alanine and Diarrhea
alanine has been researched along with Diarrhea in 17 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Results of these studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C." | 7.74 | Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets. ( Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH, 2008) |
| "20 trial randomized patients with K-RAS wild-type, chemotherapy-refractory, metastatic colorectal cancer to receive cetuximab (CET) plus brivanib alaninate (BRIV) or CET plus placebo (CET/placebo)." | 5.19 | Quality of life in patients with K-RAS wild-type colorectal cancer: the CO.20 phase 3 randomized trial. ( Alcindor, T; Au, HJ; Easaw, JC; El-Tahche, F; Jeffery, M; Jonker, DJ; Kotb, R; Moore, MJ; Ng, S; O'Callaghan, CJ; Ringash, J; Sabesan, S; Salim, M; Shannon, J; Shapiro, JD; Siu, LL; Strickland, A; Tu, D; Walters, I; Zalcberg, JR, 2014) |
| "Oral rehydration solution containing L-alanine was considerably better than standard oral rehydration solution at reducing the severity of symptoms and the need for fluid of male patients with diarrhoea associated with V cholerae and enterotoxigenic E coli." | 5.06 | Oral rehydration formula containing alanine and glucose for treatment of diarrhoea: a controlled trial. ( Alam, AN; Islam, A; Mazumder, RN; Patra, FC; Sack, DA, 1989) |
| "Results of these studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C." | 3.74 | Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets. ( Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH, 2008) |
| "We conclude that hypoglycemia is a major cause of death in association with diarrhea." | 1.28 | Hypoglycemia during diarrhea in childhood. Prevalence, pathophysiology, and outcome. ( Azad, AK; Bennish, ML; Phillips, RE; Rahman, O, 1990) |
Research
Studies (17)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Carnevale, S | 1 |
| Beretta, P | 1 |
| Morbini, P | 1 |
| Zekarias, A | 1 |
| Watson, S | 1 |
| Vidlin, SH | 1 |
| Grundmark, B | 1 |
| Lu, L | 1 |
| Zheng, X | 1 |
| Wang, S | 1 |
| Tang, C | 1 |
| Zhang, Y | 1 |
| Yao, G | 1 |
| Zeng, J | 1 |
| Ge, S | 1 |
| Wen, H | 1 |
| Xu, M | 1 |
| Guyatt, G | 1 |
| Xu, N | 1 |
| Parfenov, АI | 1 |
| Belostotsky, NI | 1 |
| Khomeriki, SG | 1 |
| Akhmadullina, OV | 1 |
| Bykova, SV | 1 |
| Sabelnikova, EA | 1 |
| Dbar, SR | 1 |
| Ringash, J | 1 |
| Au, HJ | 1 |
| Siu, LL | 1 |
| Shapiro, JD | 1 |
| Jonker, DJ | 1 |
| Zalcberg, JR | 1 |
| Moore, MJ | 1 |
| Strickland, A | 1 |
| Kotb, R | 1 |
| Jeffery, M | 1 |
| Alcindor, T | 1 |
| Ng, S | 1 |
| Salim, M | 1 |
| Sabesan, S | 1 |
| Easaw, JC | 1 |
| Shannon, J | 1 |
| El-Tahche, F | 1 |
| Walters, I | 1 |
| Tu, D | 1 |
| O'Callaghan, CJ | 1 |
| Vail, DM | 1 |
| Thamm, DH | 1 |
| Reiser, H | 1 |
| Ray, AS | 1 |
| Wolfgang, GH | 1 |
| Watkins, WJ | 1 |
| Babusis, D | 1 |
| Henne, IN | 1 |
| Hawkins, MJ | 1 |
| Kurzman, ID | 1 |
| Jeraj, R | 1 |
| Vanderhoek, M | 1 |
| Plaza, S | 1 |
| Anderson, C | 1 |
| Wessel, MA | 1 |
| Robat, C | 1 |
| Lawrence, J | 1 |
| Tumas, DB | 1 |
| Sharma, P | 1 |
| Perri, RE | 1 |
| Sirven, JE | 1 |
| Zeldenrust, SR | 1 |
| Brandhagen, DJ | 1 |
| Rosen, CB | 1 |
| Douglas, DD | 1 |
| Mulligan, DC | 1 |
| Rakela, J | 1 |
| Wiesner, RH | 1 |
| Balan, V | 1 |
| Bartholdi, D | 1 |
| Zumsteg, D | 1 |
| Verrips, A | 1 |
| Wevers, RA | 1 |
| Sistermans, E | 1 |
| Hess, K | 1 |
| Jung, HH | 1 |
| Gookin, JL | 1 |
| Foster, DM | 1 |
| Coccaro, MR | 1 |
| Stauffer, SH | 1 |
| Creagan, ET | 1 |
| O'Connell, MJ | 1 |
| Kovach, JS | 1 |
| Leichus, LS | 1 |
| Goldhill, JM | 1 |
| Long, JD | 1 |
| Percy, WH | 1 |
| Shaw, RD | 1 |
| Donovan, V | 1 |
| Burakoff, R | 1 |
| Sazawal, S | 1 |
| Bhatnagar, S | 1 |
| Bhan, MK | 1 |
| Saxena, SK | 1 |
| Arora, NK | 1 |
| Aggarwal, SK | 1 |
| Kashyap, DK | 1 |
| Wapnir, RA | 2 |
| Zdanowicz, MM | 2 |
| Teichberg, S | 2 |
| Lifshitz, F | 2 |
| Bennish, ML | 1 |
| Azad, AK | 1 |
| Rahman, O | 1 |
| Phillips, RE | 1 |
| Patra, FC | 1 |
| Sack, DA | 1 |
| Islam, A | 1 |
| Alam, AN | 1 |
| Mazumder, RN | 1 |
| Stanley, RJ | 1 |
| Melson, GL | 1 |
| Cubillo, E | 1 |
| Hesker, AE | 1 |
Reviews
1 review available for alanine and Diarrhea
| Article | Year |
|---|---|
Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis.
