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amiodarone and Goiter

amiodarone has been researched along with Goiter in 25 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).

Research Excerpts

ExcerptRelevanceReference
"To delineate the incidence, clinical features, diagnosis, and treatment options for amiodarone induced hyperthyroidism (AIH), we reviewed the medical records of ten patients with AIH."8.79Amiodarone induced hyperthyroidism: a case series and brief review of literature. ( Harjai, KJ; Licata, AA, 1996)
" He was diagnosed with atrial fibrillation 2 years previously and started on amiodarone and warfarin."7.80Amiodarone-induced thyrotoxicosis: type 1 or type 2? ( Khan, A; Puttanna, A; Raskauskiene, D, 2014)
"Amiodarone, an iodine-rich cardiac drug, may induce thyrotoxicosis (AIT), which can occur in patients with preexisting thyroid abnormalities and in subjects with apparently normal thyroid glands."7.69Serum interleukin-6 in amiodarone-induced thyrotoxicosis. ( Aghini-Lombardi, F; Bartalena, L; Braverman, LE; Brogioni, S; Grasso, L; Martino, E, 1994)
"Amiodarone iodine induced thyrotoxicosis occurs frequently in patients residing in areas of mild iodine deficiency and in patients with preexisting goiter."7.67Treatment of amiodarone associated thyrotoxicosis by simultaneous administration of potassium perchlorate and methimazole. ( Aghini-Lombardi, F; Baschieri, L; Braverman, LE; Lenziardi, M; Mariotti, S; Martino, E; Pinchera, A, 1986)
"Iodine induced hyperthyroidism is frequently observed in patients affected by euthyroid iodine deficient goiter when suddenly exposed to excess iodine."6.41Iodine excess and hyperthyroidism. ( Roti, E; Uberti, ED, 2001)
"Iodine is an essential element for thyroid hormone synthesis."6.41Iodine-Induced hypothyroidism. ( Georgopoulos, N; Kyriazopoulou, V; Markou, K; Vagenakis, AG, 2001)
"Transient hypothyroidism was observed in only two patients (5%) with AIH, though was not observed in TMNG."5.35Radioiodine therapy in patients with amiodarone-induced thyrotoxicosis (AIT). ( Bartkowiak, Z; Czarnywojtek, A; Czepczynski, R; Florek, E; Ruchala, M; Sowinski, J; Szczepanek, E; Wasko, R; Zamyslowska, H; Zgorzalewicz-Stachowiak, M, 2009)
"Treatment with amiodarone was continued; however, therapy with L-thyroxin was initiated, followed by a complete regression of the goiter."5.28Goiter and hypothyroidism during re-treatment with amiodarone in a patient who previously experienced amiodarone-induced thyrotoxicosis. ( Ish-Shalom, S; Kaplan, J, 1991)
"Amiodarone is an anti-arrhythmic drug with a content of 39% Iodine."5.27Congenital hypothyroid goiter and amiodarone. ( De Schepper, J; De Wolf, D; Deneyer, M; Sacre-Smits, L; Smitz, J; Verhaaren, H, 1988)
" More recently, it has been suggested that rhTSH is useful for treatment of multinodular goiter and amiodarone-induced thyrotoxicosis, as well as for diagnosis of congenital hypothyroidism."4.84Recombinant human thyrotropin in the management of thyroid disorders. ( Graf, H; Paz-Filho, GJ, 2008)
"To delineate the incidence, clinical features, diagnosis, and treatment options for amiodarone induced hyperthyroidism (AIH), we reviewed the medical records of ten patients with AIH."4.79Amiodarone induced hyperthyroidism: a case series and brief review of literature. ( Harjai, KJ; Licata, AA, 1996)
" He was diagnosed with atrial fibrillation 2 years previously and started on amiodarone and warfarin."3.80Amiodarone-induced thyrotoxicosis: type 1 or type 2? ( Khan, A; Puttanna, A; Raskauskiene, D, 2014)
"Amiodarone, an iodine-rich cardiac drug, may induce thyrotoxicosis (AIT), which can occur in patients with preexisting thyroid abnormalities and in subjects with apparently normal thyroid glands."3.69Serum interleukin-6 in amiodarone-induced thyrotoxicosis. ( Aghini-Lombardi, F; Bartalena, L; Braverman, LE; Brogioni, S; Grasso, L; Martino, E, 1994)
