amphotericin-b and Pyelonephritis
amphotericin-b has been researched along with Pyelonephritis* in 31 studies
Reviews
4 review(s) available for amphotericin-b and Pyelonephritis
Article | Year |
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[Management of fungal urinary tract infections].
Fungal urinary tract infections (funguria) are rare in community medicine, but common in hospitals where 10 to 30% of urine cultures isolate Candida species. Clinical features vary from asymptomatic urinary tract colonization (the most common situation) to cystitis, pyelonephritis, or even severe sepsis with fungemia. The pathologic nature of funguria is closely related to host factors, and management depends mainly on the patient's underlying health status. Microbiological diagnosis of funguria is usually based on a fungal concentration of more than 10(3)/mm(3) in urine. No cutoff point has been defined for leukocyte concentration in urine. Candida albicans is the most commonly isolated species, but previous antifungal treatment and previous hospitalization affect both species and susceptibility to antifungal agents. Treatment is recommended only when funguria is symptomatic or in cases of fungal colonization when host factors increase the risk of fungemia. The antifungal agents used for funguria are mainly fluconazole and amphotericin B deoxycholate, because other drugs have extremely low concentrations in urine. Primary and secondary preventions are essential. The reduction of risk factors requires removing urinary catheters, limiting antibiotic treatment, and optimizing diabetes mellitus treatment. Topics: Aged; Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Cross Infection; Cystitis; Deoxycholic Acid; Drug Combinations; Female; Fluconazole; Fungemia; Fungi; Health Status; Hospital Mortality; Humans; Male; Mycoses; Primary Prevention; Pyelonephritis; Risk Factors; Urinary Catheterization; Urinary Tract Infections; Urine | 2007 |
Isolated renal mucormycosis: case report and review.
The 15th reported case of isolated renal mucormycosis (infection of the kidney with fungus of the order Mucorales, in the absence of infection elsewhere in the body) is presented. The patient was a 36-year-old human immunodeficiency virus-infected man, actively using iv drugs, who suffered 6 wk of flank pain and fever before diagnosis was made by percutaneous renal biopsy. He received 4 months of amphotericin B treatment, then no therapy for 6 months before dying with no evidence of mucormycosis. Isolated renal mucormycosis should be suspected in those with an underlying immunocompromising illness or history of iv drug use who have persistent flank pain and fever, but sterile urine cultures. Computed tomographic scanning with contrast should then be performed; findings of severe inflammation or bacterial infection, despite an indolent clinical course with sterile or nondiagnostic urine and blood cultures, are suggestive of isolated renal mucormycosis, and renal biopsy under computed tomographic guidance should be performed, despite the potential risk of disseminated infection. Although our patient was treated with amphotericin B alone, nephrectomy with or without amphotericin B therapy appears to be more likely to cure infection and relieve pain and constitutional symptoms. Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Biopsy; Drug Therapy, Combination; Fatal Outcome; Humans; Kidney; Male; Mucormycosis; Nephrectomy; Pyelonephritis | 1995 |
Urinary tract candidosis.
Topics: Adult; Amphotericin B; Candidiasis; Child; Cystitis; Diagnosis, Differential; Humans; Infant, Newborn; Pyelonephritis; Therapeutic Irrigation; Urinary Catheterization | 1988 |
[Generalized candida mycoses].
Topics: Amphotericin B; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Burns; Candida albicans; Candidiasis; Catheterization; Central Nervous System Diseases; Diabetes Complications; Diagnosis, Differential; Fluorescent Antibody Technique; Fluorouracil; Hemagglutination Inhibition Tests; Humans; Hydrogen-Ion Concentration; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Lung Diseases, Fungal; Nystatin; Pneumonia, Pneumocystis; Pyelonephritis; Respiratory Hypersensitivity; Sepsis; Serologic Tests | 1974 |
Other Studies
27 other study(ies) available for amphotericin-b and Pyelonephritis
Article | Year |
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Renal Mucormycosis: A Rare Cause of Urinary Tract Infection Leading to End-stage Renal Disease (ESRD).
