Page last updated: 2024-11-08

alanine and Diarrhea

alanine has been researched along with Diarrhea in 17 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.

Research Excerpts

ExcerptRelevanceReference
"Results of these studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C."7.74Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets. ( Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH, 2008)
"20 trial randomized patients with K-RAS wild-type, chemotherapy-refractory, metastatic colorectal cancer to receive cetuximab (CET) plus brivanib alaninate (BRIV) or CET plus placebo (CET/placebo)."5.19Quality of life in patients with K-RAS wild-type colorectal cancer: the CO.20 phase 3 randomized trial. ( Alcindor, T; Au, HJ; Easaw, JC; El-Tahche, F; Jeffery, M; Jonker, DJ; Kotb, R; Moore, MJ; Ng, S; O'Callaghan, CJ; Ringash, J; Sabesan, S; Salim, M; Shannon, J; Shapiro, JD; Siu, LL; Strickland, A; Tu, D; Walters, I; Zalcberg, JR, 2014)
"Oral rehydration solution containing L-alanine was considerably better than standard oral rehydration solution at reducing the severity of symptoms and the need for fluid of male patients with diarrhoea associated with V cholerae and enterotoxigenic E coli."5.06Oral rehydration formula containing alanine and glucose for treatment of diarrhoea: a controlled trial. ( Alam, AN; Islam, A; Mazumder, RN; Patra, FC; Sack, DA, 1989)
"Results of these studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C."3.74Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets. ( Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH, 2008)
"We conclude that hypoglycemia is a major cause of death in association with diarrhea."1.28Hypoglycemia during diarrhea in childhood. Prevalence, pathophysiology, and outcome. ( Azad, AK; Bennish, ML; Phillips, RE; Rahman, O, 1990)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's4 (23.53)18.2507
2000's4 (23.53)29.6817
2010's2 (11.76)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Carnevale, S1
Beretta, P1
Morbini, P1
Zekarias, A1
Watson, S1
Vidlin, SH1
Grundmark, B1
Lu, L1
Zheng, X1
Wang, S1
Tang, C1
Zhang, Y1
Yao, G1
Zeng, J1
Ge, S1
Wen, H1
Xu, M1
Guyatt, G1
Xu, N1
Parfenov, АI1
Belostotsky, NI1
Khomeriki, SG1
Akhmadullina, OV1
Bykova, SV1
Sabelnikova, EA1
Dbar, SR1
Ringash, J1
Au, HJ1
Siu, LL1
Shapiro, JD1
Jonker, DJ1
Zalcberg, JR1
Moore, MJ1
Strickland, A1
Kotb, R1
Jeffery, M1
Alcindor, T1
Ng, S1
Salim, M1
Sabesan, S1
Easaw, JC1
Shannon, J1
El-Tahche, F1
Walters, I1
Tu, D1
O'Callaghan, CJ1
Vail, DM1
Thamm, DH1
Reiser, H1
Ray, AS1
Wolfgang, GH1
Watkins, WJ1
Babusis, D1
Henne, IN1
Hawkins, MJ1
Kurzman, ID1
Jeraj, R1
Vanderhoek, M1
Plaza, S1
Anderson, C1
Wessel, MA1
Robat, C1
Lawrence, J1
Tumas, DB1
Sharma, P1
Perri, RE1
Sirven, JE1
Zeldenrust, SR1
Brandhagen, DJ1
Rosen, CB1
Douglas, DD1
Mulligan, DC1
Rakela, J1
Wiesner, RH1
Balan, V1
Bartholdi, D1
Zumsteg, D1
Verrips, A1
Wevers, RA1
Sistermans, E1
Hess, K1
Jung, HH1
Gookin, JL1
Foster, DM1
Coccaro, MR1
Stauffer, SH1
Creagan, ET1
O'Connell, MJ1
Kovach, JS1
Leichus, LS1
Goldhill, JM1
Long, JD1
Percy, WH1
Shaw, RD1
Donovan, V1
Burakoff, R1
Sazawal, S1
Bhatnagar, S1
Bhan, MK1
Saxena, SK1
Arora, NK1
Aggarwal, SK1
Kashyap, DK1
Wapnir, RA2
Zdanowicz, MM2
Teichberg, S2
Lifshitz, F2
Bennish, ML1
Azad, AK1
Rahman, O1
Phillips, RE1
Patra, FC1
Sack, DA1
Islam, A1
Alam, AN1
Mazumder, RN1
Stanley, RJ1
Melson, GL1
Cubillo, E1
Hesker, AE1

Reviews

1 review available for alanine and Diarrhea

ArticleYear
Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis.
    Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:12

    Topics: Acitretin; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal, Humanized; Anx

2020

Trials

4 trials available for alanine and Diarrhea

ArticleYear
Quality of life in patients with K-RAS wild-type colorectal cancer: the CO.20 phase 3 randomized trial.
    Cancer, 2014, Jan-15, Volume: 120, Issue:2

