drvis, I | 3 |
| Hirtz, C | 1 |
| Lehmann, S | 1 |
| Marchi, N | 1 |
| Janigro, D | 1 |
| MacLeod, DB | 3 |
| Ainslie, PN | 4 |
| Dujic, Z | 7 |
| MacMillan, S | 1 |
| Holmes, AP | 1 |
| Dallas, ML | 1 |
| Mahmoud, AD | 1 |
| Shipston, MJ | 1 |
| Peers, C | 1 |
| Hardie, DG | 1 |
| Kumar, P | 1 |
| Evans, AM | 1 |
| Pape, P | 1 |
| Piosik, ZM | 1 |
| Kristensen, CM | 1 |
| Dirks, J | 1 |
| Rasmussen, LS | 1 |
| Kristensen, MS | 1 |
| Crescimanno, G | 1 |
| Greco, F | 1 |
| Canino, M | 1 |
| Bertini, M | 1 |
| Marrone, O | 1 |
| Toor, RUAS | 1 |
| Sun, QJ | 1 |
| Kumar, NN | 1 |
| Le, S | 1 |
| Hildreth, CM | 1 |
| Phillips, JK | 1 |
| McMullan, S | 1 |
| Barrett, KT | 1 |
| Hasan, SU | 2 |
| Scantlebury, MH | 1 |
| Wilson, RJA | 1 |
| Bruce, CD | 1 |
| Vanden Berg, ER | 1 |
| Pfoh, JR | 1 |
| Steinback, CD | 2 |
| Day, TA | 1 |
| Bourdas, DI | 2 |
| Geladas, ND | 2 |
| Gustafsson, IM | 1 |
| Lodenius, Å | 1 |
| Tunelli, J | 1 |
| Ullman, J | 1 |
| Jonsson Fagerlund, M | 1 |
| Young, JO | 1 |
| Geurts, A | 1 |
| Hodges, MR | 1 |
| Cummings, KJ | 3 |
| Laviola, M | 1 |
| Das, A | 1 |
| Chikhani, M | 1 |
| Bates, DG | 1 |
| Hardman, JG | 1 |
| Tenorio-Lopes, L | 1 |
| Henry, MS | 1 |
| Marques, D | 1 |
| Tremblay, MÈ | 1 |
| Drolet, G | 1 |
| Bretzner, F | 1 |
| Kinkead, R | 3 |
| Amorim, MR | 1 |
| de Deus, JL | 1 |
| Lumb, KJ | 1 |
| Schneider, JM | 1 |
| Ibrahim, T | 1 |
| Rigaux, A | 1 |
| Elliot-Portal, E | 1 |
| Laouafa, S | 2 |
| Arias-Reyes, C | 1 |
| Janes, TA | 1 |
| Joseph, V | 3 |
| Soliz, J | 2 |
| Harrar, DB | 1 |
| Kukreti, V | 1 |
| Dean, NP | 1 |
| Berger, JT | 1 |
| Carpenter, JL | 1 |
| Moir, ME | 1 |
| Klassen, SA | 1 |
| Al-Khazraji, BK | 1 |
| Woehrle, E | 1 |
| Smith, SO | 1 |
| Matushewski, BJ | 1 |
| Kozić, D | 1 |
| Shoemaker, JK | 3 |
| Usselman, CW | 1 |
| Luchyshyn, TA | 1 |
| Gimon, TI | 1 |
| Nielson, CA | 1 |
| Van Uum, SH | 1 |
| Aruj, PK | 1 |
| Monteiro, SG | 1 |
| De Vito, EL | 1 |
| Levin, D | 1 |
| Burckett-St Laurent, D | 1 |
| Wong, DT | 1 |
| Marcouiller, F | 1 |
| Boukari, R | 1 |
| Lavoie, R | 1 |
| Tsakiris, TS | 1 |
| Pavlakis, KI | 1 |
| Triantafillou, DV | 1 |
| Shah, V | 1 |
| Lazaridis, C | 1 |
| Jouett, NP | 1 |
| Watenpaugh, DE | 1 |
| Dunlap, ME | 1 |
| Smith, ML | 3 |
| Heitzmann, D | 1 |
| Buehler, P | 1 |
| Schweda, F | 1 |
| Georgieff, M | 1 |
| Warth, R | 1 |
| Thomas, J | 1 |
| Cavar, M | 1 |
| Stembridge, M | 1 |
| MacLeod, DM | 1 |
| Kessler, F | 1 |
| Böhnert, V | 1 |
| Erdfelder, F | 1 |
| Reckendorf, A | 1 |
| Meyer, R | 1 |
| Ellerkmann, RK | 1 |
| Andersson, JP | 1 |
| Schagatay, E | 2 |
| Commons, KG | 1 |
| Fan, KC | 1 |
| Li, A | 1 |
| Nattie, EE | 1 |
| Seyal, M | 1 |
| Bateman, LM | 1 |
| Steggerda, JA | 1 |
| Mayer, CA | 2 |
| Martin, RJ | 3 |
| Wilson, CG | 1 |
| Uglesic, L | 1 |
| Breskovic, T | 2 |
| Valic, Z | 2 |
| Heusser, K | 2 |
| Marinovic, J | 1 |
| Ljubkovic, M | 1 |
| Palada, I | 2 |
| Sharma, VK | 1 |
| Teoh, HL | 1 |
| Chan, BP | 1 |
| Hårdemark Cedborg, AI | 1 |
| Bodén, K | 1 |
| Witt Hedström, H | 1 |
| Kuylenstierna, R | 1 |
| Ekberg, O | 1 |
| Eriksson, LI | 1 |
| Sundman, E | 1 |
| Banic, I | 1 |
| Mathew, OP | 2 |
| Nemati, S | 1 |
| Edwards, BA | 1 |
| Sands, SA | 1 |
| Berger, PJ | 1 |
| Wellman, A | 1 |
| Verghese, GC | 1 |
| Malhotra, A | 1 |
| Butler, JP | 1 |
| Richardson, MX | 1 |
| Engan, HK | 1 |
| Lodin-Sundström, A | 1 |
| Niane, LM | 1 |
| Bairam, A | 3 |
| Ren, J | 1 |
| Ding, X | 1 |
| Greer, JJ | 1 |
| Seitz, MJ | 1 |
| Brown, R | 1 |
| Macefield, VG | 1 |
| Guensch, DP | 1 |
| Fischer, K | 1 |
| Flewitt, JA | 1 |
| Friedrich, MG | 1 |
| Fournier, S | 2 |
| Steele, S | 1 |
| Julien, C | 1 |
| Gulemetova, R | 1 |
| Caravagna, C | 1 |
| Xia, L | 1 |
| Leiter, JC | 1 |
| Bartlett, D | 1 |
| Aizenfisz, S | 1 |
| Dauger, S | 2 |
| Durand, E | 1 |
| Vardon, G | 2 |
| Levacher, B | 1 |
| Simonneau, M | 1 |
| Pachnis, V | 1 |
| Gaultier, C | 2 |
| Gallego, J | 2 |
| Przybyłowski, T | 1 |
| Bangash, MF | 1 |
| Reichmuth, K | 1 |
| Morgan, BJ | 1 |
| Skatrud, JB | 1 |
| Dempsey, JA | 2 |
| Harris, MB | 1 |
| Milsom, WK | 1 |
| Velez-Roa, S | 1 |
| Kojonazarov, B | 1 |
| Ciarka, A | 1 |
| Godart, P | 1 |
| Naeije, R | 1 |
| Somers, VK | 3 |
| van de Borne, P | 3 |
| Price, ER | 1 |
| Han, F | 1 |
| Dick, TE | 2 |
| Strohl, KP | 1 |
| DAY, SB | 1 |
| GRIFFEN, WO | 1 |
| CASTANEDA, A | 1 |
| NICOLOFF, DM | 1 |
| DOBERNECK, C | 1 |
| STONE, NH | 1 |
| NAHAS, GG | 1 |
| JORDAN, EC | 1 |
| LIGOU, JC | 1 |
