apigenin and Burns

Cepan Cream has been applied in therapeutics for 20 years. This drug is used for topical treatment of burn scars and keloids as well as post-operative scars and contractures. Cepan produces a multidirectional effect. Cepan is well tolerated. Pharmacological property analysis of active ingredients, results of physical, biochemical studies and clinical estimation indicate that the evaluated preparation is both effective and safe. Lately, new information on Cepan effectiveness in eyelids inflammation caused by parasite Demodex folliculorum has been particulary interesting.

Topics: Allantoin; Animals; Blepharitis; Burns; Chamomile; Cicatrix; Drug Combinations; Drug Synergism; Eyelids; Female; Heparin; Humans; Keloid; Male; Matricaria; Middle Aged; Mite Infestations; Mites; Ointments; Onions; Phytotherapy; Plant Extracts; Species Specificity

Cepan Cream is used for the topical treatment of scars and keloids resulting from burns, post-operative scars, and contractures. Cepan Cream makes scars more elastic, softer and paler. Plant extracts, heparin and allantoin in Cepan act on the biochemical processes in the developing connective tissue, preventing the formation of hyperplastic scars. These active ingredients enhance swelling, softening and loosening of connective tissue. It exerts softening and smoothing action on indurated and hyperplastic scar tissue, improving collagen structure. It promotes tissue regeneration and reduces exuberant granulation. Cepan is well tolerated.

Topics: Administration, Topical; Adult; Allantoin; Burns; Chamomile; Child; Dermatologic Agents; Drug Combinations; Heparin; Humans; Ointments; Onions; Plant Extracts; Wound Healing

Regarding the importance of anxiety management and improvement of the quality of sleep in patients with burn injuries, this study aimed to determine the effect of aromatherapy massage (using aromatic oils of lavender and chamomile) on the anxiety and sleep quality of the patients with burn injuries.. In a quasi-experimental study, 105 patients with burns were recruited by convenience sampling method and then assigned into three groups (control, placebo massage, and combined aromatic oil massage). The study intervention was performed 20min before bedtime in three sessions, within a week. The control group was only under daily routine care. The study data were collected using the Persian version of Spielberg's anxiety scale and the Pittsburgh Sleep Quality Inventory. Descriptive and inferential statistical tests were used to analyze the data in SPSS version 20.. The results showed a significant difference among the three groups in terms of anxiety score (P<0.001) and in terms of sleep quality after the intervention (P=0.027).. Since the aromatherapy massage as a non-pharmacological and simple method can improve the anxiety and quality of sleep in patients with burns, it is suggested that nurses and burn medical care team apply it to reduce burn patients' anxiety and promote their sleep quality. Applying massage alone also reduces anxiety in burn survivors.

Topics: Adult; Anxiety; Aromatherapy; Burns; Chamomile; Female; Humans; Iran; Lavandula; Male; Massage; Middle Aged; Oils, Volatile; Plant Oils; Sleep; Sleep Latency

Topics: Adolescent; Adult; Allantoin; Burns; Chamomile; Child; Child, Preschool; Cicatrix; Dermatologic Agents; Drug Combinations; Elastic Tissue; Emollients; Heparin; Humans; Middle Aged; Ointments; Onions; Plant Extracts