    Topics: Alanine; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuxima

2014
Alanine-based oral rehydration solution: assessment of efficacy in acute noncholera diarrhea among children.
    Journal of pediatric gastroenterology and nutrition, 1991, Volume: 12, Issue:4

    Topics: Acute Disease; Alanine; Child, Preschool; Cholera; Diarrhea; Diarrhea, Infantile; Double-Blind Metho

1991
Oral rehydration formula containing alanine and glucose for treatment of diarrhoea: a controlled trial.
    BMJ (Clinical research ed.), 1989, May-20, Volume: 298, Issue:6684

    Topics: Adolescent; Adult; Alanine; Bicarbonates; Child; Cholera; Clinical Trials as Topic; Diarrhea; Double

1989
A comparison of three cholecystographic agents. A double-blind study with and without a prior fatty meal.
    Radiology, 1974, Volume: 112, Issue:3

    Topics: Alanine; Butyrates; Cholecystography; Clinical Trials as Topic; Contrast Media; Diarrhea; Dietary Fa

1974

Other Studies

12 other studies available for alanine and Diarrhea

ArticleYear
Direct endothelial damage and vasculitis due to SARS-CoV-2 in small bowel submucosa of COVID-19 patient with diarrhea.
    Journal of medical virology, 2021, Volume: 93, Issue:1

    Topics: Adenosine Monophosphate; Adult; Alanine; Antibodies, Monoclonal, Humanized; Antiviral Agents; COVID-

2021
Sex Differences in Reported Adverse Drug Reactions to COVID-19 Drugs in a Global Database of Individual Case Safety Reports.
    Drug safety, 2020, Volume: 43, Issue:12

    Topics: Abdominal Pain; Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antiviral Agent

2020
Rebamipide increases the disaccharidases activity in patients with enteropathy with impaired membrane digestion. Pilot study.
    Terapevticheskii arkhiv, 2019, Mar-18, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Alanine; Case-Control Studies; Constipation; Diarrhea; Disaccharidases; Female; H

2019
Assessment of GS-9219 in a pet dog model of non-Hodgkin's lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, May-15, Volume: 15, Issue:10

    Topics: Alanine; Animals; Animals, Domestic; Anorexia; Antineoplastic Agents; Area Under Curve; Diarrhea; Di

2009
Outcome of liver transplantation for familial amyloidotic polyneuropathy.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2003, Volume: 9, Issue:12

    Topics: Adult; Alanine; Amyloid Neuropathies, Familial; Diarrhea; Female; Glycine; Humans; Liver Transplanta

2003
Spinal phenotype of cerebrotendinous xanthomatosis--a pitfall in the diagnosis of multiple sclerosis.
    Journal of neurology, 2004, Volume: 251, Issue:1

    Topics: Age of Onset; Alanine; Bile Acids and Salts; Cholestanetriol 26-Monooxygenase; Cholestanol; Choleste

2004
Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets.
    Journal of pediatric gastroenterology and nutrition, 2008, Volume: 46, Issue:2

    Topics: Alanine; Analysis of Variance; Animals; Animals, Newborn; Arginine; Atrophy; Chlorides; Cryptosporid

2008
A Phase I study of the combination N-(phosphonacetyl)-L-aspartate (PALA, NSC-224131) and L-alanosine (NSC-153353) in patients with advanced cancer.
    Cancer, 1983, Aug-15, Volume: 52, Issue:4

    Topics: Alanine; Aspartic Acid; Diarrhea; Digestive System Neoplasms; Drug Administration Schedule; Drug Eva

1983
Effects of rotavirus on epithelial transport in rabbit small intestine.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:10

    Topics: Alanine; Animals; Biological Transport; Cells, Cultured; Diarrhea; Dinoprostone; Disease Models, Ani

1994
Alanine stimulation of water and sodium absorption in a model of secretory diarrhea.
    Journal of pediatric gastroenterology and nutrition, 1990, Volume: 10, Issue:2

    Topics: Absorption; Alanine; Animals; Diarrhea; Disease Models, Animal; Fluid Therapy; Intestinal Absorption

1990
Hypoglycemia during diarrhea in childhood. Prevalence, pathophysiology, and outcome.
    The New England journal of medicine, 1990, May-10, Volume: 322, Issue:19

    Topics: Adolescent; Alanine; Aspartate Aminotransferases; Bilirubin; Blood Glucose; C-Peptide; Child; Child,

1990
Oral hydration solutions in experimental osmotic diarrhea: enhancement by alanine and other amino acids and oligopeptides.
    The American journal of clinical nutrition, 1988, Volume: 48, Issue:1

    Topics: Absorption; Alanine; Amino Acids; Animals; Cathartics; Diarrhea; Drug Synergism; Fluid Therapy; Gluc

1988