Mucormycosis is a rare fungal infection often seen in immunocompromised hosts. Isolated renal mucormycosis may however present in immunocompetent children as renal failure and has a uniformly poor prognosis if not detected and treated early into the course of illness. We present a 3-year-old boy with unrelenting pyelonephritis in whom serial urine cultures done were negative. A final diagnosis of isolated renal mucormycosis was made by magnetic resonance imaging and renal biopsy. Topics: Abdominal Pain; Amphotericin B; Antifungal Agents; Child, Preschool; Dialysis; Fever; Humans; Kidney; Kidney Failure, Chronic; Magnetic Resonance Imaging; Male; Mucorales; Mucormycosis; Pyelonephritis; Treatment Outcome; Triazoles; Urinary Tract Infections; Vomiting | 2019 |
Successful Conservative Management of Bilateral Renal Mucormycosis.
Topics: Amphotericin B; Antifungal Agents; Conservative Treatment; Diagnosis, Differential; Humans; Kidney; Kidney Function Tests; Male; Middle Aged; Mucorales; Mucormycosis; Pyelonephritis; Tomography, X-Ray Computed | 2018 |
Diagnosed only if considered: isolated renal mucormycosis.
Topics: Adult; Amphotericin B; Antifungal Agents; Humans; Kidney; Kidney Diseases; Male; Mucormycosis; Pyelonephritis; Tomography, X-Ray Computed | 2015 |
Successful treatment of bilateral Paecilomyces pyelonephritis in a German shepherd dog.
A six-year-old female entire German shepherd dog was investigated for polyuria, polydipsia and lethargy. Investigations revealed a mild azotaemia and abdominal ultrasound revealed marked bilateral dilation of the renal pelves with echogenic material and proximal left hydroureter. Urine cytological examination and aspirates from the right renal pelvis revealed mats of fungal hyphae consistent with fungal bezoar formation. Fungal cultures revealed a profuse growth of Paecilomyces variotii. Initial treatment with oral itraconazole was unsuccessful, leading to bilateral nephrotomies to remove the fungal material. Postoperatively the Paecilomyces infection persisted despite continued itraconazole therapy. Treatment was commenced with amphotericin B, leading to resolution of the dog's clinical signs. To the authors' knowledge this is the first report of canine Paecilomyces pyelonephritis, without disseminated systemic disease, which documents its successful treatment. Topics: Amphotericin B; Animals; Antifungal Agents; Dog Diseases; Dogs; Female; Itraconazole; Kidney; Mycoses; Paecilomyces; Pyelonephritis | 2012 |
High prevalence of upper urinary tract involvement detected by 111indium-oxine leukocyte scintigraphy in patients with candiduria.
The purpose of this investigation was to assess the prevalence of upper urinary tract involvement in patients with candiduria by means of (111)indium-oxine-labeled leukocyte scintigraphy. An observational cohort study of patients with confirmed candiduria was conducted in an acute-care teaching hospital in Spain from March 2006 through February 2009. An (111)In-labeled leukocyte scan was performed in order to assess the upper urinary tract involvement. A series of non-matched patients without candiduria nor bacteriuria undergoing scintigraphy to exclude infections in other sites than the urinary tract was also studied. Demographics, baseline illness, and clinical data were recorded. Candiduria was detected in 428 patients, and scintigraphy was performed in 35 of these patients. Twenty-nine patients without candiduria nor bacteriuria were also studied. Positive renal scintigraphy was documented in 24 (68%) patients with confirmed candiduria and in 3 (10%) patients without candiduria (p < 0.005). Renal uptake was not associated with a higher mortality nor with re-admissions. Subclinical pyelonephritis could be more frequent in patients with candiduria than it has been previously considered. Topics: Aged; Aged, 80 and over; Amphotericin B; Candida; Candidiasis; Cohort Studies; Female; Humans; Indium; Male; Middle Aged; Prevalence; Pyelonephritis; Radionuclide Imaging; Spain; Urinary Tract; Urinary Tract Infections | 2012 |
[Management of fungal pyelonephritis with percutaneous pyelostomy in infants].
