apnea and Birth Weight studies

Birth Weight: The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.

Research Excerpts

Excerpt	Relevance	Reference
"Methylxanthines, including caffeine, theophylline, and aminophylline, work as stimulants of the respiratory drive, and decrease apnea of prematurity, a developmental disorder common in preterm infants."	9.41	Caffeine versus other methylxanthines for the prevention and treatment of apnea in preterm infants. ( Bruschettini, M; Marques, KA; Moresco, L; Sjögren, A; Soll, R, 2023)
"Preterm infants with apnea who were born at less than 32 weeks of gestational age and birth weight ≤1500 g were randomly divided into caffeine citrate prevention group and caffeine citrate treatment group."	9.34	Influence of prevention of caffeine citrate on cytokine profile and bronchopulmonary dysplasia in preterm infants with apnea. ( Gao, Z; Han, D; Kou, C; Li, Z; Liu, Z; Wu, W; Zhang, Y, 2020)
"Caffeine therapy for apnea of prematurity did not significantly reduce the combined rate of academic, motor, and behavioral impairments but was associated with a reduced risk of motor impairment in 11-year-old children with very low birth weight."	9.24	Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity: An 11-Year Follow-up of the CAP Randomized Clinical Trial. ( Anderson, PJ; Asztalos, EV; Costantini, L; D'Ilario, J; Davis, PG; Dewey, D; Doyle, LW; Grunau, RE; Moddemann, D; Nelson, H; Ohlsson, A; Roberts, RS; Schmidt, B; Solimano, A; Tin, W, 2017)
" This low-cost neuromodulatory procedure has the potential to provide a non-invasive intervention to reduce apnea, bradycardia and intermittent hypoxia in premature neonates."	9.22	Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia. ( Benharash, P; Cordero, DM; Frank, P; Harper, RM; Kesavan, K, 2016)
"To evaluate the effectiveness and safety of different doses of caffeine in treatment of primary apnea in preterm infants."	9.22	[Clinical effectiveness of different doses of caffeine for primary apnea in preterm infants]. ( Liu, G; Tian, X; Zhao, Y, 2016)
" Apneic events and bradycardia did not occur in the low-dose group; however, there were three episodes of apnea (42."	9.19	A comparative study of two remifentanil doses for procedural pain in ventilated preterm infants: a randomized, controlled study*. ( Choi, JH; Choi, KY; Kim, EK; Kim, HS; Lee, J; Lee, JH; Park, MS; Shin, SH, 2014)
"Fifteen infants, median gestational age at birth 27 weeks (range 24-30), age at study 27 days (12-60), with >/=6 episodes of bradycardia or hypoxaemia/6 h despite serum caffeine levels in the therapeutic range, received doxapram either intravenously (0."	9.09	Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants. ( Bohnhorst, B; Darraj, S; Poets, CF, 1999)
"Controversy exists as to the risk for postoperative apnea in former preterm infants."	9.08	Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. ( Coté, CJ; Downes, JJ; Kurth, CD; Malviya, SV; Warner, LO; Welborn, LG; Zaslavsky, A, 1995)
"To assess if there was any advantage in the prophylactic use of theophylline to prevent apnea in preterms, we treated 56 preterms (Group A) < 34 weeks gestation with theophylline infusion and compared these with 25 age and weight matched preterms (Group B) who received no therapy."	9.07	Prophylactic theophylline infusion for prevention of apnea of prematurity. ( Ashavaid, TF; Merchant, RH; Sakhalkar, VS, 1992)
"To investigate claims that oscillating mattresses reduce apnea of prematurity and improve growth and neurobehavioural development, we performed a randomized clinical trial using a predetermined sample size."	9.06	Randomized clinical trial of an oscillating air mattress in preterm infants: effect on apnea, growth, and development. ( Campbell, D; Saigal, S; Watts, J, 1986)
"19 infants admitted with a diagnosis of infantile apnea who were found to have periodic breathing were given oral theophylline to determine its effect."	9.05	An evaluation of theophylline for idiopathic apnea of infancy. ( Coward, JH; Duffley, LM; Finer, NN; Peters, KL, 1984)
"It has been suggested that idiopathic apnea of prematurity is related to hypoxia from pulmonary instability or an immaturity of central respiratory control mechanisms."	9.04	Apnea of prematurity. Comparative therapeutic effects of cutaneous stimulation and nasal continuous positive airway pressure. ( Fanaroff, AA; Katona, PG; Kattwinkel, J; Klaus, MH; Nearman, HS, 1975)
" It is thanks to the efforts of Barbara Schmidt and the Caffeine for Apnea of Prematurity (CAP) Trial Group that we now have high-quality and reliable data not only on short-term but also long-term outcomes of caffeine use for apnea of prematurity."	8.90	Caffeine for apnea of prematurity: a neonatal success story. ( Bassler, D; Kreutzer, K, 2014)
" Percentage total sleep time (%TST) with respiratory events (isolated apneas, sequential apneas and periodic breathing (PB)) at each study was calculated."	8.31	Developmental consequences of short apneas and periodic breathing in preterm infants. ( Horne, RSC; Nixson, GM; Siriwardhana, LS; Walter, LM; Wong, FY; Yee, AK, 2023)
"5 million babies born prematurely, and up to 40% of them are babies with low birth weights, highly prone to a multitude of diseases such as Jaundice, Sepsis, Apnea, and other Metabolic disorders."	7.91	Optimizing neural networks for medical data sets: A case study on neonatal apnea prediction. ( Acharya U, D; Lewis U, LES; M, S; Makkithaya, K; Shirwaikar, RD; Srivastava, S, 2019)
"The factors affecting the safety and efficacy of aminophylline use in the treatment of apnea of prematurity (AOP) in the neonatal intensive care unit (NICU) are not clear."	7.91	Factors affecting the efficacy and safety of aminophylline in treatment of apnea of prematurity in neonatal intensive care unit. ( Dong, Z; Lu, X; Lyu, Q; Mao, Y; Miao, C; Ye, C; Yu, L; Zhang, J, 2019)
"Incidence fell from 74% diagnosed with apnea of prematurity at baseline to 49% diagnosed with CSCPE postimplementation (P<0."	7.85	Clinically significant cardiopulmonary events and the effect of definition standardization on apnea of prematurity management. ( Ahlers-Schmidt, CR; Bloom, BT; Engel, M; Powell, MB, 2017)
"This study evaluated the optimal timing for repair, incarceration risk, and postoperative apnea rate in premature infants with inguinal hernias."	7.77	A critical review of premature infants with inguinal hernias: optimal timing of repair, incarceration risk, and postoperative apnea. ( Gleason, JM; Lee, SL; Sydorak, RM, 2011)
"Clinically relevant apneas, which are common in preterm infants, may adversely affect later neuropsychological condition in this group of patients."	7.75	Differential diagnosis of apneas in preterm infants. ( Dittrichová, J; Melichar, J; Miletín, J; Paul, K, 2009)
"Adverse cardiorespiratory events including apnea, bradycardia, and desaturations have been described following administration of the first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B (DTP-IPV-Hib) immunization to preterm infants."	7.73	Frequency of apnea, bradycardia, and desaturations following first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B immunization in hospitalized preterm infants. ( Lee, J; Robinson, JL; Spady, DW, 2006)
"Apnea of prematurity develop during the first days of life and usually resolve by the time the infant reaches 36-37 weeks postmenstrual age."	7.73	[Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate]. ( Baudon, JJ; Biran-Mucignat, V; Boelle, PY; Ducrocq, S; Gold, F; Lebas, F, 2006)
"To identify current factors associated with home apnea monitor use in preterm infants and to determine whether home monitor use was associated with a shorter length of hospital stay."	7.71	Home apnea monitor use in preterm infants discharged from newborn intensive care units. ( Clark, R; Dodd, E; Peabody, J; Perfect Sychowski, S; Thomas, P, 2001)
"Apnea of prematurity is common and none of the treatments being used are fully effective and free of significant adverse side effects."	7.71	Inhalation of low (0.5%-1.5%) CO2 as a potential treatment for apnea of prematurity. ( Al-Aif, S; Alvaro, R; Cates, D; Kwiatkowski, K; Manfreda, J; Rigatto, H, 2001)
"Premature infants need to attain both medical stability and maturational milestones (specifically, independent thermoregulation, resolution of apnea of prematurity, and the ability to feed by mouth) before safe discharge to home."	7.71	Inter-neonatal intensive care unit variation in discharge timing: influence of apnea and feeding management. ( Blackwell, M; Eichenwald, EC; Lloyd, JS; Richardson, DK; Tran, T; Wilker, RE, 2001)
" This study was designed to test the hypothesis that recurrent central apneas in preterm infants are correlated with a reduced prostacyclin to thromboxane A2 ratio."	7.70	Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. ( Bernhard, M; Hoch, B, 1999)
"Recordings of breathing movements and heart rate (pneumograms) were obtained prospectively in 89 preterm infants at 0-28 days of age to determine if those who develop apnea and/or bradycardia with cyanosis (Group 1) differ from those who do not (Group 2)."	7.68	Prospective pneumogram recordings in preterm infants with and without clinical apnea and bradycardia. ( Kelly, DH; McCulloch, KM, 1990)
"The occurrence of central apnea of 15 seconds or longer, transient episodes of bradycardia (TEB), and periodic breathing were studied in 66 healthy premature infants when at least 1 week old and between 32 and 36 weeks postconceptual age."	7.68	Apnea, transient episodes of bradycardia, and periodic breathing in preterm infants. ( Cabal, LA; Gonzalez, F; Hodgman, JE; Hoppenbrouwers, T, 1990)
"Apnea, bradycardia, and neuromuscular hyperirritability have been associated with magnesium (Mg) deficiency in young human infants and weanling animals."	7.67	Magnesium therapy in premature neonates with apnea neonatorum. ( Caddell, JL, 1988)
"To determine the relationship of electrocardiographic changes to both intraventricular hemorrhage (IVH) and neonatal apnea, continuous electrocardiographic monitoring, serial electrocardiograms, and cranial echoencephalograms were obtained on 41 consecutive preterm neonates with birth weight below 1,250 g."	7.67	The electrocardiogram in preterm infants with intraventricular hemorrhage and apnea. ( Colavita, RD; Ment, LR, 1986)
"To evaluate the relationship of antecedent maternal smoking and caffeine consumption habits on the occurrence of apnea in their offspring, rates for central and obstructive apnea were analyzed in a cohort of mother-infant pairs."	7.67	Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study. ( Bendell, D; Duke, JC; Mattice, CD; McCaffree, MA; Orr, WC; Toubas, PL, 1986)
"Twelve premature infants with significant apnea of prematurity while receiving therapeutic doses of aminophylline were given an intravenous infusion of doxapram, 2 or 2."	7.67	Physiologic effects of doxapram in idiopathic apnea of prematurity. ( Barrington, KJ; Barton, J; Finer, NN; Peters, KL, 1986)
