amiodarone has been researched along with Blindness in 7 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Blindness: The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The optic nerve is quite vulnerable to the toxic effect of drugs." | 2.44 | [Toxicity of recent and less recent drugs on the optic nerve. Does Viagra cause blindness?]. ( Cordonnier, M, 2007) |
| "Amiodarone is a commonly prescribed and one of the most effective anti-arrhythmic drugs available." | 1.39 | Bilateral optic neuropathy and permanent loss of vision after treatment with amiodarone. ( Falck, A; Hautala, N; Hurskainen, M; Kervinen, M, 2013) |
| "Amiodarone therapy was then discontinued, but there was no considerable improvement and after 6 weeks visual loss occurred in the left eye as well." | 1.31 | [First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?]. ( Gerke, E; Uebermuth, CA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kervinen, M | 1 |
| Falck, A | 1 |
| Hurskainen, M | 1 |
| Hautala, N | 1 |
| Knudsen, A | 1 |
| Pelletier, AL | 1 |
| Thomas, J | 1 |
| Shaw, FR | 1 |
| Passman, RS | 1 |
| Bennett, CL | 1 |
| Purpura, JM | 1 |
| Kapur, R | 1 |
| Johnson, LN | 1 |
| Raisch, DW | 1 |
| West, DP | 1 |
| Edwards, BJ | 1 |
| Belknap, SM | 1 |
| Liebling, DB | 1 |
| Fisher, MJ | 1 |
| Samaras, AT | 1 |
| Jones, LG | 1 |
| Tulas, KM | 1 |
| McKoy, JM | 1 |
| Ciechanowski, PP | 1 |
| Töteberg-Harms, M | 1 |
| Stürmer, J | 1 |
| Kunz, M | 1 |
| Landau, K | 1 |
| Sturm, V | 1 |
| Uebermuth, CA | 1 |
| Gerke, E | 1 |
| Cordonnier, M | 1 |
2 reviews available for amiodarone and Blindness
| Article | Year |
|---|---|
Amiodarone-associated optic neuropathy: a critical review.
Topics: Amiodarone; Anti-Arrhythmia Agents; Blindness; Humans; Optic Nerve Diseases | 2012 |
[Toxicity of recent and less recent drugs on the optic nerve. Does Viagra cause blindness?].
Topics: Acetamides; Amiodarone; Blindness; Ethambutol; Humans; Immunosuppressive Agents; Interferon-alpha; L | 2007 |
5 other studies available for amiodarone and Blindness
| Article | Year |
|---|---|
Bilateral optic neuropathy and permanent loss of vision after treatment with amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Blindness; Female; Humans; Optic Nerve Diseases; Papillede | 2013 |
Short-term treatment with oral amiodarone resulting in bilateral optic neuropathy and permanent blindness.
Topics: Administration, Oral; Aftercare; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Blin | 2017 |
Vision loss in older persons.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Asthmatic Agents; Blindness; Cataract; Causality; Comorbid | 2009 |
Bilateral optic neuropathy after short-term treatment with intravenous amiodarone.
Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Blindness; Humans; Injections, Intrave | 2012 |
[First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blindness; Dose-Response Relationshi | 2002 |