| Cutler, MJ | 2 |
| Swift, NM | 2 |
| Keller, DM | 2 |
| Wasmund, WL | 2 |
| Abu-Shaweesh, JM | 2 |
| Baird, TM | 1 |
| Burk, JR | 1 |
| Kobayashi, I | 3 |
| Kondo, T | 3 |
| Hayama, N | 1 |
| Tazaki, G | 1 |
| Norman, RG | 1 |
| Goldring, RM | 1 |
| Clain, JM | 1 |
| Oppenheimer, BW | 1 |
| Charney, AN | 1 |
| Rapoport, DM | 1 |
| Berger, KI | 1 |
| Montandon, G | 1 |
| Adachi, T | 1 |
| Ogawa, H | 1 |
| Okabe, S | 1 |
| Kitamuro, T | 1 |
| Kikuchi, Y | 1 |
| Shibahara, S | 1 |
| Shirato, K | 1 |
| Hida, W | 1 |
| Itoh, M | 1 |
| Ueoka, H | 1 |
| Aoki, T | 1 |
| Hotta, N | 1 |
| Kaneko, Y | 1 |
| Takita, C | 1 |
| Fukuoka, Y | 1 |
| Swart, M | 1 |
| Yang, SJ | 1 |
| Lee, KZ | 1 |
| Wu, CH | 1 |
| Lu, KT | 1 |
| Hwang, JC | 1 |
| Duvareille, C | 1 |
| Lafrance, M | 1 |
| Samson, N | 1 |
| St-Hilaire, M | 1 |
| Pladys, P | 1 |
| Micheau, P | 1 |
| Bournival, V | 1 |
| Langlois, C | 1 |
| Praud, JP | 2 |
| Huang, ZG | 1 |
| Griffioen, KJ | 1 |
| Wang, X | 1 |
| Dergacheva, O | 1 |
| Kamendi, H | 1 |
| Gorini, C | 1 |
| Mendelowitz, D | 1 |
| Gujic, M | 1 |
| Dreyfuss, C | 1 |
| Argacha, JF | 1 |
| Beloka, S | 1 |
| Adamopoulos, D | 1 |
| Xhaët, O | 1 |
| Pathak, A | 1 |
| Ivancev, V | 1 |
| Dzamonja, G | 1 |
| Tank, J | 1 |
| Obad, A | 1 |
| Bakovic, D | 1 |
| Diedrich, A | 1 |
| Joyner, MJ | 1 |
| Jordan, J | 1 |
| Mesner, O | 1 |
| Miller, MJ | 1 |
| Iben, SC | 1 |
| Prabha, KC | 1 |
| Haxhiu, MA | 1 |
| Calladine, M | 1 |
| Gairdner, D | 1 |
| Hall, LW | 1 |
| Monahan, CM | 1 |
| Purchase, IF | 1 |
| Harfstrand, A | 1 |
| Kalia, M | 1 |
| Fuxe, K | 1 |
| Kaijser, L | 1 |
| Agnati, LF | 1 |
| Read, DJ | 1 |
| Henderson-Smart, DJ | 1 |
| Lin, YC | 2 |
| Shida, KK | 2 |
| Hong, SK | 2 |
| Bissonnette, JM | 1 |
| Hohimer, AR | 1 |
| Cronan, JZ | 1 |
| Paul, MS | 1 |
| Bowes, G | 1 |
| Wilkinson, MH | 1 |
| Dowling, M | 1 |
| Ritchie, BC | 1 |
| Brodecky, V | 1 |
| Maloney, JE | 1 |
| Lawson, EE | 1 |
| Bruce, EN | 2 |
| Gautier, H | 1 |
| Bonora, M | 1 |
| Gaudy, JH | 1 |
| Mezon, BL | 1 |
| West, P | 1 |
| Israels, J | 1 |
| Kryger, M | 1 |
| Jounieaux, V | 1 |
| Aubert, G | 1 |
| Dury, M | 1 |
| Delguste, P | 1 |
| Rodenstein, DO | 1 |
| Ferguson, GT | 1 |
| Kwong, KK | 1 |
| Wanke, I | 1 |
| Donahue, KM | 1 |
| Davis, TL | 1 |
| Rosen, BR | 1 |
| Jasani, MS | 1 |
| Nadkarni, VM | 1 |
| Finkelstein, MS | 1 |
| Mandell, GA | 1 |
| Salzman, SK | 1 |
| Norman, ME | 1 |
| Héritier, F | 1 |
| Feihl, F | 1 |
| Jezzard, P | 1 |
| Heineman, F | 1 |
| Taylor, J | 1 |
| DesPres, D | 1 |
| Wen, H | 1 |
| Balaban, RS | 1 |
| Turner, R | 1 |
| Schobel, HP | 1 |
| Ferguson, DW | 1 |
| Clary, MP | 1 |
| Leevers, AM | 1 |
| Simon, PM | 2 |
| Xi, L | 1 |
| Hirokawa, Y | 1 |
| Suda, S | 1 |
| Ohta, Y | 2 |
| Arita, H | 1 |
| Haouzi, P | 1 |
| Beyaert, C | 1 |
| Gille, JP | 1 |
| Chalon, B | 1 |
| Marchal, F | 1 |
| Schäfer, T | 1 |
| Schläfke, ME | 1 |
| Kianicka, I | 1 |
| Diaz, V | 1 |
| Dorion, D | 1 |
| Chen, L | 1 |
| Sica, AL | 1 |
| Greenberg, H | 1 |
| Scharf, SM | 1 |
| Combes, JC | 1 |
| Nicolas, F | 1 |
| Lenfant, F | 1 |
| Cros, N | 1 |
| D'Athis, P | 1 |
| Freysz, M | 1 |
| Hudgel, DW | 1 |
| Thanakitcharu, S | 1 |
| Carl, ML | 1 |
| Schelegle, ES | 1 |
| Hollstien, SB | 1 |
| Green, JF | 1 |
| Chin, K | 1 |
| Oku, Y | 1 |
| Nishimura, K | 1 |
| Ohi, M | 1 |
| Katz-Salamon, M | 1 |
| Milerad, J | 1 |
| Legrand, A | 1 |
| De Troyer, A | 1 |
| O'Halloran, KD | 1 |
| Herman, JK | 1 |
| Bisgard, GE | 1 |
| Sleigh, JW | 1 |
| Tai, TC | 1 |
| Adamson, SL | 1 |
| Montano, N | 1 |
| Narkiewicz, K | 1 |
| Degaute, JP | 1 |
| Malliani, A | 1 |
| Pagani, M | 1 |
| Ursino, M | 1 |
| Magosso, E | 1 |
| Avanzolini, G | 1 |
| Delapille, P | 2 |
| Verin, E | 2 |
| Tourny-Chollet, C | 2 |
| Pasquis, P | 2 |
| Renolleau, S | 1 |
| Autret, F | 1 |
| Waters, KA | 1 |
| McBrien, F | 1 |
| Stewart, P | 1 |
| Hinder, M | 1 |
| Wharton, S | 1 |
| Sebert, P | 1 |
| Soulier, P | 1 |
| Barthelemy, L | 1 |
| Belaud, A | 1 |
| Peyraud, C | 1 |
| Guilleminault, C | 3 |
| Farmer, WC | 1 |
| Glenn, WW | 1 |
| Gee, JB | 1 |
| St John, WM | 1 |
| Wang, SC | 1 |
| Osborne, JL | 1 |
| Mitchell, GS | 1 |
| Powell, F | 1 |
| Stromme, SB | 1 |
| Blix, AS | 1 |
| Tilkian, AG | 1 |
| Schroeder, JS | 1 |
| Lehrman, KL | 1 |
| Simmons, FB | 1 |
| Dement, WC | 1 |
| Immonen, I | 1 |
| McCulloch, PF | 1 |
| West, NH | 1 |
| Suzuki, H | 1 |
| Yamabayashi, H | 1 |
| Thoppil, CK | 1 |
| Belan, MA | 1 |
| Cowen, CP | 1 |
| Ebata, T | 1 |