"The efficacy of theophylline in preventing severe apnea was evaluated in 17 low-birthweight infants (mean weight, 1,400 gm)."	7.65	Prevention of apnea and bradycardia in low-birthweight infants. ( Gotay, F; Moylan, FM; Rogers, MC; Shannon, DC; Stein, IM; Todres, ID, 1975)
" No over-all pattern relating sleep state to frequency of apnea could be detected for individual infants."	7.65	Sleep state, apnea and bradycardia in pre-term infants. ( Auld, PA; Krauss, AN; Solomon, GE, 1977)
"Methylxanthines, including caffeine, theophylline, and aminophylline, work as stimulants of the respiratory drive, and decrease apnea of prematurity, a developmental disorder common in preterm infants."	5.41	Caffeine versus other methylxanthines for the prevention and treatment of apnea in preterm infants. ( Bruschettini, M; Marques, KA; Moresco, L; Sjögren, A; Soll, R, 2023)
"Preterm infants with apnea who were born at less than 32 weeks of gestational age and birth weight ≤1500 g were randomly divided into caffeine citrate prevention group and caffeine citrate treatment group."	5.34	Influence of prevention of caffeine citrate on cytokine profile and bronchopulmonary dysplasia in preterm infants with apnea. ( Gao, Z; Han, D; Kou, C; Li, Z; Liu, Z; Wu, W; Zhang, Y, 2020)
"Caffeine therapy for apnea of prematurity did not significantly reduce the combined rate of academic, motor, and behavioral impairments but was associated with a reduced risk of motor impairment in 11-year-old children with very low birth weight."	5.24	Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity: An 11-Year Follow-up of the CAP Randomized Clinical Trial. ( Anderson, PJ; Asztalos, EV; Costantini, L; D'Ilario, J; Davis, PG; Dewey, D; Doyle, LW; Grunau, RE; Moddemann, D; Nelson, H; Ohlsson, A; Roberts, RS; Schmidt, B; Solimano, A; Tin, W, 2017)
" There were no statistical differences in episodes of feed interruption, number of infants with apnea, feed intolerance or diagnosis of sepsis."	5.24	Randomized Controlled Trial of Slow Versus Rapid Enteral Feeding Advancements on the Clinical Outcomes in Very Low Birth Weight Neonates. ( Ahmed, F; Dey, AC; Dey, SK; Hasan, Z; Jahan, I; Mannan, MA; Nahar, N; Shahidullah, M, 2017)
"To evaluate the effectiveness and safety of different doses of caffeine in treatment of primary apnea in preterm infants."	5.22	[Clinical effectiveness of different doses of caffeine for primary apnea in preterm infants]. ( Liu, G; Tian, X; Zhao, Y, 2016)
" This low-cost neuromodulatory procedure has the potential to provide a non-invasive intervention to reduce apnea, bradycardia and intermittent hypoxia in premature neonates."	5.22	Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia. ( Benharash, P; Cordero, DM; Frank, P; Harper, RM; Kesavan, K, 2016)
" The occurrence of apnea, progression of respiratory distress, nose bleeding, and agitation was defined as ventilation failure."	5.20	Response of Preterm Infants to 2 Noninvasive Ventilatory Support Systems: Nasal CPAP and Nasal Intermittent Positive-Pressure Ventilation. ( Brunherotti, MA; Leonardi, KM; Melo, AP; Silveira, CS; Zaia, JE, 2015)
" Apneic events and bradycardia did not occur in the low-dose group; however, there were three episodes of apnea (42."	5.19	A comparative study of two remifentanil doses for procedural pain in ventilated preterm infants: a randomized, controlled study*. ( Choi, JH; Choi, KY; Kim, EK; Kim, HS; Lee, J; Lee, JH; Park, MS; Shin, SH, 2014)
" Recording monitors were used continuously during the next 48 hours to document prolonged apnea and prolonged bradycardia."	5.13	Absence of an increase in cardiorespiratory events after diphtheria-tetanus-acellular pertussis immunization in preterm infants: a randomized, multicenter study. ( Carbone, T; Karamchandani, N; Kelly, D; Kissin, D; McEntire, B; Steinschneider, A; Violaris, K, 2008)
" Secondary outcomes included change in oxygen use and frequency of apnea and bradycardias postextubation."	5.12	Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for Preterm infants. ( Campbell, DM; Kelly, EN; Shah, PS; Shah, V, 2006)
" The most common cause of extubation failure was apnea/bradycardia."	5.10	A randomized, controlled trial comparing two different continuous positive airway pressure systems for the successful extubation of extremely low birth weight infants. ( Aschner, JL; Fuloria, M; Hansell, BJ; Morgan, TM; Murphy, WP; Stefanescu, BM, 2003)
"Fifteen infants, median gestational age at birth 27 weeks (range 24-30), age at study 27 days (12-60), with >/=6 episodes of bradycardia or hypoxaemia/6 h despite serum caffeine levels in the therapeutic range, received doxapram either intravenously (0."	5.09	Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants. ( Bohnhorst, B; Darraj, S; Poets, CF, 1999)
"Preterm infants with a gestational age of <32 weeks and birth weight of <1,500 g were randomized to receive either caffeine or aminophylline treatment for apnea of prematurity."	5.09	Brain hemodynamic changes in preterm infants after maintenance dose caffeine and aminophylline treatment. ( Bertini, G; Dani, C; Martelli, E; Reali, MF; Rubaltelli, FF; Tronchin, M; Wiechmann, L, 2000)
"Controversy exists as to the risk for postoperative apnea in former preterm infants."	5.08	Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. ( Coté, CJ; Downes, JJ; Kurth, CD; Malviya, SV; Warner, LO; Welborn, LG; Zaslavsky, A, 1995)
"To assess if there was any advantage in the prophylactic use of theophylline to prevent apnea in preterms, we treated 56 preterms (Group A) < 34 weeks gestation with theophylline infusion and compared these with 25 age and weight matched preterms (Group B) who received no therapy."	5.07	Prophylactic theophylline infusion for prevention of apnea of prematurity. ( Ashavaid, TF; Merchant, RH; Sakhalkar, VS, 1992)
"To investigate claims that oscillating mattresses reduce apnea of prematurity and improve growth and neurobehavioural development, we performed a randomized clinical trial using a predetermined sample size."	5.06	Randomized clinical trial of an oscillating air mattress in preterm infants: effect on apnea, growth, and development. ( Campbell, D; Saigal, S; Watts, J, 1986)
"5, or (3) apnea associated with a heart rate less than 100 beats per minute that required frequent stimulation (more than 20 episodes during a 16-hour period)."	5.06	Theophylline treatment in the extubation of infants weighing less than 1,250 grams: a controlled trial. ( Ballard, RA; Clyman, RI; Durand, DJ; Goodman, A; Ray, P, 1987)
"19 infants admitted with a diagnosis of infantile apnea who were found to have periodic breathing were given oral theophylline to determine its effect."	5.05	An evaluation of theophylline for idiopathic apnea of infancy. ( Coward, JH; Duffley, LM; Finer, NN; Peters, KL, 1984)
"It has been suggested that idiopathic apnea of prematurity is related to hypoxia from pulmonary instability or an immaturity of central respiratory control mechanisms."	5.04	Apnea of prematurity. Comparative therapeutic effects of cutaneous stimulation and nasal continuous positive airway pressure. ( Fanaroff, AA; Katona, PG; Kattwinkel, J; Klaus, MH; Nearman, HS, 1975)
" It is thanks to the efforts of Barbara Schmidt and the Caffeine for Apnea of Prematurity (CAP) Trial Group that we now have high-quality and reliable data not only on short-term but also long-term outcomes of caffeine use for apnea of prematurity."	4.90	Caffeine for apnea of prematurity: a neonatal success story. ( Bassler, D; Kreutzer, K, 2014)
" Percentage total sleep time (%TST) with respiratory events (isolated apneas, sequential apneas and periodic breathing (PB)) at each study was calculated."	4.31	Developmental consequences of short apneas and periodic breathing in preterm infants. ( Horne, RSC; Nixson, GM; Siriwardhana, LS; Walter, LM; Wong, FY; Yee, AK, 2023)
" The most common milestone sequence was CPAP discontinuation, caffeine discontinuation, thermoregulation, apnea resolution, and full oral feeds."	4.12	Achievement of maturational milestones among very low birth weight infants. ( Ahmad, SM; Fairchild, KD; Sinkin, RA; Slevin, CC; Sullivan, BA, 2022)
"5 million babies born prematurely, and up to 40% of them are babies with low birth weights, highly prone to a multitude of diseases such as Jaundice, Sepsis, Apnea, and other Metabolic disorders."	3.91	Optimizing neural networks for medical data sets: A case study on neonatal apnea prediction. ( Acharya U, D; Lewis U, LES; M, S; Makkithaya, K; Shirwaikar, RD; Srivastava, S, 2019)
"Doxapram is a treatment option for severe apnea of prematurity (AOP)."	3.91	Doxapram Treatment and Diaphragmatic Activity in Preterm Infants. ( de Jongh, FH; de Waal, CG; Hutten, GJ; Kraaijenga, JV; van Kaam, AH, 2019)
"The factors affecting the safety and efficacy of aminophylline use in the treatment of apnea of prematurity (AOP) in the neonatal intensive care unit (NICU) are not clear."	3.91	Factors affecting the efficacy and safety of aminophylline in treatment of apnea of prematurity in neonatal intensive care unit. ( Dong, Z; Lu, X; Lyu, Q; Mao, Y; Miao, C; Ye, C; Yu, L; Zhang, J, 2019)
"346), apnea (OR = 2."	3.88	Retinopathy of Prematurity Among Very Low-Birth-Weight Infants in China: Incidence and Perinatal Risk Factors. ( Mu, D; Qu, Y; Tong, Y; Wu, T; Xia, B; Zhang, L, 2018)
" Sixty percent reported increasing frequency of apnea-bradycardia events following immunization."	3.88	Variability in Immunization Practices for Preterm Infants. ( Creech, B; Edwards, KM; Gopal, SH; Weitkamp, JH, 2018)
"Incidence fell from 74% diagnosed with apnea of prematurity at baseline to 49% diagnosed with CSCPE postimplementation (P<0."	3.85	Clinically significant cardiopulmonary events and the effect of definition standardization on apnea of prematurity management. ( Ahlers-Schmidt, CR; Bloom, BT; Engel, M; Powell, MB, 2017)
"We evaluated the following outcomes: 1) bloodstream infections, 2) culture-negative sepsis, 3) number of sepsis evaluations, and 4) number of significant apnea/bradycardia events comparing odds ratios between 72 hours before and 72 hours after peripherally inserted central venous catheter removal."	3.80	Incidence of catheter-related bloodstream infections in neonates following removal of peripherally inserted central venous catheters. ( Casner, M; Hill, M; Hoesli, SJ; Slaughter, JC; Weitkamp, JH, 2014)
"Three hundred and thirty-eight DBS cards for caffeine measurement were collected from 67 preterm infants (birth weight 0."	3.79	Dried blood spots and sparse sampling: a practical approach to estimating pharmacokinetic parameters of caffeine in preterm infants. ( Della Pasqua, O; Field, DJ; Gade, S; Kairamkonda, V; Mulla, H; Pandya, HC; Patel, P; Spooner, N, 2013)
" Prematurity and perioperative sedation have been shown to be risk factors for postoperative apnea."	3.78	Predictive factors of PACU stay after herniorraphy in infant: a classification and regression tree analysis. ( Brasher, C; Dahmani, S; Julien, F; Mantz, J; Nivoche, Y; Silins, V, 2012)
