apnea and Anemia studies

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

Excerpt	Relevance	Reference
"Controversy exists as to the risk for postoperative apnea in former preterm infants."	9.08	Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. ( Coté, CJ; Downes, JJ; Kurth, CD; Malviya, SV; Warner, LO; Welborn, LG; Zaslavsky, A, 1995)
" Second, we recommend the use of intravenous caffeine base 10 mg/kg in all infants at risk for postoperative apnea following general anesthesia."	8.79	Anesthesia and apnea. Perioperative considerations in the former preterm infant. ( Greenspun, JC; Welborn, LG, 1994)
" Central apneas were detected using continuous computer processing of chest impedance, electrocardiographic, and oximetry signals."	7.78	Anemia, apnea of prematurity, and blood transfusions. ( Clark, MT; Delos, JB; Kattwinkel, J; Lake, DE; Lee, H; Moorman, JR; Moorman, ME; Paget-Brown, A; Rusin, CG; Vergales, B; Zagol, K, 2012)
"We found recently that blood transfusions had no effect on bradycardia and hypoxemia, the clinically important components of apnea of prematurity, in mildly anemic infants."	7.71	Blood transfusion in anemic infants with apnea of prematurity. ( Adrian, S; Bohnhorst, B; Groneck, P; Poets, CF; Soditt, V; Westkamp, E, 2002)
"To examine the association between anemia and postoperative apnea in former preterm infants, 24 former preterm infants of less than 60 weeks postconceptual age undergoing inguinal hernia repair were studied."	7.68	Anemia and postoperative apnea in former preterm infants. ( Fink, R; Hannallah, RS; Luban, NL; Ruttimann, UE; Welborn, LG, 1991)
" Infants in the restrictive-transfusion group were more likely to have intraparenchymal brain hemorrhage or periventricular leukomalacia, and they had more frequent episodes of apnea, including both mild and severe episodes."	5.11	Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. ( Bell, EF; Cress, GA; Johnson, KJ; Kromer, IJ; Mahoney, LT; Mock, DM; Seward, VJ; Strauss, RG; Widness, JA; Zimmerman, MB, 2005)
"Controversy exists as to the risk for postoperative apnea in former preterm infants."	5.08	Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. ( Coté, CJ; Downes, JJ; Kurth, CD; Malviya, SV; Warner, LO; Welborn, LG; Zaslavsky, A, 1995)
" Second, we recommend the use of intravenous caffeine base 10 mg/kg in all infants at risk for postoperative apnea following general anesthesia."	4.79	Anesthesia and apnea. Perioperative considerations in the former preterm infant. ( Greenspun, JC; Welborn, LG, 1994)
"Premature infants often have serious problems, such as anemia, retinopathy, hearing loss and apnea, before and after discharge from the neonatal intensive care unit."	4.78	The neonatal ICU graduate: Part I. Common problems. ( Hulseman, ML; Norman, LA, 1992)
" For purposes of the study, an apparent life-threatening event was defined as an episode of apnea, skin color change, or change in muscle tone."	3.72	Apparent life-threatening events in infants: high risk in the out-of-hospital environment. ( Clements, H; Henderson, D; Lewis, RJ; McCollough, M; Stratton, SJ; Taves, A, 2004)
"We found recently that blood transfusions had no effect on bradycardia and hypoxemia, the clinically important components of apnea of prematurity, in mildly anemic infants."	3.71	Blood transfusion in anemic infants with apnea of prematurity. ( Adrian, S; Bohnhorst, B; Groneck, P; Poets, CF; Soditt, V; Westkamp, E, 2002)
" On univariate analysis, gestation < or = 32 weeks, anemia, Blood transfusions, apnea and exposure to oxygen significantly increased the risk of developing ROP."	3.69	Retinopathy of prematurity: incidence and risk factors. ( Battu, RR; Rekha, S, 1996)
" Posttransfusion pneumocardiograms revealed significant reduction of periodic breathing, of apnea episodes with 11-15 second duration, of apnea density, and of heart rate."	3.68	Transfusion-induced changes in the breathing pattern of healthy preterm anemic infants. ( Heimler, R; Sasidharan, P, 1992)
" Six-second apnea density was less than 1% in one group and greater than or equal to 5% in the other."	3.68	Relationship between determinants of oxygen delivery and respiratory abnormalities in preterm infants with anemia. ( Bifano, EM; Borer, J; Smith, F, 1992)
"To examine the association between anemia and postoperative apnea in former preterm infants, 24 former preterm infants of less than 60 weeks postconceptual age undergoing inguinal hernia repair were studied."	3.68	Anemia and postoperative apnea in former preterm infants. ( Fink, R; Hannallah, RS; Luban, NL; Ruttimann, UE; Welborn, LG, 1991)
" In the past, indications for transfusion have included tachypnea, tachycardia, poor weight gain, apnea, bradycardia, pallor, lethargy, decreased activity, or poor feeding."	3.67	Assessing the need for transfusion of premature infants and role of hematocrit, clinical signs, and erythropoietin level. ( Donohue, PK; Jones, MD; Keyes, WG; Oski, FA; Spivak, JL, 1989)
" every 2 min, until the appearance of apnea."	3.66	Effects of anemia and growth retardation on respiratory activity in the piglet. ( Downing, SE; Lee, JC, 1979)
" An increase of DLCO for 20% of predicted normal at decreasing apnea time (tA = 5 sec) resulted from an increased pulmonary capillary blood volume for 50--90% of the predicted value (at tA = 10 sec), whereas membrane diffusing capacity remained unchanged over the range of apnea times."	3.66	Effects of abnormal hemoglobin concentration in human blood on membrane diffusing capacity of the lung and on pulmonary capillary blood volume. ( Riepl, G, 1978)
"If caffeine was found to have a greater effect, this would influence prescribing habits."	2.69	Comparison of the effects of theophylline and caffeine on serum erythropoietin concentration in premature infants. ( Fang, S; Gamsu, HR; Greenough, A; Marsden, JT; Peters, TJ; Sherwood, RA, 1998)
"Retinopathy of prematurity was detected in 10."	1.35	Risk factors for retinopathy of prematurity in six neonatal intensive care units in Beijing, China. ( Chen, Y; Gilbert, C; Jiang, YR; Li, XX; Liang, JH; Yin, H; Zhao, MW, 2008)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (28.13)	18.7374
1990's	14 (43.75)	18.2507
2000's	5 (15.63)	29.6817
2010's	4 (12.50)	24.3611
2020's	0 (0.00)	2.80