| Watanabe, Y | 1 |
| Amaha, K | 1 |
| Hosaka, Y | 1 |
| Takagi, S | 1 |
| Watanabe, H | 1 |
| Yamamoto, K | 1 |
| Yamamoto, Y | 1 |
| Fukui, Y | 1 |
| Kelsen, SG | 1 |
| Schwartzstein, RM | 1 |
| Weiss, JW | 1 |
| Lahive, K | 1 |
| Fencl, V | 1 |
| Teghtsoonian, M | 1 |
| Weinberger, SE | 1 |
| Fewell, JE | 1 |
| Kondo, CS | 1 |
| Dascalu, V | 1 |
| Filyk, SC | 1 |
| Johnston, BM | 1 |
| Gluckman, PD | 1 |
| Stock, MC | 1 |
| Downs, JB | 2 |
| McDonald, JS | 1 |
| Silver, MJ | 1 |
| McSweeney, TD | 1 |
| Fairley, DS | 1 |
| Chapman, KR | 1 |
| Gothe, B | 1 |
| Cherniack, NS | 2 |
| Ioffe, S | 1 |
| Jansen, AH | 1 |
| Chernick, V | 1 |
| Bradley, TD | 1 |
| McNicholas, WT | 1 |
| Rutherford, R | 1 |
| Popkin, J | 1 |
| Zamel, N | 1 |
| Phillipson, EA | 2 |
| James, HE | 1 |
| Vanuxem, P | 1 |
| Lavaivre, M | 1 |
| Delpierre, S | 1 |
| Jammes, Y | 1 |
| Grimaud, C | 1 |
| Buckfield, PM | 1 |
| Malcolm, DS | 1 |
| Modell, JH | 1 |
| Calderwood, HW | 1 |
| Ruiz, BC | 1 |
| Chapman, R | 1 |
| Counts, HK | 1 |
| Carden, WD | 1 |
| Petty, WC | 1 |
| Nevsímal, O | 1 |
| Nevsímalová, S | 1 |
| Oouredník, A | 1 |
| Butler, PJ | 1 |
| Taylor, EW | 1 |
| Jenkins, AV | 1 |
| Sammons, HG | 1 |
| Maxwell, GM | 1 |
| Daily, WJ | 1 |
| Meyer, HB | 1 |
| Sunshine, P | 1 |
| Smith, PC | 1 |
| Farber, JP | 1 |
| Hanquet, M | 1 |
| Bellucci, G | 1 |
| Auchincloss, JH | 1 |
| Gilbert, R | 1 |
| Edelman, NH | 1 |
| Lahiri, S | 1 |
| Richards, E | 1 |
| Fishman, AP | 1 |
| Bouverot, P | 1 |
| Crance, JP | 1 |
| Dejours, P | 1 |
| Hickey, RF | 1 |
| Bainton, CR | 1 |
| Nadel, JA | 1 |
| Ferrante, FL | 1 |
| Miller, BD | 1 |
| Stein, JF | 1 |
| Widdicombe, JG | 1 |
| Benzer, H | 1 |
| Kunz, H | 1 |
| Lempert, J | 1 |
| Mayrhofer, O | 1 |
| Muhar, F | 1 |
| Campbell, EJ | 1 |
| Godfrey, S | 1 |
| Clark, TJ | 1 |
| Freedman, S | 1 |
| Norman, J | 1 |
| James, JE | 1 |
| Daly, Mde B | 1 |
Clinical Trials (9)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Oxygenation by 100% Oxygen Via High Flow Nasal Cannula During Apnea in Adult Elective Surgical ENT Patients[NCT02706431] | 31 participants (Actual) | Interventional | 2015-12-01 | Completed | |||
| Physiology Regarding Apnoeic Oxygenation During Nasal Cannula Therapy at Different Flow Rates[NCT03478774] | 125 participants (Actual) | Interventional | 2018-03-25 | Completed | |||
| Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Apnoeic Ventilation During Operative Hysteroscopic Procedures Under General Anesthesia: an Observational Study.[NCT05291117] | 30 participants (Actual) | Observational | 2022-02-01 | Completed | |||
| Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures[NCT03430206] | 78 participants (Actual) | Interventional | 2018-02-21 | Completed | |||
| Evaluation the Efficiency of Intravenous Dexmedetomidine Under Nasal Humidification Rapid Ventilation Device Without Intubation in Laryngoscope Microsurgery[NCT05581485] | 90 participants (Anticipated) | Interventional | 2022-11-29 | Recruiting | |||
| High Flow Oxygen During ProcEdural Sedation for Operative Hysteroscopy: a Randomized Controlled Trial - HOPE Study.[NCT05550584] | 180 participants (Actual) | Interventional | 2022-06-17 | Completed | |||
| Breathing-Induced Myocardial Oxygenation Reserve - Pilot Study (B-MORE-Pilot)[NCT03050346] | 113 participants (Actual) | Observational | 2016-01-31 | Completed | |||
| Impact of Breathing Maneuvers and Oxygen Administration on Myocardial Oxygenation in Patients With Coronary Artery Disease Compared With Healthy Controls - Non-invasive Assessment With Oxygenation-sensitive Cardiovascular Magnetic Resonance Imaging (OS-CM[NCT02233634] | 36 participants (Actual) | Interventional | 2014-10-01 | Completed | |||
| Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery in Persons With Chronic SCI: The BO2ST Trial[NCT05563103] | 60 participants (Anticipated) | Interventional | 2023-01-17 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
End-Tidal Carbon Dioxide (ETCO2)
Ventilation was measured with transcutaneous carbon dioxide sensor (NCT03430206)
Timeframe: Duration of surgery (generally less than 2 hours)
| Intervention | mmHg (Mean) |
|---|---|
| Standard of Care | 51.6 |
| THRIVE | 52.8 |
Incidence of Adverse Events
(NCT03430206)
Timeframe: Up to 12 hours
| Intervention | Events (Mean) |
|---|---|
| Standard of Care | 0.183 |
| THRIVE | 0.268 |
Number of Oxygen Desaturation Events <90% or Defined by a 5% Fall From Baseline if Baseline Saturation < 94%.