"This study evaluated the optimal timing for repair, incarceration risk, and postoperative apnea rate in premature infants with inguinal hernias."	3.77	A critical review of premature infants with inguinal hernias: optimal timing of repair, incarceration risk, and postoperative apnea. ( Gleason, JM; Lee, SL; Sydorak, RM, 2011)
"Clinically relevant apneas, which are common in preterm infants, may adversely affect later neuropsychological condition in this group of patients."	3.75	Differential diagnosis of apneas in preterm infants. ( Dittrichová, J; Melichar, J; Miletín, J; Paul, K, 2009)
"001), apnea (P=0."	3.75	Retinopathy of prematurity in a tertiary care center--incidence, risk factors and outcome. ( Chaudhari, S; Kadam, S; Kamat, A; Patwardhan, V; Vaidya, U, 2009)
"Doxapram is a respiratory stimulant widely used for the treatment of idiopathic apnea of prematurity, although it has been demonstrated that it can induce a transient decrease of cerebral blood flow and that isolated mental delay in infants weighing <1,250 g is associated with the total dosage and duration of doxapram therapy."	3.73	Brain hemodynamic effects of doxapram in preterm infants. ( Bertini, G; Dani, C; Filippi, L; Pezzati, M; Pratesi, S; Rubaltelli, FF; Tronchin, M, 2006)
"Adverse cardiorespiratory events including apnea, bradycardia, and desaturations have been described following administration of the first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B (DTP-IPV-Hib) immunization to preterm infants."	3.73	Frequency of apnea, bradycardia, and desaturations following first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B immunization in hospitalized preterm infants. ( Lee, J; Robinson, JL; Spady, DW, 2006)
"Apnea of prematurity develop during the first days of life and usually resolve by the time the infant reaches 36-37 weeks postmenstrual age."	3.73	[Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate]. ( Baudon, JJ; Biran-Mucignat, V; Boelle, PY; Ducrocq, S; Gold, F; Lebas, F, 2006)
"Premature infants need to attain both medical stability and maturational milestones (specifically, independent thermoregulation, resolution of apnea of prematurity, and the ability to feed by mouth) before safe discharge to home."	3.71	Inter-neonatal intensive care unit variation in discharge timing: influence of apnea and feeding management. ( Blackwell, M; Eichenwald, EC; Lloyd, JS; Richardson, DK; Tran, T; Wilker, RE, 2001)
"To identify current factors associated with home apnea monitor use in preterm infants and to determine whether home monitor use was associated with a shorter length of hospital stay."	3.71	Home apnea monitor use in preterm infants discharged from newborn intensive care units. ( Clark, R; Dodd, E; Peabody, J; Perfect Sychowski, S; Thomas, P, 2001)
"Apnea of prematurity is common and none of the treatments being used are fully effective and free of significant adverse side effects."	3.71	Inhalation of low (0.5%-1.5%) CO2 as a potential treatment for apnea of prematurity. ( Al-Aif, S; Alvaro, R; Cates, D; Kwiatkowski, K; Manfreda, J; Rigatto, H, 2001)
" This study was designed to test the hypothesis that recurrent central apneas in preterm infants are correlated with a reduced prostacyclin to thromboxane A2 ratio."	3.70	Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. ( Bernhard, M; Hoch, B, 1999)
"9 seconds central respiratory pauses (RP), the apnea index (AI) [AI=% of nonbreathing time], and the time spent with periodic breathing (PB), as compared with AGA infants."	3.69	Respiratory characteristics during sleep in healthy small-for- gestational age newborns. ( Christova, E; Curzi-Dascalova, L; Peirano, P, 1996)
" Under baseline conditions, prenatal cocaine 1) increased the number of apneas expressed by silence of EMGdi or EMGpca and prolonged the duration of EMGpca-related apneas at both ages; 2) increased the number of periodic breathing episodes at both ages; 3) increased percent time of active sleep and decreased that of wakefulness at both ages; and 4) increased time in quiet sleep in the older animals, producing in them a sleep-wake distribution similar to that of the young neonates."	3.69	Chronic prenatal cocaine retards maturation of state and of respiratory patterns in swine. ( Laferrière, A; Moss, IR, 1995)
" Immaturity at delivery, metabolic acidosis, respiratory distress syndrome and recurrent apnea are important mechanisms of cerebral injury contributing to severity of PVH-IVH."	3.68	Neonatal complications and risk of intraventricular-periventricular hemorrhage. ( Ciarlini, G; Ferrari, B; Luzietti, R; Merialdi, A; Tonni, G; Vadora, E, 1992)
"This research was an exploratory follow-up study of 51 infants who had experienced an "apparent life-threatening event" (ALTE) characterized by apnea and subsequent home cardiorespiratory monitoring."	3.68	Apparent life-threatening events during infancy: a follow-up study of subsequent growth and development. ( Baroni, MA, 1991)
"The occurrence of central apnea of 15 seconds or longer, transient episodes of bradycardia (TEB), and periodic breathing were studied in 66 healthy premature infants when at least 1 week old and between 32 and 36 weeks postconceptual age."	3.68	Apnea, transient episodes of bradycardia, and periodic breathing in preterm infants. ( Cabal, LA; Gonzalez, F; Hodgman, JE; Hoppenbrouwers, T, 1990)
"Recordings of breathing movements and heart rate (pneumograms) were obtained prospectively in 89 preterm infants at 0-28 days of age to determine if those who develop apnea and/or bradycardia with cyanosis (Group 1) differ from those who do not (Group 2)."	3.68	Prospective pneumogram recordings in preterm infants with and without clinical apnea and bradycardia. ( Kelly, DH; McCulloch, KM, 1990)
"Twelve premature infants with significant apnea of prematurity while receiving therapeutic doses of aminophylline were given an intravenous infusion of doxapram, 2 or 2."	3.67	Physiologic effects of doxapram in idiopathic apnea of prematurity. ( Barrington, KJ; Barton, J; Finer, NN; Peters, KL, 1986)
"Apnea, bradycardia, and neuromuscular hyperirritability have been associated with magnesium (Mg) deficiency in young human infants and weanling animals."	3.67	Magnesium therapy in premature neonates with apnea neonatorum. ( Caddell, JL, 1988)
"To determine the relationship of electrocardiographic changes to both intraventricular hemorrhage (IVH) and neonatal apnea, continuous electrocardiographic monitoring, serial electrocardiograms, and cranial echoencephalograms were obtained on 41 consecutive preterm neonates with birth weight below 1,250 g."	3.67	The electrocardiogram in preterm infants with intraventricular hemorrhage and apnea. ( Colavita, RD; Ment, LR, 1986)
"To evaluate the relationship of antecedent maternal smoking and caffeine consumption habits on the occurrence of apnea in their offspring, rates for central and obstructive apnea were analyzed in a cohort of mother-infant pairs."	3.67	Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study. ( Bendell, D; Duke, JC; Mattice, CD; McCaffree, MA; Orr, WC; Toubas, PL, 1986)
" Twelve infants were premature with a history of apnea, eight were premature without known apnea, and 10 were born at term."	3.67	Risk of hypoventilation in premature infants in car seats. ( Leuschen, MP; Nelson, LS; Nelson, RM; Willett, LD, 1986)
"001); apnea requiring bag and mask resuscitation with oxygen (P less than ."	3.66	Risk factors in retrolental fibroplasia. ( Aranda, JV; Easdown, J; Gunn, TR; Outerbridge, EW, 1980)
"The efficacy of theophylline in preventing severe apnea was evaluated in 17 low-birthweight infants (mean weight, 1,400 gm)."	3.65	Prevention of apnea and bradycardia in low-birthweight infants. ( Gotay, F; Moylan, FM; Rogers, MC; Shannon, DC; Stein, IM; Todres, ID, 1975)
" No over-all pattern relating sleep state to frequency of apnea could be detected for individual infants."	3.65	Sleep state, apnea and bradycardia in pre-term infants. ( Auld, PA; Krauss, AN; Solomon, GE, 1977)
" irregular breathing leading to recurrent apnea and bradycardia in an otherwise healthy preterm infant, has been studied in respect of symptomathology and management with intensive case including ventilatory support."	3.65	Respiratory insufficiency syndrome (RIS) in preterm infants with gestational age of 32 weeks and less. Neonatal management and follow-up study. ( Carlsson, J; Svenningsen, NW, 1975)
"To identify dosing strategies that will assure stable caffeine concentrations in preterm neonates despite changing caffeine clearance during the first 8 weeks of life."	1.46	Caffeine Citrate Dosing Adjustments to Assure Stable Caffeine Concentrations in Preterm Neonates. ( Datta, AN; Jost, K; Koch, G; Pfister, M; Schulzke, SM; van den Anker, J, 2017)
"Mean birth weight was lower in the apnoea group versus the breathing group (683 vs."	1.46	Effects of Breathing and Apnoea during Sustained Inflations in Resuscitation of Preterm Infants. ( Bresesti, I; Castoldi, F; Cavigioli, F; La Verde, PA; Lista, G; Morley, CJ, 2017)
"Retinopathy of prematurity was detected in 10."	1.35	Risk factors for retinopathy of prematurity in six neonatal intensive care units in Beijing, China. ( Chen, Y; Gilbert, C; Jiang, YR; Li, XX; Liang, JH; Yin, H; Zhao, MW, 2008)
"Brain abscess and hypoxemia were thought to be serious complications resulting from CAPV and were successfully corrected by living donor liver transplantation at the age of 4 months."	1.33	Successful liver transplantation for congenital absence of the portal vein complicated by intrapulmonary shunt and brain abscess. ( Doi, H; Haga, H; Kamei, H; Kasahara, M; Ogawa, K; Ogura, Y; Ohnishi, Y; Tanaka, K; Ueda, M; Yoshitoshi, EY, 2005)
"Vomiting was present in 4% of the newborns, gastric aspirates in 22% and apnoeas in 41% after the examination."	1.32	Screening for retinopathy of prematurity: is it painful? ( Belda, S; De la Cruz, J; Pallás, CR; Tejada, P, 2004)
"The incidence of sudden infant death syndrome (SIDS) has been found to be consistently higher in preterm and low birth weight infants than in infants born at term and this increase is inversely related to gestational age."	1.31	Apnoea of prematurity and arousal from sleep. ( Adamson, TM; Andrew, S; Chau, B; Cranage, SM; Horne, RS; Mitchell, K; Sly, DJ, 2001)
"The overall incidence of SIDS exceeded that of PIA by a factor of 3."	1.27	Epidemiological comparisons of sudden infant death syndrome with infant apnoea. ( Bossung-Sweeney, L; Davis, N; Peterson, DR, 1986)
"16% from Apnoe and approx."	1.25	[Infants of low birth weight after deliveries, morbidity and mortality (author's transl)]. ( Hohlweg-Majert, P; Kauert, S, 1975)
"Within a three-month period 13 cases of listeriosis in the newborn were seen at the National Women's Hospital, Auckland."	1.25	Epidemic listeriosis in the newborn. ( Becroft, DM; Farmer, K; Seddon, RJ; Sowden, R; Stewart, JH; Vines, A; Wattie, DA, 1971)