" We have distinguished four groups of patients: group A (n = 8): patients with true hyperthyroidism induced by drug administration; group B (n = 11): patients with mild hyperthyroid symptoms, but isolated thyroxine increase or dissociation between different indexes of thyroid function; group C (n = 5): patients with normal thyroid hormone levels, but increased TSH levels; group D (n = 6): patients who appeared really clinically euthyroid, with normal thyroid hormone levels and normal TSH response to TRH."3.67Evaluation of metabolic status in amiodarone-induced thyroid disorders: plasma coenzyme Q10 determination. ( Barbarino, A; Calabrò, F; De Marinis, L; Lippa, S; Littarru, GP; Mancini, A; Oradei, A; Sandric, S; Sciuto, R, 1989)
"Amiodarone iodine induced thyrotoxicosis occurs frequently in patients residing in areas of mild iodine deficiency and in patients with preexisting goiter."3.67Treatment of amiodarone associated thyrotoxicosis by simultaneous administration of potassium perchlorate and methimazole. ( Aghini-Lombardi, F; Baschieri, L; Braverman, LE; Lenziardi, M; Mariotti, S; Martino, E; Pinchera, A, 1986)
"Iodine induced hyperthyroidism is frequently observed in patients affected by euthyroid iodine deficient goiter when suddenly exposed to excess iodine."2.41Iodine excess and hyperthyroidism. ( Roti, E; Uberti, ED, 2001)
"Iodine is an essential element for thyroid hormone synthesis."2.41Iodine-Induced hypothyroidism. ( Georgopoulos, N; Kyriazopoulou, V; Markou, K; Vagenakis, AG, 2001)
"Transient hypothyroidism was observed in only two patients (5%) with AIH, though was not observed in TMNG."1.35Radioiodine therapy in patients with amiodarone-induced thyrotoxicosis (AIT). ( Bartkowiak, Z; Czarnywojtek, A; Czepczynski, R; Florek, E; Ruchala, M; Sowinski, J; Szczepanek, E; Wasko, R; Zamyslowska, H; Zgorzalewicz-Stachowiak, M, 2009)
"In methimazole-pretreated rats, the kinetic of DNA fragmentation was nearly the same; apoptosis increased for the first 6 hours and then decreased at 12 hours after KI administration."1.31Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo. ( Burikhanov, RB; Matsuzaki, S, 2000)
"Treatment with amiodarone was continued; however, therapy with L-thyroxin was initiated, followed by a complete regression of the goiter."1.28Goiter and hypothyroidism during re-treatment with amiodarone in a patient who previously experienced amiodarone-induced thyrotoxicosis. ( Ish-Shalom, S; Kaplan, J, 1991)
"Hyperthyroidism was a more frequent (9."1.27Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy. ( Aghini-Lombardi, F; Aronin, N; Fay, M; Haffajee, C; Lenziardi, M; Macchia, E; Martino, E; Pacchiarotti, A; Rajatanavin, R; Safran, M, 1984)
"Amiodarone is an anti-arrhythmic drug with a content of 39% Iodine."1.27Congenital hypothyroid goiter and amiodarone. ( De Schepper, J; De Wolf, D; Deneyer, M; Sacre-Smits, L; Smitz, J; Verhaaren, H, 1988)
"A physiological dose of iodine is necessary for thyroid hormonogenesis, but in pharmacological dosage it is a danger."1.26[Iatrogenic thyroid pathology]. ( Léger, AF; Savoie, JC, 1977)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199012 (48.00)18.7374
1990's4 (16.00)18.2507
2000's6 (24.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khan, A1
Puttanna, A1
Raskauskiene, D1
Rizzo, LF1
Mana, DL1
Bruno, OD1
Paz-Filho, GJ1
Graf, H1
Czarnywojtek, A1
Czepczynski, R1
Ruchala, M1
Wasko, R1
Zgorzalewicz-Stachowiak, M1
Szczepanek, E1
Zamyslowska, H1
Bartkowiak, Z1
Florek, E1
Sowinski, J1
Gómez, JJ1
Pomar, MD1
Casariego, AV1
Rodríguez, IC1
Zosin, I1
Balaş, M1
Martino, E3
Safran, M1
Aghini-Lombardi, F3
Rajatanavin, R1
Lenziardi, M2
Fay, M1
Pacchiarotti, A1
Aronin, N1
Macchia, E1
Haffajee, C1
Sanmartí, A1
Permanyer-Miralda, G1
Castellanos, JM1
Foz-Sala, M1
Galard, RM1
Soler-Soler, J1
Eason, RJ1
Croxson, MS1
Lim, TM1
Evans, MC1
Cooper, GJ1
Pickardt, R1
Bartalena, L1
Grasso, L1
Brogioni, S1
Braverman, LE2
Harjai, KJ1
Licata, AA1
Burikhanov, RB1
Matsuzaki, S1
Roti, E1
Uberti, ED1
Markou, K1
Georgopoulos, N1
Kyriazopoulou, V1
Vagenakis, AG1
Savoie, JC1
Léger, AF1
Kaplan, J1
Ish-Shalom, S1
Chow, CC1
Cockram, CS1
Mancini, A1
De Marinis, L1
Calabrò, F1
Sciuto, R1
Oradei, A1
Lippa, S1
Sandric, S1
Littarru, GP1
Barbarino, A1
De Rosa, G1
Corsello, SM1
Testa, A1
Cecchini, L1
Mariotti, S1
Baschieri, L1
Pinchera, A1
De Wolf, D1
De Schepper, J1
Verhaaren, H1
Deneyer, M1
Smitz, J1
Sacre-Smits, L1
Laurent, M1
Betremieux, P1
Biron, Y1
LeHelloco, A1
Samanta, A1
Jones, GR1
Burden, AC1
Barrie, WW1
Unger, J1