Relative incidence of oxygen desaturation as measured by pulse oximetry by second adjusted for post surgical diagnosis (NCT03430206)
Timeframe: Duration of surgery (generally less than 2 hours)
| Intervention | Events (Mean) |
|---|---|
| Standard of Care | 0.536 |
| THRIVE | 0.268 |
Number of Surgical Interruptions
Number of surgical interruptions defined by a pause in surgical procedures due to need to intervene, normalized to case length. (NCT03430206)
Timeframe: Duration of surgery (generally less than 2 hours)
| Intervention | Interruptions (Mean) |
|---|---|
| Standard of Care | 0.645 |
| THRIVE | 0.302 |
Oxygen Desaturation Index
Oxygen desaturation index is defined as the number of times a patient has a 4% decrease in saturation from a 120 second rolling mean for greater than 10 seconds (NCT03430206)
Timeframe: Duration of surgery (generally less than 2 hours)
| Intervention | Events (Mean) |
|---|---|
| Standard of Care | 1.09 |
| THRIVE | 0.312 |
Post-surgical Diagnosis
Location of lesion(s) according to post-surgical diagnosis (NCT03430206)
Timeframe: Duration of surgery (generally less than 2 hours)
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Supraglottic | Infraglottic | Both Supraglottic and Infraglottic | |
| Standard of Care | 2 | 13 | 3 |
| THRIVE | 10 | 10 | 1 |
Reviews
10 reviews available for apnea and Hypercapnia
| Article | Year |
|---|---|
Physiology of static breath holding in elite apneists.
Topics: Adaptation, Physiological; Animals; Apnea; Breath Holding; Cerebrovascular Circulation; Humans; Hype | 2018 |
Apnea testing on extracorporeal membrane oxygenation: Case report and literature review.
Topics: Adult; Apnea; Brain Death; Continuous Positive Airway Pressure; Extracorporeal Membrane Oxygenation; | 2015 |
Apnea of prematurity: pathogenesis and management strategies.
Topics: Apnea; Arrhythmias, Cardiac; Brain Stem; Caffeine; Central Nervous System Stimulants; Continuous Pos | 2011 |
Apnoea of prematurity.
Topics: Apnea; Continuous Positive Airway Pressure; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, P | 2004 |
Maturation of respiratory reflex responses in the fetus and neonate.
Topics: Acidosis; Afferent Pathways; Age Factors; Animals; Apnea; Fetus; Humans; Hypercapnia; Hypoxia; Infan | 2004 |
Regulation of breathing in the newborn during different behavioral states.
Topics: Airway Obstruction; Animals; Animals, Newborn; Apnea; Arousal; Behavior; Behavior, Animal; Cough; Di | 1984 |
Control of breathing in the newborn.
Topics: Animals; Animals, Newborn; Apnea; Biomedical Engineering; Carbon Dioxide; Cats; Chemoreceptor Cells; | 1981 |
[Diving: physical and physiological bases].
Topics: Apnea; Atmospheric Pressure; Barotrauma; Decompression Sickness; Digestive System; Diving; Dyspnea; | 1994 |
Pharmacologic treatment of sleep-disordered breathing.
Topics: Acetazolamide; Antihypertensive Agents; Apnea; Bronchodilator Agents; Diuretics; Dyspnea; Evidence-B | 1998 |
[Retinopathy of prematurity].
Topics: Apnea; Humans; Hypercapnia; Hypocapnia; Infant, Newborn; Oxygen; Retinopathy of Prematurity | 1991 |
Trials
9 trials available for apnea and Hypercapnia
| Article | Year |
|---|---|
Repeated apneas and hypercapnic ventilatory response before and after apnea training.
Topics: Adaptation, Physiological; Apnea; Breath Holding; Carbon Dioxide; Double-Blind Method; Humans; Hyper | 2015 |
Inhibition of augmented muscle vasoconstrictor drive following asphyxic apnoea in awake human subjects is not affected by relief of chemical drive.
Topics: Adolescent; Adult; Analysis of Variance; Apnea; Asphyxia; Blood Pressure; Breath Holding; Carbon Dio | 2013 |
Mechanisms of the cerebrovascular response to apnoea in humans.
Topics: Adrenergic alpha-Agonists; Adult; Apnea; Cerebrovascular Circulation; Female; Ganglionic Blockers; H | 2003 |
Dobutamine potentiates arterial chemoreflex sensitivity in healthy normal humans.
Topics: Adrenergic beta-Agonists; Adult; Apnea; Arteries; Blood Pressure; Chemoreceptor Cells; Dobutamine; E | 2003 |
Periods of intermittent hypoxic apnea can alter chemoreflex control of sympathetic nerve activity in humans.
Topics: Adult; Apnea; Blood Pressure; Chemoreceptor Cells; Female; Humans; Hypercapnia; Hypoxia; Male; Refle | 2004 |
Effects of enoximone on peripheral and central chemoreflex responses in humans.
Topics: Adult; Apnea; Cardiac Output; Central Nervous System; Chemoreceptor Cells; Cross-Over Studies; Enoxi | 2008 |
Differential effects of digitalis on chemoreflex responses in humans.
Topics: Adult; Apnea; Carbon Dioxide; Chemoreceptor Cells; Digitalis Glycosides; Double-Blind Method; Female | 1994 |
Effects of OSA, inhalational anesthesia, and fentanyl on the airway and ventilation of children.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Apnea; Carbon Dioxide; Child; Child, Preschool; Drug Sy | 2002 |
State of the art. Sleep and control of breathing.
Topics: Adolescent; Adult; Airway Obstruction; Animals; Apnea; Carbon Dioxide; Cats; Child; Clinical Trials | 1978 |
Other Studies
134 other studies available for apnea and Hypercapnia
| Article | Year |
|---|---|
Sleep-related hypoventilation and hypercapnia in multiple system atrophy detected by polysomnography with transcutaneous carbon dioxide monitoring.
Topics: Apnea; Carbon Dioxide; Humans; Hypercapnia; Hypoventilation; Multiple System Atrophy; Polysomnograph | 2022 |
Changes in hormones after apneic hypoxia/hypercapnia - An investigation in voluntary apnea divers.
Topics: Adrenal Cortex Hormones; Adult; Apnea; Diving; Female; Gonadal Steroid Hormones; Gonadotropins, Pitu | 2022 |
Hypoxemia increases blood-brain barrier permeability during extreme apnea in humans.
Topics: Apnea; Blood-Brain Barrier; Humans; Hypercapnia; Hypoxia; Permeability | 2022 |
LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Apnea; Carotid Body; Humans; Hy | 2022 |
Transcutaneous carbon dioxide monitoring during prolonged apnoea with high-flow nasal oxygen.
Topics: Apnea; Carbon Dioxide; Humans; Hypercapnia; Oxygen; Respiration, Artificial | 2023 |
Contribution of transcutaneous capnography to the interpretation of abnormal respiratory events during noninvasive ventilation.
Topics: Amyotrophic Lateral Sclerosis; Apnea; Blood Gas Monitoring, Transcutaneous; Capnography; Chronic Dis | 2019 |
Neurons in the Intermediate Reticular Nucleus Coordinate Postinspiratory Activity, Swallowing, and Respiratory-Sympathetic Coupling in the Rat.
Topics: Animals; Apnea; Central Pattern Generators; Choline O-Acetyltransferase; Deglutition; Female; Hyperc | 2019 |
Impaired cardiorespiratory responses to hypercapnia in neonatal mice lacking PAC1 but not VPAC2 receptors.
Topics: Animals; Animals, Newborn; Apnea; Body Weight; Carbon Dioxide; Female; Gene Expression Regulation; G | 2021 |
Prior oxygenation, but not chemoreflex responsiveness, determines breath-hold duration during voluntary apnea.
Topics: Adult; Apnea; Breath Holding; Chemoreceptor Cells; Female; Humans; Hypercapnia; Hypoxia; Lung; Male; | 2021 |
Five repeated maximal efforts of apneas increase the time to exhaustion in subsequent high-intensity exercise.
