aldosterone and Pulmonary Hypertension
aldosterone has been researched along with Pulmonary Hypertension in 29 studies
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Since the renin-angiotensin-aldosterone system and atrial natriuretic factor are directly involved in the regulation of hemodynamics and structural alterations in the circulatory system, the interest of investigators in the observed changes in this system during exogenous hypoxia and the resultant development of high-altitude pulmonary hypertension is quite understandable." | 7.69 | Atrial natriuretic factor in high-altitude pulmonary hypertension: the influence of acute hypoxia on plasma atrial natriuretic factor, renin, and aldosterone concentrations in highlanders with initially normal or elevated pulmonary artery pressure and wit ( Batyraliev, TA; Birand, A; Kudaiberdieva, GZ; Niyazova, ZA; Soodanbekova, GK, 1995) |
"To investigate the physiological role of atrial natriuretic factor (ANF) in patients with hypoxic pulmonary hypertension secondary to chronic obstructive lung disease (COLD), we infused synthetic alpha-human ANF in seven such patients, and investigated the physiological correlates to circulating peptide levels in 24 patients with COLD." | 7.67 | Atrial natriuretic factor in chronic obstructive lung disease with pulmonary hypertension. Physiological correlates and response to peptide infusion. ( Adnot, S; Andrivet, P; Braquet, P; Brun-Buisson, C; Chabrier, PE; Piquet, J; Plas, P; Roudot-Thoraval, F, 1989) |
"MRAs are a recognized treatment for heart failure and hypertension." | 6.66 | Aldosterone and Mineralocorticoid Receptor Antagonists on Pulmonary Hypertension and Right Ventricular Failure: A Review. ( Mohammadpour, AH; Omidkhoda, N; Sahebkar, A; Sathyapalan, T; Vakilian, F, 2020) |
" We evaluated the efficacy of MR antagonism by spironolactone in two experimental PH models; mouse chronic hypoxia-induced PH (prevention model) and rat monocrotaline-induced PH (prevention and treatment models)." | 3.79 | Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension. ( Fanburg, BL; Hill, NS; Jaffe, IZ; Preston, IR; Sagliani, KD; Warburton, RR, 2013) |
"Since the renin-angiotensin-aldosterone system and atrial natriuretic factor are directly involved in the regulation of hemodynamics and structural alterations in the circulatory system, the interest of investigators in the observed changes in this system during exogenous hypoxia and the resultant development of high-altitude pulmonary hypertension is quite understandable." | 3.69 | Atrial natriuretic factor in high-altitude pulmonary hypertension: the influence of acute hypoxia on plasma atrial natriuretic factor, renin, and aldosterone concentrations in highlanders with initially normal or elevated pulmonary artery pressure and wit ( Batyraliev, TA; Birand, A; Kudaiberdieva, GZ; Niyazova, ZA; Soodanbekova, GK, 1995) |
"Administration of iopromide for pulmonary angiography in patients with pulmonary hypertension resulted in no appreciable hemodynamic alterations associated with the observed changes in atrial natriuretic peptide, antidiuretic hormone, and renin." | 3.69 | Pulmonary hypertension. Response of vasoactive peptides to a nonionic contrast medium in patients undergoing pulmonary angiography. ( Flueckiger, F; Horina, J; Preidler, K; Riepl, T; Saeed, M; Stiskal, MA; Szolar, DH; Watzinger, N, 1995) |
"Angiotensin II (AT II), plasma renin activity (PRA) and aldosterone (Ald) were determined at 8:00 AM in sitting position for 30 minutes in 12 heathy nonsmokers, 50-60 years old, with normal functions of small airway, normal FEV1 and lung volumes, and in 23 patients with chronic bronchitis with or without emphysema." | 3.69 | [RAAS changes due to dysfunction of pulmonary ventilation]. ( Lin, Y; Ma, Y; Sun, M, 1996) |