Research

Studies (153)

Authors

Clinical Trials (13)

Trial Overview

Trial Outcomes

Change in the Total Number of Bradycardia Episodes (<100 Beats Per Minute (Bpm), at Least 5 Seconds Long) During Intervention and Without the Intervention

Timeframe	Studies, this research(%)	All Research%
pre-1990	83 (54.25)	18.7374
1990's	19 (12.42)	18.2507
2000's	22 (14.38)	29.6817
2010's	25 (16.34)	24.3611
2020's	4 (2.61)	2.80

Authors	Studies
Yee, AK	1
Siriwardhana, LS	1
Nixson, GM	1
Walter, LM	1
Wong, FY	1
Horne, RSC	1
Moresco, L	1
Sjögren, A	1
Marques, KA	1
Soll, R	1
Bruschettini, M	1
Shirwaikar, RD	1
Acharya U, D	1
Makkithaya, K	1
M, S	1
Srivastava, S	1
Lewis U, LES	1
Sullivan, BA	1
Slevin, CC	1
Ahmad, SM	1
Sinkin, RA	1
Fairchild, KD	1
Schmidt, B	1
Roberts, RS	1
Anderson, PJ	1
Asztalos, EV	1
Costantini, L	1
Davis, PG	2
Dewey, D	1
D'Ilario, J	1
Doyle, LW	1
Grunau, RE	1
Moddemann, D	1
Nelson, H	1
Ohlsson, A	1
Solimano, A	1
Tin, W	1
Ahmed, F	1
Mannan, MA	1
Dey, AC	1
Nahar, N	1
Hasan, Z	1
Jahan, I	1
Dey, SK	1
Shahidullah, M	1
Koch, G	1
Datta, AN	1
Jost, K	1
Schulzke, SM	1
van den Anker, J	1
Pfister, M	1
Wu, T	1
Zhang, L	1
Tong, Y	1
Qu, Y	1
Xia, B	1
Mu, D	1
Ye, C	1
Miao, C	1
Yu, L	1
Dong, Z	1
Zhang, J	1
Mao, Y	1
Lu, X	1
Lyu, Q	1
Gopal, SH	1
Edwards, KM	1
Creech, B	1
Weitkamp, JH	2
Oishi, Y	1
Ohta, H	1
Hirose, T	1
Nakaya, S	1
Tsuchiya, K	1
Nakagawa, M	1
Kusakawa, I	1
Sato, T	1
Obonai, T	1
Nishida, H	1
Yoda, H	1
de Waal, CG	1
Hutten, GJ	1
Kraaijenga, JV	1
de Jongh, FH	1
van Kaam, AH	1
Kou, C	1
Han, D	1
Li, Z	1
Wu, W	1
Liu, Z	1
Zhang, Y	1
Gao, Z	1
Casner, M	1
Hoesli, SJ	1
Slaughter, JC	1
Hill, M	1
Shin, SH	1
Kim, HS	1
Lee, J	2
Choi, KY	1
Lee, JH	1
Kim, EK	1
Park, MS	1
Choi, JH	1
Tong, X	1
Xue, X	1
Fu, J	1
Kreutzer, K	1
Bassler, D	1
Silveira, CS	1
Leonardi, KM	1
Melo, AP	1
Zaia, JE	1
Brunherotti, MA	1
Zhao, Y	1
Tian, X	1
Liu, G	1
Budhathoki, S	1
Poudel, P	1
Bhatta, NK	1
Singh, RR	1
Shrivastava, MK	1
Niraula, SR	1
Khanal, B	1
Kesavan, K	1
Frank, P	1
Cordero, DM	1
Benharash, P	1
Harper, RM	1
Reid, B	1
Wang, H	1
Guillet, R	1
Powell, MB	1
Ahlers-Schmidt, CR	1
Engel, M	1
Bloom, BT	1
Lista, G	1
Cavigioli, F	1
La Verde, PA	1
Castoldi, F	1
Bresesti, I	1
Morley, CJ	2
Paul, K	1
Melichar, J	1
Miletín, J	1
Dittrichová, J	1
Shah, PS	2
Perlman, M	1
Pantalitschka, T	1
Sievers, J	1
Urschitz, MS	1
Herberts, T	1
Reher, C	1
Poets, CF	2
Chaudhari, S	1
Patwardhan, V	1
Vaidya, U	1
Kadam, S	1
Kamat, A	1
Nishiura, H	1
Kimura, A	1
Yamato, Y	1
Aoki, K	1
Inokuchi, T	1
Kurosawa, T	1
Matsuishi, T	1
Lee, SL	1
Gleason, JM	1
Sydorak, RM	1
Owen, LS	1
Dawson, JA	1
Silins, V	1
Julien, F	1
Brasher, C	1
Nivoche, Y	1
Mantz, J	1
Dahmani, S	1
Patel, P	1
Mulla, H	1
Kairamkonda, V	1
Spooner, N	1
Gade, S	1
Della Pasqua, O	1
Field, DJ	1
Pandya, HC	1
Stefanescu, BM	1
Murphy, WP	1
Hansell, BJ	1
Fuloria, M	1
Morgan, TM	1
Aschner, JL	1
Wu, XJ	1
Xu, YP	1
Shi, LP	1
Kim, TI	1
Sohn, J	1
Pi, SY	1
Yoon, YH	1
Belda, S	1
Pallás, CR	1
De la Cruz, J	1
Tejada, P	1
Ohnishi, Y	1
Ueda, M	1
Doi, H	1
Kasahara, M	1
Haga, H	1
Kamei, H	1
Ogawa, K	1
Ogura, Y	1
Yoshitoshi, EY	1
Tanaka, K	1
Dani, C	2
Bertini, G	2
Pezzati, M	1
Pratesi, S	1
Filippi, L	1
Tronchin, M	2
Rubaltelli, FF	2
Sale, SM	1
Read, JA	1
Stoddart, PA	1
Wolf, AR	1
Robinson, JL	1
Spady, DW	1
Campbell, DM	1
Shah, V	1
Kelly, EN	1
Ducrocq, S	1
Biran-Mucignat, V	1
Boelle, PY	1
Lebas, F	1
Baudon, JJ	1
Gold, F	1
Chen, Y	1
Li, XX	1
Yin, H	1
Gilbert, C	1
Liang, JH	1
Jiang, YR	1
Zhao, MW	1
Carbone, T	1
McEntire, B	1
Kissin, D	1
Kelly, D	1
Steinschneider, A	1
Violaris, K	1
Karamchandani, N	1
Creery, RD	1
Waugh, R	1
Johnson, GG	1
Thompson, RG	1
Finer, NN	2
Peters, KL	2
Duffley, LM	1
Coward, JH	1
Flynn, JT	1
Gunn, TR	2
Easdown, J	1
Outerbridge, EW	1
Aranda, JV	1
Lagercrantz, H	1
Sjöquist, B	1
Rossiter, EJ	1
Moss, IR	1
Laferrière, A	1
Coté, CJ	1
Zaslavsky, A	1
Downes, JJ	1
Kurth, CD	1
Welborn, LG	1
Warner, LO	1
Malviya, SV	1
Svenningsen, NW	2
Wittström, C	1
Hellström-Westas, L	1
Curzi-Dascalova, L	1
Peirano, P	1
Christova, E	1
Claris, O	1
Salle, BL	1
Lapillonne, A	1
Ronin, E	1
Picaud, JC	1
Besnier, S	1
Rehan, VK	1
Fajardo, CA	1
Haider, AZ	1
Alvaro, RE	1
Cates, DB	1
Kwiatkowski, K	2
Nowaczyk, B	1
Rigatto, H	4
al-Omran, A	1
al-Alaiyan, S	1
Botham, SJ	1
Isaacs, D	1
Henderson-Smart, DJ	1
da Silva, O	1
Stevens, D	1
Darraj, S	1
Bohnhorst, B	1
Hoch, B	1
Bernhard, M	1
Tonkin, SL	1
Hadden, W	1
Davis, SL	1
Gunn, AJ	1
Reali, MF	1
Wiechmann, L	1
Martelli, E	1
Horne, RS	1
Andrew, S	1
Mitchell, K	1
Sly, DJ	1
Cranage, SM	1
Chau, B	1
Adamson, TM	1
Al-Aif, S	1
Alvaro, R	1
Manfreda, J	1
Cates, D	1
Perfect Sychowski, S	1
Dodd, E	1
Thomas, P	1
Peabody, J	1
Clark, R	1
Eichenwald, EC	1
Blackwell, M	1
Lloyd, JS	1
Tran, T	1
Wilker, RE	1
Richardson, DK	1
Speidel, BD	2
Dunn, PM	2
Krauss, AN	2
Solomon, GE	1
Auld, PA	2
Shannon, DC	1
Gotay, F	1
Stein, IM	1
Rogers, MC	1
Todres, ID	1
Moylan, FM	1
Jones, MD	1
Murton, LJ	1
Valdes-Dapena, M	1
Kendeel, SR	1
Ferris, JA	1
Friis-Hansen, B	2
Lou, HC	1
Marstrand-Christiansen, P	1
Scheibel, E	1
McDiarmid, JM	1
Silva, PA	1
Eisenberg, W	1
Holzgraefe, E	1
Naim, M	1
Fitzhardinge, PM	2
Pape, P	1
Arstikaitis, M	1
Boyle, M	1
Ashby, S	1
Rowley, A	1
Netley, C	1
Swyer, PR	3
Assael, BM	1
Caccamo, ML	1
Gerna, M	1
Latini, R	1
Mandelli, M	1
Marini, A	1
Sereni, F	1
Tognoni, G	1
Fich, CF	1
Frederiksen, PS	1
Kamper, J	1
Hodr, R	1
Nikl, J	1
Pawlowski, P	1
Venzmer, J	1
Wiedersberg, H	1
Kattwinkel, J	1
Nearman, HS	1
Fanaroff, AA	1
Katona, PG	1
Klaus, MH	1
Coran, AG	1
Cabal, L	1
Siassi, B	1
Rosenkrantz, JG	1
Hasselmeyer, EG	1
Hunter, JC	1
Carlsson, J	1
Roberton, NR	1
Smith, MA	1
Hohlweg-Majert, P	1
Kauert, S	1
Ferrari, B	1
Tonni, G	1
Luzietti, R	1
Ciarlini, G	1
Vadora, E	1
Merialdi, A	1
Merchant, RH	1
Sakhalkar, VS	1
Ashavaid, TF	1
Palme-Kilander, C	1
Baroni, MA	1
Tashiro, C	1
Matsui, Y	1
Nakano, S	1
Ueyama, H	1
Nishimura, M	1
Oka, N	1
Hodgman, JE	1
Gonzalez, F	1
Hoppenbrouwers, T	1
Cabal, LA	1
McCulloch, KM	1
Kelly, DH	1
Kishan, J	1
Valdez, ME	1
Mir, NA	1
Elzouki, AY	1
Purohit, DM	1
Ellison, RC	1
Zierler, S	1
Miettinen, OS	1
Nadas, AS	1
Hoffman, HJ	1
Damus, K	1
Hillman, L	1
Krongrad, E	1
Barrington, KJ	1
Barton, J	1
Durand, DJ	1
Goodman, A	1
Ray, P	1
Ballard, RA	1
Clyman, RI	1
Caddell, JL	1
Saigal, S	1
Watts, J	1
Campbell, D	1
Okoro, BA	1
Okeahialam, TC	1
Colavita, RD	1
Ment, LR	1
Toubas, PL	1
Duke, JC	1
McCaffree, MA	1
Mattice, CD	1
Bendell, D	1
Orr, WC	1
Willett, LD	1
Leuschen, MP	1
Nelson, LS	1
Nelson, RM	1
Davis, JM	1
Abbasi, S	1
Spitzer, AR	1
Johnson, L	1
Davis, N	1
Bossung-Sweeney, L	1
Peterson, DR	1
Keenan, WJ	1
Novak, KK	1
Sutherland, JM	2
Bryla, DA	1
Fetterly, KL	1
Wilkinson, A	1
Yu, VY	1
Reid, DH	1
Higgs, SC	1
Malan, AF	1
De Heese, HV	1
Steele, RW	1
Copeland, GA	1
Fenner, A	1
Schalk, U	1
Hoenicke, H	1
Wendenburg, A	1
Roehling, T	1
Beckwith, JB	1
Stewart, AL	1
Reynolds, EO	2
Francis-Williams, J	1
Davies, PA	1
Rosegger, H	1
Buckfield, PM	1
Alden, ER	2
Mandelkorn, T	1
Woodrum, DE	1
Wennberg, RP	1
Parks, CR	1
Hodson, WA	2
Riegel, K	1
Welsch, H	1
Tori, CA	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Efficacy and Safety of Methylxanthines in Very Low Birthweight Infants[NCT00182312]	Phase 3	2,000 participants (Anticipated)	Interventional	1999-10-31	Completed
Pharmacokinetics (PK) and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia[NCT05295784]	Phase 1	18 participants (Anticipated)	Interventional	2024-06-30	Not yet recruiting
High Versus Low Dose Caffeine as Respiratory Stimulant in Preterm Infants[NCT04144712]	Phase 1	80 participants (Anticipated)	Interventional	2019-04-01	Recruiting
WAVE Trial in Premature Infants With Apnea of Prematurity Using a Simple, Non-invasive Vibratory Device to Study the Effectiveness in Supporting Breathing and General Stability[NCT04528030]		17 participants (Anticipated)	Interventional	2021-04-01	Not yet recruiting
Neuromodulation of Limb Proprioceptive Afferents Using a Vibratory Device to Decrease Apnea, Intermittent Hypoxia and Bradycardia of Prematurity.[NCT02641249]		19 participants (Actual)	Interventional	2014-10-31	Completed
Integrated Prediction of Extubation Outcome by the Spontaneous Breathing Trial in Newborn Infants[NCT03956511]		46 participants (Actual)	Observational	2016-02-29	Completed
Utility of Spontaneous Breathing Trial (SBT) Using ET-CPAP, in Predicting Extubation Failure in Neonates[NCT03091387]		110 participants (Anticipated)	Observational	2017-04-30	Not yet recruiting
Efficiency and Safety of Phenylephrine and Tropicamide Used in Premature Retinopathy[NCT03448640]		60 participants (Actual)	Observational	2016-01-15	Completed
Comparison of Humidified High Flow Nasal Cannula to Nasal Continuous Positive Airway Pressure for Non-Invasive Respiratory Support in Neonates[NCT00609882]		420 participants (Actual)	Interventional	2007-12-31	Completed
Adaptive Dynamic Inspiratory Nasal Apparatus (ADINA): Comparison to High Flow Nasal Cannula (HFNC)[NCT03171129]		40 participants (Anticipated)	Interventional	2024-01-31	Not yet recruiting
Prolonged Apnea and Prolonged Bradycardia Following DTaP Immunization in Preterm Infants: A Randomized Multicenter Study[NCT00482781]		191 participants (Actual)	Interventional	2000-09-30	Completed
A Prospective, Controlled Trial of Inhalation of Low Concentration of CO2 in Preterm Infants Not Responding to Caffeine for the Treatment of Apnea of Prematurity[NCT01911182]	Phase 2/Phase 3	7 participants (Actual)	Interventional	2011-10-31	Terminated (stopped due to Low recruitment rate)
[NCT01066728]	Phase 2/Phase 3	87 participants (Actual)	Interventional	2001-08-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