To explore the management of fungal pyelonephritis in infants.. Data from 5 cases with fungal pyelonephritis, including the clinical situation, laboratory examination, feature of imaging, and treatment were analyzed.. All the 5 cases were preterm and low birth weight infants. In 3 cases the disease was unilateral, in 2 cases were bilateral, and acute renal failure occurred. Fungus balls presented on imaging. Urine culture was positive of Candida albicans. Treatment with percutaneous nephrostomy, irrigation and antifungal agent were associated with good prognosis. Only 1 case died. The surviving patients were followed up for 10 - 20 months and the results showed normal growth and development. B-mode ultrasound examination did not show any malformation of the urinary system.. Fungal pyelonephritis was commom in preterm infants. Candida albicans was the major pathogenic microorganism. Percutaneous nephrostomy and drainage were effective in patients with urinary obstruction in relief of obstruction, early diagnosis and control of infection. Topics: Acute Kidney Injury; Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Chymotrypsin; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Nephrostomy, Percutaneous; Pyelonephritis; Treatment Outcome; Ultrasonography, Doppler, Color; Ureteral Obstruction; Urine | 2012 |
Emphysematous pyelonephritis caused by Candida tropicalis.
Topics: Amphotericin B; Candidiasis; Emphysema; Female; Humans; Middle Aged; Pyelonephritis; Radiography; Renal Dialysis | 2010 |
Limitations of caspofungin in the treatment of obstructive pyonephrosis due to Candida glabrata infection.
Caspofungin is a new antifungal agent with high-level activity against a number of Candida species including those that are resistant to azoles. Its good safety profile and low nephrotoxicity makes it an attractive drug to treat fungal infections in patients with compromised renal function. However, little is known about the clinical efficacy in the treatment of complicated urinary tract infections due to Candida species such as pyonephrosis.. We report a case of obstructive pyonephrosis due to an azole (fluconazole and itraconazole) resistant Candida glabrata strain that failed to respond to intravenous treatment with caspofungin. A sustained clinical and microbiological response was only achieved after percutaneous drainage and instillation of amphotericin B deoxycholate into the renal pelvis in combination with intravenous liposomal amphotericin B.. This case demonstrates the limitation of intravenous antifungal agents such as caspofungin as the sole treatment of an obstructive upper urinary tract infection due to Candida species. In order to achieve long term sustained cure from an obstructive pyonephrosis, pus and fungal balls should be drained and an anti-fungal agent such as amphotericin B deoxycholate instilled locally. The pharmacokinetics and role of caspofungin in the treatment of complicated Candida urinary tract infection is reviewed. Topics: Aged; Amphotericin B; Antifungal Agents; Azoles; Candida glabrata; Caspofungin; Drug Resistance, Multiple, Fungal; Echinocandins; Female; Humans; Injections, Intravenous; Lipopeptides; Peptides, Cyclic; Pyelonephritis | 2006 |
[Vascular Aspergillus infection in two recipients of kidneys from the same donor].
We describe a clinical case of two patients who received a cadaveric renal graft from the same donor in a multi-organ extraction procedure. The donor was a 39-years-old woman who died of intracranial tumour. A benign ganglioma was shown in biopsy. The two recipients received the same immunosuppressive regimen. Induction comprised cyclosporin A, steroids and basiliximab while cyclosporin A and steroids were used in maintenance immunosuppression. The A patient was a 53-year-old woman with chronic renal failure due to chronic pyelonephritis. She had been undergoing periodic haemodialysis for five years. She was hospitalised for sciatic pain refractory to rest and analgesics 35 days after transplantation. Two days later, her graft function deteriorated. Ultrasonography ruled out a urinary tract obstruction. Cyclosporine levels was normal. It was interpreted as an acute rejection episode and was treated with boluses of methylprednisolone (500 mg for 3 days). At the same time, her right leg began to show paraesthesia, coldness and a decreased arterial pulse. A spinal magnetic nuclear resonance was performed. It showed an aneurysm of right common iliac artery (fig. 1). An arteriography confirmed the existence of a pseudoaneurysm and an arteriovenous fistula to inferior vena cava (fig. 2). The B recipient was a 56-year-old woman