Topics: Acidosis; Adult; Apnea; Athletic Performance; Bicycling; Exercise; Humans; Hypercapnia; Male; Physic | 2021 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Apnea; Carbon Dioxide; Female; Hemodynamics; Hu | 2017 |
Active sleep unmasks apnea and delayed arousal in infant rat pups lacking central serotonin.
Topics: Animals; Animals, Newborn; Apnea; Arousal; Gene Knockout Techniques; Humans; Hypercapnia; Hypoxia; I | 2017 |
Investigating the effect of cardiac oscillations and deadspace gas mixing during apnea using computer simulation.
Topics: Animals; Apnea; Carbon Dioxide; Computer Simulation; Dogs; Hypercapnia; Partial Pressure; Pulmonary | 2017 |
Neonatal maternal separation opposes the facilitatory effect of castration on the respiratory response to hypercapnia of the adult male rat: Evidence for the involvement of the medial amygdala.
Topics: Animals; Animals, Newborn; Apnea; Corticomedial Nuclear Complex; Hypercapnia; Male; Maternal Depriva | 2017 |
Purinergic signalling and TRPV1 receptors are associated with the carotid body plasticity induced by an apnoea-like stimulus.
Topics: Apnea; Carotid Body; Humans; Hypercapnia; Hypoxia; TRPV Cation Channels | 2018 |
Afferent neural feedback overrides the modulating effects of arousal, hypercapnia and hypoxaemia on neonatal cardiorespiratory control.
Topics: Afferent Pathways; Animals; Animals, Newborn; Apnea; Arousal; Feedback, Physiological; Hypercapnia; | 2018 |
Brain-derived erythropoietin protects from intermittent hypoxia-induced cardiorespiratory dysfunction and oxidative stress in mice.
Topics: Animals; Apnea; Arterial Pressure; Brain; Brain Stem; Cerebral Cortex; Erythropoietin; Heart Rate; H | 2018 |
Clinical Determination of Brain Death in Children Supported by Extracorporeal Membrane Oxygenation.
Topics: Adolescent; Aortic Valve Stenosis; Apnea; Brain Death; Brain Edema; Burns; Cerebral Infarction; Chil | 2019 |
Impaired dynamic cerebral autoregulation in trained breath-hold divers.
Topics: Adult; Apnea; Blood Flow Velocity; Blood Pressure; Brain; Breath Holding; Carbon Dioxide; Cerebrovas | 2019 |
Hormone phase dependency of neural responses to chemoreflex-driven sympathoexcitation in young women using hormonal contraceptives.
Topics: Action Potentials; Adult; Age Factors; Apnea; Chemoreceptor Cells; Contraceptives, Oral, Hormonal; D | 2013 |
[Analysis of factors associated with chronic hypercapnia in patients with myotonic dystrophy].
Topics: Adult; Apnea; Carbon Dioxide; Chronic Disease; Disorders of Excessive Somnolence; Female; Forced Exp | 2013 |
Postoperative apnea and hypercapnia due to intentional breath holding in a freediver.
Topics: Adult; Apnea; Athletes; Breath Holding; Diving; Humans; Hypercapnia; Male; Postoperative Period | 2014 |
The nuclear progesterone receptor reduces post-sigh apneas during sleep and increases the ventilatory response to hypercapnia in adult female mice.
Topics: Aging; Animals; Apnea; Cell Nucleus; Electroencephalography; Electromyography; Female; Hypercapnia; | 2014 |
Interactive effects of hypoxia, hypercapnia and lung volume on sympathetic nerve activity in humans.
Topics: Adult; Apnea; Blood Pressure; Carbon Dioxide; Chemoreceptor Cells; Female; Heart Rate; Humans; Hyper | 2015 |
The in vivo respiratory phenotype of the adenosine A1 receptor knockout mouse.
Topics: Aging; Animals; Animals, Newborn; Apnea; Blood Gas Analysis; Disease Models, Animal; Female; Hyperca | 2016 |
Cerebral oxidative metabolism is decreased with extreme apnoea in humans; impact of hypercapnia.
Topics: Adult; Apnea; Arterial Pressure; Blood Flow Velocity; Blood Gas Analysis; Brain; Cerebrovascular Cir | 2016 |
A Model to Simulate Clinically Relevant Hypoxia in Humans.
Topics: Apnea; Carbon Dioxide; Diving; Humans; Hypercapnia; Hypoxia; Oximetry; Oxygen; Partial Pressure; Spe | 2016 |
Repeated apneas do not affect the hypercapnic ventilatory response in the short term.
Topics: Adult; Apnea; Carbon Dioxide; Female; Humans; Hypercapnia; Male; Oxygen Consumption; Pulmonary Venti | 2009 |
Severe spontaneous bradycardia associated with respiratory disruptions in rat pups with fewer brain stem 5-HT neurons.
Topics: 5,7-Dihydroxytryptamine; Adaptation, Physiological; Age Factors; Animals; Animals, Newborn; Apnea; A | 2009 |
Ictal apnea linked to contralateral spread of temporal lobe seizures: Intracranial EEG recordings in refractory temporal lobe epilepsy.
Topics: Apnea; Brain Mapping; Death, Sudden; Electrocardiography; Electrodes, Implanted; Electroencephalogra | 2009 |
Effect of intermittent hypercapnia on respiratory control in rat pups.
Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Chemoreceptor Cells; Diaphragm; Disease Models, An | 2010 |
Involuntary breathing movements improve cerebral oxygenation during apnea struggle phase in elite divers.
Topics: Adult; Apnea; Blood Pressure; Cerebrovascular Circulation; Diving; Female; Heart Rate; Hemoglobins; | 2009 |
Cerebral vasomotor reactivity in epilepsy patients.
Topics: Apnea; Cerebral Arteries; Cerebrovascular Circulation; Epilepsy; Humans; Hypercapnia; Inhalation; Va | 2010 |
Breathing and swallowing in normal man--effects of changes in body position, bolus types, and respiratory drive.
Topics: Adult; Apnea; Deglutition; Drive; Female; Humans; Hypercapnia; Male; Manometry; Posture; Pressure; R | 2010 |
Autonomic and cardiovascular responses to chemoreflex stress in apnoea divers.
Topics: Adaptation, Physiological; Adult; Apnea; Autonomic Nervous System; Baroreflex; Blood Pressure; Cardi | 2010 |
Model-based characterization of ventilatory stability using spontaneous breathing.
Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Carotid Body; Domperidone; Dopamine Antagonists; D | 2011 |
Effect of hypercapnia on spleen-related haemoglobin increase during apnea.
Topics: Adult; Apnea; Blood Pressure; Carbon Dioxide; Diving; Female; Heart Rate; Hematocrit; Hemoglobin A; | 2012 |
Systemic blockade of nicotinic and purinergic receptors inhibits ventilation and increases apnoea frequency in newborn rats.
Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Drug Therapy, Combination; Female; Hexamethonium; | 2012 |
Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717.
Topics: Animals; Apnea; Barbiturates; Brain Stem; Ethanol; Hypercapnia; Hypoxia; Isoxazoles; Male; Oxygen; P | 2012 |
Impact of intermittent apnea on myocardial tissue oxygenation--a study using oxygenation-sensitive cardiovascular magnetic resonance.
Topics: Animals; Apnea; Blood Gas Analysis; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Hypercap | 2013 |
Impact of intermittent apnea on myocardial tissue oxygenation--a study using oxygenation-sensitive cardiovascular magnetic resonance.
Topics: Animals; Apnea; Blood Gas Analysis; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Hypercap | 2013 |
Impact of intermittent apnea on myocardial tissue oxygenation--a study using oxygenation-sensitive cardiovascular magnetic resonance.