The total number of bradycardia episodes to <100 bpm lasting >5 seconds/episode will be compared during periods of vibration (intervention) to periods of no vibrations (no intervention). (NCT02641249)
Timeframe: 12 hours of intervention/12 hours of no intervention

Change in the Total Number of Intermittent Hypoxic Episodes to <90% Lasting >5 Seconds/Episode During the Intervention and Without Intervention

Intervention	bradycardias (Mean)
No Vibration	50.53
Vibration	14.93

The total number of intermittent hypoxic episodes to <90% (pulse oximetry) lasting >5 seconds/episode will be compared during periods of vibration (intervention) to periods of no vibrations (no intervention). (NCT02641249)
Timeframe: 12 hours of intervention/12 hours of no intervention

Change in Total Number of Episodes of Apnea/Breathing Pauses During Intervention and Without Intervention

Intervention	IH events (Mean)
No Vibration	151.67
Vibration	109.67

The total number of apneas/breathing pauses will be compared during periods of vibration (intervention) to periods of no vibrations (no intervention). (NCT02641249)
Timeframe: 12 hours of intervention/12 hours of no intervention

Article	Year
Caffeine versus other methylxanthines for the prevention and treatment of apnea in preterm infants. The Cochrane database of systematic reviews, 2023, 10-04, Volume: 10 Topics: Aminophylline; Apnea; Birth Weight; Bronchopulmonary Dysplasia; Caffeine; Hearing Loss; Humans; Infa	2023
Caffeine for apnea of prematurity: a neonatal success story. Neonatology, 2014, Volume: 105, Issue:4 Topics: Animals; Apnea; Birth Weight; Caffeine; Cost-Benefit Analysis; Drug Costs; Gestational Age; Humans;	2014
Hyperventilation, hypokalemia, and SIDS. Hospital practice (Office ed.), 1984, Volume: 19, Issue:12 Topics: Apnea; Birth Weight; Carbon Dioxide; Chemoreceptor Cells; Depression; Diaphragm; Dietary Carbohydrat	1984
The Geelong study. Acta paediatrica (Oslo, Norway : 1992). Supplement, 1993, Volume: 82 Suppl 392 Topics: Apnea; Birth Weight; Child; Child Behavior Disorders; Child, Preschool; Delivery, Obstetric; Develop	1993
Mechanical ventilation in newborn infants with hyaline membrane disease;. Pediatric annals, 1977, Volume: 6, Issue:4 Topics: Acidosis; Apnea; Birth Weight; Bradycardia; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Gestatio	1977
Sudden unexplained infant death, 1970 through 1975 an evolution in understanding. Pathology annual, 1977, Volume: 12 Pt 1 Topics: Age Factors; Antibodies; Apnea; Birth Order; Birth Weight; Environment; Female; Humans; Illegitimacy	1977
Sudden infant death syndrome: a review of literature. Journal - Forensic Science Society, 1977, Volume: 17, Issue:4 Topics: Agammaglobulinemia; Animals; Apnea; Asphyxia; Birth Weight; Food Hypersensitivity; Humans; Infant; I	1977
The sudden infant death syndrome. Obstetrics and gynecology annual, 1975, Volume: 4 Topics: Age Factors; Antibody Formation; Apnea; Asphyxia; Autonomic Nervous System; Birth Weight; Female; Ge	1975
Risk factors for SIDS. Results of the National Institute of Child Health and Human Development SIDS Cooperative Epidemiological Study. Annals of the New York Academy of Sciences, 1988, Volume: 533 Topics: Apnea; Birth Weight; Diarrhea, Infantile; Female; Humans; Infant; Infant, Newborn; Jaundice, Neonata	1988
The sudden infant death syndrome. Current problems in pediatrics, 1973, Volume: 3, Issue:8 Topics: Age Factors; Anaphylaxis; Apnea; Asphyxia; Autopsy; Birth Weight; Counseling; Death, Sudden; Feeding	1973
[Urgent care for the high-risk newborn infant]. Zeitschrift fur Geburtshilfe und Perinatologie, 1973, Volume: 177, Issue:1 Topics: Apgar Score; Apnea; Birth Weight; Blood Transfusion; Edema; Erythroblastosis, Fetal; Female; Humans;	1973

Article	Year
Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity: An 11-Year Follow-up of the CAP Randomized Clinical Trial. JAMA pediatrics, 2017, 06-01, Volume: 171, Issue:6 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Child Behavior Disorders; Child De	2017
Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity: An 11-Year Follow-up of the CAP Randomized Clinical Trial. JAMA pediatrics, 2017, 06-01, Volume: 171, Issue:6 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Child Behavior Disorders; Child De	2017
Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity: An 11-Year Follow-up of the CAP Randomized Clinical Trial. JAMA pediatrics, 2017, 06-01, Volume: 171, Issue:6 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Child Behavior Disorders; Child De	2017
Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity: An 11-Year Follow-up of the CAP Randomized Clinical Trial. JAMA pediatrics, 2017, 06-01, Volume: 171, Issue:6 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Child Behavior Disorders; Child De	2017
Randomized Controlled Trial of Slow Versus Rapid Enteral Feeding Advancements on the Clinical Outcomes in Very Low Birth Weight Neonates. Mymensingh medical journal : MMJ, 2017, Volume: 26, Issue:2 Topics: Apnea; Birth Weight; Enteral Nutrition; Food Intolerance; Humans; Infant; Infant, Newborn; Infant, V	2017
Influence of prevention of caffeine citrate on cytokine profile and bronchopulmonary dysplasia in preterm infants with apnea. Minerva pediatrica, 2020, Volume: 72, Issue:2 Topics: Apnea; Birth Weight; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Citrat	2020
A comparative study of two remifentanil doses for procedural pain in ventilated preterm infants: a randomized, controlled study. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014, Volume: 15, Issue:5* Topics: Analgesics, Opioid; Apnea; Birth Weight; Bradycardia; Catheterization, Central Venous; Double-Blind	2014
Response of Preterm Infants to 2 Noninvasive Ventilatory Support Systems: Nasal CPAP and Nasal Intermittent Positive-Pressure Ventilation. Respiratory care, 2015, Volume: 60, Issue:12 Topics: Apnea; Birth Weight; Continuous Positive Airway Pressure; Disease Progression; Epistaxis; Female; Ge	2015
[Clinical effectiveness of different doses of caffeine for primary apnea in preterm infants]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2016, Volume: 54, Issue:1 Topics: Apnea; Birth Weight; Caffeine; Citrates; Female; Gestational Age; Humans; Infant, Newborn; Infant, P	2016
Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia. PloS one, 2016, Volume: 11, Issue:6 Topics: Afferent Pathways; Apnea; Birth Weight; Bradycardia; Extremities; Female; Gestational Age; Humans; H	2016
Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia. PloS one, 2016, Volume: 11, Issue:6 Topics: Afferent Pathways; Apnea; Birth Weight; Bradycardia; Extremities; Female; Gestational Age; Humans; H	2016
Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia. PloS one, 2016, Volume: 11, Issue:6 Topics: Afferent Pathways; Apnea; Birth Weight; Bradycardia; Extremities; Female; Gestational Age; Humans; H	2016
Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia. PloS one, 2016, Volume: 11, Issue:6 Topics: Afferent Pathways; Apnea; Birth Weight; Bradycardia; Extremities; Female; Gestational Age; Humans; H	2016
Randomised crossover trial of four nasal respiratory support systems for apnoea of prematurity in very low birthweight infants. Archives of disease in childhood. Fetal and neonatal edition, 2009, Volume: 94, Issue:4 Topics: Apnea; Birth Weight; Continuous Positive Airway Pressure; Cross-Over Studies; Female; Gestational Ag	2009
A randomized, controlled trial comparing two different continuous positive airway pressure systems for the successful extubation of extremely low birth weight infants. Pediatrics, 2003, Volume: 112, Issue:5 Topics: Apnea; Birth Weight; Bradycardia; Cohort Studies; Female; Humans; Incidence; Infant, Newborn; Infant	2003
A randomized, controlled trial comparing two different continuous positive airway pressure systems for the successful extubation of extremely low birth weight infants. Pediatrics, 2003, Volume: 112, Issue:5 Topics: Apnea; Birth Weight; Bradycardia; Cohort Studies; Female; Humans; Incidence; Infant, Newborn; Infant	2003
A randomized, controlled trial comparing two different continuous positive airway pressure systems for the successful extubation of extremely low birth weight infants. Pediatrics, 2003, Volume: 112, Issue:5 Topics: Apnea; Birth Weight; Bradycardia; Cohort Studies; Female; Humans; Incidence; Infant, Newborn; Infant	2003
A randomized, controlled trial comparing two different continuous positive airway pressure systems for the successful extubation of extremely low birth weight infants. Pediatrics, 2003, Volume: 112, Issue:5 Topics: Apnea; Birth Weight; Bradycardia; Cohort Studies; Female; Humans; Incidence; Infant, Newborn; Infant	2003
Prospective comparison of sevoflurane and desflurane in formerly premature infants undergoing inguinal herniotomy. British journal of anaesthesia, 2006, Volume: 96, Issue:6 Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Apnea; Birth Weight; Desflurane; Gestational Ag	2006
Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for Preterm infants. Journal of perinatology : official journal of the California Perinatal Association, 2006, Volume: 26, Issue:9 Topics: Apnea; Birth Weight; Catheterization; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prem	2006
Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for Preterm infants. Journal of perinatology : official journal of the California Perinatal Association, 2006, Volume: 26, Issue:9 Topics: Apnea; Birth Weight; Catheterization; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prem	2006
Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for Preterm infants. Journal of perinatology : official journal of the California Perinatal Association, 2006, Volume: 26, Issue:9 Topics: Apnea; Birth Weight; Catheterization; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prem	2006
Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for Preterm infants. Journal of perinatology : official journal of the California Perinatal Association, 2006, Volume: 26, Issue:9 Topics: Apnea; Birth Weight; Catheterization; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prem	2006
Absence of an increase in cardiorespiratory events after diphtheria-tetanus-acellular pertussis immunization in preterm infants: a randomized, multicenter study. Pediatrics, 2008, Volume: 121, Issue:5 Topics: Apnea; Birth Weight; Bradycardia; Diphtheria-Tetanus-acellular Pertussis Vaccines; Double-Blind Meth	2008
An evaluation of theophylline for idiopathic apnea of infancy. Developmental pharmacology and therapeutics, 1984, Volume: 7, Issue:2 Topics: Apnea; Birth Weight; Clinical Trials as Topic; Humans; Infant; Infant, Newborn; Infant, Premature, D	1984
Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. Anesthesiology, 1995, Volume: 82, Issue:4 Topics: Aging; Analysis of Variance; Anemia; Anesthesia; Apnea; Birth Weight; Hernia, Inguinal; Humans; Infa	1995
Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants. Biology of the neonate, 1999, Volume: 76, Issue:4 Topics: Apnea; Birth Weight; Bradycardia; Caffeine; Doxapram; Drug Resistance; Gestational Age; Humans; Hypo	1999
Brain hemodynamic changes in preterm infants after maintenance dose caffeine and aminophylline treatment. Biology of the neonate, 2000, Volume: 78, Issue:1 Topics: Aminophylline; Apnea; Birth Weight; Blood Flow Velocity; Blood Volume; Caffeine; Central Nervous Sys	2000
Apnea of prematurity. Comparative therapeutic effects of cutaneous stimulation and nasal continuous positive airway pressure. The Journal of pediatrics, 1975, Volume: 86, Issue:4 Topics: Apnea; Birth Weight; Cyanosis; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases	1975
Prophylactic theophylline infusion for prevention of apnea of prematurity. Indian pediatrics, 1992, Volume: 29, Issue:11 Topics: Aminophylline; Apnea; Birth Weight; Humans; Infant, Newborn; Infant, Premature, Diseases; Infusions,	1992
Theophylline treatment in the extubation of infants weighing less than 1,250 grams: a controlled trial. Pediatrics, 1987, Volume: 80, Issue:5 Topics: Apnea; Birth Weight; Body Weight; Clinical Trials as Topic; Humans; Infant, Low Birth Weight; Infant	1987
Randomized clinical trial of an oscillating air mattress in preterm infants: effect on apnea, growth, and development. The Journal of pediatrics, 1986, Volume: 109, Issue:5 Topics: Air; Apnea; Beds; Birth Weight; Body Weight; Bradycardia; Child Behavior; Child Development; Clinica	1986
A comparison of oral feeding and total parenteral nutrition in infants of very low birthweight. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Oct-26, Volume: 48, Issue:52 Topics: Amino Acids; Apnea; Birth Weight; Cholesterol; Clinical Trials as Topic; Enteral Nutrition; Female;	1974
Oxygen chemoreceptors in low birth weight infants. Pediatric research, 1973, Volume: 7, Issue:6 Topics: Age Factors; Altitude; Apnea; Atmospheric Pressure; Birth Weight; Chemoreceptor Cells; Clinical Tria	1973
Supplemental intravenous alimentation in low-birth-weight infants. The Journal of pediatrics, 1973, Volume: 82, Issue:6 Topics: Amino Acids; Apnea; Birth Weight; Blood Glucose; Body Weight; Chromatography, Thin Layer; Fibrin; Ge	1973