with chronic renal failure due to chronic pyelonephritis. She required haemodialysis for two years. In the 4th month after transplantation her graft function deteriorated. Graft biopsy did not show acute cellular rejection, so she was kept on immunosuppressive treatment. A second graft biopsy was taken and no changes with the previous one was observed. Renal function deteriorated and haemodialysis was required. During the 6th month she began to show paraesthesia, coldness and decreased arterial pulse in her right leg. Ultrasonography showed pyelocaliectasis with an adjacent solid-liquid mass, abdominal CT scan confirmed. Arteriography proved the presence of a pseudoaneurysm of the right common iliac artery (fig. 3). Transplantectomy and pseudoaneurysm resection was performed in the two cases. Culture analysis revealed fungi identified as Aspergillus in both pseudoaneurysms. Medical treatment was started immediately with liposomal amphotericin B. The clinical evolution of the two recipients were different. While recipient A died, B patient recovered, requiring haemodialysis. Topics: Adrenal Cortex Hormones; Adult; Amphotericin B; Aneurysm, False; Aneurysm, Infected; Antibodies, Monoclonal; Arteriovenous Fistula; Aspergillosis; Basiliximab; Cadaver; Combined Modality Therapy; Cyclosporine; Fatal Outcome; Female; Humans; Iliac Artery; Immunocompromised Host; Kidney Transplantation; Liposomes; Middle Aged; Nephrectomy; Postoperative Complications; Pyelonephritis; Recombinant Fusion Proteins; Tissue Donors; Transplants; Vena Cava, Inferior | 2004 |
Impact of the order of initiation of fluconazole and amphotericin B in sequential or combination therapy on killing of Candida albicans in vitro and in a rabbit model of endocarditis and pyelonephritis.
In vitro time-kill studies and a rabbit model of endocarditis and pyelonephritis were used to define the impact that the order of exposure of Candida albicans to fluconazole (FLC) and amphotericin B (AMB), as sequential and combination therapies, had on the susceptibility of C. albicans to AMB and on the outcome. The contribution of FLC-induced resistance to AMB for C. albicans also was assessed. In vitro, AMB monotherapy rapidly killed each of four C. albicans strains; FLC alone was fungistatic. Preincubation of these fungi with FLC for 18 h prior to exposure to AMB decreased their susceptibilities to AMB for 8 to >40 h. Induced resistance to AMB was transient, but the duration of resistance increased with the length of FLC preincubation. Yeast sequentially incubated with FLC followed by AMB plus FLC (FLC-->AMB+FLC) showed fungistatic growth kinetics similar to that of fungi that were exposed to FLC alone. This antagonistic effect persisted for at least 24 h. Simultaneous exposure of C. albicans to AMB and FLC [AMB+FLC(simult)] demonstrated activity similar to that with AMB alone for AMB concentrations of > or =1 microg/ml; antagonism was seen using an AMB concentration of 0.5 microg/ml. The in vitro findings accurately predicted outcomes in our rabbit infection model. In vivo, AMB monotherapy and treatment with AMB for 24 h followed by AMB plus FLC (AMB-->AMB+FLC) rapidly sterilized kidneys and cardiac vegetations. AMB+FLC(simult) and FLC-->AMB treatments were slower in clearing fungi from infected tissues. FLC monotherapy and FLC-->AMB+FLC were both fungistatic and were the least active regimens. No adverse interaction was observed between AMB and FLC for the AMB-->FLC regimen. However, FLC-->AMB treatment was slower than AMB alone in clearing fungi from tissues. Thus, our in vitro and in vivo studies both demonstrate that preexposure of C. albicans to FLC reduces fungal susceptibility to AMB. The length of FLC preexposure and whether AMB is subsequently used alone or in combination with FLC determine the duration of induced resistance to AMB. Topics: Amphotericin B; Animals; Antifungal Agents; Area Under Curve; Candida albicans; Endocarditis; Fluconazole; Heart; Kidney; Kidney Function Tests; Male; Microbial Sensitivity Tests; Pyelonephritis; Rabbits; Time Factors | 2001 |
Efficacies of high-dose fluconazole plus amphotericin B and high-dose fluconazole plus 5-fluorocytosine versus amphotericin B, fluconazole, and 5-fluorocytosine monotherapies in treatment of experimental endocarditis, endophthalmitis, and pyelonephritis d