Trial			Phase	Enrollment	Study Type	Start Date	Status
Randomized Trial of Liberal Versus Restrictive Guidelines for Red Blood Cell Transfusion in Preterm Infants[NCT00369005]				100 participants	Interventional	1992-12-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Oxygen stores. International anesthesiology clinics, 1981,Fall, Volume: 19, Issue:3 Topics: Anemia; Anesthesia; Apnea; Hemodilution; Humans; Hypoxia; Infant; Infant, Newborn; Infant, Newborn,	1981
Anesthesia and apnea. Perioperative considerations in the former preterm infant. Pediatric clinics of North America, 1994, Volume: 41, Issue:1 Topics: Age Factors; Anemia; Anesthesia; Apnea; Bradycardia; Caffeine; Clinical Protocols; Gestational Age;	1994
The neonatal ICU graduate: Part I. Common problems. American family physician, 1992, Volume: 45, Issue:3 Topics: Anemia; Apnea; Bronchopulmonary Dysplasia; Hearing Disorders; Humans; Infant; Infant, Low Birth Weig	1992

Article	Year
Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. Pediatrics, 2005, Volume: 115, Issue:6 Topics: Anemia; Apnea; Blood Donors; Brain Damage, Chronic; Bronchopulmonary Dysplasia; Cerebral Hemorrhage;	2005
Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. Anesthesiology, 1995, Volume: 82, Issue:4 Topics: Aging; Analysis of Variance; Anemia; Anesthesia; Apnea; Birth Weight; Hernia, Inguinal; Humans; Infa	1995
Effect of blood transfusion on apnoea, bradycardia and hypoxaemia in preterm infants. European journal of pediatrics, 1997, Volume: 156, Issue:4 Topics: Anemia; Apnea; Blood Transfusion; Bradycardia; Female; Hemodynamics; Humans; Hypoxia; Infant, Newbor	1997
Comparison of the effects of theophylline and caffeine on serum erythropoietin concentration in premature infants. European journal of pediatrics, 1998, Volume: 157, Issue:5 Topics: Anemia; Apnea; Caffeine; Erythropoietin; Humans; Infant, Newborn; Infant, Premature; Infant, Prematu	1998