Topics: Acitretin; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal, Humanized; Anx | 2020 |
Trials
4 trials available for alanine and Diarrhea
| Article | Year |
|---|---|
Quality of life in patients with K-RAS wild-type colorectal cancer: the CO.20 phase 3 randomized trial.
Topics: Alanine; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuxima | 2014 |
Alanine-based oral rehydration solution: assessment of efficacy in acute noncholera diarrhea among children.
Topics: Acute Disease; Alanine; Child, Preschool; Cholera; Diarrhea; Diarrhea, Infantile; Double-Blind Metho | 1991 |
Oral rehydration formula containing alanine and glucose for treatment of diarrhoea: a controlled trial.
Topics: Adolescent; Adult; Alanine; Bicarbonates; Child; Cholera; Clinical Trials as Topic; Diarrhea; Double | 1989 |
A comparison of three cholecystographic agents. A double-blind study with and without a prior fatty meal.
Topics: Alanine; Butyrates; Cholecystography; Clinical Trials as Topic; Contrast Media; Diarrhea; Dietary Fa | 1974 |
Other Studies
12 other studies available for alanine and Diarrhea
| Article | Year |
|---|---|
Direct endothelial damage and vasculitis due to SARS-CoV-2 in small bowel submucosa of COVID-19 patient with diarrhea.
Topics: Adenosine Monophosphate; Adult; Alanine; Antibodies, Monoclonal, Humanized; Antiviral Agents; COVID- | 2021 |
Sex Differences in Reported Adverse Drug Reactions to COVID-19 Drugs in a Global Database of Individual Case Safety Reports.
Topics: Abdominal Pain; Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antiviral Agent | 2020 |
Rebamipide increases the disaccharidases activity in patients with enteropathy with impaired membrane digestion. Pilot study.
Topics: Adolescent; Adult; Alanine; Case-Control Studies; Constipation; Diarrhea; Disaccharidases; Female; H | 2019 |
Assessment of GS-9219 in a pet dog model of non-Hodgkin's lymphoma.
Topics: Alanine; Animals; Animals, Domestic; Anorexia; Antineoplastic Agents; Area Under Curve; Diarrhea; Di | 2009 |
Outcome of liver transplantation for familial amyloidotic polyneuropathy.
Topics: Adult; Alanine; Amyloid Neuropathies, Familial; Diarrhea; Female; Glycine; Humans; Liver Transplanta | 2003 |
Spinal phenotype of cerebrotendinous xanthomatosis--a pitfall in the diagnosis of multiple sclerosis.
Topics: Age of Onset; Alanine; Bile Acids and Salts; Cholestanetriol 26-Monooxygenase; Cholestanol; Choleste | 2004 |
Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets.
Topics: Alanine; Analysis of Variance; Animals; Animals, Newborn; Arginine; Atrophy; Chlorides; Cryptosporid | 2008 |
A Phase I study of the combination N-(phosphonacetyl)-L-aspartate (PALA, NSC-224131) and L-alanosine (NSC-153353) in patients with advanced cancer.
Topics: Alanine; Aspartic Acid; Diarrhea; Digestive System Neoplasms; Drug Administration Schedule; Drug Eva | 1983 |
Effects of rotavirus on epithelial transport in rabbit small intestine.
Topics: Alanine; Animals; Biological Transport; Cells, Cultured; Diarrhea; Dinoprostone; Disease Models, Ani | 1994 |
Alanine stimulation of water and sodium absorption in a model of secretory diarrhea.
Topics: Absorption; Alanine; Animals; Diarrhea; Disease Models, Animal; Fluid Therapy; Intestinal Absorption | 1990 |
Hypoglycemia during diarrhea in childhood. Prevalence, pathophysiology, and outcome.
Topics: Adolescent; Alanine; Aspartate Aminotransferases; Bilirubin; Blood Glucose; C-Peptide; Child; Child, | 1990 |
Oral hydration solutions in experimental osmotic diarrhea: enhancement by alanine and other amino acids and oligopeptides.
Topics: Absorption; Alanine; Amino Acids; Animals; Cathartics; Diarrhea; Drug Synergism; Fluid Therapy; Gluc | 1988 |