Reviews

7 reviews available for amiodarone and Goiter

ArticleYear
[Non-autoimmune thyroiditis].
    Medicina, 2014, Volume: 74, Issue:6

    Topics: Amiodarone; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diagnosis, Differential; Gluco

2014
Recombinant human thyrotropin in the management of thyroid disorders.
    Expert opinion on biological therapy, 2008, Volume: 8, Issue:11

    Topics: Amiodarone; Clinical Trials as Topic; Goiter; Humans; Iodine Radioisotopes; Neoplasm Metastasis; Rec

2008
Amiodarone induced hyperthyroidism: a case series and brief review of literature.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:11 Pt 1

    Topics: Amiodarone; Female; Goiter; Humans; Hyperthyroidism; Male; Middle Aged; Thyroid Hormones; Time Facto

1996
Iodine excess and hyperthyroidism.
    Thyroid : official journal of the American Thyroid Association, 2001, Volume: 11, Issue:5

    Topics: Amiodarone; Endemic Diseases; Environmental Exposure; Goiter; Graves Disease; Hyperthyroidism; Iodin

2001
Iodine-Induced hypothyroidism.
    Thyroid : official journal of the American Thyroid Association, 2001, Volume: 11, Issue:5

    Topics: Amiodarone; Drug Synergism; Female; Goiter; Humans; Hypothyroidism; Infant, Newborn; Iodides; Iodine

2001
Thyroid disorders induced by lithium and amiodarone: an overview.
    Adverse drug reactions and acute poisoning reviews, 1990,Winter, Volume: 9, Issue:4

    Topics: Amiodarone; Animals; Goiter; Humans; Hypothyroidism; Lithium; Thyroid Diseases; Thyroid Hormones; Th

1990
[Amiodarone and thyroid function].
    La Clinica terapeutica, 1987, Nov-15, Volume: 123, Issue:3

    Topics: Amiodarone; Goiter; Humans; Hypothyroidism; Thyroid Gland; Thyroid Hormones; Thyronines

1987

Other Studies

18 other studies available for amiodarone and Goiter

ArticleYear
Amiodarone-induced thyrotoxicosis: type 1 or type 2?
    BMJ case reports, 2014, Oct-27, Volume: 2014

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Atrial Fibrillation; Carbimazole; Gluc

2014
Radioiodine therapy in patients with amiodarone-induced thyrotoxicosis (AIT).
    Neuro endocrinology letters, 2009, Volume: 30, Issue:2

    Topics: Aged; Aged, 80 and over; Amiodarone; Female; Follow-Up Studies; Goiter; Humans; Hypothyroidism; Iodi