We compared the efficacies of fluconazole (Flu), amphotericin B (AmB), and 5-fluorocytosine (5FC) monotherapies with the combination of Flu plus 5FC and Flu plus AmB in a rabbit model of Candida albicans endocarditis, endophthalmitis, and pyelonephritis. The dose of Flu used was that which resulted in an area under the concentration-time curve in rabbits equivalent to that seen in humans who receive Flu at 1,600 mg/day, the highest dose not associated with central nervous system toxicity in humans. Quantitative cultures of heart valve vegetations, the choroid-retina, vitreous humor, and kidney were conducted after 1, 5, 14, and 21 days of therapy. All untreated controls died within 6 days of infection; animals treated with 5FC monotherapy all died within 18 days. In contrast, 93% of animals in the other treatment groups appeared well and survived until they were sacrificed. At day 5, the relative decreases in CFU per gram in the vitreous humor were greater in groups that received Flu alone and in combination with 5FC or AmB than in groups receiving AmB or 5FC monotherapies (P < 0. 005) but were similar thereafter. In the choroid-retina, 5FC was the least-active drug. However, there were no differences in choroidal fungal densities between the other treatment groups. On days 5 and 14 of therapy, fungal densities in kidneys of AmB recipients were lower than those resulting from the other therapies (P < 0.001 and P < or = 0.038, respectively) and AmB-plus-Flu therapy was antagonistic; however, all therapies for fungal pyelonephritis were similar by treatment day 21. While fungal counts in cardiac valves of Flu recipients were similar to those of controls on day 5 of therapy and did not change from days 1 to 21, AmB therapy significantly decreased valvular CFUs versus Flu at days 5, 14, and 21 (P < 0.005 at each time point). 5FC plus Flu demonstrated enhanced killing in cardiac vegetations compared with Flu or 5FC as monotherapies (P < 0. 03). Similarly, the combination of AmB and Flu was more active than Flu in reducing the fungal density in cardiac vegetations (P < 0.03). However, as in the kidney, AmB plus Flu demonstrated antagonism versus AmB monotherapy in the treatment of C. albicans endocarditis (P < 0.05, P = 0.036, and P < 0.008 on days 5, 14, and 21, respectively). Topics: Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; Creatinine; Endocarditis; Endophthalmitis; Fluconazole; Flucytosine; Kidney; Male; Microbial Sensitivity Tests; Myocardium; Pyelonephritis; Rabbits; Survival Analysis; Time Factors; Vitreous Body | 1999 |
Neonatal renal candidiasis.
A case is presented of renal candidiasis complicated by obstructive uropathy in a 4 month old infant. Management was successful with surgical decompression combined with peri-operative amphotericin B, followed by 3 weeks of oral ketoconazole and subsequently 6 weeks of oral fluconazole. Fluconazole was substituted for ketoconazole owing to persistent candiduria, and achieved rapid urinary sterilization. Fluconazole is an effective and less toxic alternative to prolonged courses of amphotericin B in the treatment of neonatal renal candidiasis. Topics: Amphotericin B; Candidiasis; Diagnostic Imaging; Drug Therapy, Combination; Fluconazole; Humans; Infant; Ketoconazole; Male; Pyelonephritis; Ureteral Obstruction | 1994 |
[Unusual course of candidiasis of the central nervous system].
Six months after an attack of pyelonephritis, adnexitis and candida colpitis an 18-year-old girl developed some clouding of consciousness. On neurological examination she showed organic behavioural changes, discrete anisocoria and possible meningism. Computed tomography revealed hydrocephalus and signs of increased cerebrospinal fluid (CSF) pressure. CSF contained 2336/3 cells, while total protein was raised to 7.0 g/l and lactate concentration to 6.85 mmol/l. Glucose concentration in CSF was 51 mg/dl and 75 mg/dl in serum. As tuberculous meningitis was suspected, treatment was started with four tuberculostatic drugs, but there was no improvement. Five weeks later microscopic CSF examination showed fungal spores and nonbranching hyphae. The maximal candida haemagglutination titre in CSF was 1:2048. CSF culture grew Candida albicans. The further course was complicated by side effects to the antimycotic drugs (amphotericin B between 4.5 and 45 mg daily; flucytosine 1.7 g four times daily) and recurrent obstruction in the ventricular system requiring repeated neurosurgical interventions. However, full cure was achieved after seven months' hospital treatment. Topics: Adolescent; Amphotericin B; Antitubercular Agents; Brain Diseases; Candida albicans; Candidiasis; Candidiasis, Vulvovaginal; Cerebrospinal Fluid; Diagnosis, Differential; Female; Flucytosine; Humans; Hydrocephalus; Pelvic Inflammatory Disease; Pyelonephritis; Tomography, X-Ray Computed; Tuberculosis, Meningeal | 1994 |
Failure of therapy with fluconazole for candidal endophthalmitis.