Article	Year
Breath-holding spells in infants. Canadian family physician Medecin de famille canadien, 2015, Volume: 61, Issue:2 Topics: Anemia; Apnea; Cyanosis; Electrocardiography; Female; Humans; Infant; Male; Stress, Psychological; U	2015
Anemia, apnea of prematurity, and blood transfusions. The Journal of pediatrics, 2012, Volume: 161, Issue:3 Topics: Algorithms; Anemia; Apnea; Blood Transfusion; Cardiography, Impedance; Comorbidity; Electrocardiogra	2012
Reply to Nakashima et al. The Journal of pediatrics, 2013, Volume: 162, Issue:4 Topics: Anemia; Apnea; Blood Transfusion; Humans; Infant, Very Low Birth Weight	2013
Oxygen delivery and apnea. The Journal of pediatrics, 2013, Volume: 162, Issue:4 Topics: Anemia; Apnea; Blood Transfusion; Humans; Infant, Very Low Birth Weight	2013
Blood transfusion in anemic infants with apnea of prematurity. Biology of the neonate, 2002, Volume: 82, Issue:4 Topics: Anemia; Apnea; Bradycardia; Erythrocyte Transfusion; Female; Gestational Age; Heart Rate; Humans; In	2002
Apparent life-threatening events in infants: high risk in the out-of-hospital environment. Annals of emergency medicine, 2004, Volume: 43, Issue:6 Topics: Anemia; Apnea; Cohort Studies; Cyanosis; Dehydration; Emergencies; Emergency Medical Services; Femal	2004
Apnea in an infant: what should I look for? Pediatric emergency care, 2007, Volume: 23, Issue:5 Topics: Anemia; Apnea; Battered Child Syndrome; Brain Injuries; Cardiopulmonary Resuscitation; Cerebrospinal	2007
Risk factors for retinopathy of prematurity in six neonatal intensive care units in Beijing, China. The British journal of ophthalmology, 2008, Volume: 92, Issue:3 Topics: Abruptio Placentae; Anemia; Apnea; Birth Weight; China; Female; Gestational Age; Humans; Hypoxia-Isc	2008
Acute proliferative retrolental fibroplasia: multivariate risk analysis. Transactions of the American Ophthalmological Society, 1983, Volume: 81 Topics: Analysis of Variance; Anemia; Apnea; Birth Weight; Bronchopulmonary Dysplasia; Cerebral Hemorrhage;	1983
Breath-holding spells: waiting to inhale, waiting for systole, or waiting for iron therapy? The Journal of pediatrics, 1997, Volume: 130, Issue:4 Topics: Anemia; Apnea; Heart Arrest; Heart Rate; Humans; Infant; Iron	1997
Breath-holding spells in a patient with transient erythroblastopenia of childhood. The Journal of pediatrics, 1997, Volume: 130, Issue:4 Topics: Anemia; Apnea; Erythroblasts; Erythrocyte Count; Humans; Infant; Iron; Male	1997
Retinopathy of prematurity: incidence and risk factors. Indian pediatrics, 1996, Volume: 33, Issue:12 Topics: Analysis of Variance; Anemia; Apnea; Blood Transfusion; Cohort Studies; Cryosurgery; Follow-Up Studi	1996
Management of breath holding spells. Indian pediatrics, 1999, Volume: 36, Issue:3 Topics: Anemia; Apnea; Child; Child, Preschool; Cyanosis; Humans; Hypoxia, Brain; Prognosis; Risk Assessment	1999
Effects of anemia and growth retardation on respiratory activity in the piglet. Biology of the neonate, 1979, Volume: 36, Issue:5-6 Topics: Age Factors; Anemia; Animals; Animals, Newborn; Apnea; Chloralose; Dose-Response Relationship, Drug;	1979
Effects of abnormal hemoglobin concentration in human blood on membrane diffusing capacity of the lung and on pulmonary capillary blood volume. Respiration; international review of thoracic diseases, 1978, Volume: 36, Issue:1 Topics: Anemia; Apnea; Capillaries; Carbon Monoxide; Hemoglobins; Humans; Male; Polycythemia; Pulmonary Circ	1978
Reduced haemoglobin levels in infants presenting with apparent life-threatening events--a retrospective investigation. Acta paediatrica (Oslo, Norway : 1992), 1992, Volume: 81, Issue:4 Topics: Age Factors; Anemia; Apnea; Bias; Erythrocyte Count; Female; Hemoglobins; Humans; Incidence; Infant;	1992
Transfusion-induced changes in the breathing pattern of healthy preterm anemic infants. Pediatric pulmonology, 1992, Volume: 12, Issue:3 Topics: Anemia; Apnea; Blood Transfusion; Hematocrit; Hemodynamics; Humans; Infant; Infant, Newborn; Infant,	1992
Relationship between determinants of oxygen delivery and respiratory abnormalities in preterm infants with anemia. The Journal of pediatrics, 1992, Volume: 120, Issue:2 Pt 1 Topics: Anemia; Apnea; Blood Transfusion; Cardiac Output; Hemoglobins; Humans; Infant, Newborn; Infant, Prem	1992
Anemia and postoperative apnea in former preterm infants. Anesthesiology, 1991, Volume: 74, Issue:6 Topics: Anemia; Apnea; Hernia, Inguinal; Humans; Infant; Infant, Newborn; Infant, Premature; Postoperative C	1991
Postoperative apnoea in former preterm infants: does anaemia increase the risk? Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2 Topics: Anemia; Apnea; Bradycardia; Hematocrit; Hernia, Inguinal; Humans; Infant, Newborn; Infant, Premature	1990
Assessing the need for transfusion of premature infants and role of hematocrit, clinical signs, and erythropoietin level. Pediatrics, 1989, Volume: 84, Issue:3 Topics: Anemia; Apnea; Blood Cell Count; Blood Transfusion; Bradycardia; Erythrocyte Transfusion; Erythropoi	1989
Risk factors for retrolental fibroplasia: experience with 3,025 premature infants. National Collaborative Study on Patent Ductus Arteriosus in Premature Infants. Pediatrics, 1985, Volume: 76, Issue:3 Topics: Anemia; Apnea; Birth Weight; Bronchopulmonary Dysplasia; Female; Histamine H1 Antagonists; Humans; I	1985
Office care of the premature infant. American family physician, 1986, Volume: 33, Issue:5 Topics: Anemia; Apnea; Blood Pressure; Bronchopulmonary Dysplasia; Growth; Hearing Tests; Heart Rate; Humans	1986
The pre-term baby. British medical journal, 1971, Nov-13, Volume: 4, Issue:5784 Topics: Anemia; Apnea; Birth Weight; Cerebral Hemorrhage; Enterocolitis, Pseudomembranous; Gestational Age;	1971
Cyanotic and pallid syncopal attacks in children (breath-holding spells). Developmental medicine and child neurology, 1969, Volume: 11, Issue:6 Topics: Adolescent; Age Factors; Anemia; Apnea; Child; Child Behavior; Child, Preschool; Crying; Emotions; F	1969