2009
[Selective pituitary resistance to thyroid hormone in a patient treated with amiodarone].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Diabetes Mellitus, Type 2; Feedback, Physio

2009
Amiodarone-induced thyroid dysfunction in an iodine-replete area: epidemiological and clinical data.
    Endokrynologia Polska, 2012, Volume: 63, Issue:1

    Topics: Aged; Amiodarone; Analysis of Variance; Anti-Arrhythmia Agents; Female; Goiter; Humans; Hypothyroidi

2012
Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy.
    Annals of internal medicine, 1984, Volume: 101, Issue:1

    Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Goiter; Heart Diseases; Humans; Hyperthyroidism; Hypot

1984
Chronic administration of amiodarone and thyroid function: a follow-up study.
    American heart journal, 1984, Volume: 108, Issue:5

    Topics: Adult; Aged; Amiodarone; Benzofurans; Chronic Disease; Coronary Disease; Female; Follow-Up Studies;

1984
Goitre and thyroid dysfunction during chronic amiodarone treatment.
    The New Zealand medical journal, 1984, Apr-11, Volume: 97, Issue:753

    Topics: Adult; Amiodarone; Benzofurans; Female; Goiter; Humans; Male; Thyroid Diseases; Thyroid Function Tes

1984
[Iodine-induced hyperthyroidism].
    Deutsche medizinische Wochenschrift (1946), 1982, Aug-20, Volume: 107, Issue:33

    Topics: Amiodarone; Goiter; Humans; Hyperthyroidism; Iodine; Ophthalmic Solutions; Povidone-Iodine

1982
Serum interleukin-6 in amiodarone-induced thyrotoxicosis.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Cross-Sectional Studies; Diagnosis, Differential; Goiter

1994
Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo.
    Thyroid : official journal of the American Thyroid Association, 2000, Volume: 10, Issue:2

    Topics: Amiodarone; Animals; Antithyroid Agents; Apoptosis; Diiodotyrosine; DNA Fragmentation; Goiter; Male;

2000
[Iatrogenic thyroid pathology].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Jun-23, Volume: 53, Issue:24

    Topics: Amiodarone; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Thyroid Diseases

1977
Goiter and hypothyroidism during re-treatment with amiodarone in a patient who previously experienced amiodarone-induced thyrotoxicosis.
    The American journal of medicine, 1991, Volume: 90, Issue:6

    Topics: Amiodarone; Female; Goiter; Humans; Hypothyroidism; Middle Aged; Tachycardia, Supraventricular; Thyr

1991
Evaluation of metabolic status in amiodarone-induced thyroid disorders: plasma coenzyme Q10 determination.
    Journal of endocrinological investigation, 1989, Volume: 12, Issue:8

    Topics: Adult; Aged; Amiodarone; Female; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged;

1989
Treatment of amiodarone associated thyrotoxicosis by simultaneous administration of potassium perchlorate and methimazole.
    Journal of endocrinological investigation, 1986, Volume: 9, Issue:3

    Topics: Adult; Aged; Amiodarone; Drug Synergism; Drug Therapy, Combination; Female; Goiter; Humans; Male; Me

1986
Congenital hypothyroid goiter and amiodarone.
    Acta paediatrica Scandinavica, 1988, Volume: 77, Issue:4

    Topics: Adult; Amiodarone; Congenital Hypothyroidism; Female; Goiter; Humans; Hypothyroidism; Infant; Infant

1988
Neonatal hypothyroidism after treatment by amiodarone during pregnancy.
    The American journal of cardiology, 1987, Oct-01, Volume: 60, Issue:10

    Topics: Adult; Amiodarone; Female; Fetal Diseases; Goiter; Heart Failure; Humans; Infant, Newborn; Maternal-

1987
Thoracic inlet compression due to amiodarone induced goitre.
    Postgraduate medical journal, 1985, Volume: 61, Issue:713

    Topics: Airway Obstruction; Amiodarone; Benzofurans; Goiter; Humans; Male; Middle Aged; Thyroidectomy

1985
[Thyroid pathology iatrogenically induced by iodinated products].
    Revue medicale de Bruxelles, 1985, Volume: 6, Issue:6

    Topics: Amiodarone; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Thyroid Diseases; Thyroid Hormo

1985