Topics: Animals; Apnea; Blood Gas Analysis; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Hypercap | 2013 |
Impact of intermittent apnea on myocardial tissue oxygenation--a study using oxygenation-sensitive cardiovascular magnetic resonance.
Topics: Animals; Apnea; Blood Gas Analysis; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Hypercap | 2013 |
Gestational stress promotes pathological apneas and sex-specific disruption of respiratory control development in newborn rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Apnea; Corticosterone; Female; Hy | 2013 |
Laryngeal reflex apnea in neonates: effects of CO2 and the complex influence of hypoxia.
Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Chemoreceptor Cells; Female; Hypercapnia; Hypocapn | 2013 |
Ventilatory responses to hypercapnia and hypoxia in heterozygous c-ret newborn mice.
Topics: Animals; Animals, Newborn; Apnea; Drosophila Proteins; Female; Genotype; Heterozygote; Homozygote; H | 2002 |
Apneusis follows disruption of NMDA-type glutamate receptors in vagotomized ground squirrels.
Topics: Animals; Apnea; Dizocilpine Maleate; Drug Administration Routes; Excitatory Amino Acid Antagonists; | 2003 |
7-nitroindazole and posthypoxic ventilatory behavior in the A/J and C57BL/6J mouse strains.
Topics: Animals; Apnea; Carbon Dioxide; Enzyme Inhibitors; Hypercapnia; Hypoxia; Indazoles; Mice; Mice, Inbr | 2003 |
Potentiating influence of apnea, hypoxia, and hypercapnia on bile-induced hemorrhagic pancreatic necrosis.
Topics: Apnea; Bile; Carbon Dioxide; Disease; Hypercapnia; Hypoxia; Necrosis; Pancreas; Pancreatic Diseases | 1960 |
Effects of a 'carbon dioxide buffer' on hypercapnia of apneic oxygenation.
Topics: Amino Alcohols; Apnea; Buffers; Carbon Dioxide; Glycols; Humans; Hypercapnia; Oxygen Inhalation Ther | 1959 |
Hypoxia-mediated prolonged elevation of sympathetic nerve activity after periods of intermittent hypoxic apnea.
Topics: Adult; Apnea; Blood Pressure; Female; Heart Rate; Humans; Hypercapnia; Hypoxia; Male; Peroneal Nerve | 2004 |
Parasympathetic neural control of canine tracheal smooth muscle.
Topics: Animals; Apnea; Dogs; Efferent Pathways; Hypercapnia; Muscle Contraction; Muscle, Smooth; Parasympat | 2004 |
Transition from acute to chronic hypercapnia in patients with periodic breathing: predictions from a computer model.
Topics: Acute Disease; Apnea; Bicarbonates; Carbon Dioxide; Chronic Disease; Computer Simulation; Humans; Hy | 2006 |
Long-term consequences of neonatal caffeine on ventilation, occurrence of apneas, and hypercapnic chemoreflex in male and female rats.
Topics: Animals; Animals, Newborn; Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Hyper | 2006 |
Mice with blunted hypoxic ventilatory response are susceptible to respiratory disturbance during hypoxia.
Topics: Adaptation, Physiological; Animals; Apnea; Disease Models, Animal; Hypercapnia; Hypoxia; Male; Mice; | 2006 |
Exercise hyperpnea and hypercapnic ventilatory responses in women.
Topics: Adult; Apnea; Carbon Dioxide; Exercise; Exercise Test; Female; Follicular Phase; Humans; Hypercapnia | 2007 |
Morning attenuation in cerebrovascular CO2 reactivity in healthy humans is associated with a lowered cerebral oxygenation and an augmented ventilatory response to CO2.
Topics: Adult; Apnea; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulation; Chemoreceptor Cells; | 2007 |
Vasopressin produces inhibition on phrenic nerve activity and apnea through V(1A) receptors in the area postrema in rats.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Apnea; Area Postrema; Arginine Vasopressin; Bloo | 2006 |
Effects of hypoxia and hypercapnia on nonnutritive swallowing in newborn lambs.
Topics: Animals; Animals, Newborn; Apnea; Deglutition; Diaphragm; Electrocardiography; Electroencephalograph | 2007 |
Nicotinic receptor activation occludes purinergic control of central cardiorespiratory network responses to hypoxia/hypercapnia.
Topics: Animals; Apnea; Brain Stem; Cardiovascular System; Data Interpretation, Statistical; Excitatory Post | 2007 |
Central chemoreflex sensitivity and sympathetic neural outflow in elite breath-hold divers.
Topics: Adult; Apnea; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Chemoreceptor Cells; Diving; Femo | 2008 |
Hyperbilirubinemia diminishes respiratory drive in a rat pup model.
Topics: Animals; Animals, Newborn; Apnea; Bilirubin; Brain Stem; Disease Models, Animal; Dose-Response Relat | 2008 |
Bronchial insufflation in hypoventilation.
Topics: Anesthesia, General; Animals; Apnea; Bronchi; Carbon Dioxide; Dogs; Hypercapnia; Hypoventilation; Ox | 1967 |
Somatostatin-induced apnea: interaction with hypoxia and hypercapnea in the rat.
Topics: Animals; Apnea; Brain Mapping; Chemoreceptor Cells; Hypercapnia; Hypoxia; Male; Medulla Oblongata; R | 1984 |
Effects of hypercapnia, hypoxia, and rebreathing on heart rate response during apnea.
Topics: Adult; Apnea; Carbon Dioxide; Heart Rate; Humans; Hypercapnia; Hypoxia; Male; Oxygen; Pulmonary Alve | 1983 |
Effect of oxygen and of carbon dioxide tension on the incidence of apnea in fetal lambs.
Topics: Animals; Apnea; Carbon Dioxide; Female; Fetus; Gestational Age; Hypercapnia; Movement; Oxygen; Respi | 1980 |
Hypercapnic stimulation of respiratory activity in unanesthetized fetal sheep in utero.
Topics: Animals; Apnea; Carbon Dioxide; Cerebral Cortex; Diaphragm; Electromyography; Female; Fetus; Gestati | 1981 |
Recovery from central apnea: effect of stimulus duration and end-tidal CO2 partial pressure.
Topics: Animals; Animals, Newborn; Apnea; Blood Pressure; Carbon Dioxide; Electric Stimulation; Hypercapnia; | 1982 |
Effects of hypercapnia, hypoxia, and rebreathing on circulatory response to apnea.
Topics: Adult; Apnea; Blood Circulation; Cardiac Output; Humans; Hypercapnia; Hypoxia; Male; Stroke Volume; | 1983 |
Breuer-Hering inflation reflex and breathing pattern in anesthetized humans and cats.
Topics: Adult; Airway Obstruction; Anesthesia; Animals; Apnea; Cats; Female; Humans; Hypercapnia; Pressure; | 1981 |
Sleep breathing abnormalities in kyphoscoliosis.
Topics: Adult; Aged; Apnea; Female; Humans; Hypercapnia; Hypoxia; Kyphosis; Male; Middle Aged; Oxygen; Respi | 1980 |
Effects of nasal positive-pressure hyperventilation on the glottis in normal sleeping subjects.
Topics: Adult; Apnea; Carbon Dioxide; Female; Glottis; Humans; Hypercapnia; Hyperventilation; Male; Nose; Po | 1995 |
Effects of oxygenation and hypercapnia on diaphragmatic function and central drive during respiratory failure.
Topics: Animals; Apnea; Blood Gas Analysis; Diaphragm; Electric Stimulation; Hypercapnia; Male; Muscle Contr | 1995 |
EPI imaging of global increase of brain MR signal with breath-hold preceded by breathing O2.
