alpha-chymotrypsin and Agammaglobulinemia

alpha-chymotrypsin has been researched along with Agammaglobulinemia* in 2 studies

Other Studies

2 other study(ies) available for alpha-chymotrypsin and Agammaglobulinemia

ArticleYear
Granulocyte phagocytosis and killing virulent and avirulent serotypes of Streptococcus pneumoniae.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:2

    Five commonly isolated Streptococcus pneumoniae serotypes (3, 6, 14, 19, and 23) and five rarely found serotypes (31, 35, 36, 42, and 43) were compared to elucidate whether increased resistance against granulocyte phagocytosis and killing could explain the restricted number of pneumococcal serotypes found in infections. There was a great variation in sensitivity among the serotypes to granulocyte killing. No consistent pattern was found when pathogenicity and resistance to granulocytes were compared. The results do not indicate that the increased tendency of pathogenic pneumococcal serotypes to cause infections is due to increased resistance to granulocytes. Monocyte killing of some pneumococal serotypes (6, 19, 23, 35, and 43) was also studied and found very similar to granulocyte killing. Defective granulocyte kiling of encapsulated pneumococci was due to impaired phagocytosis. Moreover, no correlation was found between the sensitivity of the serotypes to isolated intragranulocytic microbial systems (i.e., MPO, hydrogen peroxide, or CCP) and the sensitivity to killing by intact granulocytes or pathogenicity. The significance of both the classical and alternative complement pathways for pneumococcal opsonization was indicated by reduced, the residual phagocytosis in C2-deficient and MgEGTA-chelated serum.

    Topics: Agammaglobulinemia; Blood Bactericidal Activity; Chymotrypsin; Complement C2; Egtazic Acid; Granulocytes; Humans; In Vitro Techniques; Monocytes; Peroxidase; Phagocytosis; Serotyping; Streptococcus pneumoniae

1982
Human lymphocyte mitogenic factor: synthesis by sensitized thymus-derived lymphocytes, dependence of expression on the presence of antigen.
    Cellular immunology, 1974, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Agammaglobulinemia; Amylases; Animals; Antigens, Bacterial; Child; Child, Preschool; Chymotrypsin; Dactinomycin; DNA; Female; Fibroblasts; Heparin; Humans; Infant, Newborn; Iodine Radioisotopes; Lymphokines; Mice; Mice, Inbred C57BL; Mitosis; Pregnancy; Serum Albumin, Bovine; T-Lymphocytes; Tetanus Toxoid; Thymidine; Tritium; Trypsin

1974
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