"To investigate the physiological role of atrial natriuretic factor (ANF) in patients with hypoxic pulmonary hypertension secondary to chronic obstructive lung disease (COLD), we infused synthetic alpha-human ANF in seven such patients, and investigated the physiological correlates to circulating peptide levels in 24 patients with COLD." | 3.67 | Atrial natriuretic factor in chronic obstructive lung disease with pulmonary hypertension. Physiological correlates and response to peptide infusion. ( Adnot, S; Andrivet, P; Braquet, P; Brun-Buisson, C; Chabrier, PE; Piquet, J; Plas, P; Roudot-Thoraval, F, 1989) |
"The hemodynamic changes and plasma renin activity (PRA), angiotensin II (ATII), aldosterone (Ald) levels in 38 COPD patients with or without pulmonary hypertension were studied." | 3.67 | [Hemodynamic changes and their relationship with the renin-angiotensin-aldosterone system in chronic obstructive pulmonary disease]. ( Zen, GB, 1989) |
"MRAs are a recognized treatment for heart failure and hypertension." | 2.66 | Aldosterone and Mineralocorticoid Receptor Antagonists on Pulmonary Hypertension and Right Ventricular Failure: A Review. ( Mohammadpour, AH; Omidkhoda, N; Sahebkar, A; Sathyapalan, T; Vakilian, F, 2020) |
"Hyperaldosteronism has emerged as a promoter of pulmonary vascular disease in experimental animal models of PAH; however, the extent to which hyperaldosteronism is associated with PAH in patients is unknown." | 1.39 | Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study. ( Landzberg, MJ; Leopold, JA; Loscalzo, J; Maron, BA; Opotowsky, AR; Waxman, AB, 2013) |
"Poor survival in pulmonary hypertension is known to be associated with unfavorable hemodynamic variables, including elevated right atrial pressure, elevated mean pulmonary artery pressure, and low cardiac index." | 1.32 | Plasma volume and outcome in pulmonary hypertension. ( Armstrong, R; Fouad-Tarazi, F; James, KB; Stelmach, K; Young, JB, 2003) |
"Aldosterone excretion was in HL with EH substantially lower, and sodium excretion higher, than in a comparable group of lowland inhabitants." | 1.27 | Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude. ( Dzhumagulova, AS; Meimanaliev, TS; Mirrakhimov, MM; Murataliev, TM; Rafibekova, ZhS; Shatemirova, KK, 1985) |
Research
Studies (29)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (24.14) | 18.7374 |
1990's | 7 (24.14) | 18.2507 |
2000's | 3 (10.34) | 29.6817 |
2010's | 10 (34.48) | 24.3611 |
2020's | 2 (6.90) | 2.80 |
Authors
Authors | Studies |
---|---|
Mamazhakypov, A | 1 |
Hein, L | 1 |
Lother, A | 1 |
Omidkhoda, N | 1 |
Vakilian, F | 1 |
Mohammadpour, AH | 1 |
Sathyapalan, T | 1 |
Sahebkar, A | 1 |
Preston, IR | 1 |
Sagliani, KD | 1 |
Warburton, RR | 1 |
Hill, NS | 1 |
Fanburg, BL | 1 |
Jaffe, IZ | 1 |
Maron, BA | 5 |
Leopold, JA | 4 |
Calvier, L | 1 |
Legchenko, E | 1 |
Grimm, L | 1 |
Sallmon, H | 1 |
Hatch, A | 1 |
Plouffe, BD | 1 |
Schroeder, C | 1 |
Bauersachs, J | 1 |
Murthy, SK | 1 |
Hansmann, G | 1 |
Aghamohammadzadeh, R | 1 |
Zhang, YY | 2 |
Stephens, TE | 1 |
Arons, E | 1 |
Zaman, P | 1 |
Polach, KJ | 1 |
Matar, M | 1 |
Yung, LM | 1 |
Yu, PB | 1 |
Bowman, FP | 1 |
Opotowsky, AR | 2 |
Waxman, AB | 2 |
Loscalzo, J | 3 |
Bansal, S | 1 |
Badesch, D | 1 |
Bull, T | 1 |
Schrier, RW | 1 |
Farber, HW | 1 |
Walkey, AJ | 1 |
Alikhan, MM | 1 |
Yamanaka, R | 1 |
Otsuka, F | 1 |
Nakamura, K | 1 |
Yamashita, M | 1 |
Otani, H | 1 |
Takeda, M | 1 |
Matsumoto, Y | 1 |
Kusano, KF | 1 |
Ito, H | 1 |
Makino, H | 1 |
Chabot, A | 1 |
Jiang, BH | 1 |
Shi, Y | 1 |
Tardif, JC | 1 |
Dupuis, J | 1 |
White, K | 1 |
Chan, SY | 1 |
Handy, DE | 1 |
Mahoney, CE | 1 |
Landzberg, MJ | 1 |
HAYSLETT, JP | 1 |
FLINN, RB | 1 |
MULROW, PJ | 1 |
James, KB | 1 |
Stelmach, K | 1 |
Armstrong, R | 1 |
Young, JB | 1 |
Fouad-Tarazi, F | 1 |
Ciarka, A | 1 |