The incidence of candidemia and its complications, such as endophthalmitis, has measurably increased in recent years. However, the optimal method of treatment of hematogenous candidal infection remains a controversial issue. Traditional therapy with amphotericin B is associated with well-known adverse reactions. Many clinicians therefore prefer to use fluconazole, which is administered orally and is relatively less toxic. We recently observed a patient with candidal sepsis in whom blinding endophthalmitis developed despite aggressive and lengthy therapy with fluconazole. This grave clinical outcome and the data derived from experimental models of ocular candidal infection suggest that empirical usage of fluconazole may not be warranted in cases of disseminated candidiasis potentially complicated by endophthalmitis. Topics: Adult; Amphotericin B; Candidiasis; Cross Infection; Endophthalmitis; Female; Fluconazole; Fungemia; Humans; Pyelonephritis | 1993 |
Candida pyelonephritis complicating traumatic C5 quadriplegia: diagnosis and management.
We present the first reported case of Candida pyelonephritis in a spinal cord injured patient. In addition to multiple courses of empiric antibiotics, the neurogenic bladder and alteration in cell-mediated immunity found in spinal cord injured patients may have increased this patient's susceptibility to fungal disease. A 50-year-old patient with C5 motor functional quadriplegia developed Candid albicans pyelonephritis while undergoing rehabilitation. The patient had several surgical procedures and multiple courses of antibiotic therapy during acute hospitalization. He continued to have a hectic fever curve, leukocytosis with increased band forms, lethargy, and progressive uremia during rehabilitation. Successful investigation of the patient's condition included assessment of serologic tests for Candida precipitin antigen; multiple blood and urine cultures; exclusion of other causes of hectic fever; abdominal computerized tomogram, which revealed a left kidney hypodensity with irregular margins; and a retrograde pyelogram, which demonstrated multiple renal pelvic-filling defects. Cystoscopically placed ureteral stents, which relieved the genitourinary obstruction, drained gross pus from which Candida albicans was cultured; the patient was treated with amphotericin B and showed clinical improvement. Pathogenesis, presentation, diagnosis, and treatment of Candida pyelonephritis are reviewed. Topics: Algorithms; Amphotericin B; Candidiasis; Humans; Male; Middle Aged; Pyelonephritis; Quadriplegia; Spinal Cord Injuries; Tomography, X-Ray Computed; Urography | 1991 |
Comparison of amphotericin B and N-D-ornithyl amphotericin B methyl ester in experimental cryptococcal meningitis and Candida albicans endocarditis with pyelonephritis.
Amphotericin B and N-D-ornithyl amphotericin B methyl ester were compared for therapeutic efficacies against experimentally induced cryptococcal meningitis and Candida albicans endocarditis with pyelonephritis in rabbits. Antifungal activity of the two polyenes in vitro was similar for the yeasts used in these experiments. N-D-ornithyl amphotericin B methyl ester gave a slightly higher concentration in serum than amphotericin B did, but both drugs had similar elimination curves, and penetration into the cerebrospinal fluid was poor for both. Despite these similarities between the two polyenes, amphotericin B was much more effective than N-D-ornithyl amphotericin B methyl ester in the treatment of cryptococcal meningitis in rabbits. For C. albicans endocarditis, both polyenes had similar cure rates, but in vitro measurement of fungicidal activity in serum did not predict treatment outcome. For C. albicans pyelonephritis, both polyenes showed efficacy; because higher doses of the less toxic methyl ester could be used, it sterilized the urinary tract more often than amphotericin B. These studies indicate that in vivo and in vitro experiments may be needed to predict the results of treatment with polyenes. Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Cryptococcosis; Endocarditis; Kinetics; Meningitis; Microbial Sensitivity Tests; Mycoses; Pyelonephritis; Rabbits; Yeasts | 1985 |
Treatment of experimental murine candidiasis with liposome-associated amphotericin B.