Topics: Animals; Apnea; Brain; Carbon Dioxide; Echo-Planar Imaging; Hemoglobins; Humans; Hypercapnia; Image | 1995 |
Effects of different techniques of endotracheal epinephrine administration in pediatric porcine hypoxic-hypercarbic cardiopulmonary arrest.
Topics: Animals; Apnea; Drug Evaluation, Preclinical; Epinephrine; Heart Arrest; Hypercapnia; Hypoxia; Insti | 1994 |
Comparison of EPI gradient-echo contrast changes in cat brain caused by respiratory challenges with direct simultaneous evaluation of cerebral oxygenation via a cranial window.
Topics: Animals; Apnea; Arteries; Brain; Cats; Hypercapnia; Hypoxia; Magnetic Resonance Spectroscopy; Oxygen | 1994 |
Apnoea following normocapnic mechanical ventilation in awake mammals: a demonstration of control system inertia.
Topics: Adult; Animals; Apnea; Carbon Dioxide; Dogs; Feedback; Female; Humans; Hypercapnia; Lung Transplanta | 1993 |
Differences in motor control in the bronchus and extrathoracic trachea.
Topics: Animals; Apnea; Blood Gas Analysis; Bronchi; Dogs; Electric Stimulation; Hypercapnia; Muscle Contrac | 1995 |
Laryngeal reflex apnea is blunted during and after hindlimb muscle contraction in sheep.
Topics: Animals; Apnea; Electric Stimulation; Female; Hindlimb; Hypercapnia; Hypoxia; Injections; Larynx; Mu | 1997 |
[Postnatal development of breathing control].
Topics: Apnea; Carbon Dioxide; Chemoreceptor Cells; Embryonic and Fetal Development; Humans; Hypercapnia; In | 1997 |
Coordination between glottic adductor muscle and diaphragm EMG activity in fetal lambs in utero.
Topics: Animals; Apnea; Deglutition; Diaphragm; Electroencephalography; Electromyography; Eye Movements; Fet | 1998 |
Role of hypoxemia and hypercapnia in acute cardiovascular response to periodic apneas in sedated pigs.
Topics: Acute Disease; Animals; Apnea; Cardiovascular System; Electroencephalography; Female; Gases; Hemodyn | 1998 |
[Hemodynamic changes induced by apnea test in patients with brain death].
Topics: Acidosis, Respiratory; Adult; Apnea; Brain Death; Female; Hemodynamics; Humans; Hypercapnia; Hyperte | 1996 |
Control of ventilation during lung volume changes and permissive hypercapnia in dogs.
Topics: Adaptation, Physiological; Animals; Apnea; Carbon Dioxide; Dogs; Expiratory Reserve Volume; Function | 1998 |
Deep breathing and awake apnoea in a patient who had recurrent hypoxaemia and hypercapnia without sleep apnoea.
Topics: Acetazolamide; Adult; Apnea; Humans; Hypercapnia; Hypoxia; Magnetic Resonance Imaging; Male; Respira | 1998 |
The divergent ventilatory and heart rate response to moderate hypercapnia in infants with apnoea of infancy.
Topics: Apnea; Carbon Dioxide; Female; Heart Rate; Humans; Hypercapnia; Infant; Male; Partial Pressure; Recu | 1998 |
Spatial distribution of external and internal intercostal activity in dogs.
Topics: Animals; Apnea; Dogs; Electric Stimulation; Electromyography; Electrophysiology; Hypercapnia; Interc | 1999 |
Respiratory-related pharyngeal constrictor muscle activity in awake goats.
Topics: Animals; Apnea; Chemoreceptor Cells; Dopamine; Electromyography; Goats; Hypercapnia; Hypoxia; Muscle | 1999 |
Postoperative respiratory arrhythmias: incidence and measurement.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Analysis of Variance; Apnea; Female; Fo | 1999 |
Developmental changes in respiratory, febrile, and cardiovascular responses to PGE(2) in newborn lambs.
Topics: Age Factors; Animals; Animals, Newborn; Apnea; Blood Pressure; Body Temperature Regulation; Carbon D | 2000 |
Importance of ventilation in modulating interaction between sympathetic drive and cardiovascular variability.
Topics: Adult; Apnea; Carbon Dioxide; Chemoreceptor Cells; Electrocardiography; Female; Heart Rate; Humans; | 2001 |
An integrated model of the human ventilatory control system: the response to hypoxia.
Topics: Apnea; Carbon Dioxide; Chemoreceptor Cells; Humans; Hypercapnia; Hypoxia; Models, Theoretical; Respi | 2001 |
Breath-holding time: effects of non-chemical factors in divers and non-divers.
Topics: Adaptation, Physiological; Adult; Apnea; Carbon Dioxide; Diving; Humans; Hypercapnia; Linear Models; | 2001 |
Maturation of baseline breathing and of hypercapnic and hypoxic ventilatory responses in newborn mice.
Topics: Animals; Animals, Newborn; Apnea; Body Weight; Female; Hypercapnia; Hypoxia; Male; Mice; Plethysmogr | 2001 |
Ventilatory responses to hypercapnia in divers and non-divers: effects of posture and immersion.
Topics: Adaptation, Physiological; Air; Apnea; Carbon Dioxide; Diving; Functional Residual Capacity; Helium; | 2001 |
[Cardiorespiratory effects of exogenous hypercapnia in eels].
Topics: Animals; Apnea; Eels; Heart Rate; Hypercapnia; Respiration | 1976 |
Advances in the pathology of sleep.
Topics: Adult; Apnea; Blood Pressure; Disorders of Excessive Somnolence; Heart Arrest; Humans; Hypercapnia; | 1978 |
Alveolar hypoventilation syndrome. Studies of ventilatory control in patients selected for diaphragm pacing.
Topics: Adolescent; Adult; Aged; Apnea; Carbon Dioxide; Diaphragm; Electric Stimulation; Female; Humans; Hyp | 1978 |
Integration of chemoreceptor stimuli by caudal pontile and rostral medullary sites.
Topics: Animals; Apnea; Carbon Dioxide; Cats; Chemoreceptor Cells; Female; Hypercapnia; Hypoxia; Male; Medul | 1976 |
Ventilatory responses to CO2 in the chicken: intrapulmonary and systemic chemoreceptors.
Topics: Animals; Apnea; Carbon Dioxide; Chemoreceptor Cells; Hypercapnia; Lung; Male; Respiration; Respirato | 1977 |
Indirect evidence for arterial chemoreceptor reflex facilitation by face immersion in man.
Topics: Adult; Apnea; Chemoreceptor Cells; Face; Heart Rate; Humans; Hypercapnia; Immersion; Male; Physical | 1976 |
Hemodynamics in sleep-induced apnea. Studies during wakefulness and sleep.
Topics: Adult; Airway Obstruction; Apnea; Blood Gas Analysis; Cardiac Catheterization; Hemodynamics; Humans; | 1976 |
Cardiovascular responses to nasal water flow in rats are unaffected by chemoreceptor drive.
Topics: Animals; Apnea; Cardiovascular Physiological Phenomena; Cardiovascular System; Chemoreceptor Cells; | 1992 |
Influence of central respiratory activity on the cough response in anesthetized dogs.
Topics: Afferent Pathways; Anesthesia; Animals; Apnea; Cough; Dogs; Electromyography; Hypercapnia; Physical | 1991 |
Behavioral arousal in newborn infants and its association with termination of apnea.
Topics: Airway Obstruction; Apnea; Arousal; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, Premature | 1991 |
Haemodynamic changes during the apnoea test for diagnosis of brain death.