Vachièry, JL | 1 |
Houssière, A | 1 |
Gujic, M | 1 |
Stoupel, E | 1 |
Velez-Roa, S | 1 |
Naeije, R | 1 |
van de Borne, P | 1 |
Ikram, H | 1 |
Maslowski, AH | 1 |
Nicholls, MG | 1 |
Espiner, EA | 1 |
Hull, FT | 1 |
Alekseev, VG | 1 |
Tikhomirov, ES | 1 |
Gerasimov, GM | 1 |
Soodanbekova, GK | 1 |
Batyraliev, TA | 1 |
Niyazova, ZA | 1 |
Kudaiberdieva, GZ | 1 |
Birand, A | 1 |
Szolar, DH | 1 |
Saeed, M | 1 |
Flueckiger, F | 1 |
Preidler, K | 1 |
Stiskal, MA | 1 |
Watzinger, N | 1 |
Riepl, T | 1 |
Horina, J | 1 |
Kiely, DG | 1 |
Cargill, RI | 1 |
Wheeldon, NM | 1 |
Coutie, WJ | 1 |
Lipworth, BJ | 1 |
Lin, Y | 1 |
Sun, M | 1 |
Ma, Y | 1 |
Martyniuk, TV | 1 |
Chazova, IE | 1 |
Masenko, VP | 1 |
Volkov, VN | 1 |
Belenkov, IuN | 1 |
Oelz, O | 1 |
Maggiorini, M | 1 |
Ritter, M | 1 |
Noti, C | 1 |
Waber, U | 1 |
Vock, P | 1 |
Bärtsch, P | 1 |
Cardoso, PF | 1 |
Hsieh, CM | 1 |
Daniel, L | 1 |
Yokomise, H | 1 |
Kato, H | 1 |
Strangemore, BL | 1 |
Miller, JD | 1 |
Logan, AG | 1 |
Rakowski, H | 1 |
Patterson, GA | 1 |
Adnot, S | 1 |
Andrivet, P | 1 |
Chabrier, PE | 1 |
Piquet, J | 1 |
Plas, P | 1 |
Braquet, P | 1 |
Roudot-Thoraval, F | 1 |
Brun-Buisson, C | 1 |
Liu, LS | 1 |
Cheng, HY | 1 |
Chin, WJ | 1 |
Jin, HK | 1 |
Oparil, S | 1 |
Zen, GB | 1 |
Mirrakhimov, MM | 1 |
Rafibekova, ZhS | 1 |
Dzhumagulova, AS | 1 |
Meimanaliev, TS | 1 |
Murataliev, TM | 1 |
Shatemirova, KK | 1 |
Clinical Trials (2)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Biomarkers in Congenital Heart Diseases and Pulmonary Arterial Hypertension[NCT04130243] | 380 participants (Anticipated) | Observational [Patient Registry] | 2017-12-05 | Active, not recruiting | |||
Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru (ANDES Study)[NCT05524987] | 1,068 participants (Anticipated) | Interventional | 2022-11-30 | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Reviews
4 reviews available for aldosterone and Pulmonary Hypertension
Article | Year |
---|---|
Mineralocorticoid receptors in pulmonary hypertension and right heart failure: From molecular biology to therapeutic targeting.
Topics: Aldosterone; Animals; Endothelial Cells; Heart Failure; Humans; Hypertension, Pulmonary; Mice; Miner | 2022 |
Aldosterone and Mineralocorticoid Receptor Antagonists on Pulmonary Hypertension and Right Ventricular Failure: A Review.
Topics: Aldosterone; Heart Failure; Humans; Hypertension, Pulmonary; Mineralocorticoid Receptor Antagonists; | 2020 |
Emerging Concepts in the Molecular Basis of Pulmonary Arterial Hypertension: Part II: Neurohormonal Signaling Contributes to the Pulmonary Vascular and Right Ventricular Pathophenotype of Pulmonary Arterial Hypertension.
Topics: Aldosterone; Fibrosis; Heart Ventricles; Humans; Hypertension, Pulmonary; Neurotransmitter Agents; P | 2015 |
[Pathophysiology, prevention and therapy of altitude pulmonary edema].
Topics: Aldosterone; Altitude Sickness; Cell Membrane Permeability; Epinephrine; Humans; Hypertension, Pulmo | 1992 |
Trials
3 trials available for aldosterone and Pulmonary Hypertension
Article | Year |
---|---|
Role of vasopressin and aldosterone in pulmonary arterial hypertension: A pilot study.
Topics: Aldosterone; Health Status Indicators; Humans; Hypertension, Pulmonary; Mineralocorticoid Receptor A | 2009 |
Atrial septostomy decreases sympathetic overactivity in pulmonary arterial hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Female; Heart Atria; Heart Rate; Heart Septum; H | 2007 |
Haemodynamic and endocrine effects of type 1 angiotensin II receptor blockade in patients with hypoxaemic cor pulmonale.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphen | 1997 |
Other Studies
22 other studies available for aldosterone and Pulmonary Hypertension
Article | Year |
---|---|
Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension.