apnea and Anemia

Research Excerpts

Research

Studies (32)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Goldman, RD	1
Zagol, K	1
Lake, DE	1
Vergales, B	1
Moorman, ME	1
Paget-Brown, A	1
Lee, H	1
Rusin, CG	1
Delos, JB	1
Clark, MT	1
Moorman, JR	1
Kattwinkel, J	2
Kovatis, KZ	1
Nakashima, J	1
Ohashi, A	1
Kaneko, K	1
Westkamp, E	1
Soditt, V	1
Adrian, S	1
Bohnhorst, B	2
Groneck, P	1
Poets, CF	3
Stratton, SJ	1
Taves, A	1
Lewis, RJ	1
Clements, H	1
Henderson, D	1
McCollough, M	1
Bell, EF	1
Strauss, RG	1
Widness, JA	1
Mahoney, LT	1
Mock, DM	1
Seward, VJ	1
Cress, GA	1
Johnson, KJ	1
Kromer, IJ	1
Zimmerman, MB	1
Swischuk, LE	1
Chen, Y	1
Li, XX	1
Yin, H	1
Gilbert, C	1
Liang, JH	1
Jiang, YR	1
Zhao, MW	1
Flynn, JT	1
Stirt, JA	1
Sullivan, SF	1
Coté, CJ	1
Zaslavsky, A	1
Downes, JJ	1
Kurth, CD	1
Welborn, LG	4
Warner, LO	1
Malviya, SV	1
Greenspun, JC	1
Hannon, DW	1
Tam, DA	1
Rash, FC	1
Pauls, U	1
Rekha, S	1
Battu, RR	1
Fang, S	1
Sherwood, RA	1
Gamsu, HR	1
Marsden, JT	1
Peters, TJ	1
Greenough, A	1
Mittal, R	1
Lee, JC	1
Downing, SE	1
Riepl, G	1
Hulseman, ML	1
Norman, LA	1
Samuels, MP	1
Wardrop, CA	1
Picton-Jones, E	1
Southall, DP	1
Sasidharan, P	1
Heimler, R	1
Bifano, EM	1
Smith, F	1
Borer, J	1
Hannallah, RS	2
Luban, NL	1
Fink, R	2
Ruttimann, UE	1
Higgins, T	1
Luban, N	1
Keyes, WG	1
Donohue, PK	1
Spivak, JL	1
Jones, MD	1
Oski, FA	1
Purohit, DM	1
Ellison, RC	1
Zierler, S	1
Miettinen, OS	1
Nadas, AS	1
Trachtenbarg, DE	1
Miller, TC	1
Robinson, R	1
Laxdal, T	1
Gomez, MR	1
Reiher, J	1