amlexanox has been researched along with Pain in 8 studies
amlexanox: SRA-A antagonist;structure given in first source
amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "041)] was the most effective in reducing the pain score followed by Amlexanox [MD, -2." | 5.41 | COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. ( Cheng, YO; Gopinath, D; Shetty, NY; Syeed, MS; Veettil, SK, 2023) |
| "Amlexanox oral adhesive tablets are effective and safe in reducing aphthous ulcer pain and lesion size, as well as erythema and exudation in this Chinese cohort." | 5.12 | An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial. ( Cai, Y; Chen, F; Chen, Q; Lin, M; Liu, J; Shi, J; Wang, Y; Wang, Z; Zeng, X; Zhang, Y; Zhou, H, 2006) |
| "Amlexanox has been developed as a 5 percent topical oral paste for the treatment of patients with recurrent aphthous stomatitis (RAS) in most European countries." | 2.74 | A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial. ( Chen, Q; Chen, R; Dong, Y; Gao, F; Jiang, L; Lin, M; Liu, J; Meng, W; Wang, Z; Xu, T; Zeng, X; Zhong, X; Zhou, H, 2009) |
| "In vivo, we applied a mouse melanoma skin cancer model to assess tumour growth and melanoma-associated pain in IKKε knockout mice as well as C57BL/6 mice after inoculation with IKKε-negative cells." | 1.43 | The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model. ( Geisslinger, G; King-Himmelreich, TS; Laarmann, K; Meissner, M; Möser, CV; Niederberger, E; Olbrich, K; Wolters, MC, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YO | 1 |
| Veettil, SK | 1 |
| Syeed, MS | 1 |
| Shetty, NY | 1 |
| Gopinath, D | 1 |
| Zhou, LF | 1 |
| Zeng, W | 1 |
| Sun, LC | 1 |
| Wang, Y | 2 |
| Jiang, F | 1 |
| Li, X | 1 |
| Zheng, Y | 1 |
| Wu, GM | 1 |
| Möser, CV | 1 |
| Meissner, M | 1 |
| Laarmann, K | 1 |
| Olbrich, K | 1 |
| King-Himmelreich, TS | 1 |
| Wolters, MC | 1 |
| Geisslinger, G | 1 |
| Niederberger, E | 1 |
| Meng, W | 1 |
| Dong, Y | 1 |
| Liu, J | 2 |
| Wang, Z | 2 |
| Zhong, X | 1 |
| Chen, R | 1 |
| Zhou, H | 2 |
| Lin, M | 2 |
| Jiang, L | 1 |
| Gao, F | 1 |
| Xu, T | 1 |
| Chen, Q | 2 |
| Zeng, X | 2 |
| Bailey, J | 1 |
| McCarthy, C | 1 |
| Smith, RF | 1 |
| Murray, B | 1 |
| Biagioni, PA | 1 |
| Lamey, PJ | 1 |
| Cai, Y | 1 |
| Chen, F | 1 |
| Shi, J | 1 |
| Zhang, Y | 1 |
| Greer, RO | 1 |
| Lindenmuth, JE | 1 |
| Juarez, T | 1 |
| Khandwala, A | 1 |
2 reviews available for amlexanox and Pain
| Article | Year |
|---|---|
COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS.
Topics: Aminopyridines; Humans; Network Meta-Analysis; Pain; Stomatitis, Aphthous | 2023 |
Clinical inquiry. What is the most effective way to treat recurrent canker sores?
Topics: Administration, Topical; Aminopyridines; Anti-Allergic Agents; Anti-Infective Agents, Local; Anti-In | 2011 |
4 trials available for amlexanox and Pain
| Article | Year |
|---|---|
A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial.
Topics: Adhesiveness; Administration, Oral; Aminopyridines; Anti-Allergic Agents; China; Double-Blind Method | 2009 |
The efficacy of amlexanox OraDisc on the prevention of recurrent minor aphthous ulceration.
Topics: Administration, Topical; Adult; Aminopyridines; Anti-Allergic Agents; Body Temperature; Double-Blind | 2006 |
An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial.
Topics: Adhesives; Adolescent; Adult; Aged; Aminopyridines; Anti-Allergic Agents; Cohort Studies; Double-Bli | 2006 |
A double-blind study of topically applied 5% amlexanox in the treatment of aphthous ulcers.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Aminopyridines; Anti-Inflamm | 1993 |
2 other studies available for amlexanox and Pain
| Article | Year |
|---|---|
IKKε aggravates inflammatory response via activation of NF-κB in rheumatoid arthritis.
Topics: Aminopyridines; Animals; Arthritis, Experimental; I-kappa B Kinase; Inflammation Mediators; Male; Mi | 2018 |
The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model.
Topics: Aminopyridines; Animals; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Humans; I-kapp | 2016 |