Mice were challenged intravenously with Candida albicans, and then treated either with nothing (controls), amphotericin B-desoxycholate (AMB), or amphotericin B associated with liposomes (AMB-lipo). AMB-lipo permitted larger doses of amphotericin B to be given, and also appeared to have no severe toxicity in the animal model. High doses of AMB-lipo were protective, but at equal doses, AMB-lipo was not as effective as commercial AMB. Topics: Amphotericin B; Animals; Candidiasis; Liposomes; Mice; Mice, Inbred BALB C; Pyelonephritis | 1984 |
[Sepsis with Torulopsis glabrata probably originating from a renal focus].
Topics: Aged; Amphotericin B; Candida; Candidiasis; Diabetes Complications; Female; Humans; Pyelonephritis | 1974 |
Recovery from disseminated candidiasis in a premature neonate.
Topics: Amphotericin B; Antifungal Agents; Arthritis, Infectious; Candidiasis; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Endophthalmitis; Flucytosine; Humans; Infant, Newborn; Infant, Premature, Diseases; Meningitis; Osteomyelitis; Pyelonephritis; Radiography; Recurrence; Sepsis | 1974 |
Resistance to polyene antibiotics and correlated sterol changes in two isolates of Candida tropicalis from a patient with an amphotericin B-resistant funguria.
Topics: Amphotericin B; Candida; Candida albicans; Candidiasis; Cell Membrane; Cell Membrane Permeability; Chromatography, Gas; Chromatography, Thin Layer; Drug Resistance, Microbial; Ergosterol; Humans; Lanosterol; Mutation; Nystatin; Pyelonephritis; Spectrophotometry, Ultraviolet; Sterols | 1974 |
Chronic mucocutaneous candidiasis: immunologic and antibiotic therapy.
Topics: Adult; Age Factors; Amphotericin B; Anti-Bacterial Agents; Candidiasis, Cutaneous; Child; Child, Preschool; Chronic Disease; Dermatomycoses; Female; Foot Dermatoses; Furunculosis; Hand Dermatoses; Herpes Zoster; Humans; Immunity, Cellular; Immunity, Maternally-Acquired; Immunotherapy; Infant; Male; Pneumonia; Pyelonephritis; Remission, Spontaneous; Skin Tests; Staphylococcal Infections | 1974 |
Renal candidiasis: diagnosis and management.
Topics: Adult; Amphotericin B; Candidiasis; Female; Flucytosine; Humans; Kidney; Kidney Calculi; Pyelonephritis; Urine | 1973 |
Cryptococcal opportunism.
Topics: Amphotericin B; Cross Infection; Cryptococcosis; Cryptococcus; Humans; Pyelonephritis | 1968 |
Cryptococcal pyelonephritis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amphotericin B; Arthritis, Rheumatoid; Aspirin; Cryptococcosis; Cryptococcus; Female; Hematuria; Humans; Kidney Papillary Necrosis; Male; Meningitis; Middle Aged; Proteinuria; Pyelonephritis; Pyuria; Urea; Urinary Tract Infections | 1968 |
Candida pyelonephritis and candiduria: the clinical significance of candida albicans in urine cultures.
Topics: Adult; Amphotericin B; Candida; Candidiasis; Candidiasis, Cutaneous; Candidiasis, Oral; Candidiasis, Vulvovaginal; Feces; Female; Humans; Infant; Male; New York City; Pyelonephritis; Sputum | 1968 |
RENAL HISTOPATHOLOGY ASSOCIATED WITH DIFFERENT DEGREES OF AMPHOTERICIN B TOXICITY IN THE DOG.
Topics: Amphotericin B; Blood Urea Nitrogen; Dogs; Gastrointestinal Diseases; Kidney; Kidney Glomerulus; Kidney Tubules; Nephrocalcinosis; Pathology; Pharmacology; Pyelonephritis; Research; Toxicology; Urea | 1965 |
AN UNUSUAL IMMUNOLOGICAL REACTION IN SYSTEMIC CANDIDIASIS IN MAN.
Topics: Allergy and Immunology; Amphotericin B; Anti-Bacterial Agents; Antigens; Candidiasis; Desensitization, Immunologic; Drug Therapy; Immunization; Pyelonephritis; Skin Tests; Toxicology | 1965 |