Article	Year
Developmental consequences of short apneas and periodic breathing in preterm infants. Journal of perinatology : official journal of the California Perinatal Association, 2023, Volume: 43, Issue:11 Topics: Apnea; Birth Weight; Child; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Inf	2023
Optimizing neural networks for medical data sets: A case study on neonatal apnea prediction. Artificial intelligence in medicine, 2019, Volume: 98 Topics: Algorithms; Apnea; Birth Weight; Clinical Decision Rules; Datasets as Topic; Decision Trees; Deep Le	2019
Achievement of maturational milestones among very low birth weight infants. Journal of neonatal-perinatal medicine, 2022, Volume: 15, Issue:1 Topics: Apnea; Birth Weight; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Infant, Very Low	2022
Caffeine Citrate Dosing Adjustments to Assure Stable Caffeine Concentrations in Preterm Neonates. The Journal of pediatrics, 2017, Volume: 191 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Citrates; Dose-Response Relationsh	2017
Retinopathy of Prematurity Among Very Low-Birth-Weight Infants in China: Incidence and Perinatal Risk Factors. Investigative ophthalmology & visual science, 2018, 02-01, Volume: 59, Issue:2 Topics: Apnea; Birth Weight; Blood Transfusion; Bronchopulmonary Dysplasia; China; Ductus Arteriosus, Patent	2018
Factors affecting the efficacy and safety of aminophylline in treatment of apnea of prematurity in neonatal intensive care unit. Pediatrics and neonatology, 2019, Volume: 60, Issue:1 Topics: Aminophylline; Apnea; Birth Weight; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant	2019
Variability in Immunization Practices for Preterm Infants. American journal of perinatology, 2018, Volume: 35, Issue:14 Topics: Apnea; Birth Weight; Bradycardia; Gestational Age; Humans; Immunization Schedule; Infant; Infant, Lo	2018
Combined effects of body position and sleep status on the cardiorespiratory stability of near-term infants. Scientific reports, 2018, 06-11, Volume: 8, Issue:1 Topics: Apnea; Birth Weight; Bradycardia; Female; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Prema	2018
Doxapram Treatment and Diaphragmatic Activity in Preterm Infants. Neonatology, 2019, Volume: 115, Issue:1 Topics: Apnea; Birth Weight; Diaphragm; Doxapram; Electromyography; Female; Gestational Age; Humans; Infant,	2019
Incidence of catheter-related bloodstream infections in neonates following removal of peripherally inserted central venous catheters. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014, Volume: 15, Issue:1 Topics: Anti-Bacterial Agents; Apnea; Birth Weight; Bradycardia; Catheter-Related Infections; Catheterizatio	2014
[Exploring the clinical significance of continuously measuring apparent diffusion coefficient values in the preterm infants with punctate white matter damage by applying diffusion weighted imaging]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2014, Volume: 52, Issue:4 Topics: Apnea; Birth Weight; Brain; Brain Diseases; Case-Control Studies; Diffusion Magnetic Resonance Imagi	2014
Clinico-epidemiological study of low birth weight newborns in the Eastern part of Nepal. Nepal Medical College journal : NMCJ, 2014, Volume: 16, Issue:2-4 Topics: Apnea; Birth Weight; Female; Fetal Growth Retardation; Gestational Age; Gravidity; Humans; Incidence	2014
Apnea after Routine Eye Examinations in Premature Infants. American journal of perinatology, 2017, Volume: 34, Issue:2 Topics: Apnea; Birth Weight; Bradycardia; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Ophth	2017
Clinically significant cardiopulmonary events and the effect of definition standardization on apnea of prematurity management. Journal of perinatology : official journal of the California Perinatal Association, 2017, Volume: 37, Issue:1 Topics: Apnea; Birth Weight; Caffeine; Disease Management; Female; Gestational Age; Humans; Infant; Infant,	2017
Effects of Breathing and Apnoea during Sustained Inflations in Resuscitation of Preterm Infants. Neonatology, 2017, Volume: 111, Issue:4 Topics: Apnea; Birth Weight; Delivery Rooms; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prema	2017
Differential diagnosis of apneas in preterm infants. European journal of pediatrics, 2009, Volume: 168, Issue:2 Topics: Apgar Score; Apnea; Arousal; Birth Weight; Diagnosis, Differential; Electrocardiography; Electroence	2009
Time courses of intrapartum asphyxia: neonatal characteristics and outcomes. American journal of perinatology, 2009, Volume: 26, Issue:1 Topics: Acidosis; Apgar Score; Apnea; Asphyxia Neonatorum; Birth Weight; Cause of Death; Child, Preschool; C	2009
Retinopathy of prematurity in a tertiary care center--incidence, risk factors and outcome. Indian pediatrics, 2009, Volume: 46, Issue:3 Topics: Apnea; Birth Weight; Developing Countries; Female; Gestational Age; Humans; Incidence; India; Infant	2009
Developmental pattern of urinary bile acid profile in preterm infants. Pediatrics international : official journal of the Japan Pediatric Society, 2010, Volume: 52, Issue:1 Topics: Apgar Score; Apnea; Bile Acids and Salts; Birth Weight; Female; Gas Chromatography-Mass Spectrometry	2010
A critical review of premature infants with inguinal hernias: optimal timing of repair, incarceration risk, and postoperative apnea. Journal of pediatric surgery, 2011, Volume: 46, Issue:1 Topics: Apnea; Birth Weight; Comorbidity; Elective Surgical Procedures; Female; General Surgery; Gestational	2011
Effects of non-synchronised nasal intermittent positive pressure ventilation on spontaneous breathing in preterm infants. Archives of disease in childhood. Fetal and neonatal edition, 2011, Volume: 96, Issue:6 Topics: Apnea; Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Pr	2011
Predictive factors of PACU stay after herniorraphy in infant: a classification and regression tree analysis. Paediatric anaesthesia, 2012, Volume: 22, Issue:3 Topics: Analgesics; Anesthesia, General; Anesthesia, Spinal; Apnea; Birth Weight; Cohort Studies; Conscious	2012
Dried blood spots and sparse sampling: a practical approach to estimating pharmacokinetic parameters of caffeine in preterm infants. British journal of clinical pharmacology, 2013, Volume: 75, Issue:3 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Agents; Dried Blood Spot Testing; Female; Gest	2013
[Analysis of apnea in 229 cases of very low birth weight infants]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:8 Topics: Apnea; Birth Weight; China; Female; Gestational Age; Humans; Infant, Newborn; Infant, Very Low Birth	2003
Postnatal risk factors of retinopathy of prematurity. Paediatric and perinatal epidemiology, 2004, Volume: 18, Issue:2 Topics: Apnea; Birth Weight; Disease Progression; Gestational Age; Humans; Infant, Newborn; Infant, Prematur	2004
Screening for retinopathy of prematurity: is it painful? Biology of the neonate, 2004, Volume: 86, Issue:3 Topics: Apnea; Birth Weight; Blood Pressure; Diagnostic Techniques, Ophthalmological; Gestational Age; Heart	2004
Successful liver transplantation for congenital absence of the portal vein complicated by intrapulmonary shunt and brain abscess. Journal of pediatric surgery, 2005, Volume: 40, Issue:5 Topics: Abnormalities, Multiple; Anti-Bacterial Agents; Apnea; Atrophy; Birth Weight; Brain; Brain Abscess;	2005
Brain hemodynamic effects of doxapram in preterm infants. Biology of the neonate, 2006, Volume: 89, Issue:2 Topics: Apnea; Birth Weight; Blood Flow Velocity; Brain; Case-Control Studies; Doxapram; Gestational Age; Hu	2006
Frequency of apnea, bradycardia, and desaturations following first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B immunization in hospitalized preterm infants. BMC pediatrics, 2006, Jun-19, Volume: 6 Topics: Alberta; Apnea; Birth Weight; Body Weight; Bradycardia; Child, Hospitalized; Cohort Studies; Diphthe	2006
[Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:10 Topics: Ambulatory Care; Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Citrates; Continu	2006
Risk factors for retinopathy of prematurity in six neonatal intensive care units in Beijing, China. The British journal of ophthalmology, 2008, Volume: 92, Issue:3 Topics: Abruptio Placentae; Anemia; Apnea; Birth Weight; China; Female; Gestational Age; Humans; Hypoxia-Isc	2008
Hypoglycaemia in the newborn: diagnosis, treatment and prognosis. Developmental medicine and child neurology, 1966, Volume: 8, Issue:6 Topics: Apnea; Birth Injuries; Birth Weight; Cyanosis; Female; Glucose; Humans; Hydrocortisone; Hypoglycemia	1966
Current considerations in neonatal anaesthesia. Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:6 Topics: Anesthesia; Anesthetics; Apgar Score; Apnea; Birth Weight; Cardiovascular System; Central Nervous Sy	1984
Acute proliferative retrolental fibroplasia: multivariate risk analysis. Transactions of the American Ophthalmological Society, 1983, Volume: 81 Topics: Analysis of Variance; Anemia; Apnea; Birth Weight; Bronchopulmonary Dysplasia; Cerebral Hemorrhage;	1983
Risk factors in retrolental fibroplasia. Pediatrics, 1980, Volume: 65, Issue:6 Topics: Apnea; Birth Weight; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Infant, Newborn, D	1980
Deficient sympatho-adrenal activity-a cause of apnoea? Urinary excretion of catecholamines and their metabolites in preterm infants. Early human development, 1980, Volume: 4, Issue:4 Topics: Adrenal Glands; Apnea; Birth Weight; Catecholamines; Epinephrine; Gestational Age; Humans; Infant, N	1980
Chronic prenatal cocaine retards maturation of state and of respiratory patterns in swine. Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 79, Issue:2 Topics: Animals; Apnea; Birth Weight; Blood Gas Analysis; Body Temperature; Body Weight; Cocaine; Electroenc	1995
OSCILLO-oscillating air mattress in neonatal care of very preterm babies. Technology and health care : official journal of the European Society for Engineering and Medicine, 1995, Volume: 3, Issue:1 Topics: Air; Apnea; Bedding and Linens; Birth Weight; Gestational Age; Humans; Infant, Newborn; Infant, Prem	1995
Respiratory characteristics during sleep in healthy small-for- gestational age newborns. Pediatrics, 1996, Volume: 97, Issue:4 Topics: Apnea; Birth Weight; Brain Stem; Cerebrovascular Circulation; Fetal Growth Retardation; Gestational	1996