Topics: Aldosterone; Animals; Arterial Pressure; Body Weight; Cardiac Output; Cell Proliferation; Fibrosis; | 2013 |
The quest for biomarker discovery in pulmonary arterial hypertension: the right takes lessons from the left.
Topics: Aldosterone; Female; Galectin 3; Humans; Hypertension, Pulmonary; Male | 2016 |
Galectin-3 and aldosterone as potential tandem biomarkers in pulmonary arterial hypertension.
Topics: Adult; Aged; Aldosterone; Biomarkers; Blood Proteins; Case-Control Studies; Enzyme-Linked Immunosorb | 2016 |
Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension.
Topics: Adaptor Proteins, Signal Transducing; Aldosterone; Animals; Apoptosis; Cell Proliferation; Cell Surv | 2016 |
The role of aldosterone in pulmonary venous hypertension.
Topics: Aldosterone; Humans; Hypertension, Pulmonary; Renin-Angiotensin System; Risk Factors; Venous Pressur | 2010 |
Involvement of the bone morphogenetic protein system in endothelin- and aldosterone-induced cell proliferation of pulmonary arterial smooth muscle cells isolated from human patients with pulmonary arterial hypertension.
Topics: Aldosterone; Analysis of Variance; Blotting, Western; Bone Morphogenetic Protein Receptors, Type II; | 2010 |
Role of aldosterone on lung structural remodelling and right ventricular function in congestive heart failure.
Topics: Aldosterone; Animals; Cell Proliferation; Echocardiography; Heart Failure; Hypertension, Pulmonary; | 2011 |
Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension.
Topics: Aldosterone; Animals; Cells, Cultured; Cysteine; Disease Models, Animal; Endothelial Cells; Endothel | 2012 |
Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Cardiac Catheterization; Cardiac Output, Low; Case-Cont | 2013 |
Hypertension and increased aldosterone excretion associated with unilateral renal artery stenosis.
Topics: Aldosterone; Humans; Hyperparathyroidism; Hypertension; Hypertension, Pulmonary; Renal Artery Obstru | 1963 |
Plasma volume and outcome in pulmonary hypertension.
Topics: Adult; Aldosterone; Arginine Vasopressin; Atrial Natriuretic Factor; Catheterization, Swan-Ganz; Fea | 2003 |
Haemodynamic and hormonal effects of captopril in primary pulmonary hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Hemodynamics; Humans; H | 1982 |
[Role of the angiotensin-aldosterone mechanism in the formation of Pulmonogenic arterial hypertension].
Topics: Aldosterone; Angiotensin I; Angiotensins; Chronic Disease; Humans; Hypertension; Hypertension, Pulmo | 1982 |
Atrial natriuretic factor in high-altitude pulmonary hypertension: the influence of acute hypoxia on plasma atrial natriuretic factor, renin, and aldosterone concentrations in highlanders with initially normal or elevated pulmonary artery pressure and wit
Topics: Acute Disease; Adolescent; Adult; Aldosterone; Altitude Sickness; Atrial Natriuretic Factor; Humans; | 1995 |
Pulmonary hypertension. Response of vasoactive peptides to a nonionic contrast medium in patients undergoing pulmonary angiography.
Topics: Adult; Aged; Aldosterone; Anaphylaxis; Angiography, Digital Subtraction; Angiotensin II; Atrial Natr | 1995 |
[RAAS changes due to dysfunction of pulmonary ventilation].
Topics: Aldosterone; Angiotensin II; Bronchitis; Female; Humans; Hypertension, Pulmonary; Lung Diseases, Obs | 1996 |
[Activity of renin-angiotensin-aldosterone system (RAAS) and vasopressin level in patients with primary pulmonary hypertension].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biomarkers; Female; Humans; Hypertension, Pulmonary; | 1998 |
Plasma atrial natriuretic factor concentrations in a canine model of right heart pressure overload.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Dogs; Edema; Heart Atria; Hypertens | 1991 |
Atrial natriuretic factor in chronic obstructive lung disease with pulmonary hypertension. Physiological correlates and response to peptide infusion.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output; Female; Heart R | 1989 |
Atrial natriuretic peptide lowers pulmonary arterial pressure in patients with high altitude disease.
Topics: Aldosterone; Altitude Sickness; Atrial Natriuretic Factor; Hypertension, Pulmonary; Hypoxia; Renin | 1989 |
[Hemodynamic changes and their relationship with the renin-angiotensin-aldosterone system in chronic obstructive pulmonary disease].
Topics: Aldosterone; Angiotensin II; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, O | 1989 |
Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude.
Topics: Adult; Age Factors; Aldosterone; Alkalosis, Respiratory; Altitude; Altitude Sickness; Cardiomegaly; | 1985 |