Page last updated: 2024-11-08

alanine and Ulcer

alanine has been researched along with Ulcer in 11 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin treatment induced intestinal ulcers that gradually healed after treatment."7.80Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. ( Akiba, Y; Engel, E; Guth, PH; Higashiyama, M; Higuchi, K; Inoue, T; Kaji, I; Kaunitz, JD; Rudenkyy, S, 2014)
" This study aims to determine small intestinal alanine absorption and cytokine expression in a novel model of colonic ulceration induced by electro-cautery."3.81Electrocautery-induced localized colonic injury elicits increased levels of pro-inflammatory cytokines in small bowel and decreases jejunal alanine absorption. ( Barada, K; Mourad, FH; Noutsi, B; Saadé, NE, 2015)
"Intestinal ulceration and bleeding were induced in Wistar rats by oral administration of naproxen."3.81Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota. ( Bercik, P; Blackler, RW; Manko, A; Motta, JP; Surette, MG; Wallace, JL; Workentine, M, 2015)
"Indomethacin treatment induced intestinal ulcers that gradually healed after treatment."3.80Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. ( Akiba, Y; Engel, E; Guth, PH; Higashiyama, M; Higuchi, K; Inoue, T; Kaji, I; Kaunitz, JD; Rudenkyy, S, 2014)
"Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers."3.11The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study. ( Choi, YJ; Ha, YJ; Kang, EH; Kim, HS; Kim, KJ; Kim, N; Lee, DH; Lee, YJ; Liu, F; Oh, DJ; Park, YS; Shin, CM; Yoon, H, 2022)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Oh, DJ1
Yoon, H1
Kim, HS1
Choi, YJ1
Shin, CM1
Park, YS1
Kim, N2
Lee, DH1
Ha, YJ1
Kang, EH1
Lee, YJ1
Kim, KJ1
Liu, F1
Jung, DH1
Park, JC1
Lee, YC1
Lee, SK1
Shin, SK1
Chung, H1
Park, JJ1
Kim, JH1
Youn, YH1
Park, H1
Xu, N1
Zhang, C1
Jing, L1
Mou, S1
Cao, X1
Yu, Z1
Fujimoto, A1
Uraoka, T1
Yahagi, N1
Dong, T1
Zhao, L1
Liu, L1
Fan, Z1
Inoue, T1
Higashiyama, M1
Kaji, I1
Rudenkyy, S1
Higuchi, K1
Guth, PH1
Engel, E1
Kaunitz, JD1
Akiba, Y1
Barada, K1
Mourad, FH1
Noutsi, B1
Saadé, NE1
Blackler, RW1
Motta, JP1
Manko, A1
Workentine, M1
Bercik, P1
Surette, MG1
Wallace, JL1
Otani, K1
Tanigawa, T1
Watanabe, T1
Shimada, S1
Nadatani, Y1
Nagami, Y1
Tanaka, F1
Kamata, N1
Yamagami, H1
Shiba, M1
Tominaga, K1
Fujiwara, Y1
Arakawa, T1
Kawai, T1
Yamagishi, T1
Goto, S1
Takagi, T1
Naito, Y1
Uchiyama, K1
Okuda, T1
Mizushima, K1
Suzuki, T1
Handa, O1
Ishikawa, T1
Yagi, N1
Kokura, S1
Ichikawa, H1
Yoshikawa, T1

Reviews

1 review available for alanine and Ulcer

ArticleYear
Microbiota Plays a Key Role in Non-Steroidal Anti-Inflammatory Drug-Induced Small Intestinal Damage.
    Digestion, 2017, Volume: 95, Issue:1

    Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Gastrointestinal Microbiome; Hu

2017

Trials

3 trials available for alanine and Ulcer

ArticleYear
The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study.
    The Korean journal of internal medicine, 2022, Volume: 37, Issue:6

    Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Humans; Intestinal Diseases; Pilot Projects; Ulcer

2022
Comparison of the Efficacy of Polaprezinc Plus Proton Pump Inhibitor and Rebamipide Plus Proton Pump Inhibitor Treatments for Endoscopic Submucosal Dissection-induced Ulcers.
    Journal of clinical gastroenterology, 2021, 03-01, Volume: 55, Issue:3

    Topics: Alanine; Anti-Ulcer Agents; Carnosine; Drug Therapy, Combination; Endoscopic Mucosal Resection; Huma

2021
Circadian variations of gastrointestinal mucosal damage detected with transnasal endoscopy in apparently healthy subjects treated with low-dose aspirin (ASA) for a short period.
    Journal of atherosclerosis and thrombosis, 2009, Volume: 16, Issue:3

    Topics: Adult; Alanine; Aspirin; Circadian Rhythm; Double-Blind Method; Endoscopy; Female; Gastric Mucosa; H

2009

Other Studies

7 other studies available for alanine and Ulcer

ArticleYear
Protective effect and mechanism of rebamipide on NSAIDs associated small bowel injury.
    International immunopharmacology, 2021, Volume: 90

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Claudin-1; Cytokines; Diclofenac; Disease

2021
Response.
    Gastrointestinal endoscopy, 2019, Volume: 89, Issue:3

    Topics: Alanine; Endoscopic Mucosal Resection; Humans; Quinolones; Ulcer

2019
Submucosal injection materials other than mucosal lift.
    Gastrointestinal endoscopy, 2019, Volume: 89, Issue:3

    Topics: Alanine; Endoscopic Mucosal Resection; Humans; Mucous Membrane; Quinolones; Ulcer

2019
Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:6

    Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipeptidyl-Peptidas

2014
Electrocautery-induced localized colonic injury elicits increased levels of pro-inflammatory cytokines in small bowel and decreases jejunal alanine absorption.
    Cytokine, 2015, Volume: 71, Issue:1

    Topics: Alanine; Animals; Colitis; Colon; Cytokines; Disease Models, Animal; Duodenum; Electrocoagulation; I

2015
Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota.
    British journal of pharmacology, 2015, Volume: 172, Issue:4

    Topics: Alanine; Allyl Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Cell Line; Cycloox

2015
Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution.
    World journal of gastroenterology, 2011, Sep-07, Volume: 17, Issue:33

    Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Line; Colon; Epithelial Cells; Intestinal Mucosa; Male; Qu

2011