[New technique of nasal continuous positive pressure in neonatology]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1996, Volume: 3, Issue:5 Topics: Apnea; Birth Weight; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Nose; Positive-Pre	1996
Influence of sleep state and respiratory pattern on cyclical fluctuations of cerebral blood flow velocity in healthy preterm infants. Biology of the neonate, 1996, Volume: 69, Issue:6 Topics: Apnea; Birth Weight; Blood Flow Velocity; Cerebrovascular Circulation; Gestational Age; Humans; Infa	1996
Theophylline concentration following equal doses of intravenous aminophylline and oral theophylline in preterm infants. American journal of perinatology, 1997, Volume: 14, Issue:3 Topics: Administration, Oral; Aminophylline; Apnea; Birth Weight; Bronchodilator Agents; Gestational Age; Hu	1997
Incidence of apnoea and bradycardia in preterm infants following DTPw and Hib immunization: a prospective study. Journal of paediatrics and child health, 1997, Volume: 33, Issue:5 Topics: Apnea; Birth Weight; Bradycardia; Diphtheria-Tetanus-Pertussis Vaccine; Female; Haemophilus Vaccines	1997
Complications of airway management in very-low-birth-weight infants. Biology of the neonate, 1999, Volume: 75, Issue:1 Topics: Adrenal Cortex Hormones; Airway Obstruction; Apnea; Birth Weight; Bradycardia; Bronchopulmonary Dysp	1999
Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. Prostaglandins & other lipid mediators, 1999, Volume: 58, Issue:5-6 Topics: 6-Ketoprostaglandin F1 alpha; Apnea; Birth Weight; Epoprostenol; Gestational Age; Humans; Infant, Ne	1999
Neonatal micrognathia is associated with small upper airways on radiographic measurement. Acta paediatrica (Oslo, Norway : 1992), 2000, Volume: 89, Issue:1 Topics: Apnea; Birth Weight; Craniofacial Abnormalities; Data Interpretation, Statistical; Gestational Age;	2000
Apnoea of prematurity and arousal from sleep. Early human development, 2001, Volume: 61, Issue:2 Topics: Apnea; Arousal; Birth Weight; Electrocardiography; Electroencephalography; Electromyography; Electro	2001
Inhalation of low (0.5%-1.5%) CO2 as a potential treatment for apnea of prematurity. Seminars in perinatology, 2001, Volume: 25, Issue:2 Topics: Administration, Inhalation; Apnea; Birth Weight; Carbon Dioxide; Gestational Age; Humans; Infant, Ne	2001
Inhalation of low (0.5%-1.5%) CO2 as a potential treatment for apnea of prematurity. Seminars in perinatology, 2001, Volume: 25, Issue:2 Topics: Administration, Inhalation; Apnea; Birth Weight; Carbon Dioxide; Gestational Age; Humans; Infant, Ne	2001
Inhalation of low (0.5%-1.5%) CO2 as a potential treatment for apnea of prematurity. Seminars in perinatology, 2001, Volume: 25, Issue:2 Topics: Administration, Inhalation; Apnea; Birth Weight; Carbon Dioxide; Gestational Age; Humans; Infant, Ne	2001
Inhalation of low (0.5%-1.5%) CO2 as a potential treatment for apnea of prematurity. Seminars in perinatology, 2001, Volume: 25, Issue:2 Topics: Administration, Inhalation; Apnea; Birth Weight; Carbon Dioxide; Gestational Age; Humans; Infant, Ne	2001
Home apnea monitor use in preterm infants discharged from newborn intensive care units. The Journal of pediatrics, 2001, Volume: 139, Issue:2 Topics: Apgar Score; Apnea; Birth Weight; Cross-Sectional Studies; Female; Gestational Age; Humans; Infant,	2001
Inter-neonatal intensive care unit variation in discharge timing: influence of apnea and feeding management. Pediatrics, 2001, Volume: 108, Issue:4 Topics: Age Factors; Apnea; Birth Weight; Body Temperature Regulation; Bradycardia; Child Development; Feedi	2001
Effect of continuous positive airway pressure on breathing pattern of infants with respiratory-distress syndrome. Lancet (London, England), 1975, Feb-08, Volume: 1, Issue:7902 Topics: Apnea; Birth Weight; Blood Pressure; Bradycardia; Carbon Dioxide; Heart; Heart Rate; Humans; Infant;	1975
Use of nasal continuous positive airway pressure to treat severe recurrent apnoea in very preterm infants. Lancet (London, England), 1976, Sep-25, Volume: 2, Issue:7987 Topics: Apnea; Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Male; Monitoring, Physiologic	1976
Sleep state, apnea and bradycardia in pre-term infants. Developmental medicine and child neurology, 1977, Volume: 19, Issue:2 Topics: Apnea; Birth Weight; Bradycardia; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infan	1977
Prevention of apnea and bradycardia in low-birthweight infants. Pediatrics, 1975, Volume: 55, Issue:5 Topics: Apnea; Birth Weight; Bradycardia; Carbon Dioxide; Female; Humans; Hydrogen-Ion Concentration; Infant	1975
The influence of apnea and physical activity on arterial blood pressure and transcutaneous oxygen tension in the newborn. Birth defects original article series, 1979, Volume: 15, Issue:4 Topics: Apnea; Birth Weight; Blood Gas Analysis; Blood Pressure; Body Temperature; Crying; Eating; Heart Rat	1979
Three-year-old twins and singletons: a comparison of some perinatal, environmental, experiential, and developmental characteristics. Australian paediatric journal, 1979, Volume: 15, Issue:4 Topics: Apnea; Birth Weight; Child Development; Child, Preschool; Environment; Female; Gestational Age; Huma	1979
[Theophylline for prevention of apnea in premature infants (author's transl)]. Monatsschrift fur Kinderheilkunde, 1978, Volume: 126, Issue:8 Topics: Apnea; Birth Weight; Humans; Infant, Newborn; Infant, Premature, Diseases; Tachycardia; Theophylline	1978
Mechanical ventilation of infants of less than 1,501 gm birth weight: Health, growth, and neurologic sequelae. The Journal of pediatrics, 1976, Volume: 88, Issue:4 Pt 1 Topics: Apnea; Birth Weight; Body Height; Child, Preschool; Female; Follow-Up Studies; Growth; Hemiplegia; H	1976
Effect of exchange transfusion on elimination of theophylline in premature neonates. The Journal of pediatrics, 1977, Volume: 91, Issue:2 Topics: Aminophylline; Apnea; Birth Weight; Dose-Response Relationship, Drug; Exchange Transfusion, Whole Bl	1977
[Apnea in infants with low birth weights]. Ugeskrift for laeger, 1976, Jun-28, Volume: 138, Issue:27 Topics: Apnea; Asphyxia Neonatorum; Birth Weight; Denmark; Humans; Infant, Newborn; Infant, Premature, Disea	1976
[Apnea cases in children born with low birth weights]. Ugeskrift for laeger, 1976, Jun-28, Volume: 138, Issue:27 Topics: Apnea; Asphyxia Neonatorum; Birth Weight; Humans; Infant, Newborn; Infant, Premature, Diseases; Resp	1976
[Prognostic score of newborn infants with low birth weight]. Ceskoslovenska pediatrie, 1976, Volume: 31, Issue:6 Topics: Apnea; Birth Weight; Body Temperature; Computers; Female; Humans; Infant, Newborn; Infant, Premature	1976
[Longtime artificial respiration of newborn infants using the Bird respirator]. Kinderarztliche Praxis, 1976, Volume: 44, Issue:2 Topics: Apnea; Asphyxia Neonatorum; Birth Weight; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases	1976
Surgical closure of patent ductus arteriosus in the premature infant with respiratory distress. Journal of pediatric surgery, 1975, Volume: 10, Issue:3 Topics: Aortography; Apnea; Birth Weight; Blood Pressure; Ductus Arteriosus, Patent; Electrocardiography; Fe	1975
Respiratory insufficiency syndrome (RIS) in preterm infants with gestational age of 32 weeks and less. Neonatal management and follow-up study. Acta paediatrica Scandinavica, 1975, Volume: 64, Issue:6 Topics: Apnea; Birth Weight; Female; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Intermitte	1975
Early neonatal hypocalcaemia. Archives of disease in childhood, 1975, Volume: 50, Issue:8 Topics: Apnea; Asphyxia Neonatorum; Birth Weight; Calcium; Ductus Arteriosus, Patent; Erythroblastosis, Feta	1975
[Infants of low birth weight after deliveries, morbidity and mortality (author's transl)]. Zeitschrift fur Geburtshilfe und Perinatologie, 1975, Volume: 179, Issue:4 Topics: Apgar Score; Apnea; Asphyxia Neonatorum; Birth Weight; Body Height; Breech Presentation; Cerebral He	1975
Neonatal complications and risk of intraventricular-periventricular hemorrhage. Clinical and experimental obstetrics & gynecology, 1992, Volume: 19, Issue:4 Topics: Acid-Base Equilibrium; Apnea; Birth Weight; Cerebral Hemorrhage; Female; Gestational Age; Humans; In	1992
Methods of resuscitation in low-Apgar-score newborn infants--a national survey. Acta paediatrica (Oslo, Norway : 1992), 1992, Volume: 81, Issue:10 Topics: Apgar Score; Apnea; Birth Certificates; Birth Weight; Clinical Protocols; Congenital Abnormalities;	1992
Apparent life-threatening events during infancy: a follow-up study of subsequent growth and development. Journal of developmental and behavioral pediatrics : JDBP, 1991, Volume: 12, Issue:3 Topics: Apgar Score; Apnea; Birth Weight; Child Development; Child, Preschool; Female; Follow-Up Studies; Ge	1991
Respiratory outcome in extremely premature infants following ketamine anaesthesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:3 Topics: Age Factors; Aminophylline; Anesthesia, Intravenous; Apnea; Birth Weight; Gestational Age; Humans; I	1991
Apnea, transient episodes of bradycardia, and periodic breathing in preterm infants. American journal of diseases of children (1960), 1990, Volume: 144, Issue:1 Topics: Apgar Score; Apnea; Birth Weight; Bradycardia; Cheyne-Stokes Respiration; Gestational Age; Heart Rat	1990
Prospective pneumogram recordings in preterm infants with and without clinical apnea and bradycardia. Pediatric pulmonology, 1990, Volume: 8, Issue:1 Topics: Apnea; Birth Weight; Bradycardia; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn	1990
Mechanical ventilation in newborn infants. African journal of medicine and medical sciences, 1988, Volume: 17, Issue:2 Topics: Apnea; Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Intermittent Positive-Pressur	1988
Risk factors for retrolental fibroplasia: experience with 3,025 premature infants. National Collaborative Study on Patent Ductus Arteriosus in Premature Infants. Pediatrics, 1985, Volume: 76, Issue:3 Topics: Anemia; Apnea; Birth Weight; Bronchopulmonary Dysplasia; Female; Histamine H1 Antagonists; Humans; I	1985
Physiologic effects of doxapram in idiopathic apnea of prematurity. The Journal of pediatrics, 1986, Volume: 108, Issue:1 Topics: Aminophylline; Apnea; Birth Weight; Blood Pressure; Carbon Dioxide; Doxapram; Gestational Age; Human	1986