Topics: Adult; Aged; Apnea; Blood Pressure; Brain Death; Carbon Dioxide; Cardiac Output; Dobutamine; Dopamin | 1991 |
The interaction between severe hypercapnia and hypoxia.
Topics: Animals; Apnea; Carbon Dioxide; Hypercapnia; Hypoxia; Male; Oxygen; Rabbits; Respiration | 1990 |
Relationship between diaphragmatic activation and twitch tension to superimposed electrical stimulation in the cat.
Topics: Animals; Apnea; Carbon Dioxide; Cats; Diaphragm; Electric Stimulation; Hypercapnia; Isometric Contra | 1989 |
Distinguishable sensations of breathlessness induced in normal volunteers.
Topics: Adult; Apnea; Carbon Dioxide; Cluster Analysis; Dyspnea; Exercise; Female; Humans; Hypercapnia; Male | 1989 |
Influence of carotid-denervation on the arousal and cardiopulmonary responses to alveolar hypercapnia in lambs.
Topics: Animals; Apnea; Arousal; Carotid Body; Carotid Sinus; Chemoreceptor Cells; Denervation; Disease Mode | 1989 |
Lateral pontine lesions affect central chemosensitivity in unanesthetized fetal lambs.
Topics: Acidosis, Lactic; Animals; Apnea; Chemoreceptor Cells; Electroencephalography; Female; Fetus; Hyperc | 1989 |
The carbon dioxide rate of rise in awake apneic humans.
Topics: Adult; Apnea; Carbon Dioxide; Consciousness; Functional Residual Capacity; Humans; Hypercapnia; Lung | 1988 |
Possible mechanisms of periodic breathing during sleep.
Topics: Adult; Apnea; Blood Gas Analysis; Cheyne-Stokes Respiration; Electroencephalography; Female; Humans; | 1988 |
Maturation of spontaneous fetal diaphragmatic activity and fetal response to hypercapnia and hypoxemia.
Topics: Animals; Apnea; Diaphragm; Electromyography; Female; Fetus; Gestational Age; Hypercapnia; Hypoxia; P | 1987 |
Clinical and physiologic heterogeneity of the central sleep apnea syndrome.
Topics: Adult; Airway Resistance; Apnea; Blood Gas Analysis; Electrocardiography; Humans; Hypercapnia; Male; | 1986 |
Absent hypoxic and hypercapnic arousal responses in children with myelomeningocele and apnea.
Topics: Apnea; Arousal; Child; Humans; Hypercapnia; Hypoxia; Meningomyelocele | 1987 |
[Influence of blood gasometry modifications on the Hering Breuer reflex in rabbits].
Topics: Animals; Apnea; Blood Gas Analysis; Carbon Dioxide; Hypercapnia; Hyperventilation; Hypoxia; Oxygen; | 1971 |
Mechanical positive pressure ventilation of the newborn.
Topics: Apnea; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, Premature, Diseases; Positive-Pressure | 1972 |
Effects of ventilatory patterns on arterial oxygenation after near-drowning in sea water.
Topics: Acidosis, Respiratory; Adult; Animals; Apnea; Blood; Carbon Dioxide; Dogs; Drowning; Humans; Hydroge | 1974 |
Use of the Fluotec Mark II for halothane-air anesthesia.
Topics: Adolescent; Adult; Anesthesia, Inhalation; Apnea; Blood Gas Analysis; Chromatography, Gas; Evaluatio | 1973 |
[Sleep disorders and periodic respiration in obese subjects].
Topics: Adult; Apnea; Electromyography; Humans; Hypercapnia; Male; Middle Aged; Obesity; Periodicity; Respir | 1973 |
The effect of hypercapnic hypoxia, accompanied by different levels of lung ventilation, on heart rate in the duck.
Topics: Animals; Apnea; Blood Pressure; Carbon Dioxide; Diving; Ducks; Heart Rate; Hypercapnia; Hypoxia; Oxy | 1973 |
Carbon dioxide elimination during bronchoscopy. A comparison of two alternative general anaesthetic techniques.
Topics: Analysis of Variance; Anesthesia, General; Apnea; Arrhythmias, Cardiac; Blood Specimen Collection; B | 1968 |
Experimental drowning: coronary haemodynamics and myocardial metabolism in the dog.
Topics: Animals; Apnea; Blood Flow Velocity; Blood Glucose; Blood Pressure; Cardiac Output; Coronary Vessels | 1970 |
Mechanical ventilation of newborn infants. 3. Historical comments and development of a scoring system for selection of infants.
Topics: Acidosis; Apnea; Bicarbonates; Bradycardia; Carbon Dioxide; Heart Arrest; Humans; Hydrogen-Ion Conce | 1971 |
Development of pulmonary reflexes and pattern of breathing in Virginia opossum.
Topics: Aging; Animals; Apnea; Asphyxia; Diaphragm; Electromyography; Humans; Hypercapnia; Hypoxia; Intercos | 1972 |
[Physiopathology of drowning].
Topics: Apnea; Blood Pressure; Drowning; Fresh Water; Heart; Humans; Hypercapnia; Hypoxia; Immersion; Lung; | 1972 |
[Cholinesterase and prolonged apnea due to succinylcholine].
Topics: Adult; Anesthesia; Apnea; Cholinesterases; Female; Humans; Hydrolysis; Hypercapnia; Male; Middle Age | 1971 |
An evaluation of the negative phase of a volume-limited ventilator.
Topics: Adult; Aged; Apnea; Cardiac Output; Female; Humans; Hypercapnia; Hypotension; Infant, Newborn; Male; | 1967 |
The effects of abnormal sympathetic nervous function upon the ventilatory response to hypoxia.
Topics: Animals; Apnea; Blood Pressure; Central Nervous System; Chemoreceptor Cells; Dysautonomia, Familial; | 1970 |
Factors influencing the intensity of the Breuer-Hering inspiration-inhibiting reflex.
Topics: Anesthesia; Animals; Apnea; Dogs; Hypercapnia; Lung; Lung Compliance; Neurons, Afferent; Partial Pre | 1970 |
Effect of vagal blockade on regulation of breathing in conscious dogs.
Topics: Animals; Apnea; Arteries; Carbon Dioxide; Consciousness; Dogs; Female; Fever; Hypercapnia; Hypoxia; | 1970 |
Respiratory insensitivity to blood gases in nutrias (Myocastor coypus).
Topics: Acidosis, Respiratory; Adaptation, Physiological; Animals; Apnea; Carbon Dioxide; Carnivora; Diving; | 1971 |
Interaction of reflexes from chemo- and pulmonary stretch receptors in control of airway calibre.
Topics: Airway Resistance; Animals; Apnea; Carbon Dioxide; Chemoreceptor Cells; Dilatation; Dogs; Hypercapni | 1971 |
[On the significance of oxygen supply in drug induced central respiratory depression].
Topics: Animals; Apnea; Carbon Dioxide; Fentanyl; Hypercapnia; Hypoxia; Neuroleptanalgesia; Oxygen Consumpti | 1967 |
The effect of muscular paralysis induced by tubocurarine on the duration and sensation of breath-holding during hypercapnia.
Topics: Apnea; Atropine; Carbon Dioxide; Humans; Hypercapnia; Male; Paralysis; Respiration; Sensation; Spiro | 1969 |
Cardiovascular responses in apnoeic asphyxia: role of arterial chemoreceptors and the modification of their effects by a pulmonary vagal inflation reflex.
Topics: Animals; Apnea; Asphyxia; Carbon Dioxide; Chemoreceptor Cells; Dogs; Hypercapnia; Hypoxia; Lung; Oxy | 1969 |