Magnesium therapy in premature neonates with apnea neonatorum. Journal of the American College of Nutrition, 1988, Volume: 7, Issue:1 Topics: Apnea; Birth Weight; Bradycardia; Drug Administration Schedule; Follow-Up Studies; Gestational Age;	1988
Prognostic determinants in neonatal tetanus. East African medical journal, 1987, Volume: 64, Issue:1 Topics: Age Factors; Apnea; Birth Weight; Female; Humans; Infant, Newborn; Male; Prognosis; Prospective Stud	1987
The electrocardiogram in preterm infants with intraventricular hemorrhage and apnea. Journal of clinical monitoring, 1986, Volume: 2, Issue:1 Topics: Apnea; Birth Weight; Bradycardia; Cerebral Hemorrhage; Cerebral Ventricles; Echoencephalography; Ele	1986
Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study. Pediatrics, 1986, Volume: 78, Issue:1 Topics: Apnea; Birth Weight; Caffeine; Female; Humans; Infant, Newborn; Maternal Age; Pregnancy; Prenatal Ex	1986
Risk of hypoventilation in premature infants in car seats. The Journal of pediatrics, 1986, Volume: 109, Issue:2 Topics: Apnea; Automobiles; Birth Weight; Female; Heart Rate; Humans; Hypoventilation; Hypoxia; Infant; Infa	1986
Role of theophylline in pathogenesis of necrotizing enterocolitis. The Journal of pediatrics, 1986, Volume: 109, Issue:2 Topics: Apgar Score; Apnea; Birth Weight; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous; Gestat	1986
Epidemiological comparisons of sudden infant death syndrome with infant apnoea. Australian paediatric journal, 1986, Volume: 22 Suppl 1 Topics: Adult; Apnea; Birth Order; Birth Weight; Child, Preschool; Female; Humans; Infant; Infant, Newborn;	1986
Morbidity and mortality associated with exchange transfusion. Pediatrics, 1985, Volume: 75, Issue:2 Pt 2 Topics: Apnea; Birth Weight; Bradycardia; Calcium Gluconate; Exchange Transfusion, Whole Blood; Female; Hema	1985
Immediate effects of feeding on blood-gases and some cardiorespiratory functions in ill newborn infants. Lancet (London, England), 1974, Jun-01, Volume: 1, Issue:7866 Topics: Animals; Apnea; Birth Weight; Blood Pressure Determination; Blood Proteins; Carbon Dioxide; Enteral	1974
Diffusion anoxia at birth. Lancet (London, England), 1968, Oct-05, Volume: 2, Issue:7571 Topics: Adult; Anesthesia, Obstetrical; Apnea; Birth Weight; Cesarean Section; Diffusion; Female; Humans; Hy	1968
Delayed resorption of pulmonary alveolar fluid in the neonate. Radiology, 1972, Volume: 103, Issue:3 Topics: Apnea; Birth Weight; Cardiomegaly; Cesarean Section; Female; Hematocrit; Humans; Hypoproteinemia; In	1972
Periodic breathing in premature and neonatal babies: incidence, breathing pattern, respiratory gas tensions, response to changes in the composition of ambient air. Pediatric research, 1973, Volume: 7, Issue:4 Topics: Age Factors; Air; Apnea; Birth Weight; Body Weight; Carbon Dioxide; Electrocardiography; Humans; Inf	1973
Improved prognosis for infants of very low birthweight. Pediatrics, 1974, Volume: 54, Issue:6 Topics: Anti-Bacterial Agents; Apnea; Bacterial Infections; Birth Weight; Body Temperature Regulation; Child	1974
Very low birthweight and later intelligence. Developmental medicine and child neurology, 1974, Volume: 16, Issue:6 Topics: Apnea; Birth Weight; Black People; Female; Fertility; Fetal Diseases; Gestational Age; Humans; Hyper	1974
[Electric current as stimulus in immature babies with recurrent apneic attacks? (author's transl)]. Padiatrie und Padologie, 1974, Volume: 9, Issue:1 Topics: Anti-Bacterial Agents; Apnea; Birth Weight; Burns, Electric; Electric Stimulation; Electricity; Gest	1974
Neonatal at risk factors. The New Zealand medical journal, 1972, Volume: 75, Issue:480 Topics: Apgar Score; Apnea; Birth Weight; Child Development; Child, Preschool; Follow-Up Studies; Gestationa	1972
Morbidity and mortality of infants weighing less than 1,000 grams in an intensive care nursery. Pediatrics, 1972, Volume: 50, Issue:1 Topics: Apgar Score; Apnea; Bacterial Infections; Birth Weight; Body Temperature Regulation; Central Nervous	1972
Positive airway pressure in respiratory distress syndrome. The Medical journal of Australia, 1974, Jan-26, Volume: 1, Issue:4 Topics: Apnea; Autopsy; Birth Weight; Carbon Dioxide; Cerebral Hemorrhage; Cerebral Ventricles; Humans; Infa	1974
The relationship of apnoea and stridor in spina bifida to other unexplained infant deaths. Developmental medicine and child neurology, 1974, Volume: 16, Issue:6 Suppl 32 Topics: Age Factors; Apnea; Birth Weight; Bradycardia; Carbon Dioxide; Cyanosis; Humans; Hydrocephalus; Infa	1974
The association of hypocalcemia and recurrent apnea in premature infants. American journal of obstetrics and gynecology, 1972, Jul-01, Volume: 113, Issue:5 Topics: Abruptio Placentae; Apgar Score; Apnea; Birth Weight; Blood Proteins; Calcium; Female; Gestational A	1972
THAM v. sodium bicarbonate in idiopathic respiratory distress syndrome. Archives of disease in childhood, 1973, Volume: 48, Issue:4 Topics: Apnea; Autopsy; Bicarbonates; Birth Weight; Carbon Dioxide; Cerebral Hemorrhage; Female; Gestational	1973
The improving outlook for the small prematurely born infant. Developmental medicine and child neurology, 1973, Volume: 15, Issue:4 Topics: Apnea; Asphyxia Neonatorum; Attention Deficit Disorder with Hyperactivity; Birth Weight; Child; Chil	1973
Transient cataracts in low-birth-weight infants. The Journal of pediatrics, 1973, Volume: 82, Issue:2 Topics: Acidosis; Ampicillin; Apgar Score; Apnea; Bicarbonates; Birth Weight; Blood Pressure; Body Temperatu	1973
Spinal cord damage in a newborn infant. Archives of disease in childhood, 1974, Volume: 49, Issue:1 Topics: Apnea; Atrophy; Birth Injuries; Birth Weight; Cephalometry; Cyanosis; Female; Fetal Heart; Heart Rat	1974
Ventilator therapy in the newborn. Some mechanical considerations. Archives of disease in childhood, 1970, Volume: 45, Issue:242 Topics: Apnea; Birth Weight; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Methods;	1970
Periodic breathing and apnea in preterm infants. I. Evidence for hypoventilation possibly due to central respiratory depression. Pediatrics, 1972, Volume: 50, Issue:2 Topics: Apnea; Birth Weight; Carbon Dioxide; Chemoreceptor Cells; Cheyne-Stokes Respiration; Female; Gestati	1972
Periodic breathing and apnea in preterm infants. II. Hypoxia as a primary event. Pediatrics, 1972, Volume: 50, Issue:2 Topics: Apnea; Birth Weight; Carbon Dioxide; Cheyne-Stokes Respiration; Female; Gestational Age; Heart Rate;	1972
Epidemic listeriosis in the newborn. British medical journal, 1971, Sep-25, Volume: 3, Issue:5777 Topics: Apnea; Birth Weight; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Listeriosis; Lung;	1971
Artificial ventilation in respiratory failure in the newborn. The Medical journal of Australia, 1971, Sep-25, Volume: 2, Issue:13 Topics: Age Factors; Apnea; Australia; Birth Weight; Gestational Age; Humans; Infant, Newborn; Infant, Newbo	1971
The pre-term baby. British medical journal, 1971, Nov-13, Volume: 4, Issue:5784 Topics: Anemia; Apnea; Birth Weight; Cerebral Hemorrhage; Enterocolitis, Pseudomembranous; Gestational Age;	1971
[Experiences in apparative respiration control in premature and mature newborn infants]. Monatsschrift fur Kinderheilkunde, 1971, Volume: 119, Issue:7 Topics: Apgar Score; Apnea; Bilirubin; Birth Weight; Gestational Age; Humans; Infant, Newborn; Infant, Prema	1971
[Indications for exchange transfusions in premature infants]. Bibliotheca haematologica, 1969, Volume: 32 Topics: Acidosis, Respiratory; Apnea; Birth Weight; Exchange Transfusion, Whole Blood; Female; Humans; Hyper	1969
Apnea in premature infants and incubator-air-temperature changes. The New England journal of medicine, 1970, Feb-26, Volume: 282, Issue:9 Topics: Air; Apnea; Birth Weight; Body Temperature; Body Temperature Regulation; Environmental Exposure; Fem	1970
Indications for mechanical ventilation in infants with hyaline membrane disease. Pediatrics, 1970, Volume: 46, Issue:2 Topics: Apnea; Autopsy; Birth Weight; Blood; Carbon Dioxide; Female; Follow-Up Studies; Gestational Age; Hea	1970
Clinical indications for mechanical ventilation in newborn infants. Biology of the neonate, 1970, Volume: 16, Issue:1 Topics: Apnea; Asphyxia Neonatorum; Birth Weight; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant,	1970
Results of artificial ventilation. Experience at the Hospital for Sick Children, Toronto. Biology of the neonate, 1970, Volume: 16, Issue:1 Topics: Age Factors; Apnea; Birth Weight; Body Temperature; Female; Humans; Infant Mortality; Infant, Newbor	1970
Low birth weight and intensive care. British medical journal, 1970, Sep-19, Volume: 3, Issue:5724 Topics: Apnea; Birth Weight; Female; Fetal Death; Gestational Age; Humans; Infant Mortality; Infant, Newborn	1970
Association of hypoglycaemia with symptoms in the newborn. Archives of disease in childhood, 1968, Volume: 43, Issue:232 Topics: Adolescent; Adult; Apnea; Birth Weight; Factor Analysis, Statistical; Female; Hemorrhage; Humans; Hy	1968
[Primary resuscitation of newborn]. Praxis, 1968, Mar-05, Volume: 57, Issue:9 Topics: Acidosis; Alkalies; Alkalosis; Apnea; Birth Weight; Electroencephalography; Humans; Infant, Newborn;	1968
Apnea in premature infants: monitoring, incidence, heart rate changes, and an effect of environmental temperature. Pediatrics, 1969, Volume: 43, Issue:4 Topics: Apnea; Birth Weight; Bradycardia; Carbon Dioxide; Cyanosis; Heart Rate; Humans; Infant, Newborn; Inf	1969
Evidence of non-genetic origin of coarctation of the aorta. Canadian Medical Association journal, 1969, Jun-28, Volume: 100, Issue:24 Topics: Aortic Coarctation; Apnea; Birth Weight; Body Height; Child; Child, Preschool; Diseases in Twins; Fe	1969
Prematurity: observations upon its current significance and management. The Medical journal of Australia, 1969, Jun-07, Volume: 1, Issue:23 Topics: Apnea; Attitude to Health; Australia; Birth Weight; Communication; Cyanosis; Female; Fetal Death; Gl	1969
Perinatal and environmental factors in late neurogenic sequelae. I. Infants having birth weights under 1,500 grams. American journal of diseases of children (1960), 1966, Volume: 112, Issue:4 Topics: Apnea; Birth Weight; Child; Child, Preschool; Environment; Female; Follow-Up Studies; Humans; Infant	1966